IPOs


Recent IPO  IPO Withdrawn

Filing Date

Name

Ticker

Price Range

Issue Size

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Est. Market Value

Aug 7, 2013 Acceleron Pharma N/A N/A N/A $74.75M N/A N/A

Lead Underwriter

Citigroup and Leerink Swann LLC will act as joint book-running managers for the offering. Piper Jaffray & Co. will act as lead manager and JMP Securities will act as co-managers.

Description

Acceleron is a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of novel protein therapeutics for cancer and rare diseases.


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April 15, 2013 Portola Pharmaceuticals, Inc. N/A N/A N/A $115M N/A N/A

Lead Underwriter

Morgan Stanley and Credit Suisse

Description

Portola is a biopharmaceutical company focused on the development and commercialization of novel therapeutics in the areas of thrombosis, other hematologic disorders and inflammation for patients who currently have limited or no approved treatment options.


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April 2, 2013 Chimerix, Inc. N/A N/A N/A 13 to $15 per share N/A N/A

Lead Underwriter

Morgan Stanley and Cowen & Company

Description

Chimerix is a biopharmaceutical company developing oral antiviral therapeutics for CMV.


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January 21, 2013 Zoetis, Inc. N/A N/A N/A $22-$25 per share N/A N/A

Lead Underwriter

JP Morgan, BofA Merrill Lynch and Morgan Stanley

Description

Zoetis, formerly a business unit of Pfizer, is a global animal health company dedicated to supporting customers and their businesses in ever better ways.


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July 26, 2011 Horizon Pharma, Inc. N/A N/A N/A $10 to $12 per share N/A N/A

Lead Underwriter

N/A

Description

Horizon Pharma, Inc. is a specialty pharmaceutical company that has developed and is commercializing DUEXIS and RAYOS/LODOTRA, both of which target unmet therapeutic needs in arthritis, pain and inflammatory diseases.


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June 1, 2011 Myriant Technologies LLC N/A N/A N/A $125M N/A N/A

Lead Underwriter

UBS Securities LLC, J.P. Morgan Securities LLC, Citigroup Global Markets Inc. and Piper Jaffray & Co.

Description

Myriant is an industrial biotech company focused on production of bio-based chemicals that substitute for petroleum-based chemicals .


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May 27, 2011 Solazyme, Inc. N/A N/A N/A $18 per share N/A N/A

Lead Underwriter

Morgan Stanley & Co. Inc. and Goldman, Sachs & Co.

Description

Solazyme, Inc. (SZYM) is a renewable oil and bioproducts company that transforms a range of low-cost plant-based sugars into high-value oils.


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Dec 6, 2010 Fluidigm Corporation N/A N/A N/A $86M N/A N/A

Lead Underwriter

Deutsche Bank Securities Inc. and Piper Jaffray & Co. are acting as book-runners for the offering.

Description

Fluidigm is a biotech tools company that creates microfluidic-based chips and instrumentation for biological research.


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Dec 6, 2010 Fluidigm Corporation N/A N/A N/A $86M N/A N/A

Lead Underwriter

Deutsche Bank Securities Inc. and Piper Jaffray & Co. are acting as book-runners for the offering.

Description

Fluidigm is a biotech tools company that creates microfluidic-based chips and instrumentation for biological research.


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Dec 1, 2010 Anacor Pharmaceuticals, Inc. N/A N/A N/A $70M N/A N/A

Lead Underwriter

Citi and Deutsche Bank Securities Inc. acted as joint book-running managers for the initial public offering, and Cowen and Company, LLC and Wedbush PacGrow Life Sciences acted as co-managers.

Description

Anacor is a biopharmaceutical company focused on discovering, developing and commercializing novel small-molecule therapeutics derived from its boron chemistry platform.


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Nov 23, 2010 Clarus Therapeutics N/A N/A N/A $86M N/A N/A

Lead Underwriter

N/A

Description

Clarus is a privately held biopharmaceutical company whose focus is the development and commercialization of androgen-based prescription drug products for men and women.


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Nov 15, 2010 AcelRx Pharmaceuticals N/A N/A N/A $6 Per Share N/A N/A

Lead Underwriter

Piper Jaffray & Co. is acting as sole book-running manager. Canaccord Genuity Inc., Cowen and Company, LLC and JMP Securities are acting as co-managers for the offering.

Description

AcelRx Pharmaceuticals is a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute and breakthrough pain.


