Associate Scientist/Scientist, Analytical Chemistry California
12/15/2014 11:18 AM

The CMC group at Dart NeuroScience is seeking an Analytical Scientist to perform analytical activities in support of Dart small molecule drug substances (NCEs) and drug products. The position will work closely with internal Process Chemistry and Formulation Development functions and with external contract organizations. •Perform analytical activities for small molecule APIs/NCEs and drug product  ...View Job
Associate Scientist/Scientist, CMC California
12/15/2014 11:18 AM

Reporting to the Associate Director, the successful candidate will be responsible for implementing CMC strategies, as well as coordinating many aspects of CMC regulatory submissions. This person will work closely with the clinical team, particularly with Regulatory Affairs, to help define the CMC role in all drug development programs. Specific responsibilities may include identifying and negotiat  ...View Job
Research Associate, Molecular Biology California-San Diego
12/15/2014 11:14 AM

DNS is seeking an energetic and highly motivated Research Associate to join our molecular biology group in the structural biology department. The candidate will work as part of a team of scientists generating and evaluation DNA constructs that will be used to express proteins under milligram-scale quantities for macromolecular crystallography studies. Major responsibilities will include DNA cons  ...View Job
Sr. Clinical/Clinical Scientist California-San Diego
12/15/2014 11:13 AM

DNS is seeking a motivated research professional to participate in all aspects of planning, implementing, managing and reporting of clinical studies, under the supervision of the department director, or designee. This individual will provide key overall scientific and/or logistical support to clinical development programs in general. • Assist in or design, author and/or review clinical study  ...View Job
Senior Scientist, DMPK California-San Diego
12/15/2014 11:12 AM

Dart NeuroScience LLC (DNS) is seeking an experienced DMPK scientist to conduct, lead and manage bioanalytical/pharmacokinetic studies to understand and characterize the potential drug candidates. A thorough understanding and integration of the theoretical and technical aspects of bioanalytical/ADMET technologies is required. Experience with automation is preferred. Responsibilities include str  ...View Job
Scientist, DMPK California-San Diego
12/15/2014 11:11 AM

Dart NeuroScience LLC (DNS) is seeking an experienced DMPK scientist to conduct, lead and manage metabolite identification and profiling studies in in vitro systems (liver microsomes, S9, plasma, hepatocytes, etc.) and in vivo systems (mice, rat, dog, monkey, human). Other job duties are to design, lead and manage in vitro and in vivo studies to understand and characterize the absorption, distrib  ...View Job
Scientist, In Vivo Pharmacology: Disease Model Development California-San Diego
12/15/2014 11:11 AM

DNS’s In Vivo Pharmacology group focuses on development of rodent CNS disease models, preclinical safety / toxicology and behavioral profiling of candidate molecules. We are seeking a Ph.D. with a background in CNS rodent model development and a minimum of two years pharmaceutical industry experience. The scientist will be responsible for the development of rodent disease models (including stro  ...View Job
Associate Director, Toxicology California-San Diego
12/15/2014 11:10 AM

•Develop and oversee non-clinical safety and toxicology drug development plans for small molecule CNS compounds with estimated costs, timing, and risk assessment/management •Identify and resolve nonclinical study operational issues and maintain project timelines •Develop safety-related issue mitigation or resolution plans and coordinate execution of the experimental plan as required •Interact w  ...View Job
Spotfire Software Engineer California-San Diego
12/15/2014 11:09 AM

The Scientific Computing department at DNS is looking for a Spotfire development and support engineer. DNS is seeking to leverage its investment in the Spotfire platform, to more effectively support chemists, biologists, and clinical data analysts. DNS uses Spotfire to represent and visualize data arising from many sources, including these. •Chemical structures •Biological sequences •Laborato  ...View Job
Software Engineer California-San Diego
12/15/2014 11:08 AM

Dart NeuroScience LLC (DNS) is a private company with its principal place of business in San Diego CA. DNS will discover new technologies and develop new therapies to help maintain cognitive vitality throughout life. DNS’s Scientific Computing department has broad responsibility for (i) development of novel bioinformatics tools to facilitate gene discovery, (ii) development of novel software met  ...View Job