Exposure to Non-Steroidal Anti-Inflammatory Drugs during Pregnancy and the Risk of Selected Birth Defects: A Prospective Cohort Study
Monday, July 18, 2011
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Proteomic Biomarkers for Acute Interstitial Lung Disease in Gefitinib-Treated Japanese Lung Cancer Patients
Wednesday, July 20, 2011
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A New Method to Address Unmet Needs for Extracting Individual Cell Migration Features from a Large Number of Cells Embedded in 3D Volumes
Friday, July 15, 2011
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Network Neighbors of Drug Targets Contribute to Drug Side-Effect Similarity
Wednesday, July 13, 2011
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Anatomical Differences Determine Distribution of Adenovirus after Convection-Enhanced Delivery to the Rat Brain
Thursday, October 13, 2011
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A Human TREK-1/HEK Cell Line: A Highly Efficient Screening Tool for Drug Development in Neurological Diseases
Friday, October 14, 2011
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Hydrogen Sulfide Attenuates Carbon Tetrachloride-Induced Hepatotoxicity, Liver Cirrhosis and Portal Hypertension in Rats
Friday, October 14, 2011
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Chronic Morphine Alters the Presynaptic Protein Profile: Identification of Novel Molecular Targets Using Proteomics and Network Analysis
Monday, October 17, 2011
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Yeast Based Small Molecule Screen for Inhibitors of SARS-CoV
Friday, December 02, 2011
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The Tyrosine Kinase Inhibitor Dasatinib Induces a Marked Adipogenic Differentiation of Human Multipotent Mesenchymal Stromal Cells
Friday, December 02, 2011
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Chinese Herbal Medicines for the Treatment of Type A H1N1 Influenza: A Systematic Review of Randomized Controlled Trials
Friday, December 02, 2011
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Publication Delay of Randomized Trials on 2009 Influenza A (H1N1) Vaccination
Friday, December 02, 2011
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The Redistribution of Power: Neurocardiac Signaling, Alcohol and Gender
Friday, December 02, 2011
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Inhibition of G Protein-Activated Inwardly Rectifying K+ Channels by Different Classes of Antidepressants
Friday, December 02, 2011
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Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis
Tuesday, December 06, 2011
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Oseltamivir Prescription and Regulatory Actions Vis-à-Vis Abnormal Behavior Risk in Japan: Drug Utilization Study Using a Nationwide Pharmacy Database
Tuesday, December 06, 2011
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Pharmacogenetic & Pharmacokinetic Biomarker for Efavirenz Based ARV and Rifampicin Based Anti-TB Drug Induced Liver Injury in TB-HIV Infected Patients
Tuesday, December 06, 2011
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Incidence of Epileptiform EEG Activity in Children during Mask Induction of Anaesthesia with Brief Administration of 8% Sevoflurane
Thursday, July 19, 2012
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Transferrin Coated Nanoparticles: Study of the Bionano Interface in Human Plasma
Thursday, July 19, 2012
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Physalin F Induces Cell Apoptosis in Human Renal Carcinoma Cells by Targeting NF-kappaB and Generating Reactive Oxygen Species
Monday, July 16, 2012
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Insertion of Short Amino-Functionalized Single-Walled Carbon Nanotubes into Phospholipid Bilayer Occurs by Passive Diffusion
Monday, July 16, 2012
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Exploration of the Association Rules Mining Technique for the Signal Detection of Adverse Drug Events in Spontaneous Reporting Systems
Monday, July 16, 2012
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N-Acetylcysteine Protects Rats with Chronic Renal Failure from Gadolinium-Chelate Nephrotoxicity
Monday, July 16, 2012
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Alleviation of Gut Inflammation by Cdx2/Pxr Pathway in a Mouse Model of Chemical Colitis
Monday, July 16, 2012
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Intracellular Retention of ABL Kinase Inhibitors Determines Commitment to Apoptosis in CML Cells
Monday, July 16, 2012
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Roflumilast-N-oxide Induces Surfactant Protein Expression in Human Alveolar Epithelial Cells Type II
Monday, July 16, 2012
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The Aryl Hydrocarbon Receptor Mediates Leflunomide-Induced Growth Inhibition of Melanoma Cells
Tuesday, July 17, 2012
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Transfer of Neuroplasticity from Nucleus Accumbens Core to Shell Is Required for Cocaine Reward
Tuesday, January 17, 2012
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Modelling of Mouse Experimental Colitis by Global Property Screens: A Holistic Approach to Assess Drug Effects in Inflammatory Bowel Disease
Wednesday, January 18, 2012
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Rapid Evaluation in Whole Blood Culture of Regimens for XDR-TB Containing PNU-100480 (Sutezolid), TMC207, PA-824, SQ109, and Pyrazinamide
Wednesday, January 18, 2012
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Synthesis, Biological Evaluation and Mechanism Studies of Deoxytylophorinine and Its Derivatives as Potential Anticancer Agents
Thursday, January 19, 2012
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Withdrawal from Cocaine Self-Administration Alters NMDA Receptor-Mediated Ca2+ Entry in Nucleus Accumbens Dendritic Spines
Friday, August 03, 2012
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A Safety Review and Meta-Analyses of Bevacizumab and Ranibizumab: Off-Label versus Goldstandard
Friday, August 03, 2012
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Markov Models of Use-Dependence and Reverse Use-Dependence during the Mouse Cardiac Action Potential
Monday, August 06, 2012
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Understanding the Basis of Drug Resistance of the Mutants of aß-Tubulin Dimer via Molecular Dynamics Simulations
Tuesday, August 07, 2012
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A VLP Vaccine Induces Broad-Spectrum Cross-Protective Antibody Immunity against H5N1 and H1N1 Subtypes of Influenza A Virus
Tuesday, August 07, 2012
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Osteopontin Reduces Biofilm Formation in a Multi-Species Model of Dental Biofilm
Tuesday, August 07, 2012
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Presynaptic Selectivity of a Ligand for Serotonin 1A Receptors Revealed by In Vivo PET Assays of Rat Brain
Tuesday, August 07, 2012
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Mephedrone in Adolescent Rats: Residual Memory Impairment and Acute but Not Lasting 5-HT Depletion
Tuesday, September 18, 2012
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Adverse Drug Reactions in Hospitalised Children in Germany Are Decreasing: Results of a Nine Year Cohort-Based Comparison
Tuesday, September 18, 2012
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Metabolomic Profiling to Identify Predictors of Response to Vitamin E for Non-Alcoholic Steatohepatitis (NASH)
Wednesday, September 19, 2012
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Valproic Acid Downregulates RBP4 and Elicits Hypervitaminosis A-Teratogenesis—A Kinetic Analysis on Retinol/Retinoic Acid Homeostatic System
Wednesday, September 19, 2012
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Local Delivery of Nimodipine by Prolonged-Release Microparticles—Feasibility, Effectiveness and Dose-Finding in Experimental Subarachnoid Hemorrhage
Tuesday, September 25, 2012
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Unexpected Neuronal Protection of SU5416 against 1-Methyl-4-Phenylpyridinium Ion-Induced Toxicity via Inhibiting Neuronal Nitric Oxide Synthase
Tuesday, September 25, 2012
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Individual and County-Level Factors Associated with Use of Multiple Prescribers and Multiple Pharmacies to Obtain Opioid Prescriptions in California
Tuesday, September 25, 2012
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A Synthetic Chloride Channel Relaxes Airway Smooth Muscle of the Rat
Wednesday, September 26, 2012
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Synergism and Rules from Combination of Baicalin, Jasminoidin and Desoxycholic acid in Refined Qing Kai Ling for Treat Ischemic Stroke Mice Model
Wednesday, September 26, 2012
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Evaluation of Environmental Contamination and Estimated Radiation Doses for the Return to Residents’ Homes in Kawauchi Village, Fukushima Prefecture
Wednesday, September 26, 2012
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Medical Care and Payment for Diabetes in China: Enormous Threat and Great Opportunity
Wednesday, September 26, 2012
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Antimalarial Activity of Potential Inhibitors of Plasmodium falciparum Lactate Dehydrogenase Enzyme Selected by Docking Studies
Thursday, July 14, 2011
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Galiellalactone Inhibits Stem Cell-Like ALDH-Positive Prostate Cancer Cells
Monday, July 11, 2011
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Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma
Wednesday, July 06, 2011
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Rescue of Photoreceptor Degeneration by Curcumin in Transgenic Rats with P23H Rhodopsin Mutation
Wednesday, June 29, 2011
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Histological Observation of Islet Hemorrhage Induced by Diagnostic Ultrasound with Contrast Agent in Rat Pancreas
Tuesday, June 28, 2011
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Escitalopram and Neuroendocrine Response in Healthy First-Degree Relatives to Depressed Patients – A Randomized Placebo-Controlled Trial
Monday, June 27, 2011
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Fisetin Lowers Methylglyoxal Dependent Protein Glycation and Limits the Complications of Diabetes
Monday, June 27, 2011
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Environmental Enrichment Preceding Early Adulthood Methylphenidate Treatment Leads to Long Term Increase of Corticosterone and Testosterone in the Rat
Friday, July 15, 2011
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Chlorpromazine Protects Against Apoptosis Induced by Exogenous Stimuli in the Developing Rat Brain
Thursday, July 14, 2011
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Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity
Wednesday, July 06, 2011
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Triple Combination Antiviral Drug (TCAD) Composed of Amantadine, Oseltamivir, and Ribavirin Impedes the Selection of Drug-Resistant Influenza A Virus
Thursday, December 29, 2011
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Inhibition of Reactive Gliosis Prevents Neovascular Growth in the Mouse Model of Oxygen-Induced Retinopathy
Thursday, July 14, 2011
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Orally Active Multi-Functional Antioxidants Are Neuroprotective in a Rat Model of Light-Induced Retinal Damage
Thursday, July 14, 2011
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Epidemiological Surveillance of Birth Defects Compatible with Thalidomide Embryopathy in Brazil
Wednesday, July 06, 2011
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AST1306, A Novel Irreversible Inhibitor of the Epidermal Growth Factor Receptor 1 and 2, Exhibits Antitumor Activity Both In Vitro and In Vivo
Monday, July 18, 2011
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Soluble Guanylate Cyclase Stimulation Prevents Fibrotic Tissue Remodeling and Improves Survival in Salt-Sensitive Dahl Rats
Monday, July 18, 2011
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Proton Pump Inhibitors Inhibit Metformin Uptake by Organic Cation Transporters (OCTs)
Thursday, July 14, 2011
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Intra-Accumbens Injection of a Dopamine Aptamer Abates MK-801-Induced Cognitive Dysfunction in a Model of Schizophrenia
Wednesday, July 13, 2011
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Reappearance of Minority K103N HIV-1 Variants after Interruption of ART Initiated during Primary HIV-1 Infection
Wednesday, July 06, 2011
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Genome-Wide Local Ancestry Approach Identifies Genes and Variants Associated with Chemotherapeutic Susceptibility in African Americans
Wednesday, July 06, 2011
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Donepezil, Anti-Alzheimer's Disease Drug, Prevents Cardiac Rupture during Acute Phase of Myocardial Infarction in Mice
Tuesday, July 05, 2011
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2-Deoxy-D-Glucose Treatment Induces Ketogenesis, Sustains Mitochondrial Function, and Reduces Pathology in Female Mouse Model of Alzheimer's Disease
Friday, July 01, 2011
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Iminosugar-Based Inhibitors of Glucosylceramide Synthase Increase Brain Glycosphingolipids and Survival in a Mouse Model of Sandhoff Disease
Wednesday, June 29, 2011
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Specific ß-Tubulin Isotypes Can Functionally Enhance or Diminish Epothilone B Sensitivity in Non-Small Cell Lung Cancer Cells
Wednesday, June 29, 2011
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Randomized Trial of Time-Limited Interruptions of Protease Inhibitor-Based Antiretroviral Therapy (ART) vs. Continuous Therapy for HIV-1 Infection
Tuesday, June 28, 2011
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Inhibitory Role of Inducible cAMP Early Repressor (ICER) in Methamphetamine-Induced Locomotor Sensitization
Tuesday, June 28, 2011
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H2S Donor, S-Propargyl-Cysteine, Increases CSE in SGC-7901 and Cancer-Induced Mice: Evidence for a Novel Anti-Cancer Effect of Endogenous H2S?
