Scientist, Structural Biology California
8/24/2015 10:28 AM

DNS is seeking a highly motivated and experienced NMR spectroscopist to join the Structural Biology Department. The candidate will be responsible to screen fragment-based libraries by NMR and deliver high-quality 1D, 2D or 3D structural information to investigate and characterize protein-ligand interactions in order to guide structure-based drug design. Demonstrated success and expert knowledge  ...View Job
Scientist, In Vivo Pharmacology California-San Diego
8/24/2015 8:43 AM

DNS’s In Vivo Pharmacology group focuses on development of rodent CNS models, preclinical safety / toxicology and behavioral profiling of candidate molecules. We are seeking a Ph.D. with a background in CNS rodent model development and a minimum of two years pharmaceutical industry experience. The scientist will be responsible for the development of rodent models (including stroke) to support t  ...View Job
Senior Clinical Data Manager California
8/20/2015 4:06 PM

The Senior Clinical Data Manager (Sr. CDM) will provide oversight of, assist in the coordination of, and/or partake directly in the data management activities from study start-up, data processing, and database close-out in a paper or electronic environment for projects sponsored by DNS where the activities are conducted in-house or by CROs. In addition, the Sr. CDM may be responsible for designin  ...View Job
Senior Manager, Regulatory Affairs California
8/19/2015 4:53 PM

Working in a team environment, the Regulatory Affairs Senior Manager will be responsible for executing regulatory strategy as well as hands-on management of all technical and operational aspects related to the regulatory lifecycle (e.g., from preclinical candidate designation through registration) of assigned DNS products. Strategic Planning • Represent the Regulatory Affairs department on mu  ...View Job
Senior Associate Scientist/Scientist, Structure Guided Chemistry California
8/19/2015 12:39 PM

The successful Senior Associate Scientist/Scientist candidate will be an accomplished synthetic/analytical chemist with state of the art knowledge of modern high throughput purification of chiral and achiral small molecules. The individual will be a motivated, creative, hands-on laboratory scientist with the ability to interact effectively with team members in all areas of drug discovery. Major r  ...View Job
Research Associate/Associate Scientist, Structural Biology California
8/18/2015 10:29 AM

DNS is seeking an energetic and highly motivated research associate to join the large-scale protein production group within the structural biology department. The candidate will work as part of a team of scientists to support the recombinant production of proteins in milligram-scale quantities for macromolecular crystallographic studies. Major responsibilities will include protein expression in   ...View Job
Scientist III, In Vitro Pharmacology California
8/14/2015 9:55 AM

The successful candidate will be responsible for managing the daily operations of the In Vitro Pharmacology group. These responsibilities include 1) managing in vivo rodent Receptor Occupancy activities, radioligand characterization 2) development of translatable CNS biomarkers, 3) motivating and developing a team of PhD and associate scientists. Responsibilities may also include management of a  ...View Job
Scientist, DMPK California
8/10/2015 10:12 AM

Dart NeuroScience LLC (DNS) is seeking an experienced scientist to design and conduct metabolite identification and profiling studies using in-vitro systems (liver microsomes, S9, hepatocytes, etc.), and in-vivo systems (plasma, urine, bile, etc.). The successful candidate must have superior knowledge and experience in structural elucidation using accurate mass, and MSn. In addition, he/she will  ...View Job
Scientist, Computational Chemistry California-San Diego
8/10/2015 10:11 AM

This is an entry-level PhD scientist position. The successful candidate will be an accomplished computational chemist with state of the art knowledge of computational chemistry as it is applied to small-molecule drug discovery. The successful candidate must be a motivated, creative, hands-on scientist with the ability to interact effectively with team members in all areas of drug discovery. Majo  ...View Job
Manager, Clinical Operations California
8/5/2015 9:23 AM

•Manage the day-to-day activities necessary for the successful completion of clinical programs according to the clinical study protocol, DNS Standard Operating Procedures, ICH Guidelines and GCP. •Oversight of CROs, vendors and contract personnel. •May have some site monitoring or co-monitoring responsibility. •All aspects of designated clinical study operations with accountability for meeting   ...View Job