Leiden, Netherlands/Oxford, United Kingdom, March 7, 2013 / B3C newswire / – Dutch biotech company ProteoNic BV and Oxford Expression Technologies Ltd (OET), a leading provider of baculovirus-based protein expression products and services, have extended their partnership by signing a commercial license agreement. OET obtains the right to use ProteoNic’s UNic™ translation enhancing elements in its flashBAC™ system for third party recombinant protein production services. ProteoNic will provide technical support. Financial terms include upfront and royalty payments.
Both companies will be represented at BIO Europe Spring in Barcelona on March 11 -13 and are available for partnering meetings.
Under a previous collaboration, the two companies have successfully combined ProteoNic’s award-winning UNic™ translation enhancing technology with OET’s flashBAC™ system to significantly enhance recombinant protein yields in insect cells. Application of UNic™ not only allows increased overall efficiency and reduction of costs, but also facilitates (pre)clinical development of biopharmaceutical products that otherwise might be discarded due to difficulties in achieving acceptable production levels. This allows biopharmaceutical companies to broaden their pipeline and increase its value while reducing the drug development risk profile. From now on OET’s contract manufacturing services will include UNic™ technology.
Rory Woodhouse, Sales Manager at OET commented: “The combination of the unique UNic™ technology and the flashBAC™ expression system has already proved itself to have a positive effect on eukaryotic protein expression. This new agreement will enable us to build on our partnership and experience with ProteoNic, working together to provide a superior platform for our customers with more challenging to express proteins.”
Victor Schut, Chief Business Officer at ProteoNic added: “We are pleased to have demonstrated the value of partnership in combining two proven technologies. This will allow our customers to benefit from both our expertise through only one service. The successful application of our technology in the flashBAC system adds another recombinant protein production platform to our portfolio enabling us to serve a new market for ProteoNic.”
About Oxford Expression Technologies
Oxford Expression Technologies is a biotechnology company and centre of excellence for baculovirus protein expression. Specializing in the use of the baculovirus expression vector system, a eukaryotic expression system that can express a large variety of recombinant proteins, Oxford Expression Technologies provides protein expression products, services and consultancy to clients worldwide. The Company’s proprietary flashBAC™ technology enables large amounts of a given protein to be produced in culture. Its internationally renowned expertise and products enable proteins to be produced faster, more easily and cost-effectively using automated and high-throughput methods compared with other baculovirus systems. This contributes to the development of new drugs and research targeted towards understanding how proteins work in health and disease.
ProteoNic offers cell line generation and other products and services for improving recombinant protein expression in pharmaceutical production platforms. Its proprietary UNic™ technology enhances the translation of messenger RNA (mRNA) and so produces more protein per mRNA. This delivers significantly higher yields and greater manufacturing flexibility with lower production costs. The company’s activities focus on industry-relevant mammalian, yeast and insect cell expression hosts, for which it has developed platform-specific products and services. ProteoNic is the winner of the 2010 Frost & Sullivan Innovative Technology Award.
For more information contact:
Victor Schut, CBO
+31 71 523 1951
Oxford Expression Technologies
+44 1865 484175