BioSpace Collaborative

Academic/Biomedical Research
News & Jobs
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  C2C Services & Suppliers™
Europe
Asia

DIVERSITY

PROFILES
Company Profiles

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Research Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
Get Our Industry eNewsletter FREE email:    
   

TransMedics, Inc. Release: the OCS™ Lung Initial European Clinical Experience Featured in the Lancet


10/10/2012 11:14:33 AM

ANDOVER, Mass., Oct. 10, 2012 /PRNewswire/ -- TheLancet has published the initial series of successful lung transplants demonstrating the feasibility and safety of using the Organ Care System (OCS) Lung technology, at Hannover Medical School and Puerta de Hierro Hospital Madrid.

(Photo: http://photos.prnewswire.com/prnh/20121010/NE90070 )

A study published in the October 10th edition of The Lancet reports on the first in-man clinical experience with the OCS Lung technology. These cases were conducted in two leading lung transplant centers in Germany and Spain. Representing a full spectrum of donor and recipient risk factors/indications for lung transplantation, these cases evaluate the feasibility and safety of the OCS technology. All lungs were successfully preserved on the OCS system and transplanted with excellent results. This study was the foundation to initiate the ongoing international prospective randomized INSPIRE Trial to evaluate the effectiveness of the OCS Lung device.

"Our early clinical data supports the use of the OCS Lung. We show good outcomes of lung transplantation following preservation on OCS Lung in a high-risk recipient population," said Dr. Gregor Warnecke at the Hannover Medical School in Germany. "The full potential of this technology will be exemplified in the data resulting from the ongoing INSPIRE Trial and we are enthusiastic to move this important trial forward."

"We are excited by The Lancet publication and we look forward to continuing our global collaboration with leading lung transplant centers to complete and report the results from the INSPIRE Trial," said Dr. Waleed Hassanein, President and CEO of TransMedics, Inc.

INSPIRE is an international, multi-center, large clinical trial that is randomizing subjects. It will evaluate the success of lung preservation using OCS technology as compared to traditional cold-storage preservation. The INSPIRE Trial is approved under the US Food & Drug Administration for an investigational device exemption (IDE), and it is currently enrolling patients in leading lung transplant centers in Europe, US, Australia, and Canada. For more information about the INSPIRE Trial, visit www.inspireclinicaltrial.com.

About OCS
Since the advent of transplantation, the cornerstone of organ preservation has been cold ischemic storage (organs on ice). Although this method is intended to help reduce the extent of organ damage during transport, significant damage still occurs. The longer an organ is stored this way, the more damage occurs. Moreover, the cold-storage technique does not enable any optimization or monitoring capabilities during transportation from donor to recipient. It is estimated that only 15-20% of donor lungs are utilized for transplantation globally based on the limitations of cold storage.

TransMedics has developed the world's only portable medical device capable of overcoming the above limitations of cold storage for organ transplantation. OCS technology was designed to provide a comprehensive solution to all three key limitations of the cold storage technique.

OCS Lung:

  • Minimizes cold ischemia injury by perfusing the organs with a proprietary warm perfusate
  • Optimizes the condition of organs by replenishing oxygen, nutrients and hormones that are depleted
  • Provides continuous monitoring and assessment capabilities for the organs until the point of transplantation

About TransMedics, Inc.
TransMedics is a privately held medical technology company dedicated to extending the life saving benefits of organ transplantation to patients suffering from end-stage organ failure. Headquartered in Andover, Massachusetts, the company was founded in 1998 to address the unmet need for more and better organs for transplants. For more information, please visit www.TransMedics.com.

SOURCE TransMedics, Inc.


Read at BioSpace.com


   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES
 

//-->