Research Associate, Molecular Biology California-San Diego
9/23/2014 9:43 AM

DNS is seeking an energetic and highly motivated Research Associate to join our molecular biology group in the structural biology department. The candidate will work as part of a team of scientists generating and evaluation DNA constructs that will be used to express proteins under milligram-scale quantities for macromolecular crystallography studies. Major responsibilities will include DNA cons  ...View Job
Scientist California-San Diego
9/23/2014 8:51 AM

We are seeking a Senior Scientist with a background in Behavioral Neuroscience and significant experience in small molecule drug discovery. The scientist will lead behavioral Pharmacology studies and assay development in support of lead discovery. The preferred candidate will have demonstrated the ability to conduct creative and productive research and will implement in vivo behavioral techniques  ...View Job
Scientist, Neurophysiology California-San Diego
9/22/2014 2:39 PM

DNS is seeking a PhD with a strong background in synaptic physiology. The researcher will investigate the role of regulators of memory formation in synaptic function and plasticity in support of our target discovery and drug development programs. The preferred candidate will have demonstrated ability to conduct creative and productive research in an academic or industry environment. The candidat  ...View Job
Scientist - Bioinformatics, Pathway Specialist California-San Diego
9/19/2014 11:47 AM

The Bioinformatics Group supports the DNS drug discovery process by: 1) building innovative tools to support the drug discovery process; 2) designing and implementing scientific algorithms to analyze data; 3) providing support to project teams such as our in-house target discovery team. The Bioinformatics Scientist will have broad hands-on experience in bioinformatics with strong problem solving  ...View Job
Scientist, Crystallography California-San Diego
9/19/2014 11:12 AM

DNS is seeking a highly motivated and experienced protein crystallographer to join the structural biology department. The candidate will be responsible for the delivery of high-resolution 3D structural information on soluble and membrane protein complexes to guide structure-based drug design. Demonstrated success in the crystallization and structure determination of soluble and membrane protein s  ...View Job
Scientist, In Vitro Pharmacology California-San Diego
9/16/2014 10:44 AM

DNS is seeking a Research Scientist to develop pharmodynamic (PD) biomarker assays for use in pre-clinical and clinical research to evaluate target-engagement, mechanism of action, and disease modification. The candidate will design and execute in vivo/ex vivo/in vitro experiments, provide scientific and creative leadership, demonstrate excellent communication and interpersonal skills, and may be   ...View Job
Associate Scientist/Scientist, CMC California-San Diego
9/15/2014 2:58 PM

Reporting to the Associate Director, the successful candidate will be responsible for implementing CMC strategies, as well as coordinating many aspects of CMC regulatory submissions. This person will work closely with the clinical team, particularly with Regulatory Affairs, to help define the CMC role in all drug development programs. Specific responsibilities may include identifying and negotiat  ...View Job
Scientist, Structure Guided Chemistry California-San Diego
9/12/2014 11:37 AM

The successful candidate will be an accomplished synthetic/medicinal chemist with state of the art knowledge of synthetic organic chemistry and high-throughput parallel synthesis techniques, as applied to small-molecule drug discovery. Talents should be exemplified by publications, presentations, and/or patents demonstrating complex problem solving in organic synthesis. Successful candidates wil  ...View Job
Research Associate, Structural Biology California-San Diego
9/2/2014 10:31 AM

DNS is seeking a motivated Research Associate with a strong background in automated high-throughput protein crystallization for the structural biology department. The candidate is required to have broad technical background and expertise in state-of-the-art automated high-throughput protein crystallization processes and robotics. Major responsibilities will hold all aspects of protein crystal  ...View Job