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Nov 11, 2010 Complete Genomics N/A N/A N/A $54M N/A N/A

Lead Underwriter

N/A

Description

Complete Genomics is a life sciences company that has developed and commercialized an innovative DNA sequencing platform.


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Nov 5, 2010 Zogenix, Inc. N/A N/A N/A $78M N/A N/A

Lead Underwriter

Wells Fargo Securities, Leerink Swann, Oppenheimer & Co., and Stifel Nicolaus Weisel

Description

Zogenix is a pharmaceutical company commercializing and developing products for the treatment of central nervous system disorders and pain.


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Oct 27, 2010 Pacific Biosciences N/A N/A N/A $200M N/A N/A

Lead Underwriter

J.P. Morgan Securities LLC and Morgan Stanley & Co. Incorporated are acting as joint book-running managers for the offering. Deutsche Bank Securities Inc. and Piper Jaffray & Co. are acting as co-managers for the offering.

Description

Pacific Biosciences' mission is to transform the way humankind acquires, processes and interprets data from living systems through the design, development and commercialization of innovative tools for biological research.


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Oct 25, 2010 Aegerion Pharmaceuticals, Inc. N/A N/A N/A $9.50 Per Share N/A N/A

Lead Underwriter

Leerink Swann LLC and Lazard Capital Markets LLC are acting as joint book-running managers for the offering. Needham & Company, LLC, Canaccord Genuity Inc. and Collins Stewart LLC are acting as co-managers for the offering.

Description

Aegerion Pharmaceuticals is an emerging biopharmaceutical company focused on the development and commercialization of novel therapeutics to treat severe lipid disorders.


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Sep 28, 2010 Amyris N/A N/A N/A $84.8M N/A N/A

Lead Underwriter

N/A

Description

Amyris is building an integrated renewable products company. Founded in 2003 and based in Emeryville, CA, Amyris is using breakthrough science and an innovative business model to address some of our planet’s most daunting problems.


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Aug 18, 2010 Endocyte, Inc. N/A N/A N/A $86.3M N/A N/A

Lead Underwriter

The joint book-running managers of the proposed offering will be RBC Capital Markets and Leerink Swann LLC. Wedbush PacGrow Life Sciences and Baird are acting as co-managers for the offering.

Description

Endocyte, Inc. is a biopharmaceutical company developing targeted therapies for the treatment of cancer and inflammatory diseases.


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Jul 19, 2010 Epocrates Inc. N/A N/A N/A $75M N/A N/A

Lead Underwriter

J.P. Morgan Securities Inc. and Piper Jaffray & Co. are serving as joint book-running managers for the proposed offering. William Blair & Company, L.L.C. and JMP Securities LLC are acting as co-managers.

Description

Epocrates is a leading provider of mobile drug reference tools and interactive services to healthcare professionals and the healthcare industry.


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Jun 21, 2010 ReSearch Pharmaceutical Services (RPS), Inc. N/A N/A N/A $100M N/A N/A

Lead Underwriter

Jefferies & Co, William Blair & Co and Lazard Capital Markets.

Description

RPS, a next generation CRO, provides comprehensive global Phase 1-4 clinical development solutions to the pharmaceutical, biotechnology and medical device industries.


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May 17, 2010 NuPathe Inc. N/A N/A N/A $86.3M N/A N/A

Lead Underwriter

N/A

Description

Nupathe is a specialty pharmaceutical company focused on the development and commercialization of branded therapeutics for diseases of the central nervous system, including neurological and psychiatric disorders.


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May 14, 2010 Ikaria Inc. N/A N/A N/A $200M N/A N/A

Lead Underwriter

Goldman Sachs and Morgan Stanley serving as co-lead underwriters.

Description

Ikaria is positioned to develop and deliver innovative therapeutics and interventions to meet the needs of critically ill patients.


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Apr 30, 2010 Aurora Diagnostics Inc. N/A N/A N/A $150M N/A N/A

Lead Underwriter

Morgan Stanley, Barclays Capital and UBS Investment Bank

Description

Aurora Diagnostics, LLC is a specialized laboratory company consisting of anatomic pathology and other diagnostic laboratory businesses.


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Apr 7, 2010 Alimera Sciences Inc. N/A $15-17/Per Share N/A $87M N/A N/A

Lead Underwriter

Credit Suisse Securities LLC

Description

Alimera Sciences, Inc., is a biopharmaceutical company that specializes in the research, development and commercialization of prescription ophthalmic pharmaceutical.


