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Pharmacology
 
Exposure to Non-Steroidal Anti-Inflammatory Drugs during Pregnancy and the Risk of Selected Birth Defects: A Prospective Cohort Study  Monday, July 18, 2011   More...
Proteomic Biomarkers for Acute Interstitial Lung Disease in Gefitinib-Treated Japanese Lung Cancer Patients  Wednesday, July 20, 2011   More...
A New Method to Address Unmet Needs for Extracting Individual Cell Migration Features from a Large Number of Cells Embedded in 3D Volumes  Friday, July 15, 2011   More...
Network Neighbors of Drug Targets Contribute to Drug Side-Effect Similarity  Wednesday, July 13, 2011   More...
Anatomical Differences Determine Distribution of Adenovirus after Convection-Enhanced Delivery to the Rat Brain  Thursday, October 13, 2011   More...
A Human TREK-1/HEK Cell Line: A Highly Efficient Screening Tool for Drug Development in Neurological Diseases  Friday, October 14, 2011   More...
Hydrogen Sulfide Attenuates Carbon Tetrachloride-Induced Hepatotoxicity, Liver Cirrhosis and Portal Hypertension in Rats  Friday, October 14, 2011   More...
Chronic Morphine Alters the Presynaptic Protein Profile: Identification of Novel Molecular Targets Using Proteomics and Network Analysis  Monday, October 17, 2011   More...
Yeast Based Small Molecule Screen for Inhibitors of SARS-CoV  Friday, December 02, 2011   More...
The Tyrosine Kinase Inhibitor Dasatinib Induces a Marked Adipogenic Differentiation of Human Multipotent Mesenchymal Stromal Cells  Friday, December 02, 2011   More...
Chinese Herbal Medicines for the Treatment of Type A H1N1 Influenza: A Systematic Review of Randomized Controlled Trials  Friday, December 02, 2011   More...
Publication Delay of Randomized Trials on 2009 Influenza A (H1N1) Vaccination  Friday, December 02, 2011   More...
The Redistribution of Power: Neurocardiac Signaling, Alcohol and Gender  Friday, December 02, 2011   More...
Inhibition of G Protein-Activated Inwardly Rectifying K+ Channels by Different Classes of Antidepressants  Friday, December 02, 2011   More...
Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis  Tuesday, December 06, 2011   More...
Oseltamivir Prescription and Regulatory Actions Vis-à-Vis Abnormal Behavior Risk in Japan: Drug Utilization Study Using a Nationwide Pharmacy Database  Tuesday, December 06, 2011   More...
Pharmacogenetic & Pharmacokinetic Biomarker for Efavirenz Based ARV and Rifampicin Based Anti-TB Drug Induced Liver Injury in TB-HIV Infected Patients  Tuesday, December 06, 2011   More...
Incidence of Epileptiform EEG Activity in Children during Mask Induction of Anaesthesia with Brief Administration of 8% Sevoflurane  Thursday, July 19, 2012   More...
Transferrin Coated Nanoparticles: Study of the Bionano Interface in Human Plasma  Thursday, July 19, 2012   More...
Physalin F Induces Cell Apoptosis in Human Renal Carcinoma Cells by Targeting NF-kappaB and Generating Reactive Oxygen Species  Monday, July 16, 2012   More...
Insertion of Short Amino-Functionalized Single-Walled Carbon Nanotubes into Phospholipid Bilayer Occurs by Passive Diffusion  Monday, July 16, 2012   More...
Exploration of the Association Rules Mining Technique for the Signal Detection of Adverse Drug Events in Spontaneous Reporting Systems  Monday, July 16, 2012   More...
N-Acetylcysteine Protects Rats with Chronic Renal Failure from Gadolinium-Chelate Nephrotoxicity  Monday, July 16, 2012   More...
Alleviation of Gut Inflammation by Cdx2/Pxr Pathway in a Mouse Model of Chemical Colitis  Monday, July 16, 2012   More...
Intracellular Retention of ABL Kinase Inhibitors Determines Commitment to Apoptosis in CML Cells  Monday, July 16, 2012   More...
Roflumilast-N-oxide Induces Surfactant Protein Expression in Human Alveolar Epithelial Cells Type II  Monday, July 16, 2012   More...
The Aryl Hydrocarbon Receptor Mediates Leflunomide-Induced Growth Inhibition of Melanoma Cells  Tuesday, July 17, 2012   More...
Transfer of Neuroplasticity from Nucleus Accumbens Core to Shell Is Required for Cocaine Reward  Tuesday, January 17, 2012   More...
Modelling of Mouse Experimental Colitis by Global Property Screens: A Holistic Approach to Assess Drug Effects in Inflammatory Bowel Disease  Wednesday, January 18, 2012   More...
Rapid Evaluation in Whole Blood Culture of Regimens for XDR-TB Containing PNU-100480 (Sutezolid), TMC207, PA-824, SQ109, and Pyrazinamide  Wednesday, January 18, 2012   More...
Synthesis, Biological Evaluation and Mechanism Studies of Deoxytylophorinine and Its Derivatives as Potential Anticancer Agents  Thursday, January 19, 2012   More...
Withdrawal from Cocaine Self-Administration Alters NMDA Receptor-Mediated Ca2+ Entry in Nucleus Accumbens Dendritic Spines  Friday, August 03, 2012   More...
A Safety Review and Meta-Analyses of Bevacizumab and Ranibizumab: Off-Label versus Goldstandard  Friday, August 03, 2012   More...
Markov Models of Use-Dependence and Reverse Use-Dependence during the Mouse Cardiac Action Potential  Monday, August 06, 2012   More...
Understanding the Basis of Drug Resistance of the Mutants of aß-Tubulin Dimer via Molecular Dynamics Simulations  Tuesday, August 07, 2012   More...
A VLP Vaccine Induces Broad-Spectrum Cross-Protective Antibody Immunity against H5N1 and H1N1 Subtypes of Influenza A Virus  Tuesday, August 07, 2012   More...
Osteopontin Reduces Biofilm Formation in a Multi-Species Model of Dental Biofilm  Tuesday, August 07, 2012   More...
Presynaptic Selectivity of a Ligand for Serotonin 1A Receptors Revealed by In Vivo PET Assays of Rat Brain  Tuesday, August 07, 2012   More...
Mephedrone in Adolescent Rats: Residual Memory Impairment and Acute but Not Lasting 5-HT Depletion  Tuesday, September 18, 2012   More...
Adverse Drug Reactions in Hospitalised Children in Germany Are Decreasing: Results of a Nine Year Cohort-Based Comparison  Tuesday, September 18, 2012   More...
Metabolomic Profiling to Identify Predictors of Response to Vitamin E for Non-Alcoholic Steatohepatitis (NASH)  Wednesday, September 19, 2012   More...
Valproic Acid Downregulates RBP4 and Elicits Hypervitaminosis A-Teratogenesis—A Kinetic Analysis on Retinol/Retinoic Acid Homeostatic System  Wednesday, September 19, 2012   More...
Local Delivery of Nimodipine by Prolonged-Release Microparticles—Feasibility, Effectiveness and Dose-Finding in Experimental Subarachnoid Hemorrhage  Tuesday, September 25, 2012   More...
Unexpected Neuronal Protection of SU5416 against 1-Methyl-4-Phenylpyridinium Ion-Induced Toxicity via Inhibiting Neuronal Nitric Oxide Synthase  Tuesday, September 25, 2012   More...
Individual and County-Level Factors Associated with Use of Multiple Prescribers and Multiple Pharmacies to Obtain Opioid Prescriptions in California  Tuesday, September 25, 2012   More...
A Synthetic Chloride Channel Relaxes Airway Smooth Muscle of the Rat  Wednesday, September 26, 2012   More...
Synergism and Rules from Combination of Baicalin, Jasminoidin and Desoxycholic acid in Refined Qing Kai Ling for Treat Ischemic Stroke Mice Model  Wednesday, September 26, 2012   More...
Evaluation of Environmental Contamination and Estimated Radiation Doses for the Return to Residents’ Homes in Kawauchi Village, Fukushima Prefecture  Wednesday, September 26, 2012   More...
Medical Care and Payment for Diabetes in China: Enormous Threat and Great Opportunity  Wednesday, September 26, 2012   More...
Antimalarial Activity of Potential Inhibitors of Plasmodium falciparum Lactate Dehydrogenase Enzyme Selected by Docking Studies  Thursday, July 14, 2011   More...
Galiellalactone Inhibits Stem Cell-Like ALDH-Positive Prostate Cancer Cells  Monday, July 11, 2011   More...
Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma  Wednesday, July 06, 2011   More...
Rescue of Photoreceptor Degeneration by Curcumin in Transgenic Rats with P23H Rhodopsin Mutation  Wednesday, June 29, 2011   More...
Histological Observation of Islet Hemorrhage Induced by Diagnostic Ultrasound with Contrast Agent in Rat Pancreas  Tuesday, June 28, 2011   More...
Escitalopram and Neuroendocrine Response in Healthy First-Degree Relatives to Depressed Patients – A Randomized Placebo-Controlled Trial  Monday, June 27, 2011   More...
Fisetin Lowers Methylglyoxal Dependent Protein Glycation and Limits the Complications of Diabetes  Monday, June 27, 2011   More...
Environmental Enrichment Preceding Early Adulthood Methylphenidate Treatment Leads to Long Term Increase of Corticosterone and Testosterone in the Rat  Friday, July 15, 2011   More...
Chlorpromazine Protects Against Apoptosis Induced by Exogenous Stimuli in the Developing Rat Brain  Thursday, July 14, 2011   More...
Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity  Wednesday, July 06, 2011   More...
Triple Combination Antiviral Drug (TCAD) Composed of Amantadine, Oseltamivir, and Ribavirin Impedes the Selection of Drug-Resistant Influenza A Virus  Thursday, December 29, 2011   More...
Inhibition of Reactive Gliosis Prevents Neovascular Growth in the Mouse Model of Oxygen-Induced Retinopathy  Thursday, July 14, 2011   More...
Orally Active Multi-Functional Antioxidants Are Neuroprotective in a Rat Model of Light-Induced Retinal Damage  Thursday, July 14, 2011   More...
Epidemiological Surveillance of Birth Defects Compatible with Thalidomide Embryopathy in Brazil  Wednesday, July 06, 2011   More...
AST1306, A Novel Irreversible Inhibitor of the Epidermal Growth Factor Receptor 1 and 2, Exhibits Antitumor Activity Both In Vitro and In Vivo  Monday, July 18, 2011   More...
Soluble Guanylate Cyclase Stimulation Prevents Fibrotic Tissue Remodeling and Improves Survival in Salt-Sensitive Dahl Rats  Monday, July 18, 2011   More...
Proton Pump Inhibitors Inhibit Metformin Uptake by Organic Cation Transporters (OCTs)  Thursday, July 14, 2011   More...
Intra-Accumbens Injection of a Dopamine Aptamer Abates MK-801-Induced Cognitive Dysfunction in a Model of Schizophrenia  Wednesday, July 13, 2011   More...
Reappearance of Minority K103N HIV-1 Variants after Interruption of ART Initiated during Primary HIV-1 Infection  Wednesday, July 06, 2011   More...
Genome-Wide Local Ancestry Approach Identifies Genes and Variants Associated with Chemotherapeutic Susceptibility in African Americans  Wednesday, July 06, 2011   More...
Donepezil, Anti-Alzheimer's Disease Drug, Prevents Cardiac Rupture during Acute Phase of Myocardial Infarction in Mice  Tuesday, July 05, 2011   More...
2-Deoxy-D-Glucose Treatment Induces Ketogenesis, Sustains Mitochondrial Function, and Reduces Pathology in Female Mouse Model of Alzheimer's Disease  Friday, July 01, 2011   More...
Iminosugar-Based Inhibitors of Glucosylceramide Synthase Increase Brain Glycosphingolipids and Survival in a Mouse Model of Sandhoff Disease  Wednesday, June 29, 2011   More...
Specific ß-Tubulin Isotypes Can Functionally Enhance or Diminish Epothilone B Sensitivity in Non-Small Cell Lung Cancer Cells  Wednesday, June 29, 2011   More...
Randomized Trial of Time-Limited Interruptions of Protease Inhibitor-Based Antiretroviral Therapy (ART) vs. Continuous Therapy for HIV-1 Infection  Tuesday, June 28, 2011   More...
Inhibitory Role of Inducible cAMP Early Repressor (ICER) in Methamphetamine-Induced Locomotor Sensitization  Tuesday, June 28, 2011   More...
H2S Donor, S-Propargyl-Cysteine, Increases CSE in SGC-7901 and Cancer-Induced Mice: Evidence for a Novel Anti-Cancer Effect of Endogenous H2S?  Monday, June 27, 2011   More...
High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria  Monday, July 25, 2011   More...
Frequent Use of Paracetamol and Risk of Allergic Disease Among Women in an Ethiopian Population  Thursday, July 21, 2011   More...
An Integrative View of Mechanisms Underlying Generalized Spike-and-Wave Epileptic Seizures and Its Implication on Optimal Therapeutic Treatments  Thursday, July 21, 2011   More...
A Prokaryotic S1P Lyase Degrades Extracellular S1P In Vitro and In Vivo: Implication for Treating Hyperproliferative Disorders  Monday, August 01, 2011   More...
Sensitive and Specific Fluorescent Probes for Functional Analysis of the Three Major Types of Mammalian ABC Transporters  Friday, July 22, 2011   More...
Losartan Slows Pancreatic Tumor Progression and Extends Survival of SPARC-Null Mice by Abrogating Aberrant TGFß Activation  Tuesday, February 14, 2012   More...
The Transcriptional Response of Caenorhabditis elegans to Ivermectin Exposure Identifies Novel Genes Involved in the Response to Reduced Food Intake  Tuesday, February 14, 2012   More...
Extra-Renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG2  Friday, February 10, 2012   More...
Activation of PKCzeta and PKMzeta in the Nucleus Accumbens Core Is Necessary for the Retrieval, Consolidation and Reconsolidation of Drug Memory  Friday, February 10, 2012   More...
Efficacy of Different Nitric Oxide-Based Strategies in Preventing Experimental Cerebral Malaria by Plasmodium berghei ANKA  Monday, February 13, 2012   More...
Quercetin-4'-O-ß-D-glucopyranoside (QODG) Inhibits Angiogenesis by Suppressing VEGFR2-Mediated Signaling in Zebrafish and Endothelial Cells  Monday, February 13, 2012   More...
Short- and Long-Term Cognitive Effects of Chronic Cannabinoids Administration in Late-Adolescence Rats  Monday, February 13, 2012   More...
Virtual Screening, Identification and In Vitro Testing of Novel Inhibitors of O-Acetyl-L-Serine Sulfhydrylase of Entamoeba histolytica  Wednesday, February 15, 2012   More...
Involvement of Noradrenergic Transmission in the PVN on CREB Activation, TORC1 Levels, and Pituitary-Adrenal Axis Activity during Morphine Withdrawal  Wednesday, February 15, 2012   More...
Necdin, a p53-Target Gene, Is an Inhibitor of p53-Mediated Growth Arrest  Wednesday, February 15, 2012   More...
Multi-Level Targeting of the Phosphatidylinositol-3-Kinase Pathway in Non-Small Cell Lung Cancer Cells  Wednesday, February 15, 2012   More...
Plasma Proteomic Profiling in HIV-1 Infected Methamphetamine Abusers  Thursday, February 16, 2012   More...
Targeting Lysophosphatidic Acid Signaling Retards Culture-Associated Senescence of Human Marrow Stromal Cells  Thursday, February 16, 2012   More...
A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity  Thursday, February 16, 2012   More...
Antifibrinolytic Role of a Bee Venom Serine Protease Inhibitor That Acts as a Plasmin Inhibitor  Thursday, February 16, 2012   More...
Metformin Reduces Hepatic Expression of SIRT3, the Mitochondrial Deacetylase Controlling Energy Metabolism  Friday, November 16, 2012   More...
Case-Only Designs in Pharmacoepidemiology: A Systematic Review  Friday, November 16, 2012   More...
A Metal-Based Inhibitor of NEDD8-Activating Enzyme  Monday, November 19, 2012   More...
A Novel Bioassay for the Activity Determination of Therapeutic Human Brain Natriuretic Peptide (BNP)  Monday, November 19, 2012   More...
Intravenous Amantadine for Freezing of Gait Resistant to Dopaminergic Therapy: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Clinical Trial  Monday, November 19, 2012   More...
DNA Abasic Site-Selective Enhancement of Sanguinarine Fluorescence with a Large Emission Shift  Tuesday, November 20, 2012   More...
Antifibrotic Effects of Roscovitine in Normal and Scleroderma Fibroblasts  Tuesday, November 20, 2012   More...
Levodopa Effects on Hand and Speech Movements in Patients with Parkinson’s Disease: A fMRI Study  Tuesday, October 09, 2012   More...
ABCB1 C3435T Polymorphism and Response to Clopidogrel Treatment in Coronary Artery Disease (CAD) Patients: A Meta-Analysis  Tuesday, October 09, 2012   More...
Adverse Events of Pirfenidone for the Treatment of Pulmonary Fibrosis: A Meta-Analysis of Randomized Controlled Trials  Tuesday, October 09, 2012   More...
Role of Corticotropin-Releasing Factor (CRF) Receptor-1 on the Catecholaminergic Response to Morphine Withdrawal in the Nucleus Accumbens (NAc)  Wednesday, October 10, 2012   More...
A Purpose-Synthesised Anti-Fibrotic Agent Attenuates Experimental Kidney Diseases in the Rat  Wednesday, October 10, 2012   More...
Attenuation of Renovascular Damage in Zucker Diabetic Fatty Rat by NWT-03, an Egg Protein Hydrolysate with ACE- and DPP4-Inhibitory Activity  Wednesday, October 10, 2012   More...
Low-Dose Oral Sirolimus and the Risk of Menstrual-Cycle Disturbances and Ovarian Cysts: Analysis of the Randomized Controlled SUISSE ADPKD Trial  Wednesday, October 10, 2012   More...
Improved Inhibitor Screening Experiments by Comparative Analysis of Simulated Enzyme Progress Curves  Wednesday, October 10, 2012   More...
Oroxylin-A Rescues LPS-Induced Acute Lung Injury via Regulation of NF-?B Signaling Pathway in Rodents  Wednesday, October 10, 2012   More...
Synergistic Antitumor Effects of Endostar in Combination with Oxaliplatin via Inhibition of HIF and CXCR4 in the Colorectal Cell Line SW1116  Wednesday, October 10, 2012   More...
Potential Drug-Drug Interactions in Prescriptions to Patients over 45 Years of Age in Primary Care, Southern Brazil  Wednesday, October 10, 2012   More...
Enhancing Communication about Paediatric Medicines: Lessons from a Qualitative Study of Parents' Experiences of Their Child's Suspected Adverse Drug Reaction  Wednesday, October 10, 2012   More...
