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Advanced Biotechnologies Inc. Adds Cytomegalovirus (CMV) ß-PL Inactivated Purified Whole Virus Product


5/28/2009 2:39:50 PM

Columbia, MD - May 2009 Cytomegalovirus (CMV) AD169, Purified Whole Virus was inactivated by treatment with Beta-propiolactone (ß-PL). ß-PL is a DNA alkylating agent that has been shown to be effective in the inactivation of a virus. It chemically modifes viral DNA without affecting the immunogenicity or protein structure. After treatment with ß-PL, infectious CMV was completely inactivated as validated by cell culture based assay, but retained viral morphology (by TEM). Catalog # 10-275-500

CMV is a common virus that shows no discrimination for geographic or socioeconomic groups. It is a latent virus found in about 50% to 80% of adults but when the immune system is compromised by infectious disease or cancer it can cause illness and death. It has also been linked to many congenital birth defects such as Down syndrome, fetal alcohol syndrome, and neural tube defects.

Advanced Biotechnologies Inc. (ABI) www.abionline.com is a privately held biotechnology company specializing in the development, manufacture, and supply of critical products and services for the research and monitoring of infectious disease. ABI has been a integral partner for over 27 years to Pharmaceutical, Laboratories, Diagnostic and Research companies by using unparalleled manufacturing techniques to produce large-scale in vitro virology products and services.


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