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Dec 30, 2009 Med BioGene N/A N/A N/A $24.25M N/A N/A

Lead Underwriter

Rodman & Renshaw, LLC

Description

MBI is a life science company focused on the development and commercialization of genomic-based personalized clinical laboratory diagnostic tests.


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Dec 29, 2009 Codexis Pharmaceuticals N/A N/A N/A $100M N/A N/A

Lead Underwriter

Credit Suisse Securities (USA) LLC and Goldman, Sachs & Co. will be acting as joint book-running managers, with RBC Capital Markets Corporation and Pacific Crest Securities LLC acting as co-managers for the offering.

Description

Codexis, Inc. is a leading provider of optimized biocatalysts that make existing industrial processes faster, cleaner and more efficient than current methods and has the potential to make new industrial processes possible at commercial scale.


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Dec 28, 2009 Tengion Inc. N/A N/A N/A $40.25M N/A N/A

Lead Underwriter

Piper Jaffray & Co. is acting as the sole manager.

Description

Tengion is a clinical-stage company focused on discovering, developing, manufacturing and commercializing a range of replacement organs and tissues, or neo-organs and neo-tissues.


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Dec 17, 2009 AVEO Pharmaceuticals, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

The joint book-running managers of the proposed offering will be J.P. Morgan Securities Inc. and Morgan Stanley & Co. Incorporated. Leerink Swann LLC will be the lead co-manager and Canaccord Adams Inc. will be a co-manager.

Description

AVEO is a biopharmaceutical company focused on discovering, developing and commercializing cancer therapeutics. Its product candidates are targeted against important mechanisms known or believed to be involved in cancer.


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Dec 10, 2009 China Nuokang Bio-Pharmaceutical Inc. N/A N/A N/A $45M N/A N/A

Lead Underwriter

Jefferies & Company acted as the sole bookrunner and Oppenheimer & Co. acted as co-manager for the offering.

Description

Nuokang Bio-Pharmaceutical Inc. (Nasdaq:NKBP) is a leading biopharmaceutical company in China focused on the research, development, manufacture, marketing and sales of hematological and cardiovascular products.


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Nov 9, 2009 Trius Therapeutics N/A N/A N/A $86.25M N/A N/A

Lead Underwriter

Credit Suisse

Description

Trius Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of innovative antibiotics for serious, life-threatening infections.


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Oct 30, 2009 Aldagen Inc. ALDH N/A N/A $80.5M N/A N/A

Lead Underwriter

Cowen and Co, Wachovia Securities, and Pacific Growth Equities

Description

ALDAGEN is a biopharmaceutical company developing proprietary regenerative cell therapies that target significant unmet medical needs. We have four product candidates in clinical trials.


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Sep 16, 2008 Mead Johnson Nutrition Company N/A N/A N/A N/A N/A N/A

Lead Underwriter

Citigroup Global Markets Inc. and Morgan Stanley & Co. Incorporated

Description

Mead Johnson Nutrition helps moms make sure those babies grow up healthy. The company, a subsidiary of pharmaceutical manufacturer Bristol-Myers Squibb (BMS), specializes in making nutritional products for infants and children.


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Jul 25, 2008 AutoGenomics, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

J.P. Morgan Securities Inc., Deutsche Bank Securities Inc., Pacific Growth Equities, LLC and Robert W. Baird & Co.

Description

AutoGenomics Inc., a privately held company based in Carlsbad, CA, has developed the first automated, microarray based multiplexing diagnostic platform that can be used to assess disease signatures with novel genomic and proteomic markers in the area of genetic disorders, infectious disease, cancer and pharmacogenetics.


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Jul 2, 2008 Alimera Sciences Inc. N/A N/A N/A $75M N/A N/A

Lead Underwriter

Credit Suisse, Citi, Cowen and Co, and Leerink Swann

Description

Alimera Sciences, Inc., incorporated on June 4, 2003, is a biopharmaceutical company that specializes in the research, development and commercialization of prescription ophthalmic pharmaceuticals.


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Jun 18, 2008 Genomma N/A N/A N/A N/A N/A N/A

Lead Underwriter

IXE Casa de Bolsa, S.A. de C.V., and Casa de Bolsa Santander, S.A. de C.V.

Description

Genomma Lab Internacional, S.A.B. de C.V. is a leading over-the-counter pharmaceuticals and personal care products company in Mexico. Genomma trades on the Mexican Stock Exchange under the ticker symbol LAB.


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Jun 11, 2008 ZARS, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Cowen and Company and CIBC World Markets are joint book running managers for the offering. Leerink Swann & Company and Susquehanna Financial Group, LLLP are comanagers.