Combinatorial Pharmacogenetic Interactions of Bucindolol and ß1, a2C Adrenergic Receptor Polymorphisms  Wednesday, October 10, 2012   More...
Violacein Induces Death of Resistant Leukaemia Cells via Kinome Reprogramming, Endoplasmic Reticulum Stress and Golgi Apparatus Collapse  Thursday, October 11, 2012   More...
Small-Molecule Quinolinol Inhibitor Identified Provides Protection against BoNT/A in Mice  Thursday, October 11, 2012   More...
Macrophages Sequester Clofazimine in an Intracellular Liquid Crystal-Like Supramolecular Organization  Thursday, October 11, 2012   More...
Puerarin Suppresses Proliferation of Endometriotic Stromal Cells Partly via the MAPK Signaling Pathway Induced by 17ß-estradiol-BSA  Wednesday, September 19, 2012   More...
Salinomycin Induces Autophagy in Colon and Breast Cancer Cells with Concomitant Generation of Reactive Oxygen Species  Wednesday, September 19, 2012   More...
Prevention of Disuse Muscle Atrophy by Dietary Ingestion of 8-Prenylnaringenin in Denervated Mice  Wednesday, September 19, 2012   More...
Identification of Early Biomarkers during Acetaminophen-Induced Hepatotoxicity by Fourier Transform Infrared Microspectroscopy  Wednesday, September 19, 2012   More...
Use of Fibrates and Cancer Risk: A Systematic Review and Meta-Analysis of 17 Long-Term Randomized Placebo-Controlled Trials  Wednesday, September 19, 2012   More...
A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity  Wednesday, September 19, 2012   More...
Effects of Paclitaxel on EGFR Endocytic Trafficking Revealed Using Quantum Dot Tracking in Single Cells  Thursday, September 20, 2012   More...
High-Throughput 1,536-Well Fluorescence Polarization Assays for a1-Acid Glycoprotein and Human Serum Albumin Binding  Thursday, September 20, 2012   More...
Activation Biosensor for G Protein-Coupled Receptors: A FRET-Based m1 Muscarinic Activation Sensor That Regulates Gq  Thursday, September 20, 2012   More...
Reverting Antibiotic Tolerance of Pseudomonas aeruginosa PAO1 Persister Cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one  Thursday, September 20, 2012   More...
Eicosapentaenoic Acid and Oxypurinol in the Treatment of Muscle Wasting in a Mouse Model of Cancer Cachexia  Thursday, September 20, 2012   More...
Worsening Endothelial Function with Efavirenz Compared to Protease Inhibitors: A 12-Month Prospective Study  Thursday, September 20, 2012   More...
A Pilot Study to Examine the Effect of Chronic Treatment with Immunosuppressive Drugs on Mucociliary Clearance in a Vagotomized Murine Model  Thursday, September 20, 2012   More...
A 10-Year Analysis of the Effects of Media Coverage of Regulatory Warnings on Antidepressant Use in The Netherlands and UK  Thursday, September 20, 2012   More...
Impairment of Retrograde Neuronal Transport in Oxaliplatin-Induced Neuropathy Demonstrated by Molecular Imaging  Thursday, September 20, 2012   More...
The Monoamine Re-Uptake Inhibitor UWA-101 Improves Motor Fluctuations in the MPTP-Lesioned Common Marmoset  Thursday, September 20, 2012   More...
The Cardiac Ventricular 5-HT4 Receptor Is Functional in Late Foetal Development and Is Reactivated in Heart Failure  Thursday, September 20, 2012   More...
A Nested Case-Control Study of Intrauterine Exposure to Persistent Organochlorine Pollutants and the Risk of Hypospadias  Thursday, September 27, 2012   More...
Functional Characterisation of the WW Minimal Domain for Delivering Therapeutic Proteins by Adenovirus Dodecahedron  Thursday, September 27, 2012   More...
Anti-Inflammatory and Cardioprotective Effects of Tadalafil in Diabetic Mice  Friday, September 21, 2012   More...
Muscarinic Receptors in Amygdala Control Trace Fear Conditioning  Friday, September 21, 2012   More...
Identification of Novel Human Dipeptidyl Peptidase-IV Inhibitors of Natural Origin (Part II): In Silico Prediction in Antidiabetic Extracts  Friday, September 21, 2012   More...
Respiratory Paradoxical Adverse Drug Reactions Associated with Acetylcysteine and Carbocysteine Systemic Use in Paediatric Patients: A National Survey  Wednesday, July 27, 2011   More...
Genomic Regions Identified by Overlapping Clusters of Nominally-Positive SNPs from Genome-Wide Studies of Alcohol and Illegal Substance Dependence  Wednesday, July 27, 2011   More...
Metabolic Effects of Fluoxetine in Adults with Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Placebo-Controlled Trials  Thursday, July 28, 2011   More...
Evaluation of Un-Medicated, Self-Paced Alcohol Withdrawal  Thursday, July 28, 2011   More...
Inflammation and In-Stent Restenosis: The Role of Serum Markers and Stent Characteristics in Carotid Artery Stenting  Thursday, July 28, 2011   More...
Predicting P-Glycoprotein-Mediated Drug Transport Based On Support Vector Machine and Three-Dimensional Crystal Structure of P-glycoprotein  Tuesday, October 04, 2011   More...
Long-Stay Psychiatric Patients: A Prospective Study Revealing Persistent Antipsychotic-Induced Movement Disorder  Monday, October 03, 2011   More...
Effect of Sulindac Sulfide on Metallohydrolases in the Human Colon Cancer Cell Line HT-29  Monday, October 03, 2011   More...
Increased Risk for Invasive Breast Cancer Associated with Hormonal Therapy: A Nation-Wide Random Sample of 65,723 Women Followed from 1997 to 2008  Thursday, October 06, 2011   More...
Hyperforin Inhibits Akt1 Kinase Activity and Promotes Caspase-Mediated Apoptosis Involving Bad and Noxa Activation in Human Myeloid Tumor Cells  Thursday, October 06, 2011   More...
Identification of New Genes Involved in Human Adipogenesis and Fat Storage  Monday, February 27, 2012   More...
Comparative Gene Expression Profiling of P. falciparum Malaria Parasites Exposed to Three Different Histone Deacetylase Inhibitors  Monday, February 27, 2012   More...
(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice  Monday, February 27, 2012   More...
Core Site-Moiety Maps Reveal Inhibitors and Binding Mechanisms of Orthologous Proteins by Screening Compound Libraries  Wednesday, February 29, 2012   More...
Capacity for Absorption of Water-Soluble Secondary Metabolites Greater in Birds than in Rodents  Tuesday, February 28, 2012   More...
Suppression of FOXM1 Sensitizes Human Cancer Cells to Cell Death Induced by DNA-Damage  Wednesday, February 29, 2012   More...
Influence of IL28B Polymorphisms on Response to a Lower-Than-Standard Dose peg-IFN-a 2a for Genotype 3 Chronic Hepatitis C in HIV-Coinfected Patients  Tuesday, January 03, 2012   More...
Protective Effects of a Rhodiola Crenulata Extract and Salidroside on Hippocampal Neurogenesis against Streptozotocin-Induced Neural Injury in the Rat  Tuesday, January 03, 2012   More...
The Dopamine Augmenter L-DOPA Does Not Affect Positive Mood in Healthy Human Volunteers  Wednesday, January 04, 2012   More...
GW8510 Increases Insulin Expression in Pancreatic Alpha Cells through Activation of p53 Transcriptional Activity  Thursday, January 05, 2012   More...
Impedance Responses Reveal ß2-Adrenergic Receptor Signaling Pluridimensionality and Allow Classification of Ligands with Distinct Signaling Profiles  Thursday, January 05, 2012   More...
A Novel Strategy for Development of Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model  Friday, January 06, 2012   More...
Inhibition of Both Protease and Helicase Activities of Hepatitis C Virus NS3 by an Ethyl Acetate Extract of Marine Sponge Amphimedon sp  Wednesday, November 07, 2012   More...
Molecular Epidemiology of Human Immunodeficiency Virus Type 1 in Guangdong Province of Southern China  Wednesday, November 07, 2012   More...
Long-Term Survival in HIV Positive Patients with up to 15 Years of Antiretroviral Therapy  Wednesday, November 07, 2012   More...
Urine from Treated Cattle Drives Selection for Cephalosporin Resistant Escherichia coli in Soil  Wednesday, November 07, 2012   More...
Indocyanine Green-Assisted Internal Limiting Membrane Peeling in Macular Hole Surgery: A Meta-Analysis  Wednesday, November 07, 2012   More...
Low Dose Nicotine and Antagonism of ß2 Subunit Containing Nicotinic Acetylcholine Receptors Have Similar Effects on Affective Behavior in Mice  Wednesday, November 07, 2012   More...
Risk of Dementia in Patients with Insomnia and Long-term Use of Hypnotics: A Population-based Retrospective Cohort Study  Wednesday, November 07, 2012   More...
A Non-Synonymous Single Nucleotide Polymorphism in an OPRM1 Splice Variant Is Associated with Fentanyl-Induced Emesis in Women Undergoing Minor Gynaecological Surgery  Wednesday, November 07, 2012   More...
A Personalized BEST: Characterization of Latent Clinical Classes of Nonischemic Heart Failure That Predict Outcomes and Response to Bucindolol  Wednesday, November 07, 2012   More...
The Soluble Guanylyl Cyclase Activator Bay 58-2667 Selectively Limits Cardiomyocyte Hypertrophy  Wednesday, November 07, 2012   More...
Hypoxia-Inducible Factor Activation Protects the Kidney from Gentamicin-Induced Acute Injury  Thursday, November 08, 2012   More...
Effects of the CK2 Inhibitors CX-4945 and CX-5011 on Drug-Resistant Cells  Thursday, November 08, 2012   More...
Supplementation of Persimmon Leaf Ameliorates Hyperglycemia, Dyslipidemia and Hepatic Fat Accumulation in Type 2 Diabetic Mice  Thursday, November 08, 2012   More...
Differences in HCV Viral Decline between Low and Standard-Dose Pegylated-Interferon-Alpha-2a with Ribavirin in HIV/HCV Genotype 3 Patients  Thursday, November 08, 2012   More...
Activation of Haem-Oxidized Soluble Guanylyl Cyclase with BAY 60-2770 in Human Platelets Lead to Overstimulation of the Cyclic GMP Signaling Pathway  Thursday, November 08, 2012   More...
Identification of Anti-Malarial Compounds as Novel Antagonists to Chemokine Receptor CXCR4 in Pancreatic Cancer Cells  Friday, February 03, 2012   More...
Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination  Wednesday, February 08, 2012   More...
Cellular Growth Kinetics Distinguish a Cyclophilin Inhibitor from an HSP90 Inhibitor as a Selective Inhibitor of Hepatitis C Virus  Wednesday, February 08, 2012   More...
Over-Expression of a Cytochrome P450 Is Associated with Resistance to Pyriproxyfen in the Greenhouse Whitefly Trialeurodes vaporariorum  Wednesday, February 08, 2012   More...
Gene Expression Profiling of Dendritic Cells in Different Physiological Stages under Cordyceps sinensis Treatment  Thursday, July 19, 2012   More...
Immunotherapeutic Targeting of Membrane Hsp70-Expressing Tumors Using Recombinant Human Granzyme B  Thursday, July 19, 2012   More...
Effect of Intravitreal Anti-Vascular Endothelial Growth Factor Therapy on the Risk of Arterial Thromboembolic Events: A Meta-Analysis  Thursday, July 19, 2012   More...
Using Poison Center Exposure Calls to Predict Methadone Poisoning Deaths  Thursday, July 19, 2012   More...
Temporal Patterns of Medications Dispensed to Children and Adolescents in a National Insured Population  Thursday, July 19, 2012   More...
Bezafibrate for X-Linked Adrenoleukodystrophy  Friday, July 20, 2012   More...
An Acenocoumarol Dosing Algorithm Using Clinical and Pharmacogenetic Data in Spanish Patients with Thromboembolic Disease  Friday, July 20, 2012   More...
Staphylococcus aureus in Continuous Culture: A Tool for the Rational Design of Antibiotic Treatment Protocols  Friday, July 20, 2012   More...
Challenges in Coding Adverse Events in Clinical Trials: A Systematic Review  Friday, July 20, 2012   More...
Plant Extract Synthesized PLA Nanoparticles for Controlled and Sustained Release of Quercetin: A Green Approach  Monday, July 23, 2012   More...
A Naturally Occurring Hypoallergenic Variant of Vespid Antigen 5 from Polybia scutellaris Venom as a Candidate for Allergen-Specific Immunotherapy  Monday, July 23, 2012   More...
DIOL Triterpenes Block Profibrotic Effects of Angiotensin II and Protect from Cardiac Hypertrophy  Monday, July 23, 2012   More...
Guanidylation and Tail Effects in Cationic Antimicrobial Lipopeptoids  Monday, July 23, 2012   More...
Identifying Novel Drug Indications through Automated Reasoning  Monday, July 23, 2012   More...
Cost-Effectiveness of Peer-Delivered Interventions for Cocaine and Alcohol Abuse among Women: A Randomized Controlled Trial  Tuesday, March 20, 2012   More...
Folate Decorated Dual Drug Loaded Nanoparticle: Role of Curcumin in Enhancing Therapeutic Potential of Nutlin-3a by Reversing Multidrug Resistance  Wednesday, March 21, 2012   More...
Exploiting Adaptive Laboratory Evolution of Streptomyces clavuligerus for Antibiotic Discovery and Overproduction  Wednesday, March 21, 2012   More...
The p21-Dependent Radiosensitization of Human Breast Cancer Cells by MLN4924, an Investigational Inhibitor of NEDD8 Activating Enzyme  Thursday, March 22, 2012   More...
Maxadilan Prevents Apoptosis in iPS Cells and Shows No Effects on the Pluripotent State or Karyotype  Friday, March 23, 2012   More...
Computable Features Required to Evaluate the Efficacy of Drugs and a Universal Algorithm to Find Optimally Effective Drug in a Drug Complex  Friday, March 23, 2012   More...
Characterization of a FGF19 Variant with Altered Receptor Specificity Revealed a Central Role for FGFR1c in the Regulation of Glucose Metabolism  Friday, March 23, 2012   More...
Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/ß-Catenin Pathway  Friday, December 16, 2011   More...
The Endocrine Disruptor Mono-(2-Ethylhexyl) Phthalate Affects the Differentiation of Human Liposarcoma Cells (SW 872)  Wednesday, December 21, 2011   More...
Systematic Drug Repositioning Based on Clinical Side-Effects  Wednesday, December 21, 2011   More...
Novel Patient Cell-Based HTS Assay for Identification of Small Molecules for a Lysosomal Storage Disease  Wednesday, December 21, 2011   More...
Binding of Tetracycline and Chlortetracycline to the Enzyme Trypsin: Spectroscopic and Molecular Modeling Investigations  Monday, December 19, 2011   More...
A Fly in the Ointment: Evaluation of Traditional Use of Plants to Repel and Kill Blowfly Larvae in Fermented Fish  Monday, December 19, 2011   More...
Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays  Monday, December 19, 2011   More...
Mitragynine Attenuates Withdrawal Syndrome in Morphine-Withdrawn Zebrafish  Wednesday, December 21, 2011   More...
ACSL6 Is Associated with the Number of Cigarettes Smoked and Its Expression Is Altered by Chronic Nicotine Exposure  Tuesday, December 20, 2011   More...
Mechanisms of MEOX1 and MEOX2 Regulation of the Cyclin Dependent Kinase Inhibitors p21CIP1/WAF1 and p16INK4a in Vascular Endothelial Cells  Tuesday, December 20, 2011   More...
Molecular Mechanisms of Bortezomib Resistant Adenocarcinoma Cells  Thursday, December 22, 2011   More...
Safety and Reactogenicity of Canarypox ALVAC-HIV (vCP1521) and HIV-1 gp120 AIDSVAX B/E Vaccination in an Efficacy Trial in Thailand  Wednesday, December 21, 2011   More...
Chlorogenic Acid Stimulates Glucose Transport in Skeletal Muscle via AMPK Activation: A Contributor to the Beneficial Effects of Coffee on Diabetes  Wednesday, March 07, 2012   More...
5-Fluorouracil Induced Intestinal Mucositis via Nuclear Factor-?B Activation by Transcriptomic Analysis and In Vivo Bioluminescence Imaging  Wednesday, March 07, 2012   More...
Pre-Clinical Evaluation of a 213Bi-Labeled 2556 Antibody to HIV-1 gp41 Glycoprotein in HIV-1 Mouse Models as a Reagent for HIV Eradication  Friday, March 09, 2012   More...
Evidence for the Contribution of the Hemozoin Synthesis Pathway of the Murine Plasmodium yoelii to the Resistance to Artemisinin-Related Drugs  Monday, March 05, 2012   More...
Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture  Friday, January 27, 2012   More...
Plastic and Heritable Components of Phenotypic Variation in Nucella lapillus: An Assessment Using Reciprocal Transplant and Common Garden Experiments  Friday, January 27, 2012   More...
Interactive Effects of Large- and Small-Scale Sources of Feral Honey-Bees for Sunflower in the Argentine Pampas  Friday, January 27, 2012   More...
Consistent Pattern of Local Adaptation during an Experimental Heat Wave in a Pipefish-Trematode Host-Parasite System  Friday, January 27, 2012   More...
Synergistic TLR2/6 and TLR9 Activation Protects Mice against Lethal Influenza Pneumonia  Friday, January 27, 2012   More...
Induction of Heterosubtypic Cross-Protection against Influenza by a Whole Inactivated Virus Vaccine: The Role of Viral Membrane Fusion Activity  Friday, January 27, 2012   More...
Immunohistochemical Profile for Unknown Primary Adenocarcinoma  Friday, January 27, 2012   More...
Antibody to P. falciparum in Pregnancy Varies with Intermittent Preventive Treatment Regime and Bed Net Use  Friday, January 27, 2012   More...
Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models  Friday, January 27, 2012   More...
Interventions to Influence Consulting and Antibiotic Use for Acute Respiratory Tract Infections in Children: A Systematic Review and Meta-Analysis  Friday, January 27, 2012   More...
A Piezoelectric Immunosensor Using Hybrid Self-Assembled Monolayers for Detection of Schistosoma japonicum  Friday, January 27, 2012   More...
Patient's Origin and Lifestyle Associated with CTX-M-Producing Escherichia coli: A Case-Control-Control Study  Friday, January 27, 2012   More...
A Bovine Model of Respiratory Chlamydia psittaci Infection: Challenge Dose Titration  Friday, January 27, 2012   More...
Does a Family Meetings Intervention Prevent Depression and Anxiety in Family Caregivers of Dementia Patients? A Randomized Trial  Friday, January 27, 2012   More...
LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth  Friday, January 27, 2012   More...
MIR-99a and MIR-99b Modulate TGF-ß Induced Epithelial to Mesenchymal Plasticity in Normal Murine Mammary Gland Cells  Friday, January 27, 2012   More...