Monday, June 27, 2011
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High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria
Monday, July 25, 2011
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Frequent Use of Paracetamol and Risk of Allergic Disease Among Women in an Ethiopian Population
Thursday, July 21, 2011
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An Integrative View of Mechanisms Underlying Generalized Spike-and-Wave Epileptic Seizures and Its Implication on Optimal Therapeutic Treatments
Thursday, July 21, 2011
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A Prokaryotic S1P Lyase Degrades Extracellular S1P In Vitro and In Vivo: Implication for Treating Hyperproliferative Disorders
Monday, August 01, 2011
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Sensitive and Specific Fluorescent Probes for Functional Analysis of the Three Major Types of Mammalian ABC Transporters
Friday, July 22, 2011
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Losartan Slows Pancreatic Tumor Progression and Extends Survival of SPARC-Null Mice by Abrogating Aberrant TGFß Activation
Tuesday, February 14, 2012
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The Transcriptional Response of Caenorhabditis elegans to Ivermectin Exposure Identifies Novel Genes Involved in the Response to Reduced Food Intake
Tuesday, February 14, 2012
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Extra-Renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG2
Friday, February 10, 2012
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Activation of PKCzeta and PKMzeta in the Nucleus Accumbens Core Is Necessary for the Retrieval, Consolidation and Reconsolidation of Drug Memory
Friday, February 10, 2012
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Efficacy of Different Nitric Oxide-Based Strategies in Preventing Experimental Cerebral Malaria by Plasmodium berghei ANKA
Monday, February 13, 2012
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Quercetin-4'-O-ß-D-glucopyranoside (QODG) Inhibits Angiogenesis by Suppressing VEGFR2-Mediated Signaling in Zebrafish and Endothelial Cells
Monday, February 13, 2012
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Short- and Long-Term Cognitive Effects of Chronic Cannabinoids Administration in Late-Adolescence Rats
Monday, February 13, 2012
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Virtual Screening, Identification and In Vitro Testing of Novel Inhibitors of O-Acetyl-L-Serine Sulfhydrylase of Entamoeba histolytica
Wednesday, February 15, 2012
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Involvement of Noradrenergic Transmission in the PVN on CREB Activation, TORC1 Levels, and Pituitary-Adrenal Axis Activity during Morphine Withdrawal
Wednesday, February 15, 2012
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Necdin, a p53-Target Gene, Is an Inhibitor of p53-Mediated Growth Arrest
Wednesday, February 15, 2012
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Multi-Level Targeting of the Phosphatidylinositol-3-Kinase Pathway in Non-Small Cell Lung Cancer Cells
Wednesday, February 15, 2012
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Plasma Proteomic Profiling in HIV-1 Infected Methamphetamine Abusers
Thursday, February 16, 2012
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Targeting Lysophosphatidic Acid Signaling Retards Culture-Associated Senescence of Human Marrow Stromal Cells
Thursday, February 16, 2012
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A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity
Thursday, February 16, 2012
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Antifibrinolytic Role of a Bee Venom Serine Protease Inhibitor That Acts as a Plasmin Inhibitor
Thursday, February 16, 2012
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Metformin Reduces Hepatic Expression of SIRT3, the Mitochondrial Deacetylase Controlling Energy Metabolism
Friday, November 16, 2012
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Case-Only Designs in Pharmacoepidemiology: A Systematic Review
Friday, November 16, 2012
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A Metal-Based Inhibitor of NEDD8-Activating Enzyme
Monday, November 19, 2012
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A Novel Bioassay for the Activity Determination of Therapeutic Human Brain Natriuretic Peptide (BNP)
Monday, November 19, 2012
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Intravenous Amantadine for Freezing of Gait Resistant to Dopaminergic Therapy: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Clinical Trial
Monday, November 19, 2012
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DNA Abasic Site-Selective Enhancement of Sanguinarine Fluorescence with a Large Emission Shift
Tuesday, November 20, 2012
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Antifibrotic Effects of Roscovitine in Normal and Scleroderma Fibroblasts
Tuesday, November 20, 2012
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Levodopa Effects on Hand and Speech Movements in Patients with Parkinson’s Disease: A fMRI Study
Tuesday, October 09, 2012
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ABCB1 C3435T Polymorphism and Response to Clopidogrel Treatment in Coronary Artery Disease (CAD) Patients: A Meta-Analysis
Tuesday, October 09, 2012
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Adverse Events of Pirfenidone for the Treatment of Pulmonary Fibrosis: A Meta-Analysis of Randomized Controlled Trials
Tuesday, October 09, 2012
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Role of Corticotropin-Releasing Factor (CRF) Receptor-1 on the Catecholaminergic Response to Morphine Withdrawal in the Nucleus Accumbens (NAc)
Wednesday, October 10, 2012
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A Purpose-Synthesised Anti-Fibrotic Agent Attenuates Experimental Kidney Diseases in the Rat
Wednesday, October 10, 2012
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Attenuation of Renovascular Damage in Zucker Diabetic Fatty Rat by NWT-03, an Egg Protein Hydrolysate with ACE- and DPP4-Inhibitory Activity
Wednesday, October 10, 2012
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Low-Dose Oral Sirolimus and the Risk of Menstrual-Cycle Disturbances and Ovarian Cysts: Analysis of the Randomized Controlled SUISSE ADPKD Trial
Wednesday, October 10, 2012
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Improved Inhibitor Screening Experiments by Comparative Analysis of Simulated Enzyme Progress Curves
Wednesday, October 10, 2012
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Oroxylin-A Rescues LPS-Induced Acute Lung Injury via Regulation of NF-?B Signaling Pathway in Rodents
Wednesday, October 10, 2012
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Synergistic Antitumor Effects of Endostar in Combination with Oxaliplatin via Inhibition of HIF and CXCR4 in the Colorectal Cell Line SW1116
Wednesday, October 10, 2012
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Potential Drug-Drug Interactions in Prescriptions to Patients over 45 Years of Age in Primary Care, Southern Brazil
Wednesday, October 10, 2012
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Enhancing Communication about Paediatric Medicines: Lessons from a Qualitative Study of Parents' Experiences of Their Child's Suspected Adverse Drug Reaction
Wednesday, October 10, 2012
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Combinatorial Pharmacogenetic Interactions of Bucindolol and ß1, a2C Adrenergic Receptor Polymorphisms
Wednesday, October 10, 2012
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Violacein Induces Death of Resistant Leukaemia Cells via Kinome Reprogramming, Endoplasmic Reticulum Stress and Golgi Apparatus Collapse
Thursday, October 11, 2012
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Small-Molecule Quinolinol Inhibitor Identified Provides Protection against BoNT/A in Mice
Thursday, October 11, 2012
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Macrophages Sequester Clofazimine in an Intracellular Liquid Crystal-Like Supramolecular Organization
Thursday, October 11, 2012
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Puerarin Suppresses Proliferation of Endometriotic Stromal Cells Partly via the MAPK Signaling Pathway Induced by 17ß-estradiol-BSA
Wednesday, September 19, 2012
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Salinomycin Induces Autophagy in Colon and Breast Cancer Cells with Concomitant Generation of Reactive Oxygen Species
Wednesday, September 19, 2012
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Prevention of Disuse Muscle Atrophy by Dietary Ingestion of 8-Prenylnaringenin in Denervated Mice
Wednesday, September 19, 2012
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Identification of Early Biomarkers during Acetaminophen-Induced Hepatotoxicity by Fourier Transform Infrared Microspectroscopy
Wednesday, September 19, 2012
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Use of Fibrates and Cancer Risk: A Systematic Review and Meta-Analysis of 17 Long-Term Randomized Placebo-Controlled Trials
Wednesday, September 19, 2012
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A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity
Wednesday, September 19, 2012
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Effects of Paclitaxel on EGFR Endocytic Trafficking Revealed Using Quantum Dot Tracking in Single Cells
Thursday, September 20, 2012
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High-Throughput 1,536-Well Fluorescence Polarization Assays for a1-Acid Glycoprotein and Human Serum Albumin Binding
Thursday, September 20, 2012
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Activation Biosensor for G Protein-Coupled Receptors: A FRET-Based m1 Muscarinic Activation Sensor That Regulates Gq
Thursday, September 20, 2012
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Reverting Antibiotic Tolerance of Pseudomonas aeruginosa PAO1 Persister Cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one
Thursday, September 20, 2012
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Eicosapentaenoic Acid and Oxypurinol in the Treatment of Muscle Wasting in a Mouse Model of Cancer Cachexia
Thursday, September 20, 2012
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Worsening Endothelial Function with Efavirenz Compared to Protease Inhibitors: A 12-Month Prospective Study
Thursday, September 20, 2012
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A Pilot Study to Examine the Effect of Chronic Treatment with Immunosuppressive Drugs on Mucociliary Clearance in a Vagotomized Murine Model
Thursday, September 20, 2012
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A 10-Year Analysis of the Effects of Media Coverage of Regulatory Warnings on Antidepressant Use in The Netherlands and UK
Thursday, September 20, 2012
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Impairment of Retrograde Neuronal Transport in Oxaliplatin-Induced Neuropathy Demonstrated by Molecular Imaging
Thursday, September 20, 2012
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The Monoamine Re-Uptake Inhibitor UWA-101 Improves Motor Fluctuations in the MPTP-Lesioned Common Marmoset
Thursday, September 20, 2012
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The Cardiac Ventricular 5-HT4 Receptor Is Functional in Late Foetal Development and Is Reactivated in Heart Failure
Thursday, September 20, 2012
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A Nested Case-Control Study of Intrauterine Exposure to Persistent Organochlorine Pollutants and the Risk of Hypospadias
Thursday, September 27, 2012
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Functional Characterisation of the WW Minimal Domain for Delivering Therapeutic Proteins by Adenovirus Dodecahedron
Thursday, September 27, 2012
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Anti-Inflammatory and Cardioprotective Effects of Tadalafil in Diabetic Mice
Friday, September 21, 2012
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Muscarinic Receptors in Amygdala Control Trace Fear Conditioning
Friday, September 21, 2012
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Identification of Novel Human Dipeptidyl Peptidase-IV Inhibitors of Natural Origin (Part II): In Silico Prediction in Antidiabetic Extracts
Friday, September 21, 2012
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Respiratory Paradoxical Adverse Drug Reactions Associated with Acetylcysteine and Carbocysteine Systemic Use in Paediatric Patients: A National Survey
Wednesday, July 27, 2011
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Genomic Regions Identified by Overlapping Clusters of Nominally-Positive SNPs from Genome-Wide Studies of Alcohol and Illegal Substance Dependence
Wednesday, July 27, 2011
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Metabolic Effects of Fluoxetine in Adults with Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Placebo-Controlled Trials
Thursday, July 28, 2011
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Evaluation of Un-Medicated, Self-Paced Alcohol Withdrawal
Thursday, July 28, 2011
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Inflammation and In-Stent Restenosis: The Role of Serum Markers and Stent Characteristics in Carotid Artery Stenting
Thursday, July 28, 2011
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Predicting P-Glycoprotein-Mediated Drug Transport Based On Support Vector Machine and Three-Dimensional Crystal Structure of P-glycoprotein
Tuesday, October 04, 2011
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Long-Stay Psychiatric Patients: A Prospective Study Revealing Persistent Antipsychotic-Induced Movement Disorder
Monday, October 03, 2011
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Effect of Sulindac Sulfide on Metallohydrolases in the Human Colon Cancer Cell Line HT-29
Monday, October 03, 2011
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Increased Risk for Invasive Breast Cancer Associated with Hormonal Therapy: A Nation-Wide Random Sample of 65,723 Women Followed from 1997 to 2008
Thursday, October 06, 2011
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Hyperforin Inhibits Akt1 Kinase Activity and Promotes Caspase-Mediated Apoptosis Involving Bad and Noxa Activation in Human Myeloid Tumor Cells
Thursday, October 06, 2011
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Identification of New Genes Involved in Human Adipogenesis and Fat Storage
Monday, February 27, 2012
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Comparative Gene Expression Profiling of P. falciparum Malaria Parasites Exposed to Three Different Histone Deacetylase Inhibitors
Monday, February 27, 2012
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(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice
Monday, February 27, 2012
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Core Site-Moiety Maps Reveal Inhibitors and Binding Mechanisms of Orthologous Proteins by Screening Compound Libraries
Wednesday, February 29, 2012
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Capacity for Absorption of Water-Soluble Secondary Metabolites Greater in Birds than in Rodents
Tuesday, February 28, 2012
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Suppression of FOXM1 Sensitizes Human Cancer Cells to Cell Death Induced by DNA-Damage
Wednesday, February 29, 2012
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Influence of IL28B Polymorphisms on Response to a Lower-Than-Standard Dose peg-IFN-a 2a for Genotype 3 Chronic Hepatitis C in HIV-Coinfected Patients
Tuesday, January 03, 2012
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Protective Effects of a Rhodiola Crenulata Extract and Salidroside on Hippocampal Neurogenesis against Streptozotocin-Induced Neural Injury in the Rat
Tuesday, January 03, 2012
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The Dopamine Augmenter L-DOPA Does Not Affect Positive Mood in Healthy Human Volunteers
Wednesday, January 04, 2012
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GW8510 Increases Insulin Expression in Pancreatic Alpha Cells through Activation of p53 Transcriptional Activity
Thursday, January 05, 2012
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Impedance Responses Reveal ß2-Adrenergic Receptor Signaling Pluridimensionality and Allow Classification of Ligands with Distinct Signaling Profiles
Thursday, January 05, 2012
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A Novel Strategy for Development of Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model
Friday, January 06, 2012
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Inhibition of Both Protease and Helicase Activities of Hepatitis C Virus NS3 by an Ethyl Acetate Extract of Marine Sponge Amphimedon sp
Wednesday, November 07, 2012
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Molecular Epidemiology of Human Immunodeficiency Virus Type 1 in Guangdong Province of Southern China
Wednesday, November 07, 2012
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Long-Term Survival in HIV Positive Patients with up to 15 Years of Antiretroviral Therapy
Wednesday, November 07, 2012
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Urine from Treated Cattle Drives Selection for Cephalosporin Resistant Escherichia coli in Soil
Wednesday, November 07, 2012
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Indocyanine Green-Assisted Internal Limiting Membrane Peeling in Macular Hole Surgery: A Meta-Analysis
Wednesday, November 07, 2012
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Low Dose Nicotine and Antagonism of ß2 Subunit Containing Nicotinic Acetylcholine Receptors Have Similar Effects on Affective Behavior in Mice
Wednesday, November 07, 2012
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Risk of Dementia in Patients with Insomnia and Long-term Use of Hypnotics: A Population-based Retrospective Cohort Study
Wednesday, November 07, 2012
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A Non-Synonymous Single Nucleotide Polymorphism in an OPRM1 Splice Variant Is Associated with Fentanyl-Induced Emesis in Women Undergoing Minor Gynaecological Surgery
Wednesday, November 07, 2012
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A Personalized BEST: Characterization of Latent Clinical Classes of Nonischemic Heart Failure That Predict Outcomes and Response to Bucindolol
Wednesday, November 07, 2012
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The Soluble Guanylyl Cyclase Activator Bay 58-2667 Selectively Limits Cardiomyocyte Hypertrophy
Wednesday, November 07, 2012
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Hypoxia-Inducible Factor Activation Protects the Kidney from Gentamicin-Induced Acute Injury
Thursday, November 08, 2012
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Effects of the CK2 Inhibitors CX-4945 and CX-5011 on Drug-Resistant Cells
Thursday, November 08, 2012
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Supplementation of Persimmon Leaf Ameliorates Hyperglycemia, Dyslipidemia and Hepatic Fat Accumulation in Type 2 Diabetic Mice
Thursday, November 08, 2012
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Differences in HCV Viral Decline between Low and Standard-Dose Pegylated-Interferon-Alpha-2a with Ribavirin in HIV/HCV Genotype 3 Patients
Thursday, November 08, 2012
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Activation of Haem-Oxidized Soluble Guanylyl Cyclase with BAY 60-2770 in Human Platelets Lead to Overstimulation of the Cyclic GMP Signaling Pathway
Thursday, November 08, 2012
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Identification of Anti-Malarial Compounds as Novel Antagonists to Chemokine Receptor CXCR4 in Pancreatic Cancer Cells
Friday, February 03, 2012
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Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination
Wednesday, February 08, 2012
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Cellular Growth Kinetics Distinguish a Cyclophilin Inhibitor from an HSP90 Inhibitor as a Selective Inhibitor of Hepatitis C Virus
Wednesday, February 08, 2012
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Over-Expression of a Cytochrome P450 Is Associated with Resistance to Pyriproxyfen in the Greenhouse Whitefly Trialeurodes vaporariorum
Wednesday, February 08, 2012
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Gene Expression Profiling of Dendritic Cells in Different Physiological Stages under Cordyceps sinensis Treatment
Thursday, July 19, 2012
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Immunotherapeutic Targeting of Membrane Hsp70-Expressing Tumors Using Recombinant Human Granzyme B
Thursday, July 19, 2012
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Effect of Intravitreal Anti-Vascular Endothelial Growth Factor Therapy on the Risk of Arterial Thromboembolic Events: A Meta-Analysis
Thursday, July 19, 2012
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Using Poison Center Exposure Calls to Predict Methadone Poisoning Deaths
Thursday, July 19, 2012
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Temporal Patterns of Medications Dispensed to Children and Adolescents in a National Insured Population
Thursday, July 19, 2012
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Bezafibrate for X-Linked Adrenoleukodystrophy
Friday, July 20, 2012
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An Acenocoumarol Dosing Algorithm Using Clinical and Pharmacogenetic Data in Spanish Patients with Thromboembolic Disease
