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PLoS By Category | Recent PLoS Articles
Critical Care and Emergency Medicine - Surgery

Hypertensive Patients Show Delayed Wound Healing following Total Hip Arthroplasty
Published: Thursday, August 11, 2011
Author: Awad A. Ahmed et al.

by Awad A. Ahmed, Pekka A. Mooar, Matthew Kleiner, Joseph S. Torg, Curtis T. Miyamoto

Background

Prolonged wound-discharge following total hip arthroplasty (THA) is associated with an increased risk of infection. However, the potential role of hypertension in prolonging the duration of wound healing in this population has not yet been investigated. The aim of the present study was to compare healing in this population that has not yet been investigated. The aim of the present study was to compare hypertensive and normotensive THA patients in terms of the length of time required to achieve a dry wound and the length of stay in the hospital.

Methods

One hundred and twenty primary THA patients were evaluated. Pre-operative clinical history and physical examination revealed that 29 were hypertensive and 91 were normotensive. The two groups were statistically matched using optimal propensity score matching. The outcomes of interest were the number of days until a dry wound was observed and the duration of hospital stay.

Results

The average systolic blood pressures were 150.1 mmHg and 120.3 mmHg for the hypertensive and normotensive groups, respectively. The mean number of days until the wound was dry was 3.79 for the hypertensive group and 2.03 for the normotensive group. Hypertensive patients required more days for their wounds to dry than normotensive patients (odds ratio ?=?1.65, p<0.05). No significant difference in the duration of hospital stay was found between the two groups.

Conclusions

Hypertensive patients had a higher risk of prolonged wound discharge after THA than their normotensive counterparts. Patients with prolonged wound drainage are at greater risk for infection. Clinicians should pay particular attention to infection-prevention strategies in hypertensive THA patients.

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