Reorganizing the Intrinsic Functional Architecture of the Human Primary Motor Cortex during Rest with Non-Invasive Cortical Stimulation  Friday, January 27, 2012   More...
The Cost of Universal Health Care in India: A Model Based Estimate  Friday, January 27, 2012   More...
Myocardial Alternative RNA Splicing and Gene Expression Profiling in Early Stage Hypoplastic Left Heart Syndrome  Friday, January 27, 2012   More...
ERK1 Regulates the Hematopoietic Stem Cell Niches  Monday, January 30, 2012   More...
Simulated Warming Differentially Affects the Growth and Competitive Ability of Centaurea maculosa Populations from Home and Introduced Ranges  Monday, January 30, 2012   More...
Seeing Emotion with Your Ears: Emotional Prosody Implicitly Guides Visual Attention to Faces  Monday, January 30, 2012   More...
CCL2 Is Associated with a Faster Rate of Cognitive Decline during Early Stages of Alzheimer's Disease  Monday, January 30, 2012   More...
Quality Control and Performance of HIV Rapid Tests in a Microbicide Clinical Trial in Rural KwaZulu-Natal  Monday, January 30, 2012   More...
Automated Workflow for Preparation of cDNA for Cap Analysis of Gene Expression on a Single Molecule Sequencer  Monday, January 30, 2012   More...
TBX21 and HLX1 Polymorphisms Influence Cytokine Secretion at Birth  Monday, January 30, 2012   More...
Metabolic Profiles and cDNA-AFLP Analysis of Salvia miltiorrhiza and Salvia castanea Diel f. tomentosa Stib  Monday, January 30, 2012   More...
An Ensemble Classifier for Eukaryotic Protein Subcellular Location Prediction Using Gene Ontology Categories and Amino Acid Hydrophobicity  Monday, January 30, 2012   More...
Catalog of MicroRNA Seed Polymorphisms in Vertebrates  Friday, January 27, 2012   More...
Access to Barrier Perches Improves Behavior Repertoire in Broilers  Friday, January 27, 2012   More...
Predicting Target DNA Sequences of DNA-Binding Proteins Based on Unbound Structures  Wednesday, February 01, 2012   More...
Environmentally Realistic Exposure to the Herbicide Atrazine Alters Some Sexually Selected Traits in Male Guppies  Wednesday, February 01, 2012   More...
Conditional Ablation of Ezh2 in Murine Hearts Reveals Its Essential Roles in Endocardial Cushion Formation, Cardiomyocyte Proliferation and Survival  Wednesday, February 01, 2012   More...
Responsiveness to 6-n-Propylthiouracil (PROP) Is Associated with Salivary Levels of Two Specific Basic Proline-Rich Proteins in Humans  Wednesday, February 01, 2012   More...
Viremic HIV Infected Individuals with High CD4 T Cells and Functional Envelope Proteins Show Anti-gp41 Antibodies with Unique Specificity and Function  Wednesday, February 01, 2012   More...
Implications of Extreme Life Span in Clonal Organisms: Millenary Clones in Meadows of the Threatened Seagrass Posidonia oceanica  Wednesday, February 01, 2012   More...
Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families  Wednesday, February 01, 2012   More...
In Silico Insights into the Symbiotic Nitrogen Fixation in Sinorhizobium meliloti via Metabolic Reconstruction  Wednesday, February 01, 2012   More...
Defining Plasmodium falciparum Treatment in South West Asia: A Randomized Trial Comparing Artesunate or Primaquine Combined with Chloroquine or SP  Tuesday, January 31, 2012   More...
Early Cell Death Detection with Digital Holographic Microscopy  Tuesday, January 31, 2012   More...
A Role for VEGFR2 Activation in Endothelial Responses Caused by Barrier Disruptive OxPAPC Concentrations  Tuesday, January 31, 2012   More...
A New Eusuchian Crocodyliform with Novel Cranial Integument and Its Significance for the Origin and Evolution of Crocodylia  Tuesday, January 31, 2012   More...
Increased Inter-Colony Fusion Rates Are Associated with Reduced COI Haplotype Diversity in an Invasive Colonial Ascidian Didemnum vexillum  Tuesday, January 31, 2012   More...
Ologs: A Categorical Framework for Knowledge Representation  Tuesday, January 31, 2012   More...
Primary Xenografts of Human Prostate Tissue as a Model to Study Angiogenesis Induced by Reactive Stroma  Tuesday, January 31, 2012   More...
Novel, Objective, Multivariate Biomarkers Composed of Plasma Amino Acid Profiles for the Diagnosis and Assessment of Inflammatory Bowel Disease  Tuesday, January 31, 2012   More...
Increased GABAA Receptor e-Subunit Expression on Ventral Respiratory Column Neurons Protects Breathing during Pregnancy  Tuesday, January 31, 2012   More...
Boolean Models of Biosurfactants Production in Pseudomonas fluorescens  Tuesday, January 31, 2012   More...
Homology Inference of Protein-Protein Interactions via Conserved Binding Sites  Tuesday, January 31, 2012   More...
The Risk of Stroke after Percutaneous Vertebroplasty for Osteoporosis: A Population-Based Cohort Study  Tuesday, January 31, 2012   More...
Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types  Wednesday, February 01, 2012   More...
Polyglutamine Repeats Are Associated to Specific Sequence Biases That Are Conserved among Eukaryotes  Wednesday, February 01, 2012   More...
Season of Sampling and Season of Birth Influence Serotonin Metabolite Levels in Human Cerebrospinal Fluid  Wednesday, February 01, 2012   More...
Eradication of Metastatic Renal Cell Carcinoma after Adenovirus-Encoded TNF-Related Apoptosis-Inducing Ligand (TRAIL)/CpG Immunotherapy  Wednesday, February 01, 2012   More...
Two-Item Sentence Comprehension by a Dog (Canis familiaris)  Wednesday, February 01, 2012   More...
Tobacco Rattle Virus Vector: A Rapid and Transient Means of Silencing Manduca sexta Genes by Plant Mediated RNA Interference  Wednesday, February 01, 2012   More...
Mitogen- and Stress-Activated Kinase 1 (MSK1) Regulates Cigarette Smoke-Induced Histone Modifications on NF-?B-dependent Genes  Wednesday, February 01, 2012   More...
Genetic Association Analysis Using Sibship Data: A Multilevel Model Approach  Wednesday, February 01, 2012   More...
Helicobacter pylori CagA Triggers Expression of the Bactericidal Lectin REG3? via Gastric STAT3 Activation  Wednesday, February 01, 2012   More...
Mimicry of Food Intake: The Dynamic Interplay between Eating Companions  Wednesday, February 01, 2012   More...
Innate Sex Differences in the Timing of Spring Migration in a Songbird  Wednesday, February 01, 2012   More...
Sleep Disorders and Demand for Medical Services: Evidence from a Population-Based Longitudinal Study  Wednesday, February 01, 2012   More...
Potent Phototoxicity of Marine Bunker Oil to Translucent Herring Embryos after Prolonged Weathering  Wednesday, February 01, 2012   More...
From Food to Offspring Down: Tissue-Specific Discrimination and Turn-Over of Stable Isotopes in Herbivorous Waterbirds and Other Avian Foraging Guilds  Wednesday, February 01, 2012   More...
Trans-Synaptic Spread of Tau Pathology In Vivo  Wednesday, February 01, 2012   More...
Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling  Wednesday, February 01, 2012   More...
NGS QC Toolkit: A Toolkit for Quality Control of Next Generation Sequencing Data  Wednesday, February 01, 2012   More...
Murine GRPR and Stathmin Control in Opposite Directions both Cued Fear Extinction and Neural Activities of the Amygdala and Prefrontal Cortex  Wednesday, February 01, 2012   More...
S-LOCUS EARLY FLOWERING 3 Is Exclusively Present in the Genomes of Short-Styled Buckwheat Plants that Exhibit Heteromorphic Self-Incompatibility  Wednesday, February 01, 2012   More...
Measuring the Impacts of Community-based Grasslands Management in Mongolia's Gobi  Wednesday, February 01, 2012   More...
Knowledge-Based Reconstruction of mRNA Transcripts with Short Sequencing Reads for Transcriptome Research  Wednesday, February 01, 2012   More...
CenSeam, an International Program on Seamounts within the Census of Marine Life: Achievements and Lessons Learned  Wednesday, February 01, 2012   More...
Can Phlorotannins Purified Extracts Constitute a Novel Pharmacological Alternative for Microbial Infections with Associated Inflammatory Conditions?  Thursday, February 02, 2012   More...
Activation and Inhibition of Transglutaminase 2 in Mice  Thursday, February 02, 2012   More...
Gu-4 Suppresses Affinity and Avidity Modulation of CD11b and Improves the Outcome of Mice with Endotoxemia and Sepsis  Thursday, February 02, 2012   More...
Lithium Treatment of APPSwDI/NOS2-/- Mice Leads to Reduced Hyperphosphorylated Tau, Increased Amyloid Deposition and Altered Inflammatory Phenotype  Thursday, February 09, 2012   More...
Caffeic Acid Phenethyl Ester and Its Amide Analogue Are Potent Inhibitors of Leukotriene Biosynthesis in Human Polymorphonuclear Leukocytes  Thursday, February 09, 2012   More...
Noradrenergic a1 Receptor Antagonist Treatment Attenuates Positive Subjective Effects of Cocaine in Humans: A Randomized Trial  Friday, February 03, 2012   More...
Toxicity Associated with Stavudine Dose Reduction from 40 to 30 mg in First-Line Antiretroviral Therapy  Monday, November 21, 2011   More...
Health Behaviors, Care Needs and Attitudes towards Self-Prescription: A Cross-Sectional Survey among Dutch Medical Students  Monday, November 21, 2011   More...
Prevalence of Antidepressant Prescription or Use in Patients with Acute Coronary Syndrome: A Systematic Review  Tuesday, November 22, 2011   More...
In Vitro Effects of Pirfenidone on Cardiac Fibroblasts: Proliferation, Myofibroblast Differentiation, Migration and Cytokine Secretion  Wednesday, November 23, 2011   More...
Which Compound to Select in Lead Optimization? Prospectively Validated Proteochemometric Models Guide Preclinical Development  Wednesday, November 23, 2011   More...
Lithium Monotherapy Increases ACTH and Cortisol Response in the Dex/CRH Test in Unipolar Depressed Subjects. A Study with 30 Treatment-Naive Patients  Wednesday, November 23, 2011   More...
Resistance Patterns Selected by Nevirapine vs. Efavirenz in HIV-Infected Patients Failing First-Line Antiretroviral Treatment: A Bayesian Analysis  Wednesday, November 23, 2011   More...
Molecular Determinants of Magnolol Targeting Both RXRa and PPAR?  Tuesday, November 29, 2011   More...
Peroxisome Proliferator-Activated Receptor-Gamma Agonists Suppress Tissue Factor Overexpression in Rat Balloon Injury Model with Paclitaxel Infusion  Tuesday, November 29, 2011   More...
Mangafodipir Protects against Hepatic Ischemia-Reperfusion Injury in Mice  Wednesday, November 02, 2011   More...
PLGA, PLGA-TMC and TMC-TPP Nanoparticles Differentially Modulate the Outcome of Nasal Vaccination by Inducing Tolerance or Enhancing Humoral Immunity  Wednesday, November 02, 2011   More...
Suicidal Behavior and Depression in Smoking Cessation Treatments  Wednesday, November 02, 2011   More...
Typologies of Prescription Opioid Use in a Large Sample of Adults Assessed for Substance Abuse Treatment  Wednesday, November 02, 2011   More...
ß-AR Blockers Suppresses ER Stress in Cardiac Hypertrophy and Heart Failure  Wednesday, November 02, 2011   More...
EGFR-Targeted Hybrid Plasmonic Magnetic Nanoparticles Synergistically Induce Autophagy and Apoptosis in Non-Small Cell Lung Cancer Cells  Monday, November 07, 2011   More...
Gene Expression-Based Chemical Genomics Identifies Potential Therapeutic Drugs in Hepatocellular Carcinoma  Monday, November 07, 2011   More...
Camphene, a Plant-Derived Monoterpene, Reduces Plasma Cholesterol and Triglycerides in Hyperlipidemic Rats Independently of HMG-CoA Reductase Activity  Thursday, November 03, 2011   More...
Unmasking Differential Effects of Rosiglitazone and Pioglitazone in the Combination Treatment with n-3 Fatty Acids in Mice Fed a High-Fat Diet  Thursday, November 03, 2011   More...
Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular Mechanisms  Tuesday, November 08, 2011   More...
A Two-Compartment Model of VEGF Distribution in the Mouse  Tuesday, November 08, 2011   More...
Context Mediates Antimicrobial Efficacy of Kinocidin Congener Peptide RP-1  Friday, November 04, 2011   More...
Perturbation of Host Cell Cytoskeleton by Cranberry Proanthocyanidins and Their Effect on Enteric Infections  Friday, November 04, 2011   More...
Urocortin-1 within the Centrally-Projecting Edinger-Westphal Nucleus Is Critical for Ethanol Preference  Friday, October 28, 2011   More...
Halofuginone Has Anti-Proliferative Effects in Acute Promyelocytic Leukemia by Modulating the Transforming Growth Factor Beta Signaling Pathway  Friday, October 28, 2011   More...
Expression of p53 in the Effects of Artesunate on Induction of Apoptosis and Inhibition of Proliferation in Rat Primary Hepatic Stellate Cells  Friday, October 28, 2011   More...
Transcriptional and Functional Analysis of the Effects of Magnolol: Inhibition of Autolysis and Biofilms in Staphylococcus aureus  Friday, October 28, 2011   More...
Association between Multi-Dose Drug Dispensing and Quality of Drug Treatment – A Register-Based Study  Monday, October 31, 2011   More...
Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis  Tuesday, November 01, 2011   More...
Activation of Sirt1 by Resveratrol Inhibits TNF-a Induced Inflammation in Fibroblasts  Tuesday, November 01, 2011   More...
An Inducible Cell-Cell Fusion System with Integrated Ability to Measure the Efficiency and Specificity of HIV-1 Entry Inhibitors  Tuesday, November 01, 2011   More...
Adjuvant Chemotherapy, with or without Taxanes, in Early or Operable Breast Cancer: A Meta-Analysis of 19 Randomized Trials with 30698 Patients  Tuesday, November 01, 2011   More...
Bilateral Fronto-Parietal Integrity in Young Chronic Cigarette Smokers: A Diffusion Tensor Imaging Study  Tuesday, November 01, 2011   More...
Calcium-Based Nanoparticles Accelerate Skin Wound Healing  Wednesday, November 02, 2011   More...
Rad51 and BRCA2 - New Molecular Targets for Sensitizing Glioma Cells to Alkylating Anticancer Drugs  Wednesday, November 02, 2011   More...
Predicting In Vivo Anti-Hepatofibrotic Drug Efficacy Based on In Vitro High-Content Analysis  Wednesday, November 02, 2011   More...
Rivastigmine Lowers Aß and Increases sAPPa Levels, Which Parallel Elevated Synaptic Markers and Metabolic Activity in Degenerating Primary Rat Neurons  Friday, July 22, 2011   More...
Levothyroxine Monotherapy Cannot Guarantee Euthyroidism in All Athyreotic Patients  Monday, August 01, 2011   More...
Impact of Small Body Weight on Tenofovir-Associated Renal Dysfunction in HIV-Infected Patients: A Retrospective Cohort Study of Japanese Patients  Monday, July 25, 2011   More...
Spherical Harmonics Coefficients for Ligand-Based Virtual Screening of Cyclooxygenase Inhibitors  Wednesday, July 27, 2011   More...
Proteomic Analysis Shows Synthetic Oleanane Triterpenoid Binds to mTOR  Wednesday, July 27, 2011   More...
Duloxetine Inhibits Effects of MDMA (“Ecstasy") In Vitro and in Humans in a Randomized Placebo-Controlled Laboratory Study  Friday, May 04, 2012   More...
Hypothalamic Orexin-A Neurons Are Involved in the Response of the Brain Stress System to Morphine Withdrawal  Wednesday, May 09, 2012   More...
Anti-Inflammatory Activities of Inotilone from Phellinus linteus through the Inhibition of MMP-9, NF-?B, and MAPK Activation In Vitro and In Vivo  Tuesday, May 08, 2012   More...
In Silico Assessment of Potential Druggable Pockets on the Surface of a1-Antitrypsin Conformers  Tuesday, May 08, 2012   More...
Pharmacogenetics Meets Metabolomics: Discovery of Tryptophan as a New Endogenous OCT2 Substrate Related to Metformin Disposition  Tuesday, May 08, 2012   More...
Gastrointestinal-Sparing Effects of Novel NSAIDs in Rats with Compromised Mucosal Defence  Monday, April 09, 2012   More...
White Matter Abnormalities Correlating with Memory and Depression in Heroin Users under Methadone Maintenance Treatment  Monday, April 09, 2012   More...
Effects of Smoking and Cessation on Subclinical Arterial Disease: A Substudy of a Randomized Controlled Trial  Monday, April 09, 2012   More...
Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells  Tuesday, April 10, 2012   More...
Identification of Critical Amino Acids in an Immunodominant IgE Epitope of Pen c 13, a Major Allergen from Penicillium citrinum  Tuesday, April 10, 2012   More...
Structural and Functional Diversity of Acidic Scorpion Potassium Channel Toxins  Thursday, April 12, 2012   More...
Proteomic Candidate Biomarkers of Drug-Induced Nephrotoxicity in the Rat  Wednesday, April 11, 2012   More...
Computational Modeling-Based Discovery of Novel Classes of Anti-Inflammatory Drugs That Target Lanthionine Synthetase C-Like Protein 2  Wednesday, April 11, 2012   More...
Beneficial Metabolic Effects of 2',3',5'-tri-acetyl-N6- (3-Hydroxylaniline) Adenosine in the Liver and Plasma of Hyperlipidemic Hamsters  Wednesday, March 28, 2012   More...
Characterization of Rhodamine-123 as a Tracer Dye for Use In In vitro Drug Transport Assays  Wednesday, March 28, 2012   More...
Chemoinformatic Identification of Novel Inhibitors against Mycobacterium tuberculosis L-aspartate a-decarboxylase  Wednesday, March 28, 2012   More...
Mesofluidic Devices for DNA-Programmed Combinatorial Chemistry  Thursday, March 29, 2012   More...
High Glucose Decreases Expression and Activity of p-glycoprotein in Cultured Human Retinal Pigment Epithelium Possibly through iNOS Induction  Friday, February 17, 2012   More...
Synthesis and Evaluation of a Series of 2-Substituted-5-Thiopropylpiperazine (Piperidine)-1,3,4-Oxadiazoles Derivatives as Atypical Antipsychotics  Monday, April 30, 2012   More...
Pharmacological Undertreatment of Coronary Risk Factors in Patients with Psoriasis: Observational Study of the Danish Nationwide Registries  Monday, April 30, 2012   More...