Friday, July 20, 2012
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Staphylococcus aureus in Continuous Culture: A Tool for the Rational Design of Antibiotic Treatment Protocols
Friday, July 20, 2012
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Challenges in Coding Adverse Events in Clinical Trials: A Systematic Review
Friday, July 20, 2012
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Plant Extract Synthesized PLA Nanoparticles for Controlled and Sustained Release of Quercetin: A Green Approach
Monday, July 23, 2012
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A Naturally Occurring Hypoallergenic Variant of Vespid Antigen 5 from Polybia scutellaris Venom as a Candidate for Allergen-Specific Immunotherapy
Monday, July 23, 2012
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DIOL Triterpenes Block Profibrotic Effects of Angiotensin II and Protect from Cardiac Hypertrophy
Monday, July 23, 2012
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Guanidylation and Tail Effects in Cationic Antimicrobial Lipopeptoids
Monday, July 23, 2012
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Identifying Novel Drug Indications through Automated Reasoning
Monday, July 23, 2012
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Cost-Effectiveness of Peer-Delivered Interventions for Cocaine and Alcohol Abuse among Women: A Randomized Controlled Trial
Tuesday, March 20, 2012
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Folate Decorated Dual Drug Loaded Nanoparticle: Role of Curcumin in Enhancing Therapeutic Potential of Nutlin-3a by Reversing Multidrug Resistance
Wednesday, March 21, 2012
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Exploiting Adaptive Laboratory Evolution of Streptomyces clavuligerus for Antibiotic Discovery and Overproduction
Wednesday, March 21, 2012
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The p21-Dependent Radiosensitization of Human Breast Cancer Cells by MLN4924, an Investigational Inhibitor of NEDD8 Activating Enzyme
Thursday, March 22, 2012
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Maxadilan Prevents Apoptosis in iPS Cells and Shows No Effects on the Pluripotent State or Karyotype
Friday, March 23, 2012
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Computable Features Required to Evaluate the Efficacy of Drugs and a Universal Algorithm to Find Optimally Effective Drug in a Drug Complex
Friday, March 23, 2012
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Characterization of a FGF19 Variant with Altered Receptor Specificity Revealed a Central Role for FGFR1c in the Regulation of Glucose Metabolism
Friday, March 23, 2012
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Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/ß-Catenin Pathway
Friday, December 16, 2011
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The Endocrine Disruptor Mono-(2-Ethylhexyl) Phthalate Affects the Differentiation of Human Liposarcoma Cells (SW 872)
Wednesday, December 21, 2011
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Systematic Drug Repositioning Based on Clinical Side-Effects
Wednesday, December 21, 2011
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Novel Patient Cell-Based HTS Assay for Identification of Small Molecules for a Lysosomal Storage Disease
Wednesday, December 21, 2011
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Binding of Tetracycline and Chlortetracycline to the Enzyme Trypsin: Spectroscopic and Molecular Modeling Investigations
Monday, December 19, 2011
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A Fly in the Ointment: Evaluation of Traditional Use of Plants to Repel and Kill Blowfly Larvae in Fermented Fish
Monday, December 19, 2011
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Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays
Monday, December 19, 2011
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Mitragynine Attenuates Withdrawal Syndrome in Morphine-Withdrawn Zebrafish
Wednesday, December 21, 2011
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ACSL6 Is Associated with the Number of Cigarettes Smoked and Its Expression Is Altered by Chronic Nicotine Exposure
Tuesday, December 20, 2011
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Mechanisms of MEOX1 and MEOX2 Regulation of the Cyclin Dependent Kinase Inhibitors p21CIP1/WAF1 and p16INK4a in Vascular Endothelial Cells
Tuesday, December 20, 2011
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Molecular Mechanisms of Bortezomib Resistant Adenocarcinoma Cells
Thursday, December 22, 2011
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Safety and Reactogenicity of Canarypox ALVAC-HIV (vCP1521) and HIV-1 gp120 AIDSVAX B/E Vaccination in an Efficacy Trial in Thailand
Wednesday, December 21, 2011
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Chlorogenic Acid Stimulates Glucose Transport in Skeletal Muscle via AMPK Activation: A Contributor to the Beneficial Effects of Coffee on Diabetes
Wednesday, March 07, 2012
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5-Fluorouracil Induced Intestinal Mucositis via Nuclear Factor-?B Activation by Transcriptomic Analysis and In Vivo Bioluminescence Imaging
Wednesday, March 07, 2012
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Pre-Clinical Evaluation of a 213Bi-Labeled 2556 Antibody to HIV-1 gp41 Glycoprotein in HIV-1 Mouse Models as a Reagent for HIV Eradication
Friday, March 09, 2012
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Evidence for the Contribution of the Hemozoin Synthesis Pathway of the Murine Plasmodium yoelii to the Resistance to Artemisinin-Related Drugs
Monday, March 05, 2012
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Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture
Friday, January 27, 2012
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Plastic and Heritable Components of Phenotypic Variation in Nucella lapillus: An Assessment Using Reciprocal Transplant and Common Garden Experiments
Friday, January 27, 2012
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Interactive Effects of Large- and Small-Scale Sources of Feral Honey-Bees for Sunflower in the Argentine Pampas
Friday, January 27, 2012
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Consistent Pattern of Local Adaptation during an Experimental Heat Wave in a Pipefish-Trematode Host-Parasite System
Friday, January 27, 2012
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Synergistic TLR2/6 and TLR9 Activation Protects Mice against Lethal Influenza Pneumonia
Friday, January 27, 2012
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Induction of Heterosubtypic Cross-Protection against Influenza by a Whole Inactivated Virus Vaccine: The Role of Viral Membrane Fusion Activity
Friday, January 27, 2012
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Immunohistochemical Profile for Unknown Primary Adenocarcinoma
Friday, January 27, 2012
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Antibody to P. falciparum in Pregnancy Varies with Intermittent Preventive Treatment Regime and Bed Net Use
Friday, January 27, 2012
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Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models
Friday, January 27, 2012
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Interventions to Influence Consulting and Antibiotic Use for Acute Respiratory Tract Infections in Children: A Systematic Review and Meta-Analysis
Friday, January 27, 2012
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A Piezoelectric Immunosensor Using Hybrid Self-Assembled Monolayers for Detection of Schistosoma japonicum
Friday, January 27, 2012
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Patient's Origin and Lifestyle Associated with CTX-M-Producing Escherichia coli: A Case-Control-Control Study
Friday, January 27, 2012
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A Bovine Model of Respiratory Chlamydia psittaci Infection: Challenge Dose Titration
Friday, January 27, 2012
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Does a Family Meetings Intervention Prevent Depression and Anxiety in Family Caregivers of Dementia Patients? A Randomized Trial
Friday, January 27, 2012
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LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth
Friday, January 27, 2012
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MIR-99a and MIR-99b Modulate TGF-ß Induced Epithelial to Mesenchymal Plasticity in Normal Murine Mammary Gland Cells
Friday, January 27, 2012
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Reorganizing the Intrinsic Functional Architecture of the Human Primary Motor Cortex during Rest with Non-Invasive Cortical Stimulation
Friday, January 27, 2012
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The Cost of Universal Health Care in India: A Model Based Estimate
Friday, January 27, 2012
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Myocardial Alternative RNA Splicing and Gene Expression Profiling in Early Stage Hypoplastic Left Heart Syndrome
Friday, January 27, 2012
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ERK1 Regulates the Hematopoietic Stem Cell Niches
Monday, January 30, 2012
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Simulated Warming Differentially Affects the Growth and Competitive Ability of Centaurea maculosa Populations from Home and Introduced Ranges
Monday, January 30, 2012
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Seeing Emotion with Your Ears: Emotional Prosody Implicitly Guides Visual Attention to Faces
Monday, January 30, 2012
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CCL2 Is Associated with a Faster Rate of Cognitive Decline during Early Stages of Alzheimer's Disease
Monday, January 30, 2012
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Quality Control and Performance of HIV Rapid Tests in a Microbicide Clinical Trial in Rural KwaZulu-Natal
Monday, January 30, 2012
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Automated Workflow for Preparation of cDNA for Cap Analysis of Gene Expression on a Single Molecule Sequencer
Monday, January 30, 2012
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TBX21 and HLX1 Polymorphisms Influence Cytokine Secretion at Birth
Monday, January 30, 2012
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Metabolic Profiles and cDNA-AFLP Analysis of Salvia miltiorrhiza and Salvia castanea Diel f. tomentosa Stib
Monday, January 30, 2012
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An Ensemble Classifier for Eukaryotic Protein Subcellular Location Prediction Using Gene Ontology Categories and Amino Acid Hydrophobicity
Monday, January 30, 2012
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Catalog of MicroRNA Seed Polymorphisms in Vertebrates
Friday, January 27, 2012
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Access to Barrier Perches Improves Behavior Repertoire in Broilers
Friday, January 27, 2012
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Predicting Target DNA Sequences of DNA-Binding Proteins Based on Unbound Structures
Wednesday, February 01, 2012
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Environmentally Realistic Exposure to the Herbicide Atrazine Alters Some Sexually Selected Traits in Male Guppies
Wednesday, February 01, 2012
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Conditional Ablation of Ezh2 in Murine Hearts Reveals Its Essential Roles in Endocardial Cushion Formation, Cardiomyocyte Proliferation and Survival
Wednesday, February 01, 2012
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Responsiveness to 6-n-Propylthiouracil (PROP) Is Associated with Salivary Levels of Two Specific Basic Proline-Rich Proteins in Humans
Wednesday, February 01, 2012
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Viremic HIV Infected Individuals with High CD4 T Cells and Functional Envelope Proteins Show Anti-gp41 Antibodies with Unique Specificity and Function
Wednesday, February 01, 2012
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Implications of Extreme Life Span in Clonal Organisms: Millenary Clones in Meadows of the Threatened Seagrass Posidonia oceanica
Wednesday, February 01, 2012
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Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families
Wednesday, February 01, 2012
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In Silico Insights into the Symbiotic Nitrogen Fixation in Sinorhizobium meliloti via Metabolic Reconstruction
Wednesday, February 01, 2012
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Defining Plasmodium falciparum Treatment in South West Asia: A Randomized Trial Comparing Artesunate or Primaquine Combined with Chloroquine or SP
Tuesday, January 31, 2012
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Early Cell Death Detection with Digital Holographic Microscopy
Tuesday, January 31, 2012
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A Role for VEGFR2 Activation in Endothelial Responses Caused by Barrier Disruptive OxPAPC Concentrations
Tuesday, January 31, 2012
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A New Eusuchian Crocodyliform with Novel Cranial Integument and Its Significance for the Origin and Evolution of Crocodylia
Tuesday, January 31, 2012
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Increased Inter-Colony Fusion Rates Are Associated with Reduced COI Haplotype Diversity in an Invasive Colonial Ascidian Didemnum vexillum
Tuesday, January 31, 2012
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Ologs: A Categorical Framework for Knowledge Representation
Tuesday, January 31, 2012
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Primary Xenografts of Human Prostate Tissue as a Model to Study Angiogenesis Induced by Reactive Stroma
Tuesday, January 31, 2012
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Novel, Objective, Multivariate Biomarkers Composed of Plasma Amino Acid Profiles for the Diagnosis and Assessment of Inflammatory Bowel Disease
Tuesday, January 31, 2012
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Increased GABAA Receptor e-Subunit Expression on Ventral Respiratory Column Neurons Protects Breathing during Pregnancy
Tuesday, January 31, 2012
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Boolean Models of Biosurfactants Production in Pseudomonas fluorescens
Tuesday, January 31, 2012
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Homology Inference of Protein-Protein Interactions via Conserved Binding Sites
Tuesday, January 31, 2012
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The Risk of Stroke after Percutaneous Vertebroplasty for Osteoporosis: A Population-Based Cohort Study
Tuesday, January 31, 2012
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Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types
Wednesday, February 01, 2012
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Polyglutamine Repeats Are Associated to Specific Sequence Biases That Are Conserved among Eukaryotes
Wednesday, February 01, 2012
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Season of Sampling and Season of Birth Influence Serotonin Metabolite Levels in Human Cerebrospinal Fluid
Wednesday, February 01, 2012
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Eradication of Metastatic Renal Cell Carcinoma after Adenovirus-Encoded TNF-Related Apoptosis-Inducing Ligand (TRAIL)/CpG Immunotherapy
Wednesday, February 01, 2012
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Two-Item Sentence Comprehension by a Dog (Canis familiaris)
Wednesday, February 01, 2012
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Tobacco Rattle Virus Vector: A Rapid and Transient Means of Silencing Manduca sexta Genes by Plant Mediated RNA Interference
Wednesday, February 01, 2012
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Mitogen- and Stress-Activated Kinase 1 (MSK1) Regulates Cigarette Smoke-Induced Histone Modifications on NF-?B-dependent Genes
Wednesday, February 01, 2012
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Genetic Association Analysis Using Sibship Data: A Multilevel Model Approach
Wednesday, February 01, 2012
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Helicobacter pylori CagA Triggers Expression of the Bactericidal Lectin REG3? via Gastric STAT3 Activation
Wednesday, February 01, 2012
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Mimicry of Food Intake: The Dynamic Interplay between Eating Companions
Wednesday, February 01, 2012
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Innate Sex Differences in the Timing of Spring Migration in a Songbird
Wednesday, February 01, 2012
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Sleep Disorders and Demand for Medical Services: Evidence from a Population-Based Longitudinal Study
Wednesday, February 01, 2012
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Potent Phototoxicity of Marine Bunker Oil to Translucent Herring Embryos after Prolonged Weathering
Wednesday, February 01, 2012
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From Food to Offspring Down: Tissue-Specific Discrimination and Turn-Over of Stable Isotopes in Herbivorous Waterbirds and Other Avian Foraging Guilds
Wednesday, February 01, 2012
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Trans-Synaptic Spread of Tau Pathology In Vivo
Wednesday, February 01, 2012
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Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling
Wednesday, February 01, 2012
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NGS QC Toolkit: A Toolkit for Quality Control of Next Generation Sequencing Data
Wednesday, February 01, 2012
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Murine GRPR and Stathmin Control in Opposite Directions both Cued Fear Extinction and Neural Activities of the Amygdala and Prefrontal Cortex
Wednesday, February 01, 2012
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S-LOCUS EARLY FLOWERING 3 Is Exclusively Present in the Genomes of Short-Styled Buckwheat Plants that Exhibit Heteromorphic Self-Incompatibility
Wednesday, February 01, 2012
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Measuring the Impacts of Community-based Grasslands Management in Mongolia's Gobi
Wednesday, February 01, 2012
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Knowledge-Based Reconstruction of mRNA Transcripts with Short Sequencing Reads for Transcriptome Research
Wednesday, February 01, 2012
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CenSeam, an International Program on Seamounts within the Census of Marine Life: Achievements and Lessons Learned
Wednesday, February 01, 2012
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Can Phlorotannins Purified Extracts Constitute a Novel Pharmacological Alternative for Microbial Infections with Associated Inflammatory Conditions?
Thursday, February 02, 2012
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Activation and Inhibition of Transglutaminase 2 in Mice
Thursday, February 02, 2012
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Gu-4 Suppresses Affinity and Avidity Modulation of CD11b and Improves the Outcome of Mice with Endotoxemia and Sepsis
Thursday, February 02, 2012
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Lithium Treatment of APPSwDI/NOS2-/- Mice Leads to Reduced Hyperphosphorylated Tau, Increased Amyloid Deposition and Altered Inflammatory Phenotype
Thursday, February 09, 2012
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Caffeic Acid Phenethyl Ester and Its Amide Analogue Are Potent Inhibitors of Leukotriene Biosynthesis in Human Polymorphonuclear Leukocytes
Thursday, February 09, 2012
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Noradrenergic a1 Receptor Antagonist Treatment Attenuates Positive Subjective Effects of Cocaine in Humans: A Randomized Trial
Friday, February 03, 2012
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Toxicity Associated with Stavudine Dose Reduction from 40 to 30 mg in First-Line Antiretroviral Therapy
Monday, November 21, 2011
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Health Behaviors, Care Needs and Attitudes towards Self-Prescription: A Cross-Sectional Survey among Dutch Medical Students
Monday, November 21, 2011
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Prevalence of Antidepressant Prescription or Use in Patients with Acute Coronary Syndrome: A Systematic Review
Tuesday, November 22, 2011
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In Vitro Effects of Pirfenidone on Cardiac Fibroblasts: Proliferation, Myofibroblast Differentiation, Migration and Cytokine Secretion
Wednesday, November 23, 2011
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Which Compound to Select in Lead Optimization? Prospectively Validated Proteochemometric Models Guide Preclinical Development
Wednesday, November 23, 2011
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Lithium Monotherapy Increases ACTH and Cortisol Response in the Dex/CRH Test in Unipolar Depressed Subjects. A Study with 30 Treatment-Naive Patients
Wednesday, November 23, 2011
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Resistance Patterns Selected by Nevirapine vs. Efavirenz in HIV-Infected Patients Failing First-Line Antiretroviral Treatment: A Bayesian Analysis
Wednesday, November 23, 2011
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Molecular Determinants of Magnolol Targeting Both RXRa and PPAR?