Description

ZARS, Inc. is a specialty pharmaceutical company focused on the development and commercialization of topically applied drugs using its proprietary drug delivery technologies, with an initial focus on pain management.


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Apr 18, 2008 Epocrates, Inc. N/A N/A N/A $75M N/A N/A

Lead Underwriter

Citi, Piper Jaffray, William Blair & Co, and Needham & Co.

Description

Epocrates, Inc. develops clinical information and decision support tools that enable healthcare professionals to find answers more quickly and confidently at the point of care.


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Apr 16, 2008 Fluidigm Corporation N/A N/A N/A N/A N/A N/A

Lead Underwriter

Morgan Stanley & Co. Incorporated is acting as book-running manager, with UBS Investment Bank and Leerink Swann & Company acting as co-managers.

Description

Fluidigm develops, manufactures and markets proprietary Integrated Fluidic Circuit systems for life science research.


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Mar 10, 2008 Bostwick Laboratories N/A N/A N/A $100M N/A N/A

Lead Underwriter

Banc of America Securities LLC, Wachovia Securities, William Blair & Co, and Cowen & Co.

Description

Bostwick Laboratories is a full-service laboratory specializing in uropathology, featuring a staff of board-certified, internationally renowned pathologists dedicated to the diagnosis, treatment and subsequent management of prostate cancer, kidney disease, cancer of the bladder and other urologic conditions.


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Jan 28, 2008 Phenomix Corporation N/A N/A N/A $86.25M N/A N/A

Lead Underwriter

Morgan Stanley, Credit Suisse, Oppenheimer & Co. and Pacific Growth Equities.

Description

Phenomix is a biopharmaceutical company focused on the discovery, development and commercialization of novel small-molecule product candidates directed toward clinically validated targets in significant therapeutic markets.


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Jan 10, 2008 Omeros Corporation N/A N/A N/A $115M N/A N/A

Lead Underwriter

Deutsche Bank Securities Inc. will be acting as the sole book-running manager. Pacific Growth Equities, LLC will be acting as the co- lead manager, and Leerink Swan LLC and Needham & Company, LLC will be acting as co-managers.

Description

Omeros Corporation is a clinical-stage biopharmaceutical company committed to discovering, developing and commercializing products focused on inflammation and disorders of the central nervous system.


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Jan 9, 2008 Bayhill Therapeutics, Inc. N/A N/A N/A $86.25M N/A N/A

Lead Underwriter

Pacific Growth Equities LLC, Lazard Capital Markets, Merriman Curhan Ford & Co and Punk, Ziegel & Co.

Description

Bayhill Therapeutics, Inc. is a clinical-stage biopharmaceutical company using its proprietary therapeutic platform to develop a pipeline of novel products to treat autoimmune diseases in a fundamentally new manner.


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Aug 24, 2007 Precision Therapeutics, Inc. N/A N/A N/A $80.5M N/A N/A

Lead Underwriter

JP Morgan Securities Inc, Piper Jaffray & Co and JMP Securities LLC.

Description

The company develops and commercializes tests intended to assist physicians in individualizing cancer therapy.


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Aug 22, 2007 Adnexus Therapeutics Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Lehman Brothers, UBS Investment Bank, Cowen and Co. and Lazard Capital Markets.

Description

Adnexus Therapeutics is focused on generating vital medicines through the discovery, development, and commercialization of a new class of drugs, Adnectins.


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Aug 21, 2007 BioForm Medical Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

JPMorgan, Piper Jaffray, CIBC World Markets and Jefferies & Company.

Description

BioForm Medical, Inc. is a privately-held medical aesthetics company headquartered in San Mateo, California.


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Aug 14, 2007 Biolex, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Lehman Brothers Inc. and Deutsche Bank Securities Inc. are acting as joint book-running managers and Leerink Swann & Co., Inc. is acting as co-manager for the offering.

Description

Biolex is a clinical-stage biopharmaceutical company that uses its patented LEX System(SM) to develop hard-to-make therapeutic proteins and to optimize monoclonal antibodies.


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Aug 10, 2007 Reliant Pharmaceuticals, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Goldman, Sachs & Co. and Merrill Lynch & Co. will act as the joint lead managers and joint book-runners for the proposed offering.

Description

Reliant Pharmaceuticals is a pharmaceutical company that specializes in the development, commercialization and marketing of prescription therapeutic products.


