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PLoS By Category | Recent PLoS Articles
Chemical Biology
 
The Dynamics of Ca2+ Ions within the Solvation Shell of Calbindin D9k  Tuesday, February 22, 2011
Zebrafish Bioassay-Guided Natural Product Discovery: Isolation of Angiogenesis Inhibitors from East African Medicinal Plants  Thursday, February 17, 2011
Differential Neuroprotective Activity of Two Different Grape Seed Extracts  Monday, January 24, 2011
Safety and Feasibility of Long-term Intravenous Sodium Nitrite Infusion in Healthy Volunteers  Monday, January 10, 2011
An Exploration on Greenhouse Gas and Ammonia Production by Insect Species Suitable for Animal or Human Consumption  Wednesday, December 29, 2010
Niclosamide Prevents the Formation of Large Ubiquitin-Containing Aggregates Caused by Proteasome Inhibition  Thursday, December 23, 2010
Grifonin-1: A Small HIV-1 Entry Inhibitor Derived from the Algal Lectin, Griffithsin  Thursday, December 16, 2010
Nuclear Shield: A Multi-Enzyme Task-Force for Nucleus Protection  Friday, December 10, 2010
Phenocopy – A Strategy to Qualify Chemical Compounds during Hit-to-Lead and/or Lead Optimization  Friday, December 10, 2010
Protein Markers for Insulin-Producing Beta Cells with Higher Glucose Sensitivity  Monday, December 06, 2010
Activation of Protein Serine/Threonine Phosphatase PP2Ca Efficiently Prevents Liver Fibrosis  Monday, December 06, 2010
Reversal of Obesity and Insulin Resistance by a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist in Diet-Induced Obese Mice  Friday, December 03, 2010
Expression and Regulation of Cyclic Nucleotide Phosphodiesterases in Human and Rat Pancreatic Islets  Wednesday, December 01, 2010
Molecular Characterization of c-Abl/c-Src Kinase Inhibitors Targeted against Murine Tumour Progenitor Cells that Express Stem Cell Markers  Tuesday, November 30, 2010
Homodimerization of the Death-Associated Protein Kinase Catalytic Domain: Development of a New Small Molecule Fluorescent Reporter  Tuesday, November 30, 2010
Cucurbitacin I Inhibits Cell Motility by Indirectly Interfering with Actin Dynamics  Wednesday, November 24, 2010
Essential Role for the d-Asb11 cul5 Box Domain for Proper Notch Signaling and Neural Cell Fate Decisions In Vivo  Friday, November 19, 2010
Photounbinding of Calmodulin from a Family of CaM Binding Peptides  Thursday, November 18, 2010
Metallothioneins Are Required for Formation of Cross-Adaptation Response to Neurobehavioral Toxicity from Lead and Mercury Exposure in Nematodes  Thursday, November 18, 2010
Characterisation of PduS, the pdu Metabolosome Corrin Reductase, and Evidence of Substructural Organisation within the Bacterial Microcompartment  Tuesday, November 16, 2010
Gene Expression in the Scleractinian Acropora microphthalma Exposed to High Solar Irradiance Reveals Elements of Photoprotection and Coral Bleaching  Friday, November 12, 2010
Characterization of Engineered Actin Binding Proteins That Control Filament Assembly and Structure  Friday, November 12, 2010
Localization of Secondary Metabolites in Marine Invertebrates: Contribution of MALDI MSI for the Study of Saponins in Cuvierian Tubules of H. forskali  Wednesday, November 10, 2010
Static Magnetic Field Exposure Reproduces Cellular Effects of the Parkinson's Disease Drug Candidate ZM241385  Monday, November 08, 2010
An Essential Difference between the Flavonoids MonoHER and Quercetin in Their Interplay with the Endogenous Antioxidant Network  Monday, November 08, 2010
Differential Volatile Signatures from Skin, Naevi and Melanoma: A Novel Approach to Detect a Pathological Process  Thursday, November 04, 2010