Tuesday, November 29, 2011
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Peroxisome Proliferator-Activated Receptor-Gamma Agonists Suppress Tissue Factor Overexpression in Rat Balloon Injury Model with Paclitaxel Infusion
Tuesday, November 29, 2011
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Mangafodipir Protects against Hepatic Ischemia-Reperfusion Injury in Mice
Wednesday, November 02, 2011
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PLGA, PLGA-TMC and TMC-TPP Nanoparticles Differentially Modulate the Outcome of Nasal Vaccination by Inducing Tolerance or Enhancing Humoral Immunity
Wednesday, November 02, 2011
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Suicidal Behavior and Depression in Smoking Cessation Treatments
Wednesday, November 02, 2011
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Typologies of Prescription Opioid Use in a Large Sample of Adults Assessed for Substance Abuse Treatment
Wednesday, November 02, 2011
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ß-AR Blockers Suppresses ER Stress in Cardiac Hypertrophy and Heart Failure
Wednesday, November 02, 2011
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EGFR-Targeted Hybrid Plasmonic Magnetic Nanoparticles Synergistically Induce Autophagy and Apoptosis in Non-Small Cell Lung Cancer Cells
Monday, November 07, 2011
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Gene Expression-Based Chemical Genomics Identifies Potential Therapeutic Drugs in Hepatocellular Carcinoma
Monday, November 07, 2011
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Camphene, a Plant-Derived Monoterpene, Reduces Plasma Cholesterol and Triglycerides in Hyperlipidemic Rats Independently of HMG-CoA Reductase Activity
Thursday, November 03, 2011
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Unmasking Differential Effects of Rosiglitazone and Pioglitazone in the Combination Treatment with n-3 Fatty Acids in Mice Fed a High-Fat Diet
Thursday, November 03, 2011
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Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular Mechanisms
Tuesday, November 08, 2011
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A Two-Compartment Model of VEGF Distribution in the Mouse
Tuesday, November 08, 2011
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Context Mediates Antimicrobial Efficacy of Kinocidin Congener Peptide RP-1
Friday, November 04, 2011
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Perturbation of Host Cell Cytoskeleton by Cranberry Proanthocyanidins and Their Effect on Enteric Infections
Friday, November 04, 2011
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Urocortin-1 within the Centrally-Projecting Edinger-Westphal Nucleus Is Critical for Ethanol Preference
Friday, October 28, 2011
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Halofuginone Has Anti-Proliferative Effects in Acute Promyelocytic Leukemia by Modulating the Transforming Growth Factor Beta Signaling Pathway
Friday, October 28, 2011
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Expression of p53 in the Effects of Artesunate on Induction of Apoptosis and Inhibition of Proliferation in Rat Primary Hepatic Stellate Cells
Friday, October 28, 2011
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Transcriptional and Functional Analysis of the Effects of Magnolol: Inhibition of Autolysis and Biofilms in Staphylococcus aureus
Friday, October 28, 2011
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Association between Multi-Dose Drug Dispensing and Quality of Drug Treatment – A Register-Based Study
Monday, October 31, 2011
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Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis
Tuesday, November 01, 2011
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Activation of Sirt1 by Resveratrol Inhibits TNF-a Induced Inflammation in Fibroblasts
Tuesday, November 01, 2011
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An Inducible Cell-Cell Fusion System with Integrated Ability to Measure the Efficiency and Specificity of HIV-1 Entry Inhibitors
Tuesday, November 01, 2011
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Adjuvant Chemotherapy, with or without Taxanes, in Early or Operable Breast Cancer: A Meta-Analysis of 19 Randomized Trials with 30698 Patients
Tuesday, November 01, 2011
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Bilateral Fronto-Parietal Integrity in Young Chronic Cigarette Smokers: A Diffusion Tensor Imaging Study
Tuesday, November 01, 2011
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Calcium-Based Nanoparticles Accelerate Skin Wound Healing
Wednesday, November 02, 2011
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Rad51 and BRCA2 - New Molecular Targets for Sensitizing Glioma Cells to Alkylating Anticancer Drugs
Wednesday, November 02, 2011
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Predicting In Vivo Anti-Hepatofibrotic Drug Efficacy Based on In Vitro High-Content Analysis
Wednesday, November 02, 2011
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Rivastigmine Lowers Aß and Increases sAPPa Levels, Which Parallel Elevated Synaptic Markers and Metabolic Activity in Degenerating Primary Rat Neurons
Friday, July 22, 2011
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Levothyroxine Monotherapy Cannot Guarantee Euthyroidism in All Athyreotic Patients
Monday, August 01, 2011
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Impact of Small Body Weight on Tenofovir-Associated Renal Dysfunction in HIV-Infected Patients: A Retrospective Cohort Study of Japanese Patients
Monday, July 25, 2011
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Spherical Harmonics Coefficients for Ligand-Based Virtual Screening of Cyclooxygenase Inhibitors
Wednesday, July 27, 2011
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Proteomic Analysis Shows Synthetic Oleanane Triterpenoid Binds to mTOR
Wednesday, July 27, 2011
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Duloxetine Inhibits Effects of MDMA (“Ecstasy") In Vitro and in Humans in a Randomized Placebo-Controlled Laboratory Study
Friday, May 04, 2012
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Hypothalamic Orexin-A Neurons Are Involved in the Response of the Brain Stress System to Morphine Withdrawal
Wednesday, May 09, 2012
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Anti-Inflammatory Activities of Inotilone from Phellinus linteus through the Inhibition of MMP-9, NF-?B, and MAPK Activation In Vitro and In Vivo
Tuesday, May 08, 2012
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In Silico Assessment of Potential Druggable Pockets on the Surface of a1-Antitrypsin Conformers
Tuesday, May 08, 2012
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Pharmacogenetics Meets Metabolomics: Discovery of Tryptophan as a New Endogenous OCT2 Substrate Related to Metformin Disposition
Tuesday, May 08, 2012
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Gastrointestinal-Sparing Effects of Novel NSAIDs in Rats with Compromised Mucosal Defence
Monday, April 09, 2012
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White Matter Abnormalities Correlating with Memory and Depression in Heroin Users under Methadone Maintenance Treatment
Monday, April 09, 2012
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Effects of Smoking and Cessation on Subclinical Arterial Disease: A Substudy of a Randomized Controlled Trial
Monday, April 09, 2012
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Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells
Tuesday, April 10, 2012
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Identification of Critical Amino Acids in an Immunodominant IgE Epitope of Pen c 13, a Major Allergen from Penicillium citrinum
Tuesday, April 10, 2012
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Structural and Functional Diversity of Acidic Scorpion Potassium Channel Toxins
Thursday, April 12, 2012
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Proteomic Candidate Biomarkers of Drug-Induced Nephrotoxicity in the Rat
Wednesday, April 11, 2012
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Computational Modeling-Based Discovery of Novel Classes of Anti-Inflammatory Drugs That Target Lanthionine Synthetase C-Like Protein 2
Wednesday, April 11, 2012
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Beneficial Metabolic Effects of 2',3',5'-tri-acetyl-N6- (3-Hydroxylaniline) Adenosine in the Liver and Plasma of Hyperlipidemic Hamsters
Wednesday, March 28, 2012
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Characterization of Rhodamine-123 as a Tracer Dye for Use In In vitro Drug Transport Assays
Wednesday, March 28, 2012
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Chemoinformatic Identification of Novel Inhibitors against Mycobacterium tuberculosis L-aspartate a-decarboxylase
Wednesday, March 28, 2012
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Mesofluidic Devices for DNA-Programmed Combinatorial Chemistry
Thursday, March 29, 2012
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High Glucose Decreases Expression and Activity of p-glycoprotein in Cultured Human Retinal Pigment Epithelium Possibly through iNOS Induction
Friday, February 17, 2012
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Synthesis and Evaluation of a Series of 2-Substituted-5-Thiopropylpiperazine (Piperidine)-1,3,4-Oxadiazoles Derivatives as Atypical Antipsychotics
Monday, April 30, 2012
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Pharmacological Undertreatment of Coronary Risk Factors in Patients with Psoriasis: Observational Study of the Danish Nationwide Registries
Monday, April 30, 2012
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Treatment of Aspergillus fumigatus in Patients with Cystic Fibrosis: A Randomized, Placebo-Controlled Pilot Study
Monday, April 30, 2012
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Adult Neurogenesis Transiently Generates Oxidative Stress
Monday, April 30, 2012
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Antiproliferative Effects of DNA Methyltransferase 3B Depletion Are Not Associated with DNA Demethylation
Tuesday, May 01, 2012
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Ghrelin Treatment of Cachectic Patients with Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
Tuesday, May 01, 2012
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Vagal Nerve Stimulation Rapidly Activates Brain-Derived Neurotrophic Factor Receptor TrkB in Rat Brain
Tuesday, May 01, 2012
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Smooth Muscle Myosin Inhibition: A Novel Therapeutic Approach for Pulmonary Hypertension
Tuesday, May 01, 2012
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Antimalarial Activity and Mechanisms of Action of Two Novel 4-Aminoquinolines against Chloroquine-Resistant Parasites
Wednesday, May 23, 2012
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Interaction of Virstatin with Human Serum Albumin: Spectroscopic Analysis and Molecular Modeling
Wednesday, May 23, 2012
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Differences in Rat Dorsal Striatal NMDA and AMPA Receptors following Acute and Repeated Cocaine-Induced Locomotor Activation
Thursday, May 24, 2012
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Continuous Regional Arterial Infusion with Fluorouracil and Octreotide Attenuates Severe Acute Pancreatitis in a Canine Model
Thursday, May 24, 2012
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Impact of Obesity on the Bioavailability of Peginterferon-a2a and Ribavirin and Treatment Outcome for Chronic Hepatitis C Genotype 2 or 3
Thursday, May 24, 2012
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Nilotinib Counteracts P-Glycoprotein-Mediated Multidrug Resistance and Synergizes the Antitumoral Effect of Doxorubicin in Soft Tissue Sarcomas
Friday, May 25, 2012
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A Policy-into-Practice Intervention to Increase the Uptake of Evidence-Based Management of Low Back Pain in Primary Care: A Prospective Cohort Study
Friday, May 25, 2012
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Genotype-Dependent Efficacy of a Dual PI3K/mTOR Inhibitor, NVP-BEZ235, and an mTOR Inhibitor, RAD001, in Endometrial Carcinomas
Friday, May 25, 2012
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Pan-Pathway Based Interaction Profiling of FDA-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism
Friday, May 25, 2012
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Early Warning Indicators for HIV Drug Resistance in Cameroon during the Year 2010
Thursday, May 17, 2012
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Pemetrexed plus Platinum as the First-Line Treatment Option for Advanced Non-Small Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials
Thursday, May 17, 2012
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Atomic Force Mechanobiology of Pluripotent Stem Cell-Derived Cardiomyocytes
Friday, May 18, 2012
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Efficacious Intermittent Dosing of a Novel JAK2 Inhibitor in Mouse Models of Polycythemia Vera
Friday, May 18, 2012
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Patient Organizations’ Funding from Pharmaceutical Companies: Is Disclosure Clear, Complete and Accessible to the Public? An Italian Survey
Wednesday, May 09, 2012
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Malabaricone-A Induces A Redox Imbalance That Mediates Apoptosis in U937 Cell Line
Thursday, May 10, 2012
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Perifosine as a Potential Novel Anti-Cancer Agent Inhibits EGFR/MET-AKT Axis in Malignant Pleural Mesothelioma
Thursday, May 10, 2012
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Impact of Low-Level-Viremia on HIV-1 Drug-Resistance Evolution among Antiretroviral Treated-Patients
Thursday, May 10, 2012
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cGMP-Phosphodiesterase Inhibition Enhances Photic Responses and Synchronization of the Biological Circadian Clock in Rodents
Thursday, May 10, 2012
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Hydrogen Sulfide Inhibits L-Type Calcium Currents Depending upon the Protein Sulfhydryl State in Rat Cardiomyocytes
Thursday, May 10, 2012
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Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding
Friday, May 11, 2012
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Suppression of the Nrf2-Dependent Antioxidant Response by Glucocorticoids and 11ß-HSD1-Mediated Glucocorticoid Activation in Hepatic Cells
Friday, May 11, 2012
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Ginkgolide B Reduces Atherogenesis and Vascular Inflammation in ApoE-/- Mice
Friday, May 11, 2012
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The Effect of Ketoconazole on Post-Burn Inflammation, Hypermetabolism and Clinical Outcomes
Friday, May 11, 2012
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Induction of Cellular Senescence by Doxorubicin Is Associated with Upregulated miR-375 and Induction of Autophagy in K562 Cells
Friday, May 11, 2012
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Genetic Polymorphisms in CYP2E1: Association with Schizophrenia Susceptibility and Risperidone Response in the Chinese Han Population
Friday, May 11, 2012
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Mechanisms Underlying the Link between Cannabis Use and Prospective Memory
Friday, May 11, 2012
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Cluster Analysis of Obesity and Asthma Phenotypes
Friday, May 11, 2012
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Clonidine Improved Laboratory-Measured Decision-Making Performance in Abstinent Heroin Addicts
Monday, January 23, 2012
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In Vitro and In Vivo Investigation of the Efficacy of Arylimidamide DB1831 and Its Mesylated Salt Form - DB1965 - against Trypanosoma cruzi Infection
Monday, January 23, 2012
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Pregnane X Receptor and Yin Yang 1 Contribute to the Differential Tissue Expression and Induction of CYP3A5 and CYP3A4
Monday, January 23, 2012
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“Members of the Same Club”: Challenges and Decisions Faced by US IRBs in Identifying and Managing Conflicts of Interest
Friday, July 29, 2011
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Symptoms after Ingestion of Pig Whipworm Trichuris suis Eggs in a Randomized Placebo-Controlled Double-Blind Clinical Trial
Tuesday, August 02, 2011
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Pregnancy and Virologic Response to Antiretroviral Therapy in South Africa
Tuesday, August 02, 2011
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Anti-Inflammatory Effect of Fluvastatin on IL-8 Production Induced by Pseudomonas aeruginosa and Aspergillus fumigatus Antigens in Cystic Fibrosis
Wednesday, August 03, 2011
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Functional Categories Associated with Clusters of Genes That Are Co-Expressed across the NCI-60 Cancer Cell Lines
Tuesday, January 24, 2012
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Genome-Wide Association Study of Copy Number Variants Suggests LTBP1 and FGD4 Are Important for Alcohol Drinking
Wednesday, January 25, 2012
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Inhibition of Wnt/ß-Catenin Signaling by a Soluble Collagen-Derived Frizzled Domain Interacting with Wnt3a and the Receptors Frizzled 1 and 8
Friday, January 27, 2012
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ISL1 Directly Regulates FGF10 Transcription during Human Cardiac Outflow Formation
Friday, January 27, 2012
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Differential Role of PKC-Induced c-Jun in HTLV-1 LTR Activation by 12-O-Tetradecanoylphorbol-13-acetate in Different Human T-cell Lines
Friday, January 27, 2012
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Busulphan-Cyclophosphamide Cause Endothelial Injury, Remodeling of Resistance Arteries and Enhanced Expression of Endothelial Nitric Oxide Synthase
Friday, January 27, 2012
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Effects of a Selective Cannabinoid CB2 Agonist and Antagonist on Intravenous Nicotine Self Administration and Reinstatement of Nicotine Seeking
Thursday, January 26, 2012
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The Polyamine Inhibitor Alpha-Difluoromethylornithine Modulates Hippocampus-Dependent Function after Single and Combined Injuries
Friday, January 27, 2012
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Non-Host Defense Response in a Novel Arabidopsis-Xanthomonas citri subsp. citri Pathosystem
Friday, January 27, 2012
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Drosophila KCNQ Channel Displays Evolutionarily Conserved Electrophysiology and Pharmacology with Mammalian KCNQ Channels
Wednesday, September 07, 2011
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Increased Expression of Cannabinoid CB1 Receptors in Achilles Tendinosis
Thursday, September 08, 2011
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A Novel System for Transcutaneous Application of Carbon Dioxide Causing an “Artificial Bohr Effect” in the Human Body
Thursday, September 08, 2011
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Investigating the Effect of Emetic Compounds on Chemotaxis in Dictyostelium Identifies a Non-Sentient Model for Bitter and Hot Tastant Research
Thursday, September 08, 2011
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A Selectable and Excisable Marker System for the Rapid Creation of Recombinant Poxviruses
Thursday, September 08, 2011
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A Randomized, Placebo Controlled, Double Masked Phase IB Study Evaluating the Safety and Antiviral Activity of Aprepitant, a Neurokinin-1 Receptor Antagonist in HIV-1 Infected Adults
Thursday, September 08, 2011
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Donepezil Impairs Memory in Healthy Older Subjects: Behavioural, EEG and Simultaneous EEG/fMRI Biomarkers
Thursday, September 08, 2011
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Bioluminescence-Based High-Throughput Screen Identifies Pharmacological Agents That Target Neurotransmitter Signaling in Small Cell Lung Carcinoma
Thursday, September 08, 2011
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Hepatic Xenobiotic Metabolizing Enzyme and Transporter Gene Expression through the Life Stages of the Mouse
Thursday, September 08, 2011
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In vivo Bioimaging as a Novel Strategy to Detect Doxorubicin-Induced Damage to Gonadal Blood Vessels
Friday, September 09, 2011
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Calcineurin-Inhibitor Minimization in Liver Transplant Patients with Calcineurin-Inhibitor-Related Renal Dysfunction: A Meta-Analysis
Friday, September 09, 2011
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Calculation of Direct Antiretroviral Treatment Costs and Potential Cost Savings by Using Generics in the German HIV ClinSurv Cohort
Friday, September 09, 2011
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Opiate Sensitization Induces FosB/?FosB Expression in Prefrontal Cortical, Striatal and Amygdala Brain Regions
Tuesday, August 23, 2011
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BPR1K653, a Novel Aurora Kinase Inhibitor, Exhibits Potent Anti-Proliferative Activity in MDR1 (P-gp170)-Mediated Multidrug-Resistant Cancer Cells
Wednesday, August 24, 2011
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High Density Lipoprotein Structural Changes and Drug Response in Lipidomic Profiles following the Long-Term Fenofibrate Therapy in the FIELD Substudy
Wednesday, August 24, 2011
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The Impact of Illicit Drug Use on Spontaneous Hepatitis C Clearance: Experience from a Large Cohort Population Study
Wednesday, August 24, 2011
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Diphenyl Difluoroketone: A Potent Chemotherapy Candidate for Human Hepatocellular Carcinoma
Thursday, August 25, 2011
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Sodium/myo-Inositol Transporters: Substrate Transport Requirements and Regional Brain Expression in the TgCRND8 Mouse Model of Amyloid Pathology
Friday, August 26, 2011
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Is Nitric Oxide Decrease Observed with Naphthoquinones in LPS Stimulated RAW 264.7 Macrophages a Beneficial Property?