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Aug 10, 2007 Novabay Pharmaceuticals NBY $4-$6 N/A N/A N/A N/A

Lead Underwriter

Dundee Securities Inc. and Blackmont Capital Corp., among others, are underwriting the IPO.

Description

NovaBay Pharmaceuticals is a clinical-stage pharmaceutical company developing a new class of compounds: The Aganocide™ compounds.


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Aug 7, 2007 BG Medicine BGMDX N/A N/A N/A N/A N/A

Lead Underwriter

Cowen International Limited and Fortis will be acting as joint global coordinators and joint book-runners for the offering. Leerink Swann & Company will act as co-manager.

Description

BG Medicine is a life sciences company focused on the discovery, development and commercialization of novel molecular diagnostics based on biomarkers to improve patient outcomes and contain healthcare costs.


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Aug 3, 2007 Sucampo Pharmaceuticals, Inc. SCMP $11.50 N/A N/A N/A N/A

Lead Underwriter

Cowen and Company, LLC is acting as the book-running manager for the offering and CIBC World Markets Corp. and Leerink Swann & Company are acting as co-managers.

Description

Sucampo is an emerging pharmaceutical company focused on the discovery, development and commercialization of proprietary drugs based on prostones, a class of compounds derived from functional fatty acids that occur naturally in the human body.


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Jul 30, 2007 Talecris Biotherapeutics Holdings Corp. TLCR N/A N/A $1B N/A N/A

Lead Underwriter

Morgan Stanley, Goldman Sachs & Co. and JPMorgan.

Description

Talecris Biotherapeutics discovers, develops, and produces critical care treatments for people with life-threatening disorders in a variety of therapeutic areas including immunology, pulmonology, and hemostasis.


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Jul 13, 2007 Bioheart, Inc. N/A N/A N/A $45M N/A N/A

Lead Underwriter

BMO Capital Markets, Janney Montgomery Scott LLC and Merriman Curhan Ford & Co. were listed as underwriters for the offering.

Description

Bioheart is using cells from a patient's own body to develop therapies for the treatment of heart diseases.


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Jun 18, 2007 MAP Pharmaceuticals, Inc. N/A $14-$16 N/A N/A N/A N/A

Lead Underwriter

Merrill Lynch & Co. and Morgan Stanley & Co. Incorporated are joint book-running managers for the offering. Deutsche Bank Securities Inc. is co-lead manager.

Description

MAP Pharmaceuticals is a product based biopharmaceutical company focused on developing novel treatments for respiratory and CNS diseases. MAP Pharmaceuticals' principal product development strategy is to create innovative therapies with large market potential to improve safety, efficacy, and patient compliance.


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Jun 11, 2007 Zars, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Cowen and Company and CIBC World Markets are joint book running managers for the offering. Leerink Swann & Company and Susquehanna Financial Group, LLLP are comanagers.

Description

ZARS, Inc. is a specialty pharmaceutical company focused on the development and commercialization of topically applied drugs using its proprietary drug delivery technologies, with an initial focus on pain management.


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Jun 5, 2007 Quark Pharmaceuticals QURK $12-$14 N/A N/A N/A N/A

Lead Underwriter

JPMorgan Chase and Bank of America.

Description

Quark is an evolving pharmaceutical company using rational drug design to develop new therapeutics for unmet medical needs.


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May 11, 2007 Targanta Therapeutics N/A N/A N/A $86.25M N/A N/A

Lead Underwriter

Credit Suisse, Cowen and Co., Lazard Capital Markets, and Leerink Swann & Co.

Description

The Cambridge, Massachusetts-based company, develops antibiotics for serious infections treated or acquired in hospitals.


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May 7, 2007 ImaRx Therapeutics N/A N/A N/A N/A N/A N/A

Lead Underwriter

Maxim Group, LLC

Description

ImaRx Therapeutics is a biopharmaceutical company developing and commercializing therapies for vascular disorders.


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May 2, 2007 Cumberland Pharmaceuticals Inc. CPIX N/A N/A $115M N/A N/A

Lead Underwriter

UBS Investment Bank, Jefferies & Company, Wachovia Securities and Morgan Joseph

Description

Cumberland Pharmaceuticals Inc. is a Tennessee-based specialty pharmaceutical company focused on the acquisition, development and commercialization of branded prescription products.


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Mar 21, 2007 Aegerion Pharmaceuticals, Inc. AEGR N/A N/A $86.25M N/A N/A

Lead Underwriter

Lehman Brothers Inc., CIBC World Markets Corp., Thomas Weisel Partners LLC, C.E. Unterberg, Towbin LLC are listed as the underwriters.

