|Event Name||2016 41th Symposium on Hormones and Cell Regulation
Wednesday, October 05, 2016
Saturday, October 08, 2016
Mont Ste Odile
|Description||This symposium has now been taking place for over 40 years. All along, organizers have paid attention to invite top of the line investigators in the fields presented. The pleasant and relaxed setting of the venue - a monastery 30 km from Strasbourg - encourages exchange of scientific knowledge between all participants. The audience is limited to around 100 people from academic and industry research, including postdoctoral fellows and students. This gives everybody the opportunity to meet and discuss their science with experts in the field and fosters scientific interactions. Participants are encouraged to present posters, and a small number of outstanding posters will be presented in oral sessions. In addition, a poster prize will be awarded.
Topics of the Symposium :
This meeting covers various aspects of the biology of G-protein-coupled receptors (GPCRs) and their signalling pathways. A special focus will be on new data and concepts concerning the structure and function of GPCRs, novel ways to control and to use this receptor class and on GPCRs in metabolism and other emerging fields relevant for pathophysiology and therapy.
GPCRs are the direct targets of a third of the pharmaceutical drugs presently on sale. They are involved in many clinical disorders including cardiovascular, endocrine, metabolic and neurological diseases, and they are still regarded as a prime source for the development of new drugs.
At this meeting, the most recent aspects of the research in the field will be presented by speakers of international reputation. Work of the last years has lead to new concepts in receptor regulation with direct impact on drug design. In parallel, a new pharmacology of GPCRs emerges from the concept of allostery and biased signalling applied to these receptors.
GPCRs have also been recognized as promising tools for the engineering of cellular regulatory pathways. This involves novel techniques to control GPCR activity by redesigning ligands and/or receptor molecules, including new possibilities to control their activity with light. These approaches may eventually be applied to the field of synthetic biology and to the development of new diagnostic, preventive or therapeutic strategies.
Finally, various emerging areas in which novel GPCR functions have been discovered and will be exploited for drug development including the metabolic system will be covered by various speakers and new aspects of the research in these fields will be discussed.