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PLoS By Category | Recent PLoS Articles
Gastroenterology and Hepatology - Radiology and Medical Imaging - Surgery

Percutaneous Transhepatic Balloon Dilation of Biliary-Enteric Anastomotic Strictures after Surgical Repair of Iatrogenic Bile Duct Injuries
Published: Friday, October 26, 2012
Author: Andrew Y. Lee et al.

by Andrew Y. Lee, John Gregorius, Robert K. Kerlan, Roy L. Gordon, Nicholas Fidelman


To evaluate the efficacy of percutaneous balloon dilation of biliary-enteric anastomotic strictures resulting from surgical repair of laparoscopic cholecystectomy-related bile duct injuries.

Material and Methods

A total of 61 patients were referred to our institution from 1995 to 2010 for treatment of obstruction at the biliary-enteric anastomosis following surgical repair of laparoscopic cholecystectomy-related bile duct injuries. Of these 61 patients, 27 underwent surgical revision upon stricture diagnosis, and 34 patients were managed using balloon dilation. Of these 34 patients, 2 were lost to follow up, leaving 32 patients for analysis. The primary study objective was to determine the clinical success rate of balloon dilation of biliary-enteric anastomotic strictures. Secondary study objectives included determining anastomosis patency, rates of stricture recurrence following treatment, and morbidity.


Balloon dilation of biliary-enteric anastomotic strictures was clinically successful in 21 of 32 patients (66%). Anastomotic stricture recurred in one of 21 patients (5%) after an average of 13.1 years of follow-up. Patients who were unsuccessfully managed with balloon dilation required significantly more invasive procedures (6.8 v. 3.4; p?=?0.02) and were left with an indwelling biliary catheter for a significantly longer period of time (8.8 v. 2.0 months; p?=?0.02) than patients whose strictures could be resolved by balloon dilation. No significant differences in the number of balloon dilations performed (p?=?0.17) or in the maximum balloon diameter used (p?=?0.99) were demonstrated for patients with successful or unsuccessful balloon dilation outcomes.


Percutaneous balloon dilation of anastomotic biliary strictures following surgical repair of laparoscopic cholecystectomy-related injuries may result in lasting patency of the biliary-enteric anastomosis.