Friday, August 26, 2011
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Albiglutide, a Long Lasting Glucagon-Like Peptide-1 Analog, Protects the Rat Heart against Ischemia/Reperfusion Injury: Evidence for Improving Cardiac Metabolic Efficiency
Friday, August 26, 2011
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Mobilisation of Hematopoietic CD34+ Precursor Cells in Patients with Acute Stroke Is Safe - Results of an Open-Labeled Non Randomized Phase I/II Trial
Friday, August 26, 2011
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The Influence of Genetic and Environmental Factors among MDMA Users in Cognitive Performance
Wednesday, November 16, 2011
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Paternal Cyclophosphamide Exposure Induces the Formation of Functional Micronuclei during the First Zygotic Division
Wednesday, November 16, 2011
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Inotropic Action of the Puberty Hormone Kisspeptin in Rat, Mouse and Human: Cardiovascular Distribution and Characteristics of the Kisspeptin Receptor
Tuesday, November 22, 2011
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Anticoagulants and the Propagation Phase of Thrombin Generation
Friday, November 18, 2011
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Effects of DPP-4 Inhibitors on the Heart in a Rat Model of Uremic Cardiomyopathy
Friday, November 18, 2011
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Decreased Spontaneous Eye Blink Rates in Chronic Cannabis Users: Evidence for Striatal Cannabinoid-Dopamine Interactions
Friday, November 18, 2011
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Interaction between Dysfunctional Connectivity at Rest and Heroin Cues-Induced Brain Responses in Male Abstinent Heroin-Dependent Individuals
Tuesday, October 18, 2011
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Benefit from B-Lymphocyte Depletion Using the Anti-CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study
Wednesday, October 19, 2011
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A Multi-Compartment, Single and Multiple Dose Pharmacokinetic Study of the Vaginal Candidate Microbicide 1% Tenofovir Gel
Wednesday, October 19, 2011
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Cues Paired with either Rapid or Slower Self-Administered Cocaine Injections Acquire Similar Conditioned Rewarding Properties
Wednesday, October 19, 2011
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Rac1-Regulated Endothelial Radiation Response Stimulates Extravasation and Metastasis That Can Be Blocked by HMG-CoA Reductase Inhibitors
Wednesday, October 19, 2011
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Acaricide Residues in Laying Hens Naturally Infested by Red Mite Dermanyssus gallinae
Tuesday, February 21, 2012
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The Prevalence and Cost of Unapproved Uses of Top-Selling Orphan Drugs
Tuesday, February 21, 2012
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Therapeutic Trial of Metformin and Bortezomib in a Mouse Model of Tuberous Sclerosis Complex (TSC)
Tuesday, February 21, 2012
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Arsenic Trioxide Exerts Antimyeloma Effects by Inhibiting Activity in the Cytoplasmic Substrates of Histone Deacetylase 6
Wednesday, February 22, 2012
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Novel MUC1 Aptamer Selectively Delivers Cytotoxic Agent to Cancer Cells In Vitro
Wednesday, February 22, 2012
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Adenovirus-5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part B: Safety, Immunogenicity and Protective Efficacy of the CSP Component
Friday, October 07, 2011
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Adenovirus Gene Transfer to Amelogenesis Imperfecta Ameloblast-Like Cells
Friday, October 07, 2011
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Modeling Pharmacodynamic Response to the Poly(ADP-Ribose) Polymerase Inhibitor ABT-888 in Human Peripheral Blood Mononuclear Cells
Monday, October 10, 2011
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Cost-Effectiveness of Angiotensin-Converting Enzyme Inhibitors for the Prevention of Diabetic Nephropathy in The Netherlands – A Markov Model
Tuesday, October 11, 2011
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Correlation versus Causation? Pharmacovigilance of the Analgesic Flupirtine Exemplifies the Need for Refined Spontaneous ADR Reporting
Tuesday, October 11, 2011
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Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition
Wednesday, November 30, 2011
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Engineered Single-Domain Antibodies with High Protease Resistance and Thermal Stability
Wednesday, November 30, 2011
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Novel Inhibitor Design for Hemagglutinin against H1N1 Influenza Virus by Core Hopping Method
Wednesday, November 30, 2011
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Establishing Long-Term Efficacy in Chronic Disease: Use of Recursive Partitioning and Propensity Score Adjustment to Estimate Outcome in MS
Wednesday, November 30, 2011
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Smart Drugs “As Common As Coffee”: Media Hype about Neuroenhancement
Wednesday, November 30, 2011
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IL-4 Deficiency Is Associated with Mechanical Hypersensitivity in Mice
Friday, December 02, 2011
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Lucanthone and Its Derivative Hycanthone Inhibit Apurinic Endonuclease-1 (APE1) by Direct Protein Binding
Thursday, September 15, 2011
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Involvement of the Glycogen Synthase Kinase-3 Signaling Pathway in TBI Pathology and Neurocognitive Outcome
Thursday, September 15, 2011
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Natural Form of Noncytolytic Flexible Human Fc as a Long-Acting Carrier of Agonistic Ligand, Erythropoietin
Friday, September 16, 2011
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Metabolomics-Driven Nutraceutical Evaluation of Diverse Green Tea Cultivars
Wednesday, August 10, 2011
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Production of a Bioengineered G-Protein Coupled Receptor of Human Formyl Peptide Receptor 3
Thursday, August 11, 2011
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Optimal Control of Hepatitis C Antiviral Treatment Programme Delivery for Prevention amongst a Population of Injecting Drug Users
Thursday, August 11, 2011
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Mast Cells Are Critical for Protection against Peptic Ulcers Induced by the NSAID Piroxicam
Friday, August 12, 2011
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Morbidity from Malaria in Children in the Year after They Had Received Intermittent Preventive Treatment of Malaria: A Randomised Trial
Friday, August 12, 2011
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The Role of RamA on the Development of Ciprofloxacin Resistance in Salmonella enterica Serovar Typhimurium
Friday, August 12, 2011
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Discovery of Prostamide F2a and Its Role in Inflammatory Pain and Dorsal Horn Nociceptive Neuron Hyperexcitability
Tuesday, February 21, 2012
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Ephrin-A1-Mediated Dopaminergic Neurogenesis and Angiogenesis in a Rat Model of Parkinson's Disease
Monday, February 20, 2012
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Regulation of MMP-9 by a WIN-Binding Site in the Monocyte-Macrophage System Independent from Cannabinoid Receptors
Tuesday, November 06, 2012
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Sub-Inhibitory Cefsulodin Sensitization of E. coli to ß-lactams Is Mediated by PBP1b Inhibition
Tuesday, November 06, 2012
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Methamphetamine Reduces Human Influenza A Virus Replication
Tuesday, November 06, 2012
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Cardioprotective Effect of Paeonol and Danshensu Combination on Isoproterenol-Induced Myocardial Injury in Rats
Tuesday, November 06, 2012
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In Vitro and In Vivo Activity of an Organic Tellurium Compound on Leishmania (Leishmania) chagasi
Wednesday, November 07, 2012
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Enhanced Antitumor Efficacy and Reduced Systemic Toxicity of Sulfatide-Containing Nanoliposomal Doxorubicin in a Xenograft Model of Colorectal Cancer
Wednesday, November 07, 2012
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Caprylic Triglyceride as a Novel Therapeutic Approach to Effectively Improve the Performance and Attenuate the Symptoms Due to the Motor Neuron Loss in ALS Disease
Wednesday, November 07, 2012
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Lysosomotropic Properties of Weakly Basic Anticancer Agents Promote Cancer Cell Selectivity In Vitro
Wednesday, November 07, 2012
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Diminazene Aceturate (Berenil) Modulates the Host Cellular and Inflammatory Responses to Trypanosoma congolense Infection
Wednesday, November 07, 2012
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Artemisinin Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Inhibiting NF-?B Pathway in Microglia Cells
Friday, April 13, 2012
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Complement C1 Esterase Inhibitor Levels Linked to Infections and Contaminated Heparin-Associated Adverse Events
Friday, April 13, 2012
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Reaching the Hard-to-Reach: A Probability Sampling Method for Assessing Prevalence of Driving under the Influence after Drinking in Alcohol Outlets
Friday, April 13, 2012
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The Effect of Chronic Antipsychotic Drug on Hypothalamic Expression of Neural Nitric Oxide Synthase and Dopamine D2 Receptor in the Male Rat
Friday, April 13, 2012
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Loop Diuretics Have Anxiolytic Effects in Rat Models of Conditioned Anxiety
Friday, April 13, 2012
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Repeated Methamphetamine Administration Differentially Alters Fos Expression in Caudate-Putamen Patch and Matrix Compartments and Nucleus Accumbens
Friday, April 13, 2012
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Caffeine Consumption Prevents Diabetes-Induced Memory Impairment and Synaptotoxicity in the Hippocampus of NONcZNO10/LTJ Mice
Friday, April 13, 2012
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Interaction of Aspirin (Acetylsalicylic Acid) with Lipid Membranes
Tuesday, April 17, 2012
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Proteins from Avastin® (bevacizumab) Show Tyrosine Nitrations for which the Consequences Are Completely Unclear
Monday, April 16, 2012
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1,2-Octanediol, a Novel Surfactant, for Treating Head Louse Infestation: Identification of Activity, Formulation, and Randomised, Controlled Trials
Monday, April 16, 2012
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Adverse Events of Interferon Beta-1a: A Prospective Multi-Centre International ICH-GCP-Based CRO-Supported External Validation Study in Daily Practice
Tuesday, October 25, 2011
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Increasing Antiproliferative Properties of Endocannabinoids in N1E-115 Neuroblastoma Cells through Inhibition of Their Metabolism
Thursday, October 27, 2011
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Nebulisation of Receptor-Targeted Nanocomplexes for Gene Delivery to the Airway Epithelium
Wednesday, October 26, 2011
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Impact of Definitive Therapy with Beta-Lactam Monotherapy or Combination with an Aminoglycoside or a Quinolone for Pseudomonas aeruginosa Bacteremia
Wednesday, October 26, 2011
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Effects of Short-Term Continuous Subcutaneous Insulin Infusion on Fasting Plasma Fibroblast Growth Factor-21 Levels in Patients with Newly Diagnosed Type 2 Diabetes Mellitus
Wednesday, October 26, 2011
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Reversal of Fragile X Phenotypes by Manipulation of AßPP/Aß Levels in Fmr1KO Mice
Wednesday, October 26, 2011
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Protective Role of Hydrogen Sulfide against Noise-Induced Cochlear Damage: A Chronic Intracochlear Infusion Model
Wednesday, October 26, 2011
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Differential Effects of Accumbens Core vs. Shell Lesions in a Rat Concurrent Conditioned Place Preference Paradigm for Cocaine vs. Social Interaction
Wednesday, October 26, 2011
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Cost-Effectiveness of Pharmacotherapy to Reduce Obesity
Thursday, October 27, 2011
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Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27
Monday, October 31, 2011
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Nevirapine Plasma Concentrations Are Associated with Virologic Response and Hepatotoxicity in Chinese Patients with HIV Infection
Monday, October 31, 2011
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Differential Modulation of Beta-Adrenergic Receptor Signaling by Trace Amine-Associated Receptor 1 Agonists
Monday, October 31, 2011
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Vaccination of Lactating Dairy Cows for the Prevention of Aflatoxin B1 Carry Over in Milk
Friday, October 28, 2011
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Oleanolic Acid Initiates Apoptosis in Non-Small Cell Lung Cancer Cell Lines and Reduces Metastasis of a B16F10 Melanoma Model In Vivo
Friday, December 09, 2011
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Cochrane Systematic Reviews of Chinese Herbal Medicines: An Overview
Friday, December 09, 2011
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Development of Derivatives of 3, 3'-Diindolylmethane as Potent Leishmania donovani Bi-Subunit Topoisomerase IB Poisons
Monday, December 12, 2011
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Identifying HER2 Inhibitors from Natural Products Database
Monday, December 12, 2011
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Bisbibenzyls, a New Type of Antifungal Agent, Inhibit Morphogenesis Switch and Biofilm Formation through Upregulation of DPP3 in Candida albicans
Monday, December 12, 2011
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The Antidiabetic Drug Ciglitazone Induces High Grade Bladder Cancer Cells Apoptosis through the Up-Regulation of TRAIL
Monday, December 12, 2011
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In silico Analysis of Conformational Changes Induced by Mutation of Aromatic Binding Residues: Consequences for Drug Binding in the hERG K+ Channel
Thursday, December 15, 2011
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Checkpoint Signaling, Base Excision Repair, and PARP Promote Survival of Colon Cancer Cells Treated with 5-Fluorodeoxyuridine but Not 5-Fluorouracil
Thursday, December 15, 2011
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Antihypertensive Treatment Differentially Affects Vascular Sphingolipid Biology in Spontaneously Hypertensive Rats
Thursday, December 15, 2011
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Endemic Acinetobacter baumannii in a New York Hospital
Tuesday, December 13, 2011
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Additive Antinociceptive Effects of a Combination of Vitamin C and Vitamin E after Peripheral Nerve Injury
Wednesday, December 14, 2011
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A Novel Peptide Derived from Human Pancreatitis-Associated Protein Inhibits Inflammation In Vivo and In Vitro and Blocks NF-Kappa B Signaling Pathway
Wednesday, December 14, 2011
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Intraocular Pressure Changes: An Important Determinant of the Biocompatibility of Intravitreous Implants
Wednesday, December 14, 2011
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Thiopurine Methyltransferase Predicts the Extent of Cytotoxicty and DNA Damage in Astroglial Cells after Thioguanine Exposure
Wednesday, December 21, 2011
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Acid Solution Is a Suitable Medium for Introducing QX-314 into Nociceptors through TRPV1 Channels to Produce Sensory-Specific Analgesic Effects
Wednesday, December 28, 2011
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Differential Effects of Pravastatin and Simvastatin on the Growth of Tumor Cells from Different Organ Sites
Thursday, December 22, 2011
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Identification of New Alleles and the Determination of Alleles and Genotypes Frequencies at the CYP2D6 Gene in Emiratis
Thursday, December 22, 2011
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Safety of Postoperative Administration of Human Urinary Trypsin Inhibitor in Lung Cancer Patients with Idiopathic Pulmonary Fibrosis
Thursday, December 22, 2011
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Cardiovascular Agents Affect the Tone of Pulmonary Arteries and Veins in Precision-Cut Lung Slices
Tuesday, December 27, 2011
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Substance-Related Health Problems during Rave Parties in the Netherlands (1997–2008)
Wednesday, December 28, 2011
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Quality of Reporting of Bioequivalence Trials Comparing Generic to Brand Name Drugs: A Methodological Systematic Review
Wednesday, August 17, 2011
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Optimised and Rapid Pre-clinical Screening in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)
Thursday, August 18, 2011
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The Astrocyte-Targeted Therapy by Bushi for the Neuropathic Pain in Mice
Thursday, August 18, 2011
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Functional Insight into the C-Terminal Extension of Halolysin SptA from Haloarchaeon Natrinema sp. J7
Friday, August 19, 2011
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Pilot, Randomized Study Assessing Safety, Tolerability and Efficacy of Simplified LPV/r Maintenance Therapy in HIV Patients on the 1st PI-Based Regimen
Friday, August 19, 2011
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Molecular Sites for the Positive Allosteric Modulation of Glycine Receptors by Endocannabinoids
Thursday, August 25, 2011
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Comprehensive Study in the Inhibitory Effect of Berberine on Gene Transcription, Including TATA Box
Monday, August 22, 2011
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A Pilot Randomised Trial of Induced Blood-Stage Plasmodium falciparum Infections in Healthy Volunteers for Testing Efficacy of New Antimalarial Drugs
Monday, August 22, 2011
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Curcumin-Loaded Apotransferrin Nanoparticles Provide Efficient Cellular Uptake and Effectively Inhibit HIV-1 Replication In Vitro
Monday, August 22, 2011
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Novel Binding Mode of a Potent and Selective Tankyrase Inhibitor
Friday, March 16, 2012
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Reversal of Cocaine-Conditioned Place Preference through Methyl Supplementation in Mice: Altering Global DNA Methylation in the Prefrontal Cortex
Friday, March 16, 2012
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Enhanced Interleukin-1 Activity Contributes to Exercise Intolerance in Patients with Systolic Heart Failure
Friday, March 16, 2012
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Prediction of Promiscuous P-Glycoprotein Inhibition Using a Novel Machine Learning Scheme
Friday, March 16, 2012
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Quantitative Proteome Profiling of C. burnetii under Tetracycline Stress Conditions
Friday, March 16, 2012
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Down-Regulation of Glucose-Regulated Protein (GRP) 78 Potentiates Cytotoxic Effect of Celecoxib in Human Urothelial Carcinoma Cells
Friday, March 16, 2012
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Investigation of Indazole Unbinding Pathways in CYP2E1 by Molecular Dynamics Simulations
Monday, March 19, 2012
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Moderate Antiproteinuric Effect of Add-On Aldosterone Blockade with Eplerenone in Non-Diabetic Chronic Kidney Disease. A Randomized Cross-Over Study
Friday, November 04, 2011
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Effects of Vitamin D Supplementation on Cognitive and Emotional Functioning in Young Adults – A Randomised Controlled Trial
Friday, November 04, 2011
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Regional Grey and White Matter Changes in Heavy Male Smokers
Friday, November 04, 2011
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Metabolic Patterns and Biotransformation Activities of Resveratrol in Human Glioblastoma Cells: Relevance with Therapeutic Efficacies
Friday, November 11, 2011
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A Novel, Functional and Replicable Risk Gene Region for Alcohol Dependence Identified by Genome-Wide Association Study
Monday, November 07, 2011
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Suppression of Expression of Heat Shock Protein 70 by Gefitinib and Its Contribution to Pulmonary Fibrosis
Wednesday, November 09, 2011
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Everolimus and Sirolimus in Combination with Cyclosporine Have Different Effects on Renal Metabolism in the Rat
Wednesday, October 31, 2012
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A Phage Display Selected 7-mer Peptide Inhibitor of the Tannerella forsythia Metalloprotease-Like Enzyme Karilysin can be Truncated to Ser-Trp-Phe-Pro
Wednesday, October 31, 2012
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Targeting 3-Phosphoinoside-Dependent Kinase-1 to Inhibit Insulin-Like Growth Factor-I Induced AKT and p70 S6 Kinase Activation in Breast Cancer Cells
Wednesday, October 31, 2012
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Modeling 18F-FDG Kinetics during Acute Lung Injury: Experimental Data and Estimation Errors
Wednesday, October 31, 2012
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Scaffold-Based Pan-Agonist Design for the PPARa, PPARß and PPAR? Receptors
Wednesday, October 31, 2012