Description

Incorporated in February 2005 and headquartered in Bridgewater, New Jersey, Aegerion Pharmaceuticals is a specialty pharmaceutical company focusing on the development and commercialization of promising therapeutics to treat cardiovascular / metabolic disease.


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Mar 9, 2007 Jazz Pharmaceuticals, Inc. JAZZ N/A N/A $172.5M N/A N/A

Lead Underwriter

The offering is being made through Morgan Stanley, Lehman Brothers, Credit Suisse, and Natexis Bleichroeder.

Description

Jazz Pharmaceuticals is a specialty pharmaceutical company focused on identifying, developing and commercializing innovative products to meet unmet medical needs in neurology and psychiatry.


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Mar 1, 2007 Helicos BioSciences Corporation HLCS N/A N/A $100M N/A N/A

Lead Underwriter

UBS Investment Bank will be acting as the sole book-running manager for the offering. J.P. Morgan Securities Inc. is acting as a joint lead manager, with Leerink Swann & Company and Pacific Growth Equities, LLC acting as co-managers.

Description

Helicos BioSciences Corporation is a life sciences company developing innovative genetic analysis technologies for the research, drug discovery and clinical diagnostics markets.


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Mar 1, 2007 Sirtris Pharmaceuticals SIRT N/A N/A $60M N/A N/A

Lead Underwriter

J.P. Morgan Securities Inc. will serve as the sole book-running manager for the offering. CIBC World Markets Corp., Piper Jaffray & Co., JMP Securities LLC, and Rodman & Renshaw, LLC are acting as co-managers for the offering.

Description

Sirtris Pharmaceuticals is a biopharmaceutical company focused on discovering and developing proprietary, orally available, small molecule drugs with the potential to treat diseases associated with aging, including metabolic diseases such as Type 2 Diabetes.


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Feb 28, 2007 EndoCeutics ENCX N/A N/A $75M N/A N/A

Lead Underwriter

First Albany Capital, Oppenheimer & Co. and Stifel Nicolaus will underwrite the IPO.

Description

Canada's EndoCeutics Inc., a pharmaceutical firm developing hormone therapies for breast cancer and other endocrine-related disorders.


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Feb 27, 2007 Tongjitang Chinese Medicines Company N/A $15-$17 N/A N/A N/A N/A

Lead Underwriter

Merrill Lynch & Co. and UBS Investment Bank will act as joint global coordinators and joint book runners for the offering.

Description

Tongjitang Chinese Medicines Company, through its operating subsidiaries Tongjitang Pharmaceutical, Tongjitang Distribution, Tongjitang Chain Stores, and Tongjitang Planting, is a vertically integrated and profitable specialty pharmaceutical company focusing on the development, manufacturing, marketing and selling of modernized traditional Chinese medicine in China.


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Feb 14, 2007 Bioheart, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

BMO Capital Markets Corp. will act as sole book-running manager of the proposed offering. Janney Montgomery Scott, LLC and Merriman Curhan Ford & Co. will act as co-lead manager and co-manager of the proposed offering, respectively.

Description

Bioheart, Inc. is a biotechnology company focused on the discovery, development and commercialization of therapies using cells derived from a patient's body, and related devices, for the treatment of heart damage.


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Feb 7, 2007 Biodel Inc. N/A N/A N/A $86.25M N/A N/A

Lead Underwriter

Banc of America Securities LLC and CIBC World Markets are leading the deal's underwriting.

Description

Biodel Inc. is a specialty pharmaceutical company that develops novel formulations of already approved therapeutics to treat endocrine disorders such as diabetes and osteoporosis.


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Feb 7, 2007 NeurogesX, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Morgan Stanley & Co. Incorporated will act as the sole book runner and lead manager for the offering. In addition, Pacific Growth Equities, LLC, Lazard Capital Markets LLC and Susquehanna Financial Group, LLLP will act as co-managers of the offering.

Description

NeurogesX is a biopharmaceutical company based in the San Francisco Bay Area. Our focus is on the development of effective treatments that relieve chronic pain and improve quality of life.


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Jan 19, 2007 3SBio N/A N/A N/A $7.7M N/A N/A

Lead Underwriter

N/A

Description

3SBio Inc. is a leading, fully integrated biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, primarily in China.


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Dec 19, 2006 Orexigen Therapeutics, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Merrill Lynch & Company is acting as sole book-running manager and J.P. Morgan Securities Inc. is co-lead manager, with JMP Securities LLC and Leerink Swann & Company acting as co-managers for the offering.