Treatment of Aspergillus fumigatus in Patients with Cystic Fibrosis: A Randomized, Placebo-Controlled Pilot Study  Monday, April 30, 2012   More...
Adult Neurogenesis Transiently Generates Oxidative Stress  Monday, April 30, 2012   More...
Antiproliferative Effects of DNA Methyltransferase 3B Depletion Are Not Associated with DNA Demethylation  Tuesday, May 01, 2012   More...
Ghrelin Treatment of Cachectic Patients with Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial  Tuesday, May 01, 2012   More...
Vagal Nerve Stimulation Rapidly Activates Brain-Derived Neurotrophic Factor Receptor TrkB in Rat Brain  Tuesday, May 01, 2012   More...
Smooth Muscle Myosin Inhibition: A Novel Therapeutic Approach for Pulmonary Hypertension  Tuesday, May 01, 2012   More...
Antimalarial Activity and Mechanisms of Action of Two Novel 4-Aminoquinolines against Chloroquine-Resistant Parasites  Wednesday, May 23, 2012   More...
Interaction of Virstatin with Human Serum Albumin: Spectroscopic Analysis and Molecular Modeling  Wednesday, May 23, 2012   More...
Differences in Rat Dorsal Striatal NMDA and AMPA Receptors following Acute and Repeated Cocaine-Induced Locomotor Activation  Thursday, May 24, 2012   More...
Continuous Regional Arterial Infusion with Fluorouracil and Octreotide Attenuates Severe Acute Pancreatitis in a Canine Model  Thursday, May 24, 2012   More...
Impact of Obesity on the Bioavailability of Peginterferon-a2a and Ribavirin and Treatment Outcome for Chronic Hepatitis C Genotype 2 or 3  Thursday, May 24, 2012   More...
Nilotinib Counteracts P-Glycoprotein-Mediated Multidrug Resistance and Synergizes the Antitumoral Effect of Doxorubicin in Soft Tissue Sarcomas  Friday, May 25, 2012   More...
A Policy-into-Practice Intervention to Increase the Uptake of Evidence-Based Management of Low Back Pain in Primary Care: A Prospective Cohort Study  Friday, May 25, 2012   More...
Genotype-Dependent Efficacy of a Dual PI3K/mTOR Inhibitor, NVP-BEZ235, and an mTOR Inhibitor, RAD001, in Endometrial Carcinomas  Friday, May 25, 2012   More...
Pan-Pathway Based Interaction Profiling of FDA-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism  Friday, May 25, 2012   More...
Early Warning Indicators for HIV Drug Resistance in Cameroon during the Year 2010  Thursday, May 17, 2012   More...
Pemetrexed plus Platinum as the First-Line Treatment Option for Advanced Non-Small Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials  Thursday, May 17, 2012   More...
Atomic Force Mechanobiology of Pluripotent Stem Cell-Derived Cardiomyocytes  Friday, May 18, 2012   More...
Efficacious Intermittent Dosing of a Novel JAK2 Inhibitor in Mouse Models of Polycythemia Vera  Friday, May 18, 2012   More...
Patient Organizations’ Funding from Pharmaceutical Companies: Is Disclosure Clear, Complete and Accessible to the Public? An Italian Survey  Wednesday, May 09, 2012   More...
Malabaricone-A Induces A Redox Imbalance That Mediates Apoptosis in U937 Cell Line  Thursday, May 10, 2012   More...
Perifosine as a Potential Novel Anti-Cancer Agent Inhibits EGFR/MET-AKT Axis in Malignant Pleural Mesothelioma  Thursday, May 10, 2012   More...
Impact of Low-Level-Viremia on HIV-1 Drug-Resistance Evolution among Antiretroviral Treated-Patients  Thursday, May 10, 2012   More...
cGMP-Phosphodiesterase Inhibition Enhances Photic Responses and Synchronization of the Biological Circadian Clock in Rodents  Thursday, May 10, 2012   More...
Hydrogen Sulfide Inhibits L-Type Calcium Currents Depending upon the Protein Sulfhydryl State in Rat Cardiomyocytes  Thursday, May 10, 2012   More...
Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding  Friday, May 11, 2012   More...
Suppression of the Nrf2-Dependent Antioxidant Response by Glucocorticoids and 11ß-HSD1-Mediated Glucocorticoid Activation in Hepatic Cells  Friday, May 11, 2012   More...
Ginkgolide B Reduces Atherogenesis and Vascular Inflammation in ApoE-/- Mice  Friday, May 11, 2012   More...
The Effect of Ketoconazole on Post-Burn Inflammation, Hypermetabolism and Clinical Outcomes  Friday, May 11, 2012   More...
Induction of Cellular Senescence by Doxorubicin Is Associated with Upregulated miR-375 and Induction of Autophagy in K562 Cells  Friday, May 11, 2012   More...
Genetic Polymorphisms in CYP2E1: Association with Schizophrenia Susceptibility and Risperidone Response in the Chinese Han Population  Friday, May 11, 2012   More...
Mechanisms Underlying the Link between Cannabis Use and Prospective Memory  Friday, May 11, 2012   More...
Cluster Analysis of Obesity and Asthma Phenotypes  Friday, May 11, 2012   More...
Clonidine Improved Laboratory-Measured Decision-Making Performance in Abstinent Heroin Addicts  Monday, January 23, 2012   More...
In Vitro and In Vivo Investigation of the Efficacy of Arylimidamide DB1831 and Its Mesylated Salt Form - DB1965 - against Trypanosoma cruzi Infection  Monday, January 23, 2012   More...
Pregnane X Receptor and Yin Yang 1 Contribute to the Differential Tissue Expression and Induction of CYP3A5 and CYP3A4  Monday, January 23, 2012   More...
“Members of the Same Club”: Challenges and Decisions Faced by US IRBs in Identifying and Managing Conflicts of Interest  Friday, July 29, 2011   More...
Symptoms after Ingestion of Pig Whipworm Trichuris suis Eggs in a Randomized Placebo-Controlled Double-Blind Clinical Trial  Tuesday, August 02, 2011   More...
Pregnancy and Virologic Response to Antiretroviral Therapy in South Africa  Tuesday, August 02, 2011   More...
Anti-Inflammatory Effect of Fluvastatin on IL-8 Production Induced by Pseudomonas aeruginosa and Aspergillus fumigatus Antigens in Cystic Fibrosis  Wednesday, August 03, 2011   More...
Functional Categories Associated with Clusters of Genes That Are Co-Expressed across the NCI-60 Cancer Cell Lines  Tuesday, January 24, 2012   More...
Genome-Wide Association Study of Copy Number Variants Suggests LTBP1 and FGD4 Are Important for Alcohol Drinking  Wednesday, January 25, 2012   More...
Inhibition of Wnt/ß-Catenin Signaling by a Soluble Collagen-Derived Frizzled Domain Interacting with Wnt3a and the Receptors Frizzled 1 and 8  Friday, January 27, 2012   More...
ISL1 Directly Regulates FGF10 Transcription during Human Cardiac Outflow Formation  Friday, January 27, 2012   More...
Differential Role of PKC-Induced c-Jun in HTLV-1 LTR Activation by 12-O-Tetradecanoylphorbol-13-acetate in Different Human T-cell Lines  Friday, January 27, 2012   More...
Busulphan-Cyclophosphamide Cause Endothelial Injury, Remodeling of Resistance Arteries and Enhanced Expression of Endothelial Nitric Oxide Synthase  Friday, January 27, 2012   More...
Effects of a Selective Cannabinoid CB2 Agonist and Antagonist on Intravenous Nicotine Self Administration and Reinstatement of Nicotine Seeking  Thursday, January 26, 2012   More...
The Polyamine Inhibitor Alpha-Difluoromethylornithine Modulates Hippocampus-Dependent Function after Single and Combined Injuries  Friday, January 27, 2012   More...
Non-Host Defense Response in a Novel Arabidopsis-Xanthomonas citri subsp. citri Pathosystem  Friday, January 27, 2012   More...
Drosophila KCNQ Channel Displays Evolutionarily Conserved Electrophysiology and Pharmacology with Mammalian KCNQ Channels  Wednesday, September 07, 2011   More...
Increased Expression of Cannabinoid CB1 Receptors in Achilles Tendinosis  Thursday, September 08, 2011   More...
A Novel System for Transcutaneous Application of Carbon Dioxide Causing an “Artificial Bohr Effect” in the Human Body  Thursday, September 08, 2011   More...
Investigating the Effect of Emetic Compounds on Chemotaxis in Dictyostelium Identifies a Non-Sentient Model for Bitter and Hot Tastant Research  Thursday, September 08, 2011   More...
A Selectable and Excisable Marker System for the Rapid Creation of Recombinant Poxviruses  Thursday, September 08, 2011   More...
A Randomized, Placebo Controlled, Double Masked Phase IB Study Evaluating the Safety and Antiviral Activity of Aprepitant, a Neurokinin-1 Receptor Antagonist in HIV-1 Infected Adults  Thursday, September 08, 2011   More...
Donepezil Impairs Memory in Healthy Older Subjects: Behavioural, EEG and Simultaneous EEG/fMRI Biomarkers  Thursday, September 08, 2011   More...
Bioluminescence-Based High-Throughput Screen Identifies Pharmacological Agents That Target Neurotransmitter Signaling in Small Cell Lung Carcinoma  Thursday, September 08, 2011   More...
Hepatic Xenobiotic Metabolizing Enzyme and Transporter Gene Expression through the Life Stages of the Mouse  Thursday, September 08, 2011   More...
In vivo Bioimaging as a Novel Strategy to Detect Doxorubicin-Induced Damage to Gonadal Blood Vessels  Friday, September 09, 2011   More...
Calcineurin-Inhibitor Minimization in Liver Transplant Patients with Calcineurin-Inhibitor-Related Renal Dysfunction: A Meta-Analysis  Friday, September 09, 2011   More...
Calculation of Direct Antiretroviral Treatment Costs and Potential Cost Savings by Using Generics in the German HIV ClinSurv Cohort  Friday, September 09, 2011   More...
Opiate Sensitization Induces FosB/?FosB Expression in Prefrontal Cortical, Striatal and Amygdala Brain Regions  Tuesday, August 23, 2011   More...
BPR1K653, a Novel Aurora Kinase Inhibitor, Exhibits Potent Anti-Proliferative Activity in MDR1 (P-gp170)-Mediated Multidrug-Resistant Cancer Cells  Wednesday, August 24, 2011   More...
High Density Lipoprotein Structural Changes and Drug Response in Lipidomic Profiles following the Long-Term Fenofibrate Therapy in the FIELD Substudy  Wednesday, August 24, 2011   More...
The Impact of Illicit Drug Use on Spontaneous Hepatitis C Clearance: Experience from a Large Cohort Population Study  Wednesday, August 24, 2011   More...
Diphenyl Difluoroketone: A Potent Chemotherapy Candidate for Human Hepatocellular Carcinoma  Thursday, August 25, 2011   More...
Sodium/myo-Inositol Transporters: Substrate Transport Requirements and Regional Brain Expression in the TgCRND8 Mouse Model of Amyloid Pathology  Friday, August 26, 2011   More...
Is Nitric Oxide Decrease Observed with Naphthoquinones in LPS Stimulated RAW 264.7 Macrophages a Beneficial Property?  Friday, August 26, 2011   More...
Albiglutide, a Long Lasting Glucagon-Like Peptide-1 Analog, Protects the Rat Heart against Ischemia/Reperfusion Injury: Evidence for Improving Cardiac Metabolic Efficiency  Friday, August 26, 2011   More...
Mobilisation of Hematopoietic CD34+ Precursor Cells in Patients with Acute Stroke Is Safe - Results of an Open-Labeled Non Randomized Phase I/II Trial  Friday, August 26, 2011   More...
The Influence of Genetic and Environmental Factors among MDMA Users in Cognitive Performance  Wednesday, November 16, 2011   More...
Paternal Cyclophosphamide Exposure Induces the Formation of Functional Micronuclei during the First Zygotic Division  Wednesday, November 16, 2011   More...
Inotropic Action of the Puberty Hormone Kisspeptin in Rat, Mouse and Human: Cardiovascular Distribution and Characteristics of the Kisspeptin Receptor  Tuesday, November 22, 2011   More...
Anticoagulants and the Propagation Phase of Thrombin Generation  Friday, November 18, 2011   More...
Effects of DPP-4 Inhibitors on the Heart in a Rat Model of Uremic Cardiomyopathy  Friday, November 18, 2011   More...
Decreased Spontaneous Eye Blink Rates in Chronic Cannabis Users: Evidence for Striatal Cannabinoid-Dopamine Interactions  Friday, November 18, 2011   More...
Interaction between Dysfunctional Connectivity at Rest and Heroin Cues-Induced Brain Responses in Male Abstinent Heroin-Dependent Individuals  Tuesday, October 18, 2011   More...
Benefit from B-Lymphocyte Depletion Using the Anti-CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study  Wednesday, October 19, 2011   More...
A Multi-Compartment, Single and Multiple Dose Pharmacokinetic Study of the Vaginal Candidate Microbicide 1% Tenofovir Gel  Wednesday, October 19, 2011   More...
Cues Paired with either Rapid or Slower Self-Administered Cocaine Injections Acquire Similar Conditioned Rewarding Properties  Wednesday, October 19, 2011   More...
Rac1-Regulated Endothelial Radiation Response Stimulates Extravasation and Metastasis That Can Be Blocked by HMG-CoA Reductase Inhibitors  Wednesday, October 19, 2011   More...
Acaricide Residues in Laying Hens Naturally Infested by Red Mite Dermanyssus gallinae  Tuesday, February 21, 2012   More...
The Prevalence and Cost of Unapproved Uses of Top-Selling Orphan Drugs  Tuesday, February 21, 2012   More...
Therapeutic Trial of Metformin and Bortezomib in a Mouse Model of Tuberous Sclerosis Complex (TSC)  Tuesday, February 21, 2012   More...
Arsenic Trioxide Exerts Antimyeloma Effects by Inhibiting Activity in the Cytoplasmic Substrates of Histone Deacetylase 6  Wednesday, February 22, 2012   More...
Novel MUC1 Aptamer Selectively Delivers Cytotoxic Agent to Cancer Cells In Vitro  Wednesday, February 22, 2012   More...
Adenovirus-5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part B: Safety, Immunogenicity and Protective Efficacy of the CSP Component  Friday, October 07, 2011   More...
Adenovirus Gene Transfer to Amelogenesis Imperfecta Ameloblast-Like Cells  Friday, October 07, 2011   More...
Modeling Pharmacodynamic Response to the Poly(ADP-Ribose) Polymerase Inhibitor ABT-888 in Human Peripheral Blood Mononuclear Cells  Monday, October 10, 2011   More...
Cost-Effectiveness of Angiotensin-Converting Enzyme Inhibitors for the Prevention of Diabetic Nephropathy in The Netherlands – A Markov Model  Tuesday, October 11, 2011   More...
Correlation versus Causation? Pharmacovigilance of the Analgesic Flupirtine Exemplifies the Need for Refined Spontaneous ADR Reporting  Tuesday, October 11, 2011   More...
Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition  Wednesday, November 30, 2011   More...
Engineered Single-Domain Antibodies with High Protease Resistance and Thermal Stability  Wednesday, November 30, 2011   More...
Novel Inhibitor Design for Hemagglutinin against H1N1 Influenza Virus by Core Hopping Method  Wednesday, November 30, 2011   More...
Establishing Long-Term Efficacy in Chronic Disease: Use of Recursive Partitioning and Propensity Score Adjustment to Estimate Outcome in MS  Wednesday, November 30, 2011   More...
Smart Drugs “As Common As Coffee”: Media Hype about Neuroenhancement  Wednesday, November 30, 2011   More...
IL-4 Deficiency Is Associated with Mechanical Hypersensitivity in Mice  Friday, December 02, 2011   More...
Lucanthone and Its Derivative Hycanthone Inhibit Apurinic Endonuclease-1 (APE1) by Direct Protein Binding  Thursday, September 15, 2011   More...
Involvement of the Glycogen Synthase Kinase-3 Signaling Pathway in TBI Pathology and Neurocognitive Outcome  Thursday, September 15, 2011   More...
Natural Form of Noncytolytic Flexible Human Fc as a Long-Acting Carrier of Agonistic Ligand, Erythropoietin  Friday, September 16, 2011   More...
Metabolomics-Driven Nutraceutical Evaluation of Diverse Green Tea Cultivars  Wednesday, August 10, 2011   More...
Production of a Bioengineered G-Protein Coupled Receptor of Human Formyl Peptide Receptor 3  Thursday, August 11, 2011   More...
Optimal Control of Hepatitis C Antiviral Treatment Programme Delivery for Prevention amongst a Population of Injecting Drug Users  Thursday, August 11, 2011   More...
Mast Cells Are Critical for Protection against Peptic Ulcers Induced by the NSAID Piroxicam  Friday, August 12, 2011   More...
Morbidity from Malaria in Children in the Year after They Had Received Intermittent Preventive Treatment of Malaria: A Randomised Trial  Friday, August 12, 2011   More...
The Role of RamA on the Development of Ciprofloxacin Resistance in Salmonella enterica Serovar Typhimurium  Friday, August 12, 2011   More...
Discovery of Prostamide F2a and Its Role in Inflammatory Pain and Dorsal Horn Nociceptive Neuron Hyperexcitability  Tuesday, February 21, 2012   More...
Ephrin-A1-Mediated Dopaminergic Neurogenesis and Angiogenesis in a Rat Model of Parkinson's Disease  Monday, February 20, 2012   More...
Regulation of MMP-9 by a WIN-Binding Site in the Monocyte-Macrophage System Independent from Cannabinoid Receptors  Tuesday, November 06, 2012   More...
Sub-Inhibitory Cefsulodin Sensitization of E. coli to ß-lactams Is Mediated by PBP1b Inhibition  Tuesday, November 06, 2012   More...
Methamphetamine Reduces Human Influenza A Virus Replication  Tuesday, November 06, 2012   More...
Cardioprotective Effect of Paeonol and Danshensu Combination on Isoproterenol-Induced Myocardial Injury in Rats  Tuesday, November 06, 2012   More...
In Vitro and In Vivo Activity of an Organic Tellurium Compound on Leishmania (Leishmania) chagasi  Wednesday, November 07, 2012   More...
Enhanced Antitumor Efficacy and Reduced Systemic Toxicity of Sulfatide-Containing Nanoliposomal Doxorubicin in a Xenograft Model of Colorectal Cancer  Wednesday, November 07, 2012   More...
Caprylic Triglyceride as a Novel Therapeutic Approach to Effectively Improve the Performance and Attenuate the Symptoms Due to the Motor Neuron Loss in ALS Disease  Wednesday, November 07, 2012   More...
Lysosomotropic Properties of Weakly Basic Anticancer Agents Promote Cancer Cell Selectivity In Vitro  Wednesday, November 07, 2012   More...