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Clinical Presentations, Antiplatelet Strategies and Prognosis of Patients with Stent Thrombosis: An Observational Study of 140 Patients
Wednesday, October 31, 2012
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In Vivo and In Vitro Suppression of Hepatocellular Carcinoma by EF24, a Curcumin Analog
Wednesday, October 31, 2012
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Alcohol Affects the Brain's Resting-State Network in Social Drinkers
Wednesday, October 31, 2012
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Comparison of Suprachoroidal Drug Delivery with Subconjunctival and Intravitreal Routes Using Noninvasive Fluorophotometry
Wednesday, October 31, 2012
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H1-Antihistamine Up-Dosing in Chronic Spontaneous Urticaria: Patients' Perspective of Effectiveness and Side Effects – A Retrospective Survey Study
Thursday, September 01, 2011
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Enhanced Transferrin Receptor Expression by Proinflammatory Cytokines in Enterocytes as a Means for Local Delivery of Drugs to Inflamed Gut Mucosa
Tuesday, September 06, 2011
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Hepatotoxicity or Hepatoprotection? Pattern Recognition for the Paradoxical Effect of the Chinese Herb Rheum palmatum L. in Treating Rat Liver Injury
Tuesday, September 06, 2011
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Effects and Action Mechanisms of Berberine and Rhizoma coptidis on Gut Microbes and Obesity in High-Fat Diet-Fed C57BL/6J Mice
Tuesday, September 06, 2011
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Multicenter Phase 2 Trial of Sirolimus for Tuberous Sclerosis: Kidney Angiomyolipomas and Other Tumors Regress and VEGF- D Levels Decrease
Tuesday, September 06, 2011
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Meta-Analysis of the Immunogenicity and Tolerability of Pandemic Influenza A 2009 (H1N1) Vaccines
Tuesday, September 06, 2011
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Sustained Release of an Anti-Glaucoma Drug: Demonstration of Efficacy of a Liposomal Formulation in the Rabbit Eye
Friday, September 09, 2011
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Gene Expression Signature Analysis Identifies Vorinostat as a Candidate Therapy for Gastric Cancer
Friday, September 09, 2011
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Association between Single Nucleotide Polymorphisms (SNPs) and Toxicity of Advanced Non-Small-Cell Lung Cancer Patients Treated with Chemotherapy
Wednesday, October 31, 2012
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Total Beta-Adrenoceptor Knockout Slows Conduction and Reduces Inducible Arrhythmias in the Mouse Heart
Thursday, November 01, 2012
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Variants Identified in a GWAS Meta-Analysis for Blood Lipids Are Associated with the Lipid Response to Fenofibrate
Wednesday, October 31, 2012
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Pioglitazone Improves In Vitro Viability and Function of Endothelial Progenitor Cells from Individuals with Impaired Glucose Tolerance
Monday, November 05, 2012
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Pharmacogenetics of Efficacy and Safety of HCV Treatment in HCV-HIV Coinfected Patients: Significant Associations with IL28B and SOCS3 Gene Variants
Friday, November 02, 2012
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Sigma-1 Receptor Agonists Directly Inhibit NaV1.2/1.4 Channels
Monday, November 05, 2012
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Identification of Novel HIV 1- Protease Inhibitors: Application of Ligand and Structure Based Pharmacophore Mapping and Virtual Screening
Thursday, November 08, 2012
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The Nonantibiotic Small Molecule Cyslabdan Enhances the Potency of ß-Lactams against MRSA by Inhibiting Pentaglycine Interpeptide Bridge Synthesis
Tuesday, November 06, 2012
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Efficacy of Single-Dose and Triple-Dose Albendazole and Mebendazole against Soil-Transmitted Helminths and Taenia spp.: A Randomized Controlled Trial
Tuesday, September 27, 2011
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Prenatal Cocaine Exposure Increases Synaptic Localization of a Neuronal RasGEF, GRASP-1 via Hyperphosphorylation of AMPAR Anchoring Protein, GRIP
Tuesday, September 27, 2011
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Synergistic Inhibition of Endothelial Cell Proliferation, Tube Formation, and Sprouting by Cyclosporin A and Itraconazole
Wednesday, September 28, 2011
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Atorvastatin Therapy during the Peri-Infarct Period Attenuates Left Ventricular Dysfunction and Remodeling after Myocardial Infarction
Wednesday, September 28, 2011
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Reversible Resistance Induced by FLT3 Inhibition: A Novel Resistance Mechanism in Mutant FLT3-Expressing Cells
Wednesday, September 28, 2011
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Enrollment Characteristics and Risk Behaviors of Injection Drug Users Participating in the Bangkok Tenofovir Study, Thailand
Wednesday, September 28, 2011
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High-Throughput Screen for Identifying Small Molecules That Target Fungal Zinc Homeostasis
Thursday, September 29, 2011
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The Novel Gamma Secretase Inhibitor RO4929097 Reduces the Tumor Initiating Potential of Melanoma
Thursday, September 29, 2011
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Disease Severity and Progression in Progressive Supranuclear Palsy and Multiple System Atrophy: Validation of the NNIPPS – PARKINSON PLUS SCALE
Thursday, August 04, 2011
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Adverse Events Following Pandemic A (H1N1) 2009 Monovalent Vaccines in Pregnant Women — Taiwan, November 2009–August 2010
Friday, August 05, 2011
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Mytilus galloprovincialis Myticin C: A Chemotactic Molecule with Antiviral Activity and Immunoregulatory Properties
Monday, August 08, 2011
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Treatment Interruption and Variation in Tablet Taking Behaviour Result in Viral Failure: A Case-Control Study from Cape Town, South Africa
Monday, August 08, 2011
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A Double Blind, Placebo-Controlled, Randomized Crossover Study of the Acute Metabolic Effects of Olanzapine in Healthy Volunteers
Tuesday, August 09, 2011
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Anti-Angiogenic and Anti-Inflammatory Properties of Kahweol, a Coffee Diterpene
Tuesday, August 09, 2011
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The Effect of the Potential PhoQ Histidine Kinase Inhibitors on Shigella flexneri Virulence
Wednesday, August 10, 2011
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BTZO-15, an ARE-Activator, Ameliorates DSS- and TNBS-Induced Colitis in Rats
Wednesday, August 10, 2011
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Implication of Glutathione in the In Vitro Antiplasmodial Mechanism of Action of Ellagic Acid
Friday, September 28, 2012
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H(2)S-Releasing Aspirin Protects against Aspirin-Induced Gastric Injury via Reducing Oxidative Stress
Friday, September 28, 2012
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Protective Effects of Polydatin from Polygonum cuspidatum against Carbon Tetrachloride-Induced Liver Injury in Mice
Friday, September 28, 2012
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LXR-Mediated Inhibition of CD4+ T Helper Cells
Friday, September 28, 2012
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Study of Natural Health Product Adverse Reactions (SONAR): Active Surveillance of Adverse Events Following Concurrent Natural Health Product and Prescription Drug Use in Community Pharmacies
Friday, September 28, 2012
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Comparison of Optical and Power Doppler Ultrasound Imaging for Non-Invasive Evaluation of Arsenic Trioxide as a Vascular Disrupting Agent in Tumors
Friday, September 28, 2012
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AZD1480 Blocks Growth and Tumorigenesis of RET- Activated Thyroid Cancer Cell Lines
Tuesday, October 02, 2012
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Select Small Core Structure Carbamates Exhibit High Contact Toxicity to “Carbamate-Resistant” Strain Malaria Mosquitoes, Anopheles gambiae (Akron)
Monday, October 01, 2012
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Recombinant Adiponectin Does Not Lower Plasma Glucose in Animal Models of Type 2 Diabetes
Monday, October 01, 2012
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Maximal Load of the Vitamin B12 Transport System: A Study on Mice Treated for Four Weeks with High-Dose Vitamin B12 or Cobinamide
Monday, October 01, 2012
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A Systems Approach for Tumor Pharmacokinetics
Wednesday, September 14, 2011
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MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma
Monday, September 12, 2011
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Environmental Levels of the Antiviral Oseltamivir Induce Development of Resistance Mutation H274Y in Influenza A/H1N1 Virus in Mallards
Monday, September 12, 2011
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Cilostazol Activates Function of Bone Marrow-Derived Endothelial Progenitor Cell for Re-endothelialization in a Carotid Balloon Injury Model
Monday, September 12, 2011
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In Vitro Evolution of Allergy Vaccine Candidates, with Maintained Structure, but Reduced B Cell and T Cell Activation Capacity
Tuesday, September 13, 2011
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Styryl-Based and Tricyclic Compounds as Potential Anti-Prion Agents
Tuesday, September 13, 2011
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Statins Enhance Clonal Growth of Late Outgrowth Endothelial Progenitors and Increase Myocardial Capillary Density in the Chronically Ischemic Heart
Tuesday, September 13, 2011
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Immunosuppressive Treatment for Nephrotic Idiopathic Membranous Nephropathy: A Meta-Analysis Based on Chinese Adults
Wednesday, September 05, 2012
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Towards Measuring Brain Function on Groups of People in the Real World
Wednesday, September 05, 2012
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Differential Effects of Short-Term Treatment with Two AT1 Receptor Blockers on Diameter of Pial Arterioles in SHR
Wednesday, September 05, 2012
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Phototriggerable 2',7-Caged Paclitaxel
Thursday, September 06, 2012
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Docosahexaenoic Acid for Reading, Cognition and Behavior in Children Aged 7–9 Years: A Randomized, Controlled Trial (The DOLAB Study)
Thursday, September 06, 2012
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SU5416, a VEGF Receptor Inhibitor and Ligand of the AHR, Represents a New Alternative for Immunomodulation
Thursday, September 06, 2012
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Development of Multicellular Tumor Spheroid (MCTS) Culture from Breast Cancer Cell and a High Throughput Screening Method Using the MTT Assay
Thursday, September 06, 2012
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Safety and Tolerability of Lactobacillus reuteri DSM 17938 and Effects on Biomarkers in Healthy Adults: Results from a Randomized Masked Trial
Thursday, September 06, 2012
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Bone Marrow-Derived Mesenchymal Stem Cells Repaired but Did Not Prevent Gentamicin-Induced Acute Kidney Injury through Paracrine Effects in Rats
Thursday, September 06, 2012
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a-Tomatine-Mediated Anti-Cancer Activity In Vitro and In Vivo through Cell Cycle- and Caspase-Independent Pathways
Thursday, September 06, 2012
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Identification of PPARgamma Partial Agonists of Natural Origin (I): Development of a Virtual Screening Procedure and In Vitro Validation
Friday, November 30, 2012
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Discovery of a Novel, Monocationic, Small-Molecule Inhibitor of Scrapie Prion Accumulation in Cultured Sheep Microglia and Rov Cells
Friday, November 30, 2012
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Nicotine Reward and Affective Nicotine Withdrawal Signs Are Attenuated in Calcium/Calmodulin-Dependent Protein Kinase IV Knockout Mice
Friday, November 30, 2012
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Lipid-Lowering Effects of Tetradecylthioacetic Acid in Antipsychotic-Exposed, Female Rats: Challenges with Long-Term Treatment
Friday, November 30, 2012
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Impact of Individual and Environmental Socioeconomic Status on Peritoneal Dialysis Outcomes: A Retrospective Multicenter Cohort Study
Friday, November 30, 2012
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Evaluation of Peripheral Blood Mononuclear Cell Processing and Analysis for Survival Motor Neuron Protein
Friday, November 30, 2012
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Functional Analysis of Plasmodium vivax Dihydrofolate Reductase-Thymidylate Synthase Genes through Stable Transformation of Plasmodium falciparum
Monday, July 09, 2012
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The Loss of Metabolic Control on Alcohol Drinking in Heavy Drinking Alcohol-Dependent Subjects
Monday, July 09, 2012
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The Interplay of Lung Surfactant Proteins and Lipids Assimilates the Macrophage Clearance of Nanoparticles
Tuesday, July 10, 2012
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Cold Storage of Rat Hepatocyte Suspensions for One Week in a Customized Cold Storage Solution – Preservation of Cell Attachment and Metabolism
Monday, July 09, 2012
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Capture, Anesthesia, and Disturbance of Free-Ranging Brown Bears (Ursus arctos) during Hibernation
Monday, July 16, 2012
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Systems Biological Approach of Molecular Descriptors Connectivity: Optimal Descriptors for Oral Bioavailability Prediction
Monday, July 16, 2012
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Prediction of Chemical-Protein Interactions Network with Weighted Network-Based Inference Method
Monday, July 16, 2012
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Tamoxifen-Induced Epigenetic Silencing of Oestrogen-Regulated Genes in Anti-Hormone Resistant Breast Cancer
Tuesday, July 10, 2012
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A Novel Flow Cytometric HTS Assay Reveals Functional Modulators of ATP Binding Cassette Transporter ABCB6
Tuesday, July 10, 2012
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Splicing of the rSlo Gene Affects the Molecular Composition and Drug Response of Ca2+-Activated K+ Channels in Skeletal Muscle
Tuesday, July 10, 2012
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Inactivation of Candida Biofilms by Non-Thermal Plasma and Its Enhancement for Fungistatic Effect of Antifungal Drugs
Tuesday, July 10, 2012
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Effects of Acute MDMA Intoxication on Mood and Impulsivity: Role of the 5-HT2 and 5-HT1 Receptors
Tuesday, July 10, 2012
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Crowd Sourcing a New Paradigm for Interactome Driven Drug Target Identification in Mycobacterium tuberculosis
Wednesday, July 11, 2012
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Energetics of Ortho-7 (Oxime Drug) Translocation through the Active-Site Gorge of Tabun Conjugated Acetylcholinesterase
Wednesday, July 11, 2012
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Hydrogen Sulfide Suppresses Outward Rectifier Potassium Currents in Human Pluripotent Stem Cell-Derived Cardiomyocytes
Friday, November 30, 2012
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Withaferin A Induces Proteasome Inhibition, Endoplasmic Reticulum Stress, the Heat Shock Response and Acquisition of Thermotolerance
Friday, November 30, 2012
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Synergistic Action of Gentamicin and Bacteriophage in a Continuous Culture Population of Staphylococcus aureus
Friday, November 30, 2012
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2, 3, 5, 4'-Tetrahydroxystilbene-2-O-Beta-D-Glucoside Improves Gastrointestinal Motility Disorders in STZ-Induced Diabetic Mice
Monday, December 03, 2012
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Human Monoclonal Antibodies against Glucagon Receptor Improve Glucose Homeostasis by Suppression of Hepatic Glucose Output in Diet-Induced Obese Mice
Monday, December 03, 2012
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Extract of Kuding Tea Prevents High-Fat Diet-Induced Metabolic Disorders in C57BL/6 Mice via Liver X Receptor (LXR) ß Antagonism
Tuesday, December 04, 2012
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Development of a Novel DNA Aptamer Ligand Targeting to Primary Cultured Tumor Endothelial Cells by a Cell-Based SELEX Method
Tuesday, December 04, 2012
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Willingness to Participate in HIV Vaccine Trials among Men Who Have Sex with Men in Chennai and Mumbai, India: A Social Ecological Approach
Tuesday, December 04, 2012
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Prevention of Vaginal SHIV Transmission in Macaques by a Coitally-Dependent Truvada Regimen
Tuesday, December 04, 2012
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Antipsychotic-Induced Movement Disorders in Long-Stay Psychiatric Patients and 45 Tag SNPs in 7 Candidate Genes: A Prospective Study
Tuesday, December 04, 2012
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Cost-Effectiveness of Buprenorphine and Naltrexone Treatments for Heroin Dependence in Malaysia
Tuesday, December 04, 2012
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Adverse Drug Reactions Causing Admission to a Paediatric Hospital
Tuesday, December 04, 2012
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Local Arginase Inhibition during Early Reperfusion Mediates Cardioprotection via Increased Nitric Oxide Production
Tuesday, July 31, 2012
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Aciculatin Inhibits Granulocyte Colony-Stimulating Factor Production by Human Interleukin 1ß-Stimulated Fibroblast-Like Synoviocytes
Tuesday, July 31, 2012
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Differential Trypanocidal Activity of Novel Macrolide Antibiotics; Correlation to Genetic Lineage
Tuesday, July 31, 2012
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Beneficial Effects on Arterial Stiffness and Pulse-Wave Reflection of Combined Enalapril and Candesartan in Chronic Kidney Disease - A Randomized Trial
Tuesday, July 31, 2012
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An Induced Pocket for the Binding of Potent Fusion Inhibitor CL-385319 with H5N1 Influenza Virus Hemagglutinin
Thursday, August 02, 2012
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Effectiveness and Cost-Effectiveness of Antidepressants in Primary Care: A Multiple Treatment Comparison Meta-Analysis and Cost-Effectiveness Model
Thursday, August 02, 2012
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Solvent Free Fabrication of Micro and Nanostructured Drug Coatings by Thermal Evaporation for Controlled Release and Increased Effects
Wednesday, August 01, 2012
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Antitumor Activity of Emodin against Pancreatic Cancer Depends on Its Dual Role: Promotion of Apoptosis and Suppression of Angiogenesis
Thursday, August 02, 2012
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Long Term Stabilization of Expanding Aortic Aneurysms by a Short Course of Cyclosporine A through Transforming Growth Factor-Beta Induction
Wednesday, December 14, 2011
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Development and Inter-Rater Reliability of the Liverpool Adverse Drug Reaction Causality Assessment Tool
Wednesday, December 14, 2011
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Learning and Memory Alterations Are Associated with Hippocampal N-acetylaspartate in a Rat Model of Depression as Measured by 1H-MRS
Wednesday, December 14, 2011
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Inhibition of Influenza A Virus (H1N1) Fusion by Benzenesulfonamide Derivatives Targeting Viral Hemagglutinin
Thursday, December 15, 2011
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Statin-Associated Muscular and Renal Adverse Events: Data Mining of the Public Version of the FDA Adverse Event Reporting System
Tuesday, December 20, 2011
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Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer, Inhibits Amyloid-ß-Mediated Alzheimer's Disease-Associated Pathogenesis In Vitro and In Vivo
Thursday, February 23, 2012
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P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action
Thursday, February 23, 2012
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Exendin-4 Ameliorates Motor Neuron Degeneration in Cellular and Animal Models of Amyotrophic Lateral Sclerosis
Thursday, February 23, 2012
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Genome Wide Adaptations of Plasmodium falciparum in Response to Lumefantrine Selective Drug Pressure
Monday, February 27, 2012
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Serotonin Antagonism Improves Platelet Inhibition in Clopidogrel Low-Responders after Coronary Stent Placement: An In Vitro Pilot Study
Monday, February 27, 2012
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Development and Validation of an Automated High-Throughput System for Zebrafish In Vivo Screenings
Tuesday, May 15, 2012
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Examining the Interactome of Huperzine A by Magnetic Biopanning
Wednesday, May 16, 2012
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Influence of Neonatal Hypothyroidism on Hepatic Gene Expression and Lipid Metabolism in Adulthood
Wednesday, May 16, 2012
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The Risk of Amenorrhea Is Related to Chemotherapy-Induced Leucopenia in Breast Cancer Patients Receiving Epirubicin and Taxane Based Chemotherapy