Description

Orexigen(TM) Therapeutics, Inc. is a biopharmaceutical company focused on the development and commercialization of pharmaceutical products for the treatment of central nervous system disorders, with an initial focus on obesity.


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Dec 13, 2006 OncoGenex Technologies Inc. N/A N/A N/A $48M N/A N/A

Lead Underwriter

RBC Capital Markets will be the sole lead manager for the Offering, and the co-managers will be Needham & Company, LLC, Lazard Capital Markets LLC, Canaccord Adams Inc. and Susquehanna Financial Group, LLLP.

Description

OncoGenex is committed to the development and commercialization of new cancer therapies that address treatment resistance in cancer patients.


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Nov 22, 2006 Synta Pharmaceuticals N/A N/A N/A $115M N/A N/A

Lead Underwriter

Bear, Stearns & Co. Inc. and Lehman Brothers Inc. are acting as joint book-running managers and Lazard Capital Markets LLC and Montgomery & Co., LLC are acting as co-managers for the offering.

Description

Synta Pharmaceuticals Corp. is a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to extend and enhance the lives of patients with severe medical conditions, including cancer and chronic inflammatory diseases.


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Nov 14, 2006 Accuray Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

J.P. Morgan Securities Inc. and UBS Investment Bank will be acting as joint bookrunning managers, with Piper Jaffray & Co. as lead manager and Jefferies & Company, Inc. as co-manager for the offering.

Description

Accuray designs, develops and sells the CyberKnife® System, an image- guided robotic radiosurgery system used for the treatment of solid tumors anywhere in the body.


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Nov 10, 2006 Optimer Pharmaceuticals, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Piper Jaffray & Co. and Jefferies & Company, Inc. are acting as joint book-running managers. JMP Securities LLC and Rodman & Renshaw, LLC are acting as co-managers for the offering.

Description

Optimer Pharmaceuticals is a biopharmaceutical company focused on discovering, developing and commercializing innovative anti-infective products for the treatment of serious infections.


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Sep 21, 2006 St. Francis Medical Technologies N/A N/A N/A $86.25M N/A N/A

Lead Underwriter

Citigroup Global Markets Inc. and J.P. Morgan Securities Inc. will be acting as joint bookrunning managers and Piper Jaffray & Co. and Thomas Weisel Partners LLC will be acting as co-managers.

Description

St. Francis Medical is a medical device company focused on the design, development and marketing of motion-preserving technologies and procedures for orthopedic and neurological spine surgery.


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Sep 13, 2006 Obagi Medical Products, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

JPMorgan, CIBC World Markets, Thomas Weisel Partners LLC and Robert W. Baird & Co.

Description

Obagi Medical Products is located in Long Beach, California.


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Sep 7, 2006 Rosetta Genomics Ltd. ROSG $11-$13 N/A $39M N/A N/A

Lead Underwriter

C.E. Unterberg Towbin LLC is the lead manager and sole bookrunner, and Oppenheimer & Co. Inc. and Maxim Group LLC are co-managers.

Description

Rosetta Genomics is focused on developing diagnostic and therapeutic products for cancers and infectious diseases.


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Aug 16, 2006 Acologix, Inc. N/A N/A N/A $115M N/A N/A

Lead Underwriter

N/A

Description

Acologix is a California-based biopharma firm developing drugs to treat renal diseases, including diseases related to hard tissues, such as bone, teeth and cartilage, as well as the kidney and associated organs.


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Aug 16, 2006 Hansen Medical HNSN N/A N/A $86M N/A N/A

Lead Underwriter

The underwriters of the offering will be Morgan Stanley & Co. Incorporated and JP Morgan Securities Inc. as joint bookrunners and co-lead managers, and Thomas Weisel Partners LLC and Leerink Swann & Co., Inc. as co-managers.

Description

Hansen Medical Inc. is a medical robotics company.


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Aug 15, 2006 Emergent BioSolutions EBSI N/A N/A $86M N/A N/A

Lead Underwriter

J.P. Morgan Securities Inc. will serve as sole book-running manager for the offering. Cowen and Company, LLC will be the joint lead manager, and HSBC Securities (USA) Inc. will be the co-manager for the offering.

Description

Emergent BioSolutions is a biopharmaceutical company focused on the development, manufacture and commercialization of immunobiotics.