High-Affinity Inhibitors of Human NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships  Tuesday, November 02, 2010
Profiling Y561-Dependent and -Independent Substrates of CSF-1R in Epithelial Cells  Tuesday, October 26, 2010
Differential Protein Expression in Honeybee (Apis mellifera L.) Larvae: Underlying Caste Differentiation  Wednesday, October 20, 2010
Context-Dependent Cell Cycle Checkpoint Abrogation by a Novel Kinase Inhibitor  Monday, October 18, 2010
Uniform Silica Coated Fluorescent Nanoparticles: Synthetic Method, Improved Light Stability and Application to Visualize Lymph Network Tracer  Monday, October 18, 2010
Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture  Friday, January 27, 2012
Plastic and Heritable Components of Phenotypic Variation in Nucella lapillus: An Assessment Using Reciprocal Transplant and Common Garden Experiments  Friday, January 27, 2012
Interactive Effects of Large- and Small-Scale Sources of Feral Honey-Bees for Sunflower in the Argentine Pampas  Friday, January 27, 2012
Consistent Pattern of Local Adaptation during an Experimental Heat Wave in a Pipefish-Trematode Host-Parasite System  Friday, January 27, 2012
Synergistic TLR2/6 and TLR9 Activation Protects Mice against Lethal Influenza Pneumonia  Friday, January 27, 2012
Induction of Heterosubtypic Cross-Protection against Influenza by a Whole Inactivated Virus Vaccine: The Role of Viral Membrane Fusion Activity  Friday, January 27, 2012
Immunohistochemical Profile for Unknown Primary Adenocarcinoma  Friday, January 27, 2012
Antibody to P. falciparum in Pregnancy Varies with Intermittent Preventive Treatment Regime and Bed Net Use  Friday, January 27, 2012
Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models  Friday, January 27, 2012
Interventions to Influence Consulting and Antibiotic Use for Acute Respiratory Tract Infections in Children: A Systematic Review and Meta-Analysis  Friday, January 27, 2012
A Piezoelectric Immunosensor Using Hybrid Self-Assembled Monolayers for Detection of Schistosoma japonicum  Friday, January 27, 2012
Patient's Origin and Lifestyle Associated with CTX-M-Producing Escherichia coli: A Case-Control-Control Study  Friday, January 27, 2012
A Bovine Model of Respiratory Chlamydia psittaci Infection: Challenge Dose Titration  Friday, January 27, 2012
Does a Family Meetings Intervention Prevent Depression and Anxiety in Family Caregivers of Dementia Patients? A Randomized Trial  Friday, January 27, 2012
LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth  Friday, January 27, 2012
MIR-99a and MIR-99b Modulate TGF-ß Induced Epithelial to Mesenchymal Plasticity in Normal Murine Mammary Gland Cells  Friday, January 27, 2012
Reorganizing the Intrinsic Functional Architecture of the Human Primary Motor Cortex during Rest with Non-Invasive Cortical Stimulation  Friday, January 27, 2012
The Cost of Universal Health Care in India: A Model Based Estimate  Friday, January 27, 2012
Myocardial Alternative RNA Splicing and Gene Expression Profiling in Early Stage Hypoplastic Left Heart Syndrome  Friday, January 27, 2012
ERK1 Regulates the Hematopoietic Stem Cell Niches  Monday, January 30, 2012
Simulated Warming Differentially Affects the Growth and Competitive Ability of Centaurea maculosa Populations from Home and Introduced Ranges  Monday, January 30, 2012
Seeing Emotion with Your Ears: Emotional Prosody Implicitly Guides Visual Attention to Faces  Monday, January 30, 2012
CCL2 Is Associated with a Faster Rate of Cognitive Decline during Early Stages of Alzheimer's Disease  Monday, January 30, 2012