Wednesday, May 16, 2012
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Tetrahydrouridine Inhibits Cell Proliferation through Cell Cycle Regulation Regardless of Cytidine Deaminase Expression Levels
Wednesday, May 16, 2012
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Adherence to Interferon ß-1b Treatment in Patients with Multiple Sclerosis in Spain
Wednesday, May 16, 2012
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Association of Typical versus Atypical Antipsychotics with Symptoms and Quality of Life in Schizophrenia
Wednesday, May 16, 2012
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Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound
Friday, May 18, 2012
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Responses to Dehydration in the One-Humped Camel and Effects of Blocking the Renin-Angiotensin System
Friday, May 18, 2012
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Neuronatin in a Subset of Glioblastoma Multiforme Tumor Progenitor Cells Is Associated with Increased Cell Proliferation and Shorter Patient Survival
Friday, May 18, 2012
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The JNK Inhibitor XG-102 Protects against TNBS-Induced Colitis
Tuesday, March 13, 2012
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Dendrimers Bind Antioxidant Polyphenols and cisPlatin Drug
Tuesday, March 13, 2012
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Effects of Anesthetic Agents on Brain Blood Oxygenation Level Revealed with Ultra-High Field MRI
Monday, March 12, 2012
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Common Changes in Global Gene Expression Induced by RNA Polymerase Inhibitors in shigella flexneri
Monday, March 12, 2012
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Blocking Autophagy Prevents Bortezomib-Induced NF-?B Activation by Reducing I-?Ba Degradation in Lymphoma Cells
Wednesday, February 29, 2012
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Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model
Thursday, March 01, 2012
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Identification of the Neogenin-Binding Site on the Repulsive Guidance Molecule A
Thursday, March 01, 2012
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Effects of S-Propargyl-Cysteine (SPRC) in Caerulein-Induced Acute Pancreatitis in Mice
Thursday, March 01, 2012
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Is Opium a Real Risk Factor for Esophageal Cancer or Just a Methodological Artifact? Hospital and Neighborhood Controls in Case-Control Studies
Thursday, March 01, 2012
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Flavonoid Glycosides Isolated from Unique Legume Plant Extracts as Novel Inhibitors of Xanthine Oxidase
Friday, March 02, 2012
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Synthesis of a Dual Functional Anti-MDR Tumor Agent PH II-7 with Elucidations of Anti-Tumor Effects and Mechanisms
Monday, March 05, 2012
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Exploring DNA Topoisomerase I Ligand Space in Search of Novel Anticancer Agents
Thursday, September 22, 2011
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Acute Effects of Nicotine Amplify Accumbal Neural Responses during Nicotine-Taking Behavior and Nicotine-Paired Environmental Cues
Thursday, September 22, 2011
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Global Inhibition of Reactive Oxygen Species (ROS) Inhibits Paclitaxel-Induced Painful Peripheral Neuropathy
Monday, September 26, 2011
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HIV Protease Inhibitors Act as Competitive Inhibitors of the Cytoplasmic Glucose Binding Site of GLUTs with Differing Affinities for GLUT1 and GLUT4
Friday, September 23, 2011
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Effect of Hydrogen Peroxide and Superoxide Anions on Cytosolic Ca2+: Comparison of Endothelial Cells from Large-Sized and Small-Sized Arteries
Monday, September 26, 2011
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Five-Year Prognosis in an Incident Cohort of People Presenting with Acute Myocardial Infarction
Thursday, October 20, 2011
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Identification of Direct Target Engagement Biomarkers for Kinase-Targeted Therapeutics
Monday, October 24, 2011
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The Antinociceptive Effects of JWH-015 in Chronic Inflammatory Pain Are Produced by Nitric Oxide-cGMP-PKG-KATP Pathway Activation Mediated by Opioids
Friday, October 21, 2011
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Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37
Friday, October 21, 2011
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Use of Recombinant Adenovirus Vectored Consensus IFN-a to Avert Severe Arenavirus Infection
Monday, October 24, 2011
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A Thiopurine Drug Inhibits West Nile Virus Production in Cell Culture, but Not in Mice
Monday, October 24, 2011
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Inhibition of hERG Potassium Channels by Celecoxib and Its Mechanism
Monday, October 24, 2011
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S-diclofenac Protects against Doxorubicin-Induced Cardiomyopathy in Mice via Ameliorating Cardiac Gap Junction Remodeling
Monday, October 24, 2011
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Protective Effects of White Button Mushroom (Agaricus bisporus) against Hepatic Steatosis in Ovariectomized Mice as a Model of Postmenopausal Women
Tuesday, October 25, 2011
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Elderly Subjects Have a Delayed Antibody Response and Prolonged Viraemia following Yellow Fever Vaccination: A Prospective Controlled Cohort Study
Wednesday, December 07, 2011
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Prescribing Trends in Bipolar Disorder: Cohort Study in the United Kingdom THIN Primary Care Database 1995–2009
Wednesday, December 07, 2011
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Pleiotropic Benefit of Monomeric and Oligomeric Flavanols on Vascular Health - A Randomized Controlled Clinical Pilot Study
Thursday, December 08, 2011
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Dexamethasone and Long-Term Outcome of Tuberculous Meningitis in Vietnamese Adults and Adolescents
Thursday, December 08, 2011
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Characterization of Pellicle Inhibition in Gluconacetobacter xylinus 53582 by a Small Molecule, Pellicin, Identified by a Chemical Genetics Screen
Friday, December 09, 2011
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Surveillance of Broad-Spectrum Antibiotic Prescription in Singaporean Hospitals: A 5-Year Longitudinal Study
Friday, December 09, 2011
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Structure-Based Development of Small Molecule PFKFB3 Inhibitors: A Framework for Potential Cancer Therapeutic Agents Targeting the Warburg Effect
Wednesday, September 21, 2011
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Incidence and Severity of Coronary Artery Disease in Patients with Atrial Fibrillation Undergoing First-Time Coronary Angiography
Wednesday, September 21, 2011
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Comparison of the Safety and Pharmacokinetics of ST-246® after IV Infusion or Oral Administration in Mice, Rabbits and Monkeys
Monday, August 15, 2011
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Dopaminergic and Serotonergic Drug Use: A Nationwide Register-Based Study of Over 1 300 000 Older People
Monday, August 15, 2011
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Modeling HIV/AIDS Drug Price Determinants in Brazil: Is Generic Competition a Myth?
Monday, August 15, 2011
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Role of Novelty Seeking Personality Traits as Mediator of the Association between COMT and Onset Age of Drug Use in Chinese Heroin Dependent Patients
Wednesday, August 17, 2011
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Permeation through the Cell Membrane of a Boron-Based ß-Lactamase Inhibitor
Wednesday, August 17, 2011
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Targeting of T/Tn Antigens with a Plant Lectin to Kill Human Leukemia Cells by Photochemotherapy
Wednesday, August 17, 2011
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Probing the Interaction of the Diarylquinoline TMC207 with Its Target Mycobacterial ATP Synthase
Wednesday, August 17, 2011
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Fluorescence Dequenching Makes Haem-Free Soluble Guanylate Cyclase Detectable in Living Cells
Wednesday, August 17, 2011
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Real Time Enzyme Inhibition Assays Provide Insights into Differences in Binding of Neuraminidase Inhibitors to Wild Type and Mutant Influenza Viruses
Wednesday, August 17, 2011
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Bothrops jararaca Peptide with Anti-Hypertensive Action Normalizes Endothelium Dysfunction Involved in Physiopathology of Preeclampsia
Wednesday, August 17, 2011
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Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome
Wednesday, August 17, 2011
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Adherence of Pharmaceutical Advertisements in Medical Journals to FDA Guidelines and Content for Safe Prescribing
Wednesday, August 17, 2011
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Autoluminescent Mycobacterium tuberculosis for Rapid, Real-Time, Non-Invasive Assessment of Drug and Vaccine Efficacy
Wednesday, January 11, 2012
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Mitochondrial Electron Transport Is the Cellular Target of the Oncology Drug Elesclomol
Wednesday, January 11, 2012
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The Protein Kinase C Inhibitor Enzastaurin Exhibits Antitumor Activity against Uveal Melanoma
Thursday, January 12, 2012
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Granulocyte-Colony Stimulating Factor (G-CSF) Improves Motor Recovery in the Rat Impactor Model for Spinal Cord Injury
Thursday, January 12, 2012
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GABAergic Gene Expression in Postmortem Hippocampus from Alcoholics and Cocaine Addicts; Corresponding Findings in Alcohol-Naïve P and NP Rats
Friday, January 13, 2012
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Intestinal Absorption and First-Pass Metabolism of Polyphenol Compounds in Rat and Their Transport Dynamics in Caco-2 Cells
Friday, January 13, 2012
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Modularity in Protein Complex and Drug Interactions Reveals New Polypharmacological Properties
Wednesday, January 18, 2012
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Novel Bacterial Metabolite Merochlorin A Demonstrates in vitro Activity against Multi-Drug Resistant Methicillin-Resistant Staphylococcus aureus
Wednesday, January 18, 2012
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Wogonin Improves Histological and Functional Outcomes, and Reduces Activation of TLR4/NF-?B Signaling after Experimental Traumatic Brain Injury
Tuesday, January 17, 2012
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Bone Mineral Density in HIV-Negative Men Participating in a Tenofovir Pre-Exposure Prophylaxis Randomized Clinical Trial in San Francisco
Monday, August 29, 2011
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Evaluation of Two Models for Human Topoisomerase I Interaction with dsDNA and Camptothecin Derivatives
Tuesday, August 30, 2011
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Direct Semi-Synthesis of the Anticancer Lead-Drug Protoapigenone from Apigenin, and Synthesis of Further New Cytotoxic Protoflavone Derivatives
Tuesday, August 30, 2011
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Allopregnanolone Promotes Regeneration and Reduces ß-Amyloid Burden in a Preclinical Model of Alzheimer's Disease
Tuesday, August 30, 2011
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Studies on the Antibacterial Effects of Statins - In Vitro and In Vivo
Tuesday, August 30, 2011
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Metformin Treatment Has No Beneficial Effect in a Dose-Response Survival Study in the SOD1G93A Mouse Model of ALS and Is Harmful in Female Mice
Thursday, September 01, 2011
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High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model
Wednesday, August 31, 2011
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Identification of Novel Functional Inhibitors of Acid Sphingomyelinase
Wednesday, August 31, 2011
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Dietary a-Eleostearic Acid Ameliorates Experimental Inflammatory Bowel Disease in Mice by Activating Peroxisome Proliferator-Activated Receptor-?
Wednesday, August 31, 2011
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An Artemisinin-Derived Dimer Has Highly Potent Anti-Cytomegalovirus (CMV) and Anti-Cancer Activities
Wednesday, August 31, 2011
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Stressing the Ubiquitin-Proteasome System without 20S Proteolytic Inhibition Selectively Kills Cervical Cancer Cells
Wednesday, August 31, 2011
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The K+ Channel Opener 1-EBIO Potentiates Residual Function of Mutant CFTR in Rectal Biopsies from Cystic Fibrosis Patients
Wednesday, August 31, 2011
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Characterization of the Psychological, Physiological and EEG Profile of Acute Betel Quid Intoxication in Naïve Subjects
Wednesday, August 31, 2011
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Serum Penicillin G Levels Are Lower Than Expected in Adults within Two Weeks of Administration of 1.2 Million Units
Tuesday, October 04, 2011
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Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity
Wednesday, October 05, 2011
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Xanthene Food Dye, as a Modulator of Alzheimer's Disease Amyloid-beta Peptide Aggregation and the Associated Impaired Neuronal Cell Function
Wednesday, October 05, 2011
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New Insight into the Molecular Mechanisms of the Biological Effects of DNA Minor Groove Binders
Wednesday, October 05, 2011
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Direct Translocation as Major Cellular Uptake for CADY Self-Assembling Peptide-Based Nanoparticles
Wednesday, October 05, 2011
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Praziquantel Facilitates IFN-?-Producing CD8+ T Cells (Tc1) and IL-17-Producing CD8+ T Cells (Tc17) Responses to DNA Vaccination in Mice
Wednesday, October 05, 2011
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A Novel Genotype of GB Virus C: Its Identification and Predominance among Injecting Drug Users in Yunnan, China
Thursday, October 06, 2011
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Peroral Amphotericin B Polymer Nanoparticles Lead to Comparable or Superior In Vivo Antifungal Activity to That of Intravenous Ambisome® or Fungizone™
Thursday, October 06, 2011
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Lack of Effect of Methylene Blue in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis
Thursday, October 06, 2011
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15-Deoxy-?12,14 Prostaglandin J2 Reduces the Formation of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice
Friday, October 07, 2011
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Ligand-Directed Functional Selectivity at the Mu Opioid Receptor Revealed by Label-Free Integrative Pharmacology On-Target
Friday, October 07, 2011
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Effect of ABCB1 and ABCC3 Polymorphisms on Osteosarcoma Survival after Chemotherapy: A Pharmacogenetic Study
Friday, October 07, 2011
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Liver Afferents Contribute to Water Drinking-Induced Sympathetic Activation in Human Subjects: A Clinical Trial
Friday, October 07, 2011
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The Role of Early Life Experience and Species Differences in Alcohol Intake in Microtine Rodents
Friday, June 22, 2012
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Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study
Friday, June 22, 2012
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Role of IKK/NF-?B Signaling in Extinction of Conditioned Place Aversion Memory in Rats
Tuesday, June 26, 2012
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A Phthalimide Derivative That Inhibits Centrosomal Clustering Is Effective on Multiple Myeloma
Monday, June 25, 2012
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Human Peripheral Blood Mononuclear Cells Exhibit Heterogeneous CD52 Expression Levels and Show Differential Sensitivity to Alemtuzumab Mediated Cytolysis
Monday, June 25, 2012
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Inhibition of Hippocampal Synaptic Activity by ATP, Hypoxia or Oxygen-Glucose Deprivation Does Not Require CD73
Monday, June 25, 2012
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Thaliporphine Preserves Cardiac Function of Endotoxemic Rabbits by Both Directly and Indirectly Attenuating NF?B Signaling Pathway
Monday, June 25, 2012
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Neutralization of IL-8 Prevents the Induction of Dermatologic Adverse Events Associated with the Inhibition of Epidermal Growth Factor Receptor
Monday, June 25, 2012
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Programmed Chemotherapy for Patients with Metastatic Unresectable Gastric Cancer
Tuesday, June 26, 2012
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UniDrug-Target: A Computational Tool to Identify Unique Drug Targets in Pathogenic Bacteria
Wednesday, March 14, 2012
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Identification of Common Biological Pathways and Drug Targets Across Multiple Respiratory Viruses Based on Human Host Gene Expression Analysis
Wednesday, March 14, 2012
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SAHA Decreases HDAC 2 and 4 Levels In Vivo and Improves Molecular Phenotypes in the R6/2 Mouse Model of Huntington's Disease
Monday, November 28, 2011
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Darinaparsin Is a Multivalent Chemotherapeutic Which Induces Incomplete Stress Response with Disruption of Microtubules and Shh Signaling
Tuesday, November 15, 2011
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Astragalus Polysaccharides Lowers Plasma Cholesterol through Mechanisms Distinct from Statins
Wednesday, November 16, 2011
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Potential Biomarkers in Mouse Myocardium of Doxorubicin-Induced Cardiomyopathy: A Metabonomic Method and Its Application
Wednesday, November 16, 2011
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Design, Synthesis, and Pharmacological Evaluation of Haloperidol Derivatives as Novel Potent Calcium Channel Blockers with Vasodilator Activity
Wednesday, November 16, 2011
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FDA-Approved Drugs that Protect Mammalian Neurons from Glucose Toxicity Slow Aging Dependent on Cbp and Protect Against Proteotoxicity
Wednesday, November 16, 2011
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Adolescent Oxytocin Exposure Causes Persistent Reductions in Anxiety and Alcohol Consumption and Enhances Sociability in Rats
Wednesday, November 16, 2011
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Clinical and Genetic Determinants of Warfarin Pharmacokinetics and Pharmacodynamics during Treatment Initiation
Wednesday, November 16, 2011
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Antibiotics Shaping Bacterial Genome: Deletion of an IS91 Flanked Virulence Determinant upon Exposure to Subinhibitory Antibiotic Concentrations
Friday, November 11, 2011
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A TNF Receptor 2 Selective Agonist Rescues Human Neurons from Oxidative Stress-Induced Cell Death
Monday, November 14, 2011
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The HIV-1 Vpu Viroporin Inhibitor BIT225 Does Not Affect Vpu-Mediated Tetherin Antagonism
Monday, November 14, 2011
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Methamphetamine Increases LPS-Mediated Expression of IL-8, TNF-a and IL-1ß in Human Macrophages through Common Signaling Pathways
Thursday, March 29, 2012
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Nicorandil Attenuates Monocrotaline-Induced Vascular Endothelial Damage and Pulmonary Arterial Hypertension
Friday, March 30, 2012
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Prion Protein Is a Key Determinant of Alcohol Sensitivity through the Modulation of N-Methyl-D-Aspartate Receptor (NMDAR) Activity
Friday, April 20, 2012
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Enhancing the Antibiotic Antibacterial Effect by Sub Lethal Tellurite Concentrations: Tellurite and Cefotaxime Act Synergistically in Escherichia coli
Friday, April 20, 2012
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Anti-HIV-1 Activity of a New Scorpion Venom Peptide Derivative Kn2-7
Thursday, April 19, 2012
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Enhanced Brain Disposition and Effects of ?9-Tetrahydrocannabinol in P-Glycoprotein and Breast Cancer Resistance Protein Knockout Mice
Friday, April 20, 2012
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DW-MRI as a Biomarker to Compare Therapeutic Outcomes in Radiotherapy Regimens Incorporating Temozolomide or Gemcitabine in Glioblastoma
Friday, April 20, 2012
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Lestaurtinib Inhibits Histone Phosphorylation and Androgen-Dependent Gene Expression in Prostate Cancer Cells
Friday, April 20, 2012
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The Effect of Rosuvastatin in a Murine Model of Influenza A Infection
Friday, April 20, 2012
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Influence of Various Polymorphic Variants of Cytochrome P450 Oxidoreductase (POR) on Drug Metabolic Activity of CYP3A4 and CYP2B6
Tuesday, June 12, 2012
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The HCV Non-Nucleoside Inhibitor Tegobuvir Utilizes a Novel Mechanism of Action to Inhibit NS5B Polymerase Function
Wednesday, June 13, 2012
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Results and Outcome Reporting In ClinicalTrials.gov, What Makes it Happen?