Diminazene Aceturate (Berenil) Modulates the Host Cellular and Inflammatory Responses to Trypanosoma congolense Infection  Wednesday, November 07, 2012   More...
Artemisinin Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Inhibiting NF-?B Pathway in Microglia Cells  Friday, April 13, 2012   More...
Complement C1 Esterase Inhibitor Levels Linked to Infections and Contaminated Heparin-Associated Adverse Events  Friday, April 13, 2012   More...
Reaching the Hard-to-Reach: A Probability Sampling Method for Assessing Prevalence of Driving under the Influence after Drinking in Alcohol Outlets  Friday, April 13, 2012   More...
The Effect of Chronic Antipsychotic Drug on Hypothalamic Expression of Neural Nitric Oxide Synthase and Dopamine D2 Receptor in the Male Rat  Friday, April 13, 2012   More...
Loop Diuretics Have Anxiolytic Effects in Rat Models of Conditioned Anxiety  Friday, April 13, 2012   More...
Repeated Methamphetamine Administration Differentially Alters Fos Expression in Caudate-Putamen Patch and Matrix Compartments and Nucleus Accumbens  Friday, April 13, 2012   More...
Caffeine Consumption Prevents Diabetes-Induced Memory Impairment and Synaptotoxicity in the Hippocampus of NONcZNO10/LTJ Mice  Friday, April 13, 2012   More...
Interaction of Aspirin (Acetylsalicylic Acid) with Lipid Membranes  Tuesday, April 17, 2012   More...
Proteins from Avastin® (bevacizumab) Show Tyrosine Nitrations for which the Consequences Are Completely Unclear  Monday, April 16, 2012   More...
1,2-Octanediol, a Novel Surfactant, for Treating Head Louse Infestation: Identification of Activity, Formulation, and Randomised, Controlled Trials  Monday, April 16, 2012   More...
Adverse Events of Interferon Beta-1a: A Prospective Multi-Centre International ICH-GCP-Based CRO-Supported External Validation Study in Daily Practice  Tuesday, October 25, 2011   More...
Increasing Antiproliferative Properties of Endocannabinoids in N1E-115 Neuroblastoma Cells through Inhibition of Their Metabolism  Thursday, October 27, 2011   More...
Nebulisation of Receptor-Targeted Nanocomplexes for Gene Delivery to the Airway Epithelium  Wednesday, October 26, 2011   More...
Impact of Definitive Therapy with Beta-Lactam Monotherapy or Combination with an Aminoglycoside or a Quinolone for Pseudomonas aeruginosa Bacteremia  Wednesday, October 26, 2011   More...
Effects of Short-Term Continuous Subcutaneous Insulin Infusion on Fasting Plasma Fibroblast Growth Factor-21 Levels in Patients with Newly Diagnosed Type 2 Diabetes Mellitus  Wednesday, October 26, 2011   More...
Reversal of Fragile X Phenotypes by Manipulation of AßPP/Aß Levels in Fmr1KO Mice  Wednesday, October 26, 2011   More...
Protective Role of Hydrogen Sulfide against Noise-Induced Cochlear Damage: A Chronic Intracochlear Infusion Model  Wednesday, October 26, 2011   More...
Differential Effects of Accumbens Core vs. Shell Lesions in a Rat Concurrent Conditioned Place Preference Paradigm for Cocaine vs. Social Interaction  Wednesday, October 26, 2011   More...
Cost-Effectiveness of Pharmacotherapy to Reduce Obesity  Thursday, October 27, 2011   More...
Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27  Monday, October 31, 2011   More...
Nevirapine Plasma Concentrations Are Associated with Virologic Response and Hepatotoxicity in Chinese Patients with HIV Infection  Monday, October 31, 2011   More...
Differential Modulation of Beta-Adrenergic Receptor Signaling by Trace Amine-Associated Receptor 1 Agonists  Monday, October 31, 2011   More...
Vaccination of Lactating Dairy Cows for the Prevention of Aflatoxin B1 Carry Over in Milk  Friday, October 28, 2011   More...
Oleanolic Acid Initiates Apoptosis in Non-Small Cell Lung Cancer Cell Lines and Reduces Metastasis of a B16F10 Melanoma Model In Vivo  Friday, December 09, 2011   More...
Cochrane Systematic Reviews of Chinese Herbal Medicines: An Overview  Friday, December 09, 2011   More...
Development of Derivatives of 3, 3'-Diindolylmethane as Potent Leishmania donovani Bi-Subunit Topoisomerase IB Poisons  Monday, December 12, 2011   More...
Identifying HER2 Inhibitors from Natural Products Database  Monday, December 12, 2011   More...
Bisbibenzyls, a New Type of Antifungal Agent, Inhibit Morphogenesis Switch and Biofilm Formation through Upregulation of DPP3 in Candida albicans  Monday, December 12, 2011   More...
The Antidiabetic Drug Ciglitazone Induces High Grade Bladder Cancer Cells Apoptosis through the Up-Regulation of TRAIL  Monday, December 12, 2011   More...
In silico Analysis of Conformational Changes Induced by Mutation of Aromatic Binding Residues: Consequences for Drug Binding in the hERG K+ Channel  Thursday, December 15, 2011   More...
Checkpoint Signaling, Base Excision Repair, and PARP Promote Survival of Colon Cancer Cells Treated with 5-Fluorodeoxyuridine but Not 5-Fluorouracil  Thursday, December 15, 2011   More...
Antihypertensive Treatment Differentially Affects Vascular Sphingolipid Biology in Spontaneously Hypertensive Rats  Thursday, December 15, 2011   More...
Endemic Acinetobacter baumannii in a New York Hospital  Tuesday, December 13, 2011   More...
Additive Antinociceptive Effects of a Combination of Vitamin C and Vitamin E after Peripheral Nerve Injury  Wednesday, December 14, 2011   More...
A Novel Peptide Derived from Human Pancreatitis-Associated Protein Inhibits Inflammation In Vivo and In Vitro and Blocks NF-Kappa B Signaling Pathway  Wednesday, December 14, 2011   More...
Intraocular Pressure Changes: An Important Determinant of the Biocompatibility of Intravitreous Implants  Wednesday, December 14, 2011   More...
Thiopurine Methyltransferase Predicts the Extent of Cytotoxicty and DNA Damage in Astroglial Cells after Thioguanine Exposure  Wednesday, December 21, 2011   More...
Acid Solution Is a Suitable Medium for Introducing QX-314 into Nociceptors through TRPV1 Channels to Produce Sensory-Specific Analgesic Effects  Wednesday, December 28, 2011   More...
Differential Effects of Pravastatin and Simvastatin on the Growth of Tumor Cells from Different Organ Sites  Thursday, December 22, 2011   More...
Identification of New Alleles and the Determination of Alleles and Genotypes Frequencies at the CYP2D6 Gene in Emiratis  Thursday, December 22, 2011   More...
Safety of Postoperative Administration of Human Urinary Trypsin Inhibitor in Lung Cancer Patients with Idiopathic Pulmonary Fibrosis  Thursday, December 22, 2011   More...
Cardiovascular Agents Affect the Tone of Pulmonary Arteries and Veins in Precision-Cut Lung Slices  Tuesday, December 27, 2011   More...
Substance-Related Health Problems during Rave Parties in the Netherlands (1997–2008)  Wednesday, December 28, 2011   More...
Quality of Reporting of Bioequivalence Trials Comparing Generic to Brand Name Drugs: A Methodological Systematic Review  Wednesday, August 17, 2011   More...
Optimised and Rapid Pre-clinical Screening in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)  Thursday, August 18, 2011   More...
The Astrocyte-Targeted Therapy by Bushi for the Neuropathic Pain in Mice  Thursday, August 18, 2011   More...
Functional Insight into the C-Terminal Extension of Halolysin SptA from Haloarchaeon Natrinema sp. J7  Friday, August 19, 2011   More...
Pilot, Randomized Study Assessing Safety, Tolerability and Efficacy of Simplified LPV/r Maintenance Therapy in HIV Patients on the 1st PI-Based Regimen  Friday, August 19, 2011   More...
Molecular Sites for the Positive Allosteric Modulation of Glycine Receptors by Endocannabinoids  Thursday, August 25, 2011   More...
Comprehensive Study in the Inhibitory Effect of Berberine on Gene Transcription, Including TATA Box  Monday, August 22, 2011   More...
A Pilot Randomised Trial of Induced Blood-Stage Plasmodium falciparum Infections in Healthy Volunteers for Testing Efficacy of New Antimalarial Drugs  Monday, August 22, 2011   More...
Curcumin-Loaded Apotransferrin Nanoparticles Provide Efficient Cellular Uptake and Effectively Inhibit HIV-1 Replication In Vitro  Monday, August 22, 2011   More...
Novel Binding Mode of a Potent and Selective Tankyrase Inhibitor  Friday, March 16, 2012   More...
Reversal of Cocaine-Conditioned Place Preference through Methyl Supplementation in Mice: Altering Global DNA Methylation in the Prefrontal Cortex  Friday, March 16, 2012   More...
Enhanced Interleukin-1 Activity Contributes to Exercise Intolerance in Patients with Systolic Heart Failure  Friday, March 16, 2012   More...
Prediction of Promiscuous P-Glycoprotein Inhibition Using a Novel Machine Learning Scheme  Friday, March 16, 2012   More...
Quantitative Proteome Profiling of C. burnetii under Tetracycline Stress Conditions  Friday, March 16, 2012   More...
Down-Regulation of Glucose-Regulated Protein (GRP) 78 Potentiates Cytotoxic Effect of Celecoxib in Human Urothelial Carcinoma Cells  Friday, March 16, 2012   More...
Investigation of Indazole Unbinding Pathways in CYP2E1 by Molecular Dynamics Simulations  Monday, March 19, 2012   More...
Moderate Antiproteinuric Effect of Add-On Aldosterone Blockade with Eplerenone in Non-Diabetic Chronic Kidney Disease. A Randomized Cross-Over Study  Friday, November 04, 2011   More...
Effects of Vitamin D Supplementation on Cognitive and Emotional Functioning in Young Adults – A Randomised Controlled Trial  Friday, November 04, 2011   More...
Regional Grey and White Matter Changes in Heavy Male Smokers  Friday, November 04, 2011   More...
Metabolic Patterns and Biotransformation Activities of Resveratrol in Human Glioblastoma Cells: Relevance with Therapeutic Efficacies  Friday, November 11, 2011   More...
A Novel, Functional and Replicable Risk Gene Region for Alcohol Dependence Identified by Genome-Wide Association Study  Monday, November 07, 2011   More...
Suppression of Expression of Heat Shock Protein 70 by Gefitinib and Its Contribution to Pulmonary Fibrosis  Wednesday, November 09, 2011   More...
Everolimus and Sirolimus in Combination with Cyclosporine Have Different Effects on Renal Metabolism in the Rat  Wednesday, October 31, 2012   More...
A Phage Display Selected 7-mer Peptide Inhibitor of the Tannerella forsythia Metalloprotease-Like Enzyme Karilysin can be Truncated to Ser-Trp-Phe-Pro  Wednesday, October 31, 2012   More...
Targeting 3-Phosphoinoside-Dependent Kinase-1 to Inhibit Insulin-Like Growth Factor-I Induced AKT and p70 S6 Kinase Activation in Breast Cancer Cells  Wednesday, October 31, 2012   More...
Modeling 18F-FDG Kinetics during Acute Lung Injury: Experimental Data and Estimation Errors  Wednesday, October 31, 2012   More...
Scaffold-Based Pan-Agonist Design for the PPARa, PPARß and PPAR? Receptors  Wednesday, October 31, 2012   More...
Clinical Presentations, Antiplatelet Strategies and Prognosis of Patients with Stent Thrombosis: An Observational Study of 140 Patients  Wednesday, October 31, 2012   More...
In Vivo and In Vitro Suppression of Hepatocellular Carcinoma by EF24, a Curcumin Analog  Wednesday, October 31, 2012   More...
Alcohol Affects the Brain's Resting-State Network in Social Drinkers  Wednesday, October 31, 2012   More...
Comparison of Suprachoroidal Drug Delivery with Subconjunctival and Intravitreal Routes Using Noninvasive Fluorophotometry  Wednesday, October 31, 2012   More...
H1-Antihistamine Up-Dosing in Chronic Spontaneous Urticaria: Patients' Perspective of Effectiveness and Side Effects – A Retrospective Survey Study  Thursday, September 01, 2011   More...
Enhanced Transferrin Receptor Expression by Proinflammatory Cytokines in Enterocytes as a Means for Local Delivery of Drugs to Inflamed Gut Mucosa  Tuesday, September 06, 2011   More...
Hepatotoxicity or Hepatoprotection? Pattern Recognition for the Paradoxical Effect of the Chinese Herb Rheum palmatum L. in Treating Rat Liver Injury  Tuesday, September 06, 2011   More...
Effects and Action Mechanisms of Berberine and Rhizoma coptidis on Gut Microbes and Obesity in High-Fat Diet-Fed C57BL/6J Mice  Tuesday, September 06, 2011   More...
Multicenter Phase 2 Trial of Sirolimus for Tuberous Sclerosis: Kidney Angiomyolipomas and Other Tumors Regress and VEGF- D Levels Decrease  Tuesday, September 06, 2011   More...
Meta-Analysis of the Immunogenicity and Tolerability of Pandemic Influenza A 2009 (H1N1) Vaccines  Tuesday, September 06, 2011   More...
Sustained Release of an Anti-Glaucoma Drug: Demonstration of Efficacy of a Liposomal Formulation in the Rabbit Eye  Friday, September 09, 2011   More...
Gene Expression Signature Analysis Identifies Vorinostat as a Candidate Therapy for Gastric Cancer  Friday, September 09, 2011   More...
Association between Single Nucleotide Polymorphisms (SNPs) and Toxicity of Advanced Non-Small-Cell Lung Cancer Patients Treated with Chemotherapy  Wednesday, October 31, 2012   More...
Total Beta-Adrenoceptor Knockout Slows Conduction and Reduces Inducible Arrhythmias in the Mouse Heart  Thursday, November 01, 2012   More...
Variants Identified in a GWAS Meta-Analysis for Blood Lipids Are Associated with the Lipid Response to Fenofibrate  Wednesday, October 31, 2012   More...
Pioglitazone Improves In Vitro Viability and Function of Endothelial Progenitor Cells from Individuals with Impaired Glucose Tolerance  Monday, November 05, 2012   More...
Pharmacogenetics of Efficacy and Safety of HCV Treatment in HCV-HIV Coinfected Patients: Significant Associations with IL28B and SOCS3 Gene Variants  Friday, November 02, 2012   More...
Sigma-1 Receptor Agonists Directly Inhibit NaV1.2/1.4 Channels  Monday, November 05, 2012   More...
Identification of Novel HIV 1- Protease Inhibitors: Application of Ligand and Structure Based Pharmacophore Mapping and Virtual Screening  Thursday, November 08, 2012   More...
The Nonantibiotic Small Molecule Cyslabdan Enhances the Potency of ß-Lactams against MRSA by Inhibiting Pentaglycine Interpeptide Bridge Synthesis  Tuesday, November 06, 2012   More...
Efficacy of Single-Dose and Triple-Dose Albendazole and Mebendazole against Soil-Transmitted Helminths and Taenia spp.: A Randomized Controlled Trial  Tuesday, September 27, 2011   More...
Prenatal Cocaine Exposure Increases Synaptic Localization of a Neuronal RasGEF, GRASP-1 via Hyperphosphorylation of AMPAR Anchoring Protein, GRIP  Tuesday, September 27, 2011   More...
Synergistic Inhibition of Endothelial Cell Proliferation, Tube Formation, and Sprouting by Cyclosporin A and Itraconazole  Wednesday, September 28, 2011   More...
Atorvastatin Therapy during the Peri-Infarct Period Attenuates Left Ventricular Dysfunction and Remodeling after Myocardial Infarction  Wednesday, September 28, 2011   More...
Reversible Resistance Induced by FLT3 Inhibition: A Novel Resistance Mechanism in Mutant FLT3-Expressing Cells  Wednesday, September 28, 2011   More...
Enrollment Characteristics and Risk Behaviors of Injection Drug Users Participating in the Bangkok Tenofovir Study, Thailand  Wednesday, September 28, 2011   More...
High-Throughput Screen for Identifying Small Molecules That Target Fungal Zinc Homeostasis  Thursday, September 29, 2011   More...
The Novel Gamma Secretase Inhibitor RO4929097 Reduces the Tumor Initiating Potential of Melanoma  Thursday, September 29, 2011   More...
Disease Severity and Progression in Progressive Supranuclear Palsy and Multiple System Atrophy: Validation of the NNIPPS – PARKINSON PLUS SCALE  Thursday, August 04, 2011   More...
Adverse Events Following Pandemic A (H1N1) 2009 Monovalent Vaccines in Pregnant Women — Taiwan, November 2009–August 2010  Friday, August 05, 2011   More...
Mytilus galloprovincialis Myticin C: A Chemotactic Molecule with Antiviral Activity and Immunoregulatory Properties  Monday, August 08, 2011   More...
Treatment Interruption and Variation in Tablet Taking Behaviour Result in Viral Failure: A Case-Control Study from Cape Town, South Africa  Monday, August 08, 2011   More...
A Double Blind, Placebo-Controlled, Randomized Crossover Study of the Acute Metabolic Effects of Olanzapine in Healthy Volunteers  Tuesday, August 09, 2011   More...
Anti-Angiogenic and Anti-Inflammatory Properties of Kahweol, a Coffee Diterpene  Tuesday, August 09, 2011   More...
The Effect of the Potential PhoQ Histidine Kinase Inhibitors on Shigella flexneri Virulence  Wednesday, August 10, 2011   More...
BTZO-15, an ARE-Activator, Ameliorates DSS- and TNBS-Induced Colitis in Rats  Wednesday, August 10, 2011   More...
Implication of Glutathione in the In Vitro Antiplasmodial Mechanism of Action of Ellagic Acid  Friday, September 28, 2012   More...
H(2)S-Releasing Aspirin Protects against Aspirin-Induced Gastric Injury via Reducing Oxidative Stress  Friday, September 28, 2012   More...
Protective Effects of Polydatin from Polygonum cuspidatum against Carbon Tetrachloride-Induced Liver Injury in Mice  Friday, September 28, 2012   More...
LXR-Mediated Inhibition of CD4+ T Helper Cells  Friday, September 28, 2012   More...
Study of Natural Health Product Adverse Reactions (SONAR): Active Surveillance of Adverse Events Following Concurrent Natural Health Product and Prescription Drug Use in Community Pharmacies  Friday, September 28, 2012   More...
Comparison of Optical and Power Doppler Ultrasound Imaging for Non-Invasive Evaluation of Arsenic Trioxide as a Vascular Disrupting Agent in Tumors  Friday, September 28, 2012   More...
AZD1480 Blocks Growth and Tumorigenesis of RET- Activated Thyroid Cancer Cell Lines  Tuesday, October 02, 2012   More...
