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Biophysics
 
The Role of CyaY in Iron Sulfur Cluster Assembly on the E. coli IscU Scaffold Protein  Wednesday, July 20, 2011   More...
Human Apolipoprotein A-I-Derived Amyloid: Its Association with Atherosclerosis  Tuesday, July 