Wednesday, June 13, 2012
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Implementation and Conduct of Therapeutic Hypothermia for Perinatal Asphyxial Encephalopathy in the UK – Analysis of National Data
Wednesday, June 13, 2012
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HbA1c Measured in Stored Erythrocytes Is Positively Linearly Associated with Mortality in Individuals with Diabetes Mellitus
Wednesday, June 13, 2012
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Humanized Mice Recapitulate Key Features of HIV-1 Infection: A Novel Concept Using Long-Acting Anti-Retroviral Drugs for Treating HIV-1
Wednesday, June 13, 2012
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Changes in Bone Turnover and Bone Loss in HIV-Infected Patients Changing Treatment to Tenofovir-Emtricitabine or Abacavir-Lamivudine
Friday, June 15, 2012
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Low Serum Glutathione Peroxidase Activity Is Associated with Increased Cardiovascular Mortality in Individuals with Low HDLc’s
Friday, June 15, 2012
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A Two-Step Target Binding and Selectivity Support Vector Machines Approach for Virtual Screening of Dopamine Receptor Subtype-Selective Ligands
Friday, June 15, 2012
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Small Molecules with Similar Structures Exhibit Agonist, Neutral Antagonist or Inverse Agonist Activity toward Angiotensin II Type 1 Receptor
Thursday, June 14, 2012
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Ubiquitin-Specific Peptidase 46 (Usp46) Regulates Mouse Immobile Behavior in the Tail Suspension Test through the GABAergic System
Thursday, June 14, 2012
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Inhibition of Soluble Epoxide Hydrolase Attenuates High-Fat-Diet–Induced Hepatic Steatosis by Reduced Systemic Inflammatory Status in Mice
Thursday, June 14, 2012
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Combined Cocaine Hydrolase Gene Transfer and Anti-Cocaine Vaccine Synergistically Block Cocaine-Induced Locomotion
Friday, August 17, 2012
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Impacts of Brain Serotonin Deficiency following Tph2 Inactivation on Development and Raphe Neuron Serotonergic Specification
Friday, August 17, 2012
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Prediction of the Pharmacokinetic Parameters of Triptolide in Rats Based on Endogenous Molecules in Pre-Dose Baseline Serum
Friday, August 17, 2012
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A Longitudinal Trial Comparing Chloroquine as Monotherapy or in Combination with Artesunate, Azithromycin or Atovaquone-Proguanil to Treat Malaria
Friday, August 17, 2012
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Mitochondrial Respiration - An Important Therapeutic Target in Melanoma
Friday, August 17, 2012
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Glass Shape Influences Consumption Rate for Alcoholic Beverages
Friday, August 17, 2012
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Autotaxin-Lysophosphatidic Acid Axis Is a Novel Molecular Target for Lowering Intraocular Pressure
Monday, August 20, 2012
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An Efficient Computational Method for Calculating Ligand Binding Affinities
Monday, August 20, 2012
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Design and Synthesis of Potent N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitor as Anti-Inflammatory Compounds
Monday, August 20, 2012
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ING1 and 5-Azacytidine Act Synergistically to Block Breast Cancer Cell Growth
Monday, August 20, 2012
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Overexpression of ORCA3 and G10H in Catharanthus roseus Plants Regulated Alkaloid Biosynthesis and Metabolism Revealed by NMR-Metabolomics
Monday, August 20, 2012
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Prevention of Ocular Scarring Post Glaucoma Filtration Surgery Using the Inflammatory Cell and Platelet Binding Modulator Saratin in a Rabbit Model
Monday, April 30, 2012
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Implications of Altered Glutathione Metabolism in Aspirin-Induced Oxidative Stress and Mitochondrial Dysfunction in HepG2 Cells
Monday, April 30, 2012
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The Influence of Spin-Labeled Fluorene Compounds on the Assembly and Toxicity of the Aß Peptide
Monday, April 30, 2012
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Features of Idebenone and Related Short-Chain Quinones that Rescue ATP Levels under Conditions of Impaired Mitochondrial Complex I
Friday, April 27, 2012
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The Antibody Targeting the E314 Peptide of Human Kv1.3 Pore Region Serves as a Novel, Potent and Specific Channel Blocker
Friday, April 27, 2012
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Aliskiren Prevents the Toxic Effects of Peritoneal Dialysis Fluids during Chronic Dialysis in Rats
Friday, April 27, 2012
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Recombinant GPI-Anchored TIMP-1 Stimulates Growth and Migration of Peritoneal Mesothelial Cells
Friday, April 27, 2012
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Importance of Intracellular pH in Determining the Uptake and Efficacy of the Weakly Basic Chemotherapeutic Drug, Doxorubicin
Thursday, April 26, 2012
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Molecular Dynamics Simulation of the Complex PBP-2x with Drug Cefuroxime to Explore the Drug Resistance Mechanism of Streptococcus suis R61
Thursday, April 26, 2012
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IspE Inhibitors Identified by a Combination of In Silico and In Vitro High-Throughput Screening
Wednesday, April 25, 2012
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Different Effects of Farrerol on an OVA-Induced Allergic Asthma and LPS-induced Acute Lung Injury
Thursday, April 26, 2012
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Targeted Delivery of Chemotherapy Agents Using a Liver Cancer-Specific Aptamer
Wednesday, April 25, 2012
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Impact of Natalizumab on Cognitive Performances and Fatigue in Relapsing Multiple Sclerosis: A Prospective, Open-Label, Two Years Observational Study
Wednesday, April 25, 2012
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Protection of Rat Cardiac Myocytes by Fructose-1,6-Bisphosphate and 2,3-Butanedione
Friday, April 27, 2012
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Expression of ABC Efflux Transporters in Placenta from Women with Insulin-Managed Diabetes
Friday, April 27, 2012
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Suramin Alleviates Glomerular Injury and Inflammation in the Remnant Kidney
Friday, April 27, 2012
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KIOM-79 Protects AGE-Induced Retinal Pericyte Apoptosis via Inhibition of NF-kappaB Activation In Vitro and In Vivo
Monday, August 20, 2012
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Pre-Clinical Development of BCG.HIVACAT, an Antibiotic-Free Selection Strain, for HIV-TB Pediatric Vaccine Vectored by Lysine Auxotroph of BCG
Tuesday, August 21, 2012
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Probing the Binding Sites of Antibiotic Drugs Doxorubicin and N-(trifluoroacetyl) Doxorubicin with Human and Bovine Serum Albumins
Friday, August 24, 2012
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Screen Anti-influenza Lead Compounds That Target the PAC Subunit of H5N1 Viral RNA Polymerase
Friday, August 24, 2012
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Integration in Working Memory: A Magnetic Stimulation Study on the Role of Left Anterior Prefrontal Cortex
Friday, August 24, 2012
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Clitocine Reversal of P-Glycoprotein Associated Multi-Drug Resistance through Down-Regulation of Transcription Factor NF-?B in R-HepG2 Cell Line
Wednesday, August 22, 2012
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A Survey of the FDA's AERS Database Regarding Muscle and Tendon Adverse Events Linked to the Statin Drug Class
Wednesday, August 22, 2012
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Inappropriateness of Medication Prescriptions to Elderly Patients in the Primary Care Setting: A Systematic Review
Wednesday, August 22, 2012
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The Role of Dorsal Anterior Cingulate Cortex in the Regulation of Craving by Reappraisal in Smokers
Wednesday, August 22, 2012
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Efficacy of Oral Metronidazole with Vaginal Clindamycin or Vaginal Probiotic for Bacterial Vaginosis: Randomised Placebo-Controlled Double-Blind Trial
Tuesday, April 03, 2012
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The Frequency of Malaria Is Similar among Women Receiving either Lopinavir/Ritonavir or Nevirapine-based Antiretroviral Treatment
Tuesday, April 03, 2012
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Thrombospondin-1 Type 1 Repeats in a Model of Inflammatory Bowel Disease: Transcript Profile and Therapeutic Effects
Tuesday, April 03, 2012
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A Prompt to the Web: The Media and Health Information Seeking Behaviour
Tuesday, April 03, 2012
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The 5HT1a Receptor Agonist 8-Oh DPAT Induces Protection from Lipofuscin Accumulation and Oxidative Stress in the Retinal Pigment Epithelium
Tuesday, April 03, 2012
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Assessment of Chitosan-Affected Metabolic Response by Peroxisome Proliferator-Activated Receptor Bioluminescent Imaging-Guided Transcriptomic Analysis
Wednesday, April 04, 2012
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Differential Inflammatory Response to Inhaled Lipopolysaccharide Targeted Either to the Airways or the Alveoli in Man
Wednesday, April 04, 2012
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Off-Label Biologic Regimens in Psoriasis: A Systematic Review of Efficacy and Safety of Dose Escalation, Reduction, and Interrupted Biologic Therapy
Wednesday, April 11, 2012
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Infant Safety during and after Maternal Valacyclovir Therapy in Conjunction with Antiretroviral HIV-1 Prophylaxis in a Randomized Clinical Trial
Wednesday, April 11, 2012
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Effect on Adherence to Nicotine Replacement Therapy of Informing Smokers Their Dose Is Determined by Their Genotype: A Randomised Controlled Trial
Wednesday, April 11, 2012
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Distinct Effects of Unfractionated Heparin versus Bivalirudin on Circulating Angiogenic Peptides
Wednesday, April 11, 2012
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Early Treatment with Fumagillin, an Inhibitor of Methionine Aminopeptidase-2, Prevents Pulmonary Hypertension in Monocrotaline-Injured Rats
Wednesday, April 11, 2012
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Efficacy of Short-Term High-Dose Statin in Preventing Contrast-Induced Nephropathy: A Meta-Analysis of Seven Randomized Controlled Trials
Thursday, April 12, 2012
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Delayed Toxicity Associated with Soluble Anthrax Toxin Receptor Decoy-Ig Fusion Protein Treatment
Thursday, April 12, 2012
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Genetic Dissection of Acute Ethanol Responsive Gene Networks in Prefrontal Cortex: Functional and Mechanistic Implications
Thursday, April 12, 2012
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Predicting Anatomical Therapeutic Chemical (ATC) Classification of Drugs by Integrating Chemical-Chemical Interactions and Similarities
Friday, April 13, 2012
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Collaborative Enhancement of Antibody Binding to Distinct PECAM-1 Epitopes Modulates Endothelial Targeting
Friday, April 13, 2012
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Activity of Clinically Relevant Antimalarial Drugs on Plasmodium falciparum Mature Gametocytes in an ATP Bioluminescence “Transmission Blocking” Assay
Friday, April 13, 2012
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Angiopreventive Efficacy of Pure Flavonolignans from Milk Thistle Extract against Prostate Cancer: Targeting VEGF-VEGFR Signaling
Friday, April 13, 2012
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Polysaccharides from Wolfberry Prevents Corticosterone-Induced Inhibition of Sexual Behavior and Increases Neurogenesis
Monday, April 16, 2012
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Cardiovascular Events in Patients Received Combined Fibrate/Statin Treatment versus Statin Monotherapy: Acute Coronary Syndrome Israeli Surveys Data
Monday, April 16, 2012
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Regulation of Chemokine and Chemokine Receptor Expression by PPAR? in Adipocytes and Macrophages
Tuesday, April 17, 2012
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Pilot Scale Production of Highly Efficacious and Stable Enterovirus 71 Vaccine Candidates
Tuesday, April 17, 2012
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Designing and Analyzing Clinical Trials with Composite Outcomes: Consideration of Possible Treatment Differences between the Individual Outcomes
Tuesday, April 17, 2012
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Stereoselective Regulations of P-Glycoprotein by Ginsenoside Rh2 Epimers and the Potential Mechanisms From the View of Pharmacokinetics
Wednesday, April 18, 2012
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Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy
Wednesday, April 18, 2012
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Biodegradable Thermosensitive Hydrogel for SAHA and DDP Delivery: Therapeutic Effects on Oral Squamous Cell Carcinoma Xenografts
Wednesday, April 18, 2012
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Human Occupancy as a Source of Indoor Airborne Bacteria
Wednesday, April 18, 2012
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Propylthiouracil Is Teratogenic in Murine Embryos
Wednesday, April 18, 2012
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GRP78 Knockdown Enhances Apoptosis via the Down-Regulation of Oxidative Stress and Akt Pathway after Epirubicin Treatment in Colon Cancer DLD-1 Cells
Wednesday, April 18, 2012
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Role of Serine Racemase in Behavioral Sensitization in Mice after Repeated Administration of Methamphetamine
Wednesday, April 18, 2012
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Male-Dominant Activation of Rat Renal Organic Anion Transporter 1 (Oat1) and 3 (Oat3) Expression by Transcription Factor BCL6
Wednesday, April 18, 2012
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JKA97, a Novel Benzylidene Analog of Harmine, Exerts Anti-Cancer Effects by Inducing G1 Arrest, Apoptosis, and p53-Independent Up-Regulation of p21
Friday, April 27, 2012
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Securin Enhances the Anti-Cancer Effects of 6-Methoxy-3-(3',4',5'-Trimethoxy-Benzoyl)-1H-Indole (BPR0L075) in Human Colorectal Cancer Cells
Thursday, April 26, 2012
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Effects of PPARs Agonists on Cardiac Metabolism in Littermate and Cardiomyocyte-Specific PPAR-? –Knockout (CM-PGKO) Mice
Thursday, April 26, 2012
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The Carbon Monoxide Releasing Molecule CORM-2 Attenuates Pseudomonas aeruginosa Biofilm Formation
Thursday, April 26, 2012
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Differential Scanning Fluorometry Signatures as Indicators of Enzyme Inhibitor Mode of Action: Case Study of Glutathione S-Transferase
Monday, April 30, 2012
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Dysfunction in Fatty Acid Amide Hydrolase Is Associated with Depressive-Like Behavior in Wistar Kyoto Rats
Monday, May 14, 2012
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Skin-Targeted Inhibition of PPAR ß/d by Selective Antagonists to Treat PPAR ß/d – Mediated Psoriasis-Like Skin Disease In Vivo
Monday, May 14, 2012
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The Tyrphostin Agent AG490 Prevents and Reverses Type 1 Diabetes in NOD Mice
Monday, May 14, 2012
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Inhibition Mechanism and Model of an Angiotensin I-Converting Enzyme (ACE)-Inhibitory Hexapeptide from Yeast (Saccharomyces cerevisiae)
Monday, May 14, 2012
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Reward-Related Dorsal Striatal Activity Differences between Former and Current Cocaine Dependent Individuals during an Interactive Competitive Game
Monday, May 14, 2012
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Profiles of Multidrug Resistance Protein-1 in the Peripheral Blood Mononuclear Cells of Patients with Refractory Epilepsy
Monday, May 14, 2012
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Small-Molecule Synthetic Compound Norcantharidin Reverses Multi-Drug Resistance by Regulating Sonic Hedgehog Signaling in Human Breast Cancer Cells
Tuesday, May 15, 2012
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Herbal Medicines for Parkinson's Disease: A Systematic Review of Randomized Controlled Trials
Tuesday, May 15, 2012
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Riboflavin Ameliorates Cisplatin Induced Toxicities under Photoillumination
Wednesday, May 02, 2012
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Young HIV-Infected Children and Their Adult Caregivers Prefer Tablets to Syrup Antiretroviral Medications in Africa
Wednesday, May 02, 2012
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The Interaction between Early Life Epilepsy and Autistic-Like Behavioral Consequences: A Role for the Mammalian Target of Rapamycin (mTOR) Pathway
Wednesday, May 02, 2012
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Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia
Thursday, May 03, 2012
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Inhibition of EP4 Signaling Attenuates Aortic Aneurysm Formation
Thursday, May 03, 2012
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Heart Rate and Use of Beta-Blockers in Stable Outpatients with Coronary Artery Disease
Thursday, May 03, 2012
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Meta-Analysis on the Effects of Octreotide on Tumor Mass in Acromegaly
Friday, May 04, 2012
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A Novel Solid-Phase Site-Specific PEGylation Enhances the In Vitro and In Vivo Biostabilty of Recombinant Human Keratinocyte Growth Factor 1
Friday, May 04, 2012
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High Throughput Screening for Small Molecule Enhanc |