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Aug 14, 2006 ActivBiotics N/A N/A N/A N/A N/A N/A

Lead Underwriter

HSBC Securities (USA) Inc. will be acting as the book-running manager and Needham & Company, LLC, BMO Capital Markets Corp. and Susquehanna Financial Group, LLLP will be acting as co-managers in this offering.

Description

ActivBiotics, Inc. is a biopharmaceutical company focused on the discovery, development and commercialization of therapies for the treatment of inflammatory diseases and bacterial infections.


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Aug 11, 2006 Virtual Radiologic N/A N/A N/A N/A N/A N/A

Lead Underwriter

Goldman, Sachs & Co. will act as the sole book-runner and co-lead manager, Merrill Lynch & Co. will act as co-lead manager and William Blair & Company will act as the co-manager for the proposed offering.

Description

Virtual Radiologic Corporation is a provider of remote diagnostic image interpretation, or teleradiology, services.


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Aug 11, 2006 Thermage, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Merrill Lynch, Pierce, Fenner & Smith Incorporated will act as the sole bookrunning manager for the offering. In addition, Thomas Weisel Partners LLC, Wachovia Capital Markets, LLC, C.E. Unterberg, Towbin, LLC and Maxim Group LLC will act as co-managers of the offering.

Description

Thermage, Inc. is a leading medical device company that manufactures and markets non-invasive treatments to tighten and contour skin


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Aug 8, 2006 Xtent Inc. XTNT N/A N/A $103.5M N/A N/A

Lead Underwriter

Piper Jaffray & Co. will be acting as the book-running manager and Cowen and Company LLC, Lazard Capital Markets LLC, and RBC Capital Markets are acting as co-managers.

Description

XTENT is a medical device company focused on the development and commercialization of innovative customizable drug eluting stent systems for the treatment of coronary and peripheral artery disease.


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July 31, 2006 Affymax, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

The underwriters of the offering will be Morgan Stanley & Co. Incorporated as sole book runner and co-lead manager, Cowen and Company, LLC and Thomas Weisel Partners LLC as co-lead managers, and RBC Capital Markets as co- manager.

Description

Affymax, Inc. is a clinical-stage biopharmaceutical company creating novel peptide-based drugs to improve the treatment of serious and often life- threatening conditions.


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July 24, 2006 Asthmatx, Inc. AZMA N/A N/A $75M N/A N/A

Lead Underwriter

Piper Jaffray and Bear, Stearns & Co.

Description

Asthmatx, Inc. is focused on helping patients with asthma breathe easier.


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July 19, 2006 Innophos Holdings, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Credit Suisse Securities (USA), LLC, Bear, Stearns & Co. Inc. and UBS Investment Bank will be acting as joint book-running managers.

Description

Innophos, Inc. (http://www.innophos.com ) is one of the leading North American manufacturers of specialty phosphates, serving a diverse range of customers across multiple applications, geographies and channels.


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July 17, 2006 Cadence Pharmaceuticals, Inc. N/A N/A N/A $86.3M N/A N/A

Lead Underwriter

Merrill Lynch & Co. is acting as sole book-running manager and Deutsche Bank Securities Inc. is acting as co-lead manager for the offering. In addition, Pacific Growth Equities, LLC and JMP Securities LLC will be acting as co-managers for the offering.

Description

Cadence Pharmaceuticals is a biopharmaceutical company focused on in-licensing, developing and commercializing proprietary product candidates principally for use in the hospital setting.


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July 17, 2006 Metabolix, Inc. N/A N/A N/A N/A N/A N/A

Lead Underwriter

Piper Jaffray & Co. will be the sole book-running manager for the offering. Jefferies & Company, Inc., Thomas Weisel Partners LLC and Ardour Capital Investments, LLC will be co-managers for the offering.

Description

Metabolix is a biotechnology company that develops and plans to commercialize environmentally sustainable, economically attractive alternatives to petrochemical-based plastics, fuels and chemicals.


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July 5, 2006 Applied Precision, Inc. APLI N/A N/A $57.5M N/A N/A

Lead Underwriter

CIBC World Markets, Cowen and Company and Canaccord Adams

Description

Applied Precision Inc.provides tools for the semiconductor and life sciences industries.


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July 3, 2006 Oculus Innovative Sciences OCLS N/A N/A $80.5M N/A N/A

Lead Underwriter

A.G. Edwards, Jefferies & Company, First Albany Capital and C.E. Unterberg Towbin

Description

Oculus Innovative Sciences Inc. makes products to help prevent and eliminate infection in chronic and acute wounds.
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