Quality Control and Performance of HIV Rapid Tests in a Microbicide Clinical Trial in Rural KwaZulu-Natal  Monday, January 30, 2012
Automated Workflow for Preparation of cDNA for Cap Analysis of Gene Expression on a Single Molecule Sequencer  Monday, January 30, 2012
TBX21 and HLX1 Polymorphisms Influence Cytokine Secretion at Birth  Monday, January 30, 2012
Metabolic Profiles and cDNA-AFLP Analysis of Salvia miltiorrhiza and Salvia castanea Diel f. tomentosa Stib  Monday, January 30, 2012
An Ensemble Classifier for Eukaryotic Protein Subcellular Location Prediction Using Gene Ontology Categories and Amino Acid Hydrophobicity  Monday, January 30, 2012
Catalog of MicroRNA Seed Polymorphisms in Vertebrates  Friday, January 27, 2012
Access to Barrier Perches Improves Behavior Repertoire in Broilers  Friday, January 27, 2012
Predicting Target DNA Sequences of DNA-Binding Proteins Based on Unbound Structures  Wednesday, February 01, 2012
Environmentally Realistic Exposure to the Herbicide Atrazine Alters Some Sexually Selected Traits in Male Guppies  Wednesday, February 01, 2012
Conditional Ablation of Ezh2 in Murine Hearts Reveals Its Essential Roles in Endocardial Cushion Formation, Cardiomyocyte Proliferation and Survival  Wednesday, February 01, 2012
Responsiveness to 6-n-Propylthiouracil (PROP) Is Associated with Salivary Levels of Two Specific Basic Proline-Rich Proteins in Humans  Wednesday, February 01, 2012
Viremic HIV Infected Individuals with High CD4 T Cells and Functional Envelope Proteins Show Anti-gp41 Antibodies with Unique Specificity and Function  Wednesday, February 01, 2012
Implications of Extreme Life Span in Clonal Organisms: Millenary Clones in Meadows of the Threatened Seagrass Posidonia oceanica  Wednesday, February 01, 2012
Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families  Wednesday, February 01, 2012
In Silico Insights into the Symbiotic Nitrogen Fixation in Sinorhizobium meliloti via Metabolic Reconstruction  Wednesday, February 01, 2012
Defining Plasmodium falciparum Treatment in South West Asia: A Randomized Trial Comparing Artesunate or Primaquine Combined with Chloroquine or SP  Tuesday, January 31, 2012
Early Cell Death Detection with Digital Holographic Microscopy  Tuesday, January 31, 2012
A Role for VEGFR2 Activation in Endothelial Responses Caused by Barrier Disruptive OxPAPC Concentrations  Tuesday, January 31, 2012
A New Eusuchian Crocodyliform with Novel Cranial Integument and Its Significance for the Origin and Evolution of Crocodylia  Tuesday, January 31, 2012
Increased Inter-Colony Fusion Rates Are Associated with Reduced COI Haplotype Diversity in an Invasive Colonial Ascidian Didemnum vexillum  Tuesday, January 31, 2012
Ologs: A Categorical Framework for Knowledge Representation  Tuesday, January 31, 2012
Primary Xenografts of Human Prostate Tissue as a Model to Study Angiogenesis Induced by Reactive Stroma  Tuesday, January 31, 2012
Novel, Objective, Multivariate Biomarkers Composed of Plasma Amino Acid Profiles for the Diagnosis and Assessment of Inflammatory Bowel Disease  Tuesday, January 31, 2012
Increased GABAA Receptor e-Subunit Expression on Ventral Respiratory Column Neurons Protects Breathing during Pregnancy  Tuesday, January 31, 2012
Boolean Models of Biosurfactants Production in Pseudomonas fluorescens  Tuesday, January 31, 2012
Homology Inference of Protein-Protein Interactions via Conserved Binding Sites  Tuesday, January 31, 2012
The Risk of Stroke after Percutaneous Vertebroplasty for Osteoporosis: A Population-Based Cohort Study  Tuesday, January 31, 2012
Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types  Wednesday, February 01, 2012
Polyglutamine Repeats Are Associated to Specific Sequence Biases That Are Conserved among Eukaryotes  Wednesday, February 01, 2012
Season of Sampling and Season of Birth Influence Serotonin Metabolite Levels in Human Cerebrospinal Fluid  Wednesday, February 01, 2012
Eradication of Metastatic Renal Cell Carcinoma after Adenovirus-Encoded TNF-Related Apoptosis-Inducing Ligand (TRAIL)/CpG Immunotherapy  Wednesday, February 01, 2012
Two-Item Sentence Comprehension by a Dog (Canis familiaris)  Wednesday, February 01, 2012
Tobacco Rattle Virus Vector: A Rapid and Transient Means of Silencing Manduca sexta Genes by Plant Mediated RNA Interference  Wednesday, February 01, 2012
Mitogen- and Stress-Activated Kinase 1 (MSK1) Regulates Cigarette Smoke-Induced Histone Modifications on NF-?B-dependent Genes  Wednesday, February 01, 2012
Genetic Association Analysis Using Sibship Data: A Multilevel Model Approach  Wednesday, February 01, 2012
Helicobacter pylori CagA Triggers Expression of the Bactericidal Lectin REG3? via Gastric STAT3 Activation  Wednesday, February 01, 2012
Mimicry of Food Intake: The Dynamic Interplay between Eating Companions  Wednesday, February 01, 2012
Innate Sex Differences in the Timing of Spring Migration in a Songbird  Wednesday, February 01, 2012
Sleep Disorders and Demand for Medical Services: Evidence from a Population-Based Longitudinal Study  Wednesday, February 01, 2012
Potent Phototoxicity of Marine Bunker Oil to Translucent Herring Embryos after Prolonged Weathering  Wednesday, February 01, 2012
From Food to Offspring Down: Tissue-Specific Discrimination and Turn-Over of Stable Isotopes in Herbivorous Waterbirds and Other Avian Foraging Guilds  Wednesday, February 01, 2012
Trans-Synaptic Spread of Tau Pathology In Vivo  Wednesday, February 01, 2012
Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling  Wednesday, February 01, 2012
NGS QC Toolkit: A Toolkit for Quality Control of Next Generation Sequencing Data  Wednesday, February 01, 2012
Murine GRPR and Stathmin Control in Opposite Directions both Cued Fear Extinction and Neural Activities of the Amygdala and Prefrontal Cortex  Wednesday, February 01, 2012
S-LOCUS EARLY FLOWERING 3 Is Exclusively Present in the Genomes of Short-Styled Buckwheat Plants that Exhibit Heteromorphic Self-Incompatibility  Wednesday, February 01, 2012
Measuring the Impacts of Community-based Grasslands Management in Mongolia's Gobi  Wednesday, February 01, 2012
Knowledge-Based Reconstruction of mRNA Transcripts with Short Sequencing Reads for Transcriptome Research  Wednesday, February 01, 2012
CenSeam, an International Program on Seamounts within the Census of Marine Life: Achievements and Lessons Learned  Wednesday, February 01, 2012
Inhibition of Wnt/ß-Catenin Signaling by a Soluble Collagen-Derived Frizzled Domain Interacting with Wnt3a and the Receptors Frizzled 1 and 8  Friday, January 27, 2012
ISL1 Directly Regulates FGF10 Transcription during Human Cardiac Outflow Formation  Friday, January 27, 2012
Differential Role of PKC-Induced c-Jun in HTLV-1 LTR Activation by 12-O-Tetradecanoylphorbol-13-acetate in Different Human T-cell Lines  Friday, January 27, 2012
Busulphan-Cyclophosphamide Cause Endothelial Injury, Remodeling of Resistance Arteries and Enhanced Expression of Endothelial Nitric Oxide Synthase  Friday, January 27, 2012
Non-Host Defense Response in a Novel Arabidopsis-Xanthomonas citri subsp. citri Pathosystem  Friday, January 27, 2012