Select Small Core Structure Carbamates Exhibit High Contact Toxicity to “Carbamate-Resistant” Strain Malaria Mosquitoes, Anopheles gambiae (Akron)  Monday, October 01, 2012   More...
Recombinant Adiponectin Does Not Lower Plasma Glucose in Animal Models of Type 2 Diabetes  Monday, October 01, 2012   More...
Maximal Load of the Vitamin B12 Transport System: A Study on Mice Treated for Four Weeks with High-Dose Vitamin B12 or Cobinamide  Monday, October 01, 2012   More...
A Systems Approach for Tumor Pharmacokinetics  Wednesday, September 14, 2011   More...
MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma  Monday, September 12, 2011   More...
Environmental Levels of the Antiviral Oseltamivir Induce Development of Resistance Mutation H274Y in Influenza A/H1N1 Virus in Mallards  Monday, September 12, 2011   More...
Cilostazol Activates Function of Bone Marrow-Derived Endothelial Progenitor Cell for Re-endothelialization in a Carotid Balloon Injury Model  Monday, September 12, 2011   More...
In Vitro Evolution of Allergy Vaccine Candidates, with Maintained Structure, but Reduced B Cell and T Cell Activation Capacity  Tuesday, September 13, 2011   More...
Styryl-Based and Tricyclic Compounds as Potential Anti-Prion Agents  Tuesday, September 13, 2011   More...
Statins Enhance Clonal Growth of Late Outgrowth Endothelial Progenitors and Increase Myocardial Capillary Density in the Chronically Ischemic Heart  Tuesday, September 13, 2011   More...
Immunosuppressive Treatment for Nephrotic Idiopathic Membranous Nephropathy: A Meta-Analysis Based on Chinese Adults  Wednesday, September 05, 2012   More...
Towards Measuring Brain Function on Groups of People in the Real World  Wednesday, September 05, 2012   More...
Differential Effects of Short-Term Treatment with Two AT1 Receptor Blockers on Diameter of Pial Arterioles in SHR  Wednesday, September 05, 2012   More...
Phototriggerable 2',7-Caged Paclitaxel  Thursday, September 06, 2012   More...
Docosahexaenoic Acid for Reading, Cognition and Behavior in Children Aged 7–9 Years: A Randomized, Controlled Trial (The DOLAB Study)  Thursday, September 06, 2012   More...
SU5416, a VEGF Receptor Inhibitor and Ligand of the AHR, Represents a New Alternative for Immunomodulation  Thursday, September 06, 2012   More...
Development of Multicellular Tumor Spheroid (MCTS) Culture from Breast Cancer Cell and a High Throughput Screening Method Using the MTT Assay  Thursday, September 06, 2012   More...
Safety and Tolerability of Lactobacillus reuteri DSM 17938 and Effects on Biomarkers in Healthy Adults: Results from a Randomized Masked Trial  Thursday, September 06, 2012   More...
Bone Marrow-Derived Mesenchymal Stem Cells Repaired but Did Not Prevent Gentamicin-Induced Acute Kidney Injury through Paracrine Effects in Rats  Thursday, September 06, 2012   More...
a-Tomatine-Mediated Anti-Cancer Activity In Vitro and In Vivo through Cell Cycle- and Caspase-Independent Pathways  Thursday, September 06, 2012   More...
Identification of PPARgamma Partial Agonists of Natural Origin (I): Development of a Virtual Screening Procedure and In Vitro Validation  Friday, November 30, 2012   More...
Discovery of a Novel, Monocationic, Small-Molecule Inhibitor of Scrapie Prion Accumulation in Cultured Sheep Microglia and Rov Cells  Friday, November 30, 2012   More...
Nicotine Reward and Affective Nicotine Withdrawal Signs Are Attenuated in Calcium/Calmodulin-Dependent Protein Kinase IV Knockout Mice  Friday, November 30, 2012   More...
Lipid-Lowering Effects of Tetradecylthioacetic Acid in Antipsychotic-Exposed, Female Rats: Challenges with Long-Term Treatment  Friday, November 30, 2012   More...
Impact of Individual and Environmental Socioeconomic Status on Peritoneal Dialysis Outcomes: A Retrospective Multicenter Cohort Study  Friday, November 30, 2012   More...
Evaluation of Peripheral Blood Mononuclear Cell Processing and Analysis for Survival Motor Neuron Protein  Friday, November 30, 2012   More...
Functional Analysis of Plasmodium vivax Dihydrofolate Reductase-Thymidylate Synthase Genes through Stable Transformation of Plasmodium falciparum  Monday, July 09, 2012   More...
The Loss of Metabolic Control on Alcohol Drinking in Heavy Drinking Alcohol-Dependent Subjects  Monday, July 09, 2012   More...
The Interplay of Lung Surfactant Proteins and Lipids Assimilates the Macrophage Clearance of Nanoparticles  Tuesday, July 10, 2012   More...
Cold Storage of Rat Hepatocyte Suspensions for One Week in a Customized Cold Storage Solution – Preservation of Cell Attachment and Metabolism  Monday, July 09, 2012   More...
Capture, Anesthesia, and Disturbance of Free-Ranging Brown Bears (Ursus arctos) during Hibernation  Monday, July 16, 2012   More...
Systems Biological Approach of Molecular Descriptors Connectivity: Optimal Descriptors for Oral Bioavailability Prediction  Monday, July 16, 2012   More...
Prediction of Chemical-Protein Interactions Network with Weighted Network-Based Inference Method  Monday, July 16, 2012   More...
Tamoxifen-Induced Epigenetic Silencing of Oestrogen-Regulated Genes in Anti-Hormone Resistant Breast Cancer  Tuesday, July 10, 2012   More...
A Novel Flow Cytometric HTS Assay Reveals Functional Modulators of ATP Binding Cassette Transporter ABCB6  Tuesday, July 10, 2012   More...
Splicing of the rSlo Gene Affects the Molecular Composition and Drug Response of Ca2+-Activated K+ Channels in Skeletal Muscle  Tuesday, July 10, 2012   More...
Inactivation of Candida Biofilms by Non-Thermal Plasma and Its Enhancement for Fungistatic Effect of Antifungal Drugs  Tuesday, July 10, 2012   More...
Effects of Acute MDMA Intoxication on Mood and Impulsivity: Role of the 5-HT2 and 5-HT1 Receptors  Tuesday, July 10, 2012   More...
Crowd Sourcing a New Paradigm for Interactome Driven Drug Target Identification in Mycobacterium tuberculosis  Wednesday, July 11, 2012   More...
Energetics of Ortho-7 (Oxime Drug) Translocation through the Active-Site Gorge of Tabun Conjugated Acetylcholinesterase  Wednesday, July 11, 2012   More...
Hydrogen Sulfide Suppresses Outward Rectifier Potassium Currents in Human Pluripotent Stem Cell-Derived Cardiomyocytes  Friday, November 30, 2012   More...
Withaferin A Induces Proteasome Inhibition, Endoplasmic Reticulum Stress, the Heat Shock Response and Acquisition of Thermotolerance  Friday, November 30, 2012   More...
Synergistic Action of Gentamicin and Bacteriophage in a Continuous Culture Population of Staphylococcus aureus  Friday, November 30, 2012   More...
2, 3, 5, 4'-Tetrahydroxystilbene-2-O-Beta-D-Glucoside Improves Gastrointestinal Motility Disorders in STZ-Induced Diabetic Mice  Monday, December 03, 2012   More...
Human Monoclonal Antibodies against Glucagon Receptor Improve Glucose Homeostasis by Suppression of Hepatic Glucose Output in Diet-Induced Obese Mice  Monday, December 03, 2012   More...
Extract of Kuding Tea Prevents High-Fat Diet-Induced Metabolic Disorders in C57BL/6 Mice via Liver X Receptor (LXR) ß Antagonism  Tuesday, December 04, 2012   More...
Development of a Novel DNA Aptamer Ligand Targeting to Primary Cultured Tumor Endothelial Cells by a Cell-Based SELEX Method  Tuesday, December 04, 2012   More...
Willingness to Participate in HIV Vaccine Trials among Men Who Have Sex with Men in Chennai and Mumbai, India: A Social Ecological Approach  Tuesday, December 04, 2012   More...
Prevention of Vaginal SHIV Transmission in Macaques by a Coitally-Dependent Truvada Regimen  Tuesday, December 04, 2012   More...
Antipsychotic-Induced Movement Disorders in Long-Stay Psychiatric Patients and 45 Tag SNPs in 7 Candidate Genes: A Prospective Study  Tuesday, December 04, 2012   More...
Cost-Effectiveness of Buprenorphine and Naltrexone Treatments for Heroin Dependence in Malaysia  Tuesday, December 04, 2012   More...
Adverse Drug Reactions Causing Admission to a Paediatric Hospital  Tuesday, December 04, 2012   More...
Local Arginase Inhibition during Early Reperfusion Mediates Cardioprotection via Increased Nitric Oxide Production  Tuesday, July 31, 2012   More...
Aciculatin Inhibits Granulocyte Colony-Stimulating Factor Production by Human Interleukin 1ß-Stimulated Fibroblast-Like Synoviocytes  Tuesday, July 31, 2012   More...
Differential Trypanocidal Activity of Novel Macrolide Antibiotics; Correlation to Genetic Lineage  Tuesday, July 31, 2012   More...
Beneficial Effects on Arterial Stiffness and Pulse-Wave Reflection of Combined Enalapril and Candesartan in Chronic Kidney Disease - A Randomized Trial  Tuesday, July 31, 2012   More...
An Induced Pocket for the Binding of Potent Fusion Inhibitor CL-385319 with H5N1 Influenza Virus Hemagglutinin  Thursday, August 02, 2012   More...
Effectiveness and Cost-Effectiveness of Antidepressants in Primary Care: A Multiple Treatment Comparison Meta-Analysis and Cost-Effectiveness Model  Thursday, August 02, 2012   More...
Solvent Free Fabrication of Micro and Nanostructured Drug Coatings by Thermal Evaporation for Controlled Release and Increased Effects  Wednesday, August 01, 2012   More...
Antitumor Activity of Emodin against Pancreatic Cancer Depends on Its Dual Role: Promotion of Apoptosis and Suppression of Angiogenesis  Thursday, August 02, 2012   More...
Long Term Stabilization of Expanding Aortic Aneurysms by a Short Course of Cyclosporine A through Transforming Growth Factor-Beta Induction  Wednesday, December 14, 2011   More...
Development and Inter-Rater Reliability of the Liverpool Adverse Drug Reaction Causality Assessment Tool  Wednesday, December 14, 2011   More...
Learning and Memory Alterations Are Associated with Hippocampal N-acetylaspartate in a Rat Model of Depression as Measured by 1H-MRS  Wednesday, December 14, 2011   More...
Inhibition of Influenza A Virus (H1N1) Fusion by Benzenesulfonamide Derivatives Targeting Viral Hemagglutinin  Thursday, December 15, 2011   More...
Statin-Associated Muscular and Renal Adverse Events: Data Mining of the Public Version of the FDA Adverse Event Reporting System  Tuesday, December 20, 2011   More...
Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer, Inhibits Amyloid-ß-Mediated Alzheimer's Disease-Associated Pathogenesis In Vitro and In Vivo  Thursday, February 23, 2012   More...
P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action  Thursday, February 23, 2012   More...
Exendin-4 Ameliorates Motor Neuron Degeneration in Cellular and Animal Models of Amyotrophic Lateral Sclerosis  Thursday, February 23, 2012   More...
Genome Wide Adaptations of Plasmodium falciparum in Response to Lumefantrine Selective Drug Pressure  Monday, February 27, 2012   More...
Serotonin Antagonism Improves Platelet Inhibition in Clopidogrel Low-Responders after Coronary Stent Placement: An In Vitro Pilot Study  Monday, February 27, 2012   More...
Development and Validation of an Automated High-Throughput System for Zebrafish In Vivo Screenings  Tuesday, May 15, 2012   More...
Examining the Interactome of Huperzine A by Magnetic Biopanning  Wednesday, May 16, 2012   More...
Influence of Neonatal Hypothyroidism on Hepatic Gene Expression and Lipid Metabolism in Adulthood  Wednesday, May 16, 2012   More...
The Risk of Amenorrhea Is Related to Chemotherapy-Induced Leucopenia in Breast Cancer Patients Receiving Epirubicin and Taxane Based Chemotherapy  Wednesday, May 16, 2012   More...
Tetrahydrouridine Inhibits Cell Proliferation through Cell Cycle Regulation Regardless of Cytidine Deaminase Expression Levels  Wednesday, May 16, 2012   More...
Adherence to Interferon ß-1b Treatment in Patients with Multiple Sclerosis in Spain  Wednesday, May 16, 2012   More...
Association of Typical versus Atypical Antipsychotics with Symptoms and Quality of Life in Schizophrenia  Wednesday, May 16, 2012   More...
Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound  Friday, May 18, 2012   More...
Responses to Dehydration in the One-Humped Camel and Effects of Blocking the Renin-Angiotensin System  Friday, May 18, 2012   More...
Neuronatin in a Subset of Glioblastoma Multiforme Tumor Progenitor Cells Is Associated with Increased Cell Proliferation and Shorter Patient Survival  Friday, May 18, 2012   More...
The JNK Inhibitor XG-102 Protects against TNBS-Induced Colitis  Tuesday, March 13, 2012   More...
Dendrimers Bind Antioxidant Polyphenols and cisPlatin Drug  Tuesday, March 13, 2012   More...
Effects of Anesthetic Agents on Brain Blood Oxygenation Level Revealed with Ultra-High Field MRI  Monday, March 12, 2012   More...
Common Changes in Global Gene Expression Induced by RNA Polymerase Inhibitors in shigella flexneri  Monday, March 12, 2012   More...
Blocking Autophagy Prevents Bortezomib-Induced NF-?B Activation by Reducing I-?Ba Degradation in Lymphoma Cells  Wednesday, February 29, 2012   More...
Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model  Thursday, March 01, 2012   More...
Identification of the Neogenin-Binding Site on the Repulsive Guidance Molecule A  Thursday, March 01, 2012   More...
Effects of S-Propargyl-Cysteine (SPRC) in Caerulein-Induced Acute Pancreatitis in Mice  Thursday, March 01, 2012   More...
Is Opium a Real Risk Factor for Esophageal Cancer or Just a Methodological Artifact? Hospital and Neighborhood Controls in Case-Control Studies  Thursday, March 01, 2012   More...
Flavonoid Glycosides Isolated from Unique Legume Plant Extracts as Novel Inhibitors of Xanthine Oxidase  Friday, March 02, 2012   More...
Synthesis of a Dual Functional Anti-MDR Tumor Agent PH II-7 with Elucidations of Anti-Tumor Effects and Mechanisms  Monday, March 05, 2012   More...
Exploring DNA Topoisomerase I Ligand Space in Search of Novel Anticancer Agents  Thursday, September 22, 2011   More...
Acute Effects of Nicotine Amplify Accumbal Neural Responses during Nicotine-Taking Behavior and Nicotine-Paired Environmental Cues  Thursday, September 22, 2011   More...
Global Inhibition of Reactive Oxygen Species (ROS) Inhibits Paclitaxel-Induced Painful Peripheral Neuropathy  Monday, September 26, 2011   More...
HIV Protease Inhibitors Act as Competitive Inhibitors of the Cytoplasmic Glucose Binding Site of GLUTs with Differing Affinities for GLUT1 and GLUT4  Friday, September 23, 2011   More...
Effect of Hydrogen Peroxide and Superoxide Anions on Cytosolic Ca2+: Comparison of Endothelial Cells from Large-Sized and Small-Sized Arteries  Monday, September 26, 2011   More...
Five-Year Prognosis in an Incident Cohort of People Presenting with Acute Myocardial Infarction  Thursday, October 20, 2011   More...
Identification of Direct Target Engagement Biomarkers for Kinase-Targeted Therapeutics  Monday, October 24, 2011   More...
The Antinociceptive Effects of JWH-015 in Chronic Inflammatory Pain Are Produced by Nitric Oxide-cGMP-PKG-KATP Pathway Activation Mediated by Opioids  Friday, October 21, 2011   More...
Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37  Friday, October 21, 2011   More...
Use of Recombinant Adenovirus Vectored Consensus IFN-a to Avert Severe Arenavirus Infection  Monday, October 24, 2011   More...
A Thiopurine Drug Inhibits West Nile Virus Production in Cell Culture, but Not in Mice  Monday, October 24, 2011   More...
Inhibition of hERG Potassium Channels by Celecoxib and Its Mechanism  Monday, October 24, 2011   More...
S-diclofenac Protects against Doxorubicin-Induced Cardiomyopathy in Mice via Ameliorating Cardiac Gap Junction Remodeling  Monday, October 24, 2011   More...
Protective Effects of White Button Mushroom (Agaricus bisporus) against Hepatic Steatosis in Ovariectomized Mice as a Model of Postmenopausal Women  Tuesday, October 25, 2011   More...
Elderly Subjects Have a Delayed Antibody Response and Prolonged Viraemia following Yellow Fever Vaccination: A Prospective Controlled Cohort Study  Wednesday, December 07, 2011   More...
Prescribing Trends in Bipolar Disorder: Cohort Study in the United Kingdom THIN Primary Care Database 1995–2009  Wednesday, December 07, 2011   More...
Pleiotropic Benefit of Monomeric and Oligomeric Flavanols on Vascular Health - A Randomized Controlled Clinical Pilot Study  Thursday, December 08, 2011   More...
Dexamethasone and Long-Term Outcome of Tuberculous Meningitis in Vietnamese Adults and Adolescents  Thursday, December 08, 2011   More...
Characterization of Pellicle Inhibition in Gluconacetobacter xylinus 53582 by a Small Molecule, Pellicin, Identified by a Chemical Genetics Screen  Friday, December 09, 2011   More...
Surveillance of Broad-Spectrum Antibiotic Prescription in Singaporean Hospitals: A 5-Year Longitudinal Study  Friday, December 09, 2011   More...
Structure-Based Development of Small Molecule PFKFB3 Inhibitors: A Framework for Potential Cancer Therapeutic Agents Targeting the Warburg Effect  Wednesday, September 21, 2011   More...
Incidence and Severity of Coronary Artery Disease in Patients with Atrial Fibrillation Undergoing First-Time Coronary Angiography  Wednesday, September 21, 2011   More...
Comparison of the Safety and Pharmacokinetics of ST-246® after IV Infusion or Oral Administration in Mice, Rabbits and Monkeys  Monday, August 15, 2011   More...
Dopaminergic and Serotonergic Drug Use: A Nationwide Register-Based Study of Over 1 300 000 Older People  Monday, August 15, 2011   More...
Modeling HIV/AIDS Drug Price Determinants in Brazil: Is Generic Competition a Myth?  Monday, August 15, 2011   More...
Role of Novelty Seeking Personality Traits as Mediator of the Association between COMT and Onset Age of Drug Use in Chinese Heroin Dependent Patients  Wednesday, August 17, 2011   More...
Permeation through the Cell Membrane of a Boron-Based ß-Lactamase Inhibitor  Wednesday, August 17, 2011   More...
Targeting of T/Tn Antigens with a Plant Lectin to Kill Human Leukemia Cells by Photochemotherapy  Wednesday, August 17, 2011   More...
Probing the Interaction of the Diarylquinoline TMC207 with Its Target Mycobacterial ATP Synthase  Wednesday, August 17, 2011   More...
Fluorescence Dequenching Makes Haem-Free Soluble Guanylate Cyclase Detectable in Living Cells  Wednesday, August 17, 2011   More...
Real Time Enzyme Inhibition Assays Provide Insights into Differences in Binding of Neuraminidase Inhibitors to Wild Type and Mutant Influenza Viruses  Wednesday, August 17, 2011   More...
Bothrops jararaca Peptide with Anti-Hypertensive Action Normalizes Endothelium Dysfunction Involved in Physiopathology of Preeclampsia  Wednesday, August 17, 2011   More...
Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome  Wednesday, August 17, 2011   More...
Adherence of Pharmaceutical Advertisements in Medical Journals to FDA Guidelines and Content for Safe Prescribing  Wednesday, August 17, 2011   More...
Autoluminescent Mycobacterium tuberculosis for Rapid, Real-Time, Non-Invasive Assessment of Drug and Vaccine Efficacy  Wednesday, January 11, 2012   More...
Mitochondrial Electron Transport Is the Cellular Target of the Oncology Drug Elesclomol  Wednesday, January 11, 2012   More...
The Protein Kinase C Inhibitor Enzastaurin Exhibits Antitumor Activity against Uveal Melanoma  Thursday, January 12, 2012   More...
Granulocyte-Colony Stimulating Factor (G-CSF) Improves Motor Recovery in the Rat Impactor Model for Spinal Cord Injury  Thursday, January 12, 2012   More...
GABAergic Gene Expression in Postmortem Hippocampus from Alcoholics and Cocaine Addicts; Corresponding Findings in Alcohol-Naïve P and NP Rats  Friday, January 13, 2012   More...
Intestinal Absorption and First-Pass Metabolism of Polyphenol Compounds in Rat and Their Transport Dynamics in Caco-2 Cells  Friday, January 13, 2012   More...
Modularity in Protein Complex and Drug Interactions Reveals New Polypharmacological Properties  Wednesday, January 18, 2012   More...
Novel Bacterial Metabolite Merochlorin A Demonstrates in vitro Activity against Multi-Drug Resistant Methicillin-Resistant Staphylococcus aureus  Wednesday, January 18, 2012   More...
Wogonin Improves Histological and Functional Outcomes, and Reduces Activation of TLR4/NF-?B Signaling after Experimental Traumatic Brain Injury  Tuesday, January 17, 2012   More...
Bone Mineral Density in HIV-Negative Men Participating in a Tenofovir Pre-Exposure Prophylaxis Randomized Clinical Trial in San Francisco  Monday, August 29, 2011   More...
Evaluation of Two Models for Human Topoisomerase I Interaction with dsDNA and Camptothecin Derivatives  Tuesday, August 30, 2011   More...
Direct Semi-Synthesis of the Anticancer Lead-Drug Protoapigenone from Apigenin, and Synthesis of Further New Cytotoxic Protoflavone Derivatives  Tuesday, August 30, 2011   More...
Allopregnanolone Promotes Regeneration and Reduces ß-Amyloid Burden in a Preclinical Model of Alzheimer's Disease  Tuesday, August 30, 2011   More...
Studies on the Antibacterial Effects of Statins - In Vitro and In Vivo  Tuesday, August 30, 2011   More...
Metformin Treatment Has No Beneficial Effect in a Dose-Response Survival Study in the SOD1G93A Mouse Model of ALS and Is Harmful in Female Mice  Thursday, September 01, 2011   More...
High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model  Wednesday, August 31, 2011   More...
Identification of Novel Functional Inhibitors of Acid Sphingomyelinase  Wednesday, August 31, 2011   More...
Dietary a-Eleostearic Acid Ameliorates Experimental Inflammatory Bowel Disease in Mice by Activating Peroxisome Proliferator-Activated Receptor-?  Wednesday, August 31, 2011   More...
An Artemisinin-Derived Dimer Has Highly Potent Anti-Cytomegalovirus (CMV) and Anti-Cancer Activities  Wednesday, August 31, 2011   More...
Stressing the Ubiquitin-Proteasome System without 20S Proteolytic Inhibition Selectively Kills Cervical Cancer Cells  Wednesday, August 31, 2011   More...
The K+ Channel Opener 1-EBIO Potentiates Residual Function of Mutant CFTR in Rectal Biopsies from Cystic Fibrosis Patients  Wednesday, August 31, 2011   More...
Characterization of the Psychological, Physiological and EEG Profile of Acute Betel Quid Intoxication in Naïve Subjects  Wednesday, August 31, 2011   More...
Serum Penicillin G Levels Are Lower Than Expected in Adults within Two Weeks of Administration of 1.2 Million Units  Tuesday, October 04, 2011   More...
Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity  Wednesday, October 05, 2011   More...
Xanthene Food Dye, as a Modulator of Alzheimer's Disease Amyloid-beta Peptide Aggregation and the Associated Impaired Neuronal Cell Function  Wednesday, October 05, 2011   More...
New Insight into the Molecular Mechanisms of the Biological Effects of DNA Minor Groove Binders  Wednesday, October 05, 2011   More...
Direct Translocation as Major Cellular Uptake for CADY Self-Assembling Peptide-Based Nanoparticles  Wednesday, October 05, 2011   More...
Praziquantel Facilitates IFN-?-Producing CD8+ T Cells (Tc1) and IL-17-Producing CD8+ T Cells (Tc17) Responses to DNA Vaccination in Mice  Wednesday, October 05, 2011   More...
A Novel Genotype of GB Virus C: Its Identification and Predominance among Injecting Drug Users in Yunnan, China  Thursday, October 06, 2011   More...
Peroral Amphotericin B Polymer Nanoparticles Lead to Comparable or Superior In Vivo Antifungal Activity to That of Intravenous Ambisome® or Fungizone™  Thursday, October 06, 2011   More...
Lack of Effect of Methylene Blue in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis  Thursday, October 06, 2011   More...
15-Deoxy-?12,14 Prostaglandin J2 Reduces the Formation of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice  Friday, October 07, 2011   More...
Ligand-Directed Functional Selectivity at the Mu Opioid Receptor Revealed by Label-Free Integrative Pharmacology On-Target  Friday, October 07, 2011   More...
Effect of ABCB1 and ABCC3 Polymorphisms on Osteosarcoma Survival after Chemotherapy: A Pharmacogenetic Study  Friday, October 07, 2011   More...
Liver Afferents Contribute to Water Drinking-Induced Sympathetic Activation in Human Subjects: A Clinical Trial  Friday, October 07, 2011   More...
The Role of Early Life Experience and Species Differences in Alcohol Intake in Microtine Rodents  Friday, June 22, 2012   More...
Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study  Friday, June 22, 2012   More...
Role of IKK/NF-?B Signaling in Extinction of Conditioned Place Aversion Memory in Rats  Tuesday, June 26, 2012   More...
A Phthalimide Derivative That Inhibits Centrosomal Clustering Is Effective on Multiple Myeloma  Monday, June 25, 2012   More...
Human Peripheral Blood Mononuclear Cells Exhibit Heterogeneous CD52 Expression Levels and Show Differential Sensitivity to Alemtuzumab Mediated Cytolysis  Monday, June 25, 2012   More...
Inhibition of Hippocampal Synaptic Activity by ATP, Hypoxia or Oxygen-Glucose Deprivation Does Not Require CD73  Monday, June 25, 2012   More...
Thaliporphine Preserves Cardiac Function of Endotoxemic Rabbits by Both Directly and Indirectly Attenuating NF?B Signaling Pathway  Monday, June 25, 2012   More...
Neutralization of IL-8 Prevents the Induction of Dermatologic Adverse Events Associated with the Inhibition of Epidermal Growth Factor Receptor  Monday, June 25, 2012   More...
Programmed Chemotherapy for Patients with Metastatic Unresectable Gastric Cancer  Tuesday, June 26, 2012   More...
UniDrug-Target: A Computational Tool to Identify Unique Drug Targets in Pathogenic Bacteria  Wednesday, March 14, 2012   More...
Identification of Common Biological Pathways and Drug Targets Across Multiple Respiratory Viruses Based on Human Host Gene Expression Analysis  Wednesday, March 14, 2012   More...
SAHA Decreases HDAC 2 and 4 Levels In Vivo and Improves Molecular Phenotypes in the R6/2 Mouse Model of Huntington's Disease  Monday, November 28, 2011   More...
Darinaparsin Is a Multivalent Chemotherapeutic Which Induces Incomplete Stress Response with Disruption of Microtubules and Shh Signaling  Tuesday, November 15, 2011   More...
Astragalus Polysaccharides Lowers Plasma Cholesterol through Mechanisms Distinct from Statins  Wednesday, November 16, 2011   More...
Potential Biomarkers in Mouse Myocardium of Doxorubicin-Induced Cardiomyopathy: A Metabonomic Method and Its Application  Wednesday, November 16, 2011   More...
Design, Synthesis, and Pharmacological Evaluation of Haloperidol Derivatives as Novel Potent Calcium Channel Blockers with Vasodilator Activity  Wednesday, November 16, 2011   More...
FDA-Approved Drugs that Protect Mammalian Neurons from Glucose Toxicity Slow Aging Dependent on Cbp and Protect Against Proteotoxicity  Wednesday, November 16, 2011   More...
Adolescent Oxytocin Exposure Causes Persistent Reductions in Anxiety and Alcohol Consumption and Enhances Sociability in Rats  Wednesday, November 16, 2011   More...
Clinical and Genetic Determinants of Warfarin Pharmacokinetics and Pharmacodynamics during Treatment Initiation  Wednesday, November 16, 2011   More...
Antibiotics Shaping Bacterial Genome: Deletion of an IS91 Flanked Virulence Determinant upon Exposure to Subinhibitory Antibiotic Concentrations  Friday, November 11, 2011   More...
A TNF Receptor 2 Selective Agonist Rescues Human Neurons from Oxidative Stress-Induced Cell Death  Monday, November 14, 2011   More...
The HIV-1 Vpu Viroporin Inhibitor BIT225 Does Not Affect Vpu-Mediated Tetherin Antagonism  Monday, November 14, 2011   More...
Methamphetamine Increases LPS-Mediated Expression of IL-8, TNF-a and IL-1ß in Human Macrophages through Common Signaling Pathways  Thursday, March 29, 2012   More...
Nicorandil Attenuates Monocrotaline-Induced Vascular Endothelial Damage and Pulmonary Arterial Hypertension  Friday, March 30, 2012   More...
Prion Protein Is a Key Determinant of Alcohol Sensitivity through the Modulation of N-Methyl-D-Aspartate Receptor (NMDAR) Activity  Friday, April 20, 2012   More...
Enhancing the Antibiotic Antibacterial Effect by Sub Lethal Tellurite Concentrations: Tellurite and Cefotaxime Act Synergistically in Escherichia coli  Friday, April 20, 2012   More...
Anti-HIV-1 Activity of a New Scorpion Venom Peptide Derivative Kn2-7  Thursday, April 19, 2012   More...
Enhanced Brain Disposition and Effects of ?9-Tetrahydrocannabinol in P-Glycoprotein and Breast Cancer Resistance Protein Knockout Mice  Friday, April 20, 2012   More...
DW-MRI as a Biomarker to Compare Therapeutic Outcomes in Radiotherapy Regimens Incorporating Temozolomide or Gemcitabine in Glioblastoma  Friday, April 20, 2012   More...
Lestaurtinib Inhibits Histone Phosphorylation and Androgen-Dependent Gene Expression in Prostate Cancer Cells  Friday, April 20, 2012   More...
The Effect of Rosuvastatin in a Murine Model of Influenza A Infection  Friday, April 20, 2012   More...
Influence of Various Polymorphic Variants of Cytochrome P450 Oxidoreductase (POR) on Drug Metabolic Activity of CYP3A4 and CYP2B6  Tuesday, June 12, 2012   More...
The HCV Non-Nucleoside Inhibitor Tegobuvir Utilizes a Novel Mechanism of Action to Inhibit NS5B Polymerase Function  Wednesday, June 13, 2012   More...
Results and Outcome Reporting In ClinicalTrials.gov, What Makes it Happen?  Wednesday, June 13, 2012   More...
Implementation and Conduct of Therapeutic Hypothermia for Perinatal Asphyxial Encephalopathy in the UK – Analysis of National Data  Wednesday, June 13, 2012   More...
HbA1c Measured in Stored Erythrocytes Is Positively Linearly Associated with Mortality in Individuals with Diabetes Mellitus  Wednesday, June 13, 2012   More...
Humanized Mice Recapitulate Key Features of HIV-1 Infection: A Novel Concept Using Long-Acting Anti-Retroviral Drugs for Treating HIV-1  Wednesday, June 13, 2012   More...
Changes in Bone Turnover and Bone Loss in HIV-Infected Patients Changing Treatment to Tenofovir-Emtricitabine or Abacavir-Lamivudine  Friday, June 15, 2012   More...
Low Serum Glutathione Peroxidase Activity Is Associated with Increased Cardiovascular Mortality in Individuals with Low HDLc’s  Friday, June 15, 2012   More...
A Two-Step Target Binding and Selectivity Support Vector Machines Approach for Virtual Screening of Dopamine Receptor Subtype-Selective Ligands  Friday, June 15, 2012   More...
Small Molecules with Similar Structures Exhibit Agonist, Neutral Antagonist or Inverse Agonist Activity toward Angiotensin II Type 1 Receptor  Thursday, June 14, 2012   More...
Ubiquitin-Specific Peptidase 46 (Usp46) Regulates Mouse Immobile Behavior in the Tail Suspension Test through the GABAergic System  Thursday, June 14, 2012   More...
Inhibition of Soluble Epoxide Hydrolase Attenuates High-Fat-Diet–Induced Hepatic Steatosis by Reduced Systemic Inflammatory Status in Mice  Thursday, June 14, 2012   More...
Combined Cocaine Hydrolase Gene Transfer and Anti-Cocaine Vaccine Synergistically Block Cocaine-Induced Locomotion  Friday, August 17, 2012   More...
Impacts of Brain Serotonin Deficiency following Tph2 Inactivation on Development and Raphe Neuron Serotonergic Specification  Friday, August 17, 2012   More...
Prediction of the Pharmacokinetic Parameters of Triptolide in Rats Based on Endogenous Molecules in Pre-Dose Baseline Serum  Friday, August 17, 2012   More...
A Longitudinal Trial Comparing Chloroquine as Monotherapy or in Combination with Artesunate, Azithromycin or Atovaquone-Proguanil to Treat Malaria  Friday, August 17, 2012   More...
Mitochondrial Respiration - An Important Therapeutic Target in Melanoma  Friday, August 17, 2012   More...
Glass Shape Influences Consumption Rate for Alcoholic Beverages  Friday, August 17, 2012   More...
Autotaxin-Lysophosphatidic Acid Axis Is a Novel Molecular Target for Lowering Intraocular Pressure  Monday, August 20, 2012   More...
An Efficient Computational Method for Calculating Ligand Binding Affinities  Monday, August 20, 2012   More...
Design and Synthesis of Potent N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitor as Anti-Inflammatory Compounds  Monday, August 20, 2012   More...
ING1 and 5-Azacytidine Act Synergistically to Block Breast Cancer Cell Growth  Monday, August 20, 2012   More...
Overexpression of ORCA3 and G10H in Catharanthus roseus Plants Regulated Alkaloid Biosynthesis and Metabolism Revealed by NMR-Metabolomics  Monday, August 20, 2012   More...
Prevention of Ocular Scarring Post Glaucoma Filtration Surgery Using the Inflammatory Cell and Platelet Binding Modulator Saratin in a Rabbit Model  Monday, April 30, 2012   More...
Implications of Altered Glutathione Metabolism in Aspirin-Induced Oxidative Stress and Mitochondrial Dysfunction in HepG2 Cells  Monday, April 30, 2012   More...
The Influence of Spin-Labeled Fluorene Compounds on the Assembly and Toxicity of the Aß Peptide  Monday, April 30, 2012   More...
Features of Idebenone and Related Short-Chain Quinones that Rescue ATP Levels under Conditions of Impaired Mitochondrial Complex I  Friday, April 27, 2012   More...
The Antibody Targeting the E314 Peptide of Human Kv1.3 Pore Region Serves as a Novel, Potent and Specific Channel Blocker  Friday, April 27, 2012   More...
Aliskiren Prevents the Toxic Effects of Peritoneal Dialysis Fluids during Chronic Dialysis in Rats  Friday, April 27, 2012   More...
Recombinant GPI-Anchored TIMP-1 Stimulates Growth and Migration of Peritoneal Mesothelial Cells  Friday, April 27, 2012   More...
Importance of Intracellular pH in Determining the Uptake and Efficacy of the Weakly Basic Chemotherapeutic Drug, Doxorubicin  Thursday, April 26, 2012   More...
Molecular Dynamics Simulation of the Complex PBP-2x with Drug Cefuroxime to Explore the Drug Resistance Mechanism of Streptococcus suis R61  Thursday, April 26, 2012   More...
IspE Inhibitors Identified by a Combination of In Silico and In Vitro High-Throughput Screening  Wednesday, April 25, 2012   More...
Different Effects of Farrerol on an OVA-Induced Allergic Asthma and LPS-induced Acute Lung Injury  Thursday, April 26, 2012   More...
Targeted Delivery of Chemotherapy Agents Using a Liver Cancer-Specific Aptamer  Wednesday, April 25, 2012   More...
Impact of Natalizumab on Cognitive Performances and Fatigue in Relapsing Multiple Sclerosis: A Prospective, Open-Label, Two Years Observational Study  Wednesday, April 25, 2012   More...
Protection of Rat Cardiac Myocytes by Fructose-1,6-Bisphosphate and 2,3-Butanedione  Friday, April 27, 2012   More...
Expression of ABC Efflux Transporters in Placenta from Women with Insulin-Managed Diabetes  Friday, April 27, 2012   More...
Suramin Alleviates Glomerular Injury and Inflammation in the Remnant Kidney  Friday, April 27, 2012   More...
KIOM-79 Protects AGE-Induced Retinal Pericyte Apoptosis via Inhibition of NF-kappaB Activation In Vitro and In Vivo  Monday, August 20, 2012   More...
Pre-Clinical Development of BCG.HIVACAT, an Antibiotic-Free Selection Strain, for HIV-TB Pediatric Vaccine Vectored by Lysine Auxotroph of BCG  Tuesday, August 21, 2012   More...
Probing the Binding Sites of Antibiotic Drugs Doxorubicin and N-(trifluoroacetyl) Doxorubicin with Human and Bovine Serum Albumins  Friday, August 24, 2012   More...
Screen Anti-influenza Lead Compounds That Target the PAC Subunit of H5N1 Viral RNA Polymerase  Friday, August 24, 2012   More...
Integration in Working Memory: A Magnetic Stimulation Study on the Role of Left Anterior Prefrontal Cortex  Friday, August 24, 2012   More...
Clitocine Reversal of P-Glycoprotein Associated Multi-Drug Resistance through Down-Regulation of Transcription Factor NF-?B in R-HepG2 Cell Line  Wednesday, August 22, 2012   More...
A Survey of the FDA's AERS Database Regarding Muscle and Tendon Adverse Events Linked to the Statin Drug Class  Wednesday, August 22, 2012   More...
Inappropriateness of Medication Prescriptions to Elderly Patients in the Primary Care Setting: A Systematic Review  Wednesday, August 22, 2012   More...
The Role of Dorsal Anterior Cingulate Cortex in the Regulation of Craving by Reappraisal in Smokers  Wednesday, August 22, 2012   More...
Efficacy of Oral Metronidazole with Vaginal Clindamycin or Vaginal Probiotic for Bacterial Vaginosis: Randomised Placebo-Controlled Double-Blind Trial  Tuesday, April 03, 2012   More...
The Frequency of Malaria Is Similar among Women Receiving either Lopinavir/Ritonavir or Nevirapine-based Antiretroviral Treatment  Tuesday, April 03, 2012   More...
Thrombospondin-1 Type 1 Repeats in a Model of Inflammatory Bowel Disease: Transcript Profile and Therapeutic Effects  Tuesday, April 03, 2012   More...
A Prompt to the Web: The Media and Health Information Seeking Behaviour  Tuesday, April 03, 2012   More...
The 5HT1a Receptor Agonist 8-Oh DPAT Induces Protection from Lipofuscin Accumulation and Oxidative Stress in the Retinal Pigment Epithelium  Tuesday, April 03, 2012   More...
Assessment of Chitosan-Affected Metabolic Response by Peroxisome Proliferator-Activated Receptor Bioluminescent Imaging-Guided Transcriptomic Analysis  Wednesday, April 04, 2012   More...
Differential Inflammatory Response to Inhaled Lipopolysaccharide Targeted Either to the Airways or the Alveoli in Man  Wednesday, April 04, 2012   More...
Off-Label Biologic Regimens in Psoriasis: A Systematic Review of Efficacy and Safety of Dose Escalation, Reduction, and Interrupted Biologic Therapy  Wednesday, April 11, 2012   More...
Infant Safety during and after Maternal Valacyclovir Therapy in Conjunction with Antiretroviral HIV-1 Prophylaxis in a Randomized Clinical Trial  Wednesday, April 11, 2012   More...
Effect on Adherence to Nicotine Replacement Therapy of Informing Smokers Their Dose Is Determined by Their Genotype: A Randomised Controlled Trial  Wednesday, April 11, 2012   More...
Distinct Effects of Unfractionated Heparin versus Bivalirudin on Circulating Angiogenic Peptides  Wednesday, April 11, 2012   More...
Early Treatment with Fumagillin, an Inhibitor of Methionine Aminopeptidase-2, Prevents Pulmonary Hypertension in Monocrotaline-Injured Rats  Wednesday, April 11, 2012   More...
Efficacy of Short-Term High-Dose Statin in Preventing Contrast-Induced Nephropathy: A Meta-Analysis of Seven Randomized Controlled Trials  Thursday, April 12, 2012   More...
Delayed Toxicity Associated with Soluble Anthrax Toxin Receptor Decoy-Ig Fusion Protein Treatment  Thursday, April 12, 2012   More...
Genetic Dissection of Acute Ethanol Responsive Gene Networks in Prefrontal Cortex: Functional and Mechanistic Implications  Thursday, April 12, 2012   More...
Predicting Anatomical Therapeutic Chemical (ATC) Classification of Drugs by Integrating Chemical-Chemical Interactions and Similarities  Friday, April 13, 2012   More...
Collaborative Enhancement of Antibody Binding to Distinct PECAM-1 Epitopes Modulates Endothelial Targeting  Friday, April 13, 2012   More...
Activity of Clinically Relevant Antimalarial Drugs on Plasmodium falciparum Mature Gametocytes in an ATP Bioluminescence “Transmission Blocking” Assay  Friday, April 13, 2012   More...
Angiopreventive Efficacy of Pure Flavonolignans from Milk Thistle Extract against Prostate Cancer: Targeting VEGF-VEGFR Signaling  Friday, April 13, 2012   More...
Polysaccharides from Wolfberry Prevents Corticosterone-Induced Inhibition of Sexual Behavior and Increases Neurogenesis  Monday, April 16, 2012   More...
Cardiovascular Events in Patients Received Combined Fibrate/Statin Treatment versus Statin Monotherapy: Acute Coronary Syndrome Israeli Surveys Data  Monday, April 16, 2012   More...
Regulation of Chemokine and Chemokine Receptor Expression by PPAR? in Adipocytes and Macrophages  Tuesday, April 17, 2012   More...
Pilot Scale Production of Highly Efficacious and Stable Enterovirus 71 Vaccine Candidates  Tuesday, April 17, 2012   More...
Designing and Analyzing Clinical Trials with Composite Outcomes: Consideration of Possible Treatment Differences between the Individual Outcomes  Tuesday, April 17, 2012   More...
Stereoselective Regulations of P-Glycoprotein by Ginsenoside Rh2 Epimers and the Potential Mechanisms From the View of Pharmacokinetics  Wednesday, April 18, 2012   More...
Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy  Wednesday, April 18, 2012   More...
Biodegradable Thermosensitive Hydrogel for SAHA and DDP Delivery: Therapeutic Effects on Oral Squamous Cell Carcinoma Xenografts  Wednesday, April 18, 2012   More...
Human Occupancy as a Source of Indoor Airborne Bacteria  Wednesday, April 18, 2012   More...
Propylthiouracil Is Teratogenic in Murine Embryos  Wednesday, April 18, 2012   More...
GRP78 Knockdown Enhances Apoptosis via the Down-Regulation of Oxidative Stress and Akt Pathway after Epirubicin Treatment in Colon Cancer DLD-1 Cells  Wednesday, April 18, 2012   More...
Role of Serine Racemase in Behavioral Sensitization in Mice after Repeated Administration of Methamphetamine  Wednesday, April 18, 2012   More...
Male-Dominant Activation of Rat Renal Organic Anion Transporter 1 (Oat1) and 3 (Oat3) Expression by Transcription Factor BCL6  Wednesday, April 18, 2012   More...
JKA97, a Novel Benzylidene Analog of Harmine, Exerts Anti-Cancer Effects by Inducing G1 Arrest, Apoptosis, and p53-Independent Up-Regulation of p21  Friday, April 27, 2012   More...
Securin Enhances the Anti-Cancer Effects of 6-Methoxy-3-(3',4',5'-Trimethoxy-Benzoyl)-1H-Indole (BPR0L075) in Human Colorectal Cancer Cells  Thursday, April 26, 2012   More...
Effects of PPARs Agonists on Cardiac Metabolism in Littermate and Cardiomyocyte-Specific PPAR-? –Knockout (CM-PGKO) Mice  Thursday, April 26, 2012   More...
The Carbon Monoxide Releasing Molecule CORM-2 Attenuates Pseudomonas aeruginosa Biofilm Formation  Thursday, April 26, 2012   More...
Differential Scanning Fluorometry Signatures as Indicators of Enzyme Inhibitor Mode of Action: Case Study of Glutathione S-Transferase  Monday, April 30, 2012   More...
Dysfunction in Fatty Acid Amide Hydrolase Is Associated with Depressive-Like Behavior in Wistar Kyoto Rats  Monday, May 14, 2012   More...
Skin-Targeted Inhibition of PPAR ß/d by Selective Antagonists to Treat PPAR ß/d – Mediated Psoriasis-Like Skin Disease In Vivo  Monday, May 14, 2012   More...
The Tyrphostin Agent AG490 Prevents and Reverses Type 1 Diabetes in NOD Mice  Monday, May 14, 2012   More...
Inhibition Mechanism and Model of an Angiotensin I-Converting Enzyme (ACE)-Inhibitory Hexapeptide from Yeast (Saccharomyces cerevisiae)  Monday, May 14, 2012   More...
Reward-Related Dorsal Striatal Activity Differences between Former and Current Cocaine Dependent Individuals during an Interactive Competitive Game  Monday, May 14, 2012   More...
Profiles of Multidrug Resistance Protein-1 in the Peripheral Blood Mononuclear Cells of Patients with Refractory Epilepsy  Monday, May 14, 2012   More...
Small-Molecule Synthetic Compound Norcantharidin Reverses Multi-Drug Resistance by Regulating Sonic Hedgehog Signaling in Human Breast Cancer Cells  Tuesday, May 15, 2012   More...
Herbal Medicines for Parkinson's Disease: A Systematic Review of Randomized Controlled Trials  Tuesday, May 15, 2012   More...
Riboflavin Ameliorates Cisplatin Induced Toxicities under Photoillumination  Wednesday, May 02, 2012   More...
Young HIV-Infected Children and Their Adult Caregivers Prefer Tablets to Syrup Antiretroviral Medications in Africa  Wednesday, May 02, 2012   More...
The Interaction between Early Life Epilepsy and Autistic-Like Behavioral Consequences: A Role for the Mammalian Target of Rapamycin (mTOR) Pathway  Wednesday, May 02, 2012   More...
Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia  Thursday, May 03, 2012   More...
Inhibition of EP4 Signaling Attenuates Aortic Aneurysm Formation  Thursday, May 03, 2012   More...
Heart Rate and Use of Beta-Blockers in Stable Outpatients with Coronary Artery Disease  Thursday, May 03, 2012   More...
Meta-Analysis on the Effects of Octreotide on Tumor Mass in Acromegaly  Friday, May 04, 2012   More...
A Novel Solid-Phase Site-Specific PEGylation Enhances the In Vitro and In Vivo Biostabilty of Recombinant Human Keratinocyte Growth Factor 1  Friday, May 04, 2012   More...
High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery  Friday, May 04, 2012   More...
Molecular Dynamics Simulation Study and Hybrid Pharmacophore Model Development in Human LTA4H Inhibitor Design  Thursday, April 05, 2012   More...
Analysis of Polymorphisms and Haplotype Structure of the Human Thymidylate Synthase Genetic Region: A Tool for Pharmacogenetic Studies  Thursday, April 05, 2012   More...
Effect of a Dipeptidyl Peptidase-IV Inhibitor, Des-Fluoro-Sitagliptin, on Neointimal Formation after Balloon Injury in Rats  Friday, April 06, 2012   More...
Apilimod Inhibits the Production of IL-12 and IL-23 and Reduces Dendritic Cell Infiltration in Psoriasis  Friday, April 06, 2012   More...
Diammonium Glycyrrhizinate Upregulates PGC-1a and Protects against Aß1–42-Induced Neurotoxicity  Monday, April 23, 2012   More...
The EYA Tyrosine Phosphatase Activity Is Pro-Angiogenic and Is Inhibited by Benzbromarone  Tuesday, April 24, 2012   More...
Novel Small-Molecule Inhibitors of Hepatitis C Virus Entry Block Viral Spread and Promote Viral Clearance in Cell Culture  Tuesday, April 24, 2012   More...
Antagonist Effect of Triptolide on AKT Activation by Truncated Retinoid X Receptor-alpha  Tuesday, April 24, 2012   More...
A 6 Week Randomized Double-Blind Placebo-Controlled Trial of Ziprasidone for the Acute Depressive Mixed State  Tuesday, April 24, 2012   More...
Antimalarial Iron Chelator, FBS0701, Shows Asexual and Gametocyte Plasmodium falciparum Activity and Single Oral Dose Cure in a Murine Malaria Model  Monday, May 21, 2012   More...
Increase of Carbapenem-Resistant Acinetobacter baumannii Infection in Acute Care Hospitals in Taiwan: Association with Hospital Antimicrobial Usage  Monday, May 21, 2012   More...
Induction of Selective Blood-Tumor Barrier Permeability and Macromolecular Transport by a Biostable Kinin B1 Receptor Agonist in a Glioma Rat Model  Monday, May 21, 2012   More...
Procyanidin B3 Prevents Articular Cartilage Degeneration and Heterotopic Cartilage Formation in a Mouse Surgical Osteoarthritis Model  Tuesday, May 22, 2012   More...
Deep Brain Stimulation of Nucleus Accumbens Region in Alcoholism Affects Reward Processing  Tuesday, May 22, 2012   More...
Methadone-Mediated Autonomic Functioning of Male Patients with Heroin Dependence: The Influence of Borderline Personality Pattern  Tuesday, May 22, 2012   More...
Amygdala 14-3-3? as a Novel Modulator of Escalating Alcohol Intake in Mice  Tuesday, May 22, 2012   More...
Therapeutic Dosing of Acenocoumarol: Proposal of a Population Specific Pharmacogenetic Dosing Algorithm and Its Validation in North Indians  Tuesday, May 22, 2012   More...
The dUTPase Enzyme Is Essential in Mycobacterium smegmatis  Thursday, May 24, 2012   More...
Identification of Sare0718 As an Alanine-Activating Adenylation Domain in Marine Actinomycete Salinispora arenicola CNS-205  Thursday, May 24, 2012   More...
High-Throughput Top-Down Fabrication of Uniform Magnetic Particles  Thursday, May 31, 2012   More...
Retention on Buprenorphine Is Associated with High Levels of Maximal Viral Suppression among HIV-Infected Opioid Dependent Released Prisoners  Thursday, May 31, 2012   More...
Priority Medicines for Maternal and Child Health: A Global Survey of National Essential Medicines Lists  Thursday, May 31, 2012   More...
Tanshinone IIA Attenuates the Inflammatory Response and Apoptosis after Traumatic Injury of the Spinal Cord in Adult Rats  Friday, June 01, 2012   More...
Growth Inhibition and Apoptosis Induced by Osthole, A Natural Coumarin, in Hepatocellular Carcinoma  Friday, May 25, 2012   More...
Inhibition of Neuroblastoma Tumor Growth by Targeted Delivery of MicroRNA-34a Using Anti-Disialoganglioside GD2 Coated Nanoparticles  Friday, May 25, 2012   More...
Optimising Strategies for Plasmodium falciparum Malaria Elimination in Cambodia: Primaquine, Mass Drug Administration and Artemisinin Resistance  Friday, May 25, 2012   More...
Topical Insulin Accelerates Wound Healing in Diabetes by Enhancing the AKT and ERK Pathways: A Double-Blind Placebo-Controlled Clinical Trial  Friday, May 25, 2012   More...
Inhibition of Intestinal Bile Acid Transporter Slc10a2 Improves Triglyceride Metabolism and Normalizes Elevated Plasma Glucose Levels in Mice  Friday, May 25, 2012   More...
Indomethacin Reduces Glomerular and Tubular Damage Markers but Not Renal Inflammation in Chronic Kidney Disease Patients: A Post-Hoc Analysis  Friday, May 25, 2012   More...
Biophysical Assessment of Single Cell Cytotoxicity: Diesel Exhaust Particle-Treated Human Aortic Endothelial Cells  Friday, May 25, 2012   More...
p53 Modulation as a Therapeutic Strategy in Gastrointestinal Stromal Tumors  Friday, May 25, 2012   More...
Curcumin Blocks Small Cell Lung Cancer Cells Migration, Invasion, Angiogenesis, Cell Cycle and Neoplasia through Janus Kinase-STAT3 Signalling Pathway  Friday, May 25, 2012   More...
Globalization and Loss of Plant Knowledge: Challenging the Paradigm  Friday, May 25, 2012   More...
Synthesis and Biological Evaluation of Phenanthrenes as Cytotoxic Agents with Pharmacophore Modeling and ChemGPS-NP Prediction as Topo II Inhibitors  Tuesday, May 29, 2012   More...
Cloning and Functional Studies of a Splice Variant of CYP26B1 Expressed in Vascular Cells  Tuesday, May 29, 2012   More...
Cytoplasmic Fungal Lipases Release Fungicides from Ultra-Deformable Vesicular Drug Carriers  Tuesday, May 29, 2012   More...
Rifampicin for Continuation Phase Tuberculosis Treatment in Uganda: A Cost-Effectiveness Analysis  Monday, June 18, 2012   More...
Echocardiographic Evidence for Valvular Toxicity of Benfluorex: A Double-Blind Randomised Trial in Patients with Type 2 Diabetes Mellitus  Tuesday, June 19, 2012   More...
Multiorgan Metastasis of Human HER-2+ Breast Cancer in Rag2-/-;Il2rg-/- Mice and Treatment with PI3K Inhibitor  Thursday, June 21, 2012   More...
A Potent Lead Induces Apoptosis in Pancreatic Cancer Cells  Wednesday, June 20, 2012   More...
Combined Blockade of ADP Receptors and PI3-Kinase p110ß Fully Prevents Platelet and Leukocyte Activation during Hypothermic Extracorporeal Circulation  Wednesday, June 06, 2012   More...
Psychoactive Pharmaceuticals Induce Fish Gene Expression Profiles Associated with Human Idiopathic Autism  Wednesday, June 06, 2012   More...
CD6 and Syntaxin Binding Protein 6 Variants and Response to Tumor Necrosis Factor Alpha Inhibitors in Danish Patients with Rheumatoid Arthritis  Thursday, June 07, 2012   More...
Bayesian Cohort and Cross-Sectional Analyses of the PINCER Trial: A Pharmacist-Led Intervention to Reduce Medication Errors in Primary Care  Thursday, June 07, 2012   More...
Clustering by Plasma Lipoprotein Profile Reveals Two Distinct Subgroups with Positive Lipid Response to Fenofibrate Therapy  Tuesday, June 12, 2012   More...
A Randomized, Double Blind, Placebo-Controlled Trial of Pioglitazone in Combination with Riluzole in Amyotrophic Lateral Sclerosis  Friday, June 08, 2012   More...
l-Tetrahydropalmatine, an Active Component of Corydalis yanhusuo W.T. Wang, Protects against Myocardial Ischaemia-Reperfusion Injury in Rats  Friday, June 08, 2012   More...
Synergistic Anti-Tumor Effects of Combination of Photodynamic Therapy and Arsenic Compound in Cervical Cancer Cells: In Vivo and In Vitro Studies  Friday, June 08, 2012   More...
Surveillance of Antibiotic Consumption Using the “Focus of Infection” Approach in 2 Hospitals in Ujjain, India  Friday, June 08, 2012   More...
What Does It Take to Synergistically Combine Sub-Potent Natural Products into Drug-Level Potent Combinations?  Wednesday, November 28, 2012   More...
Selection for High Oridonin Yield in the Chinese Medicinal Plant Isodon (Lamiaceae) Using a Combined Phylogenetics and Population Genetics Approach  Tuesday, November 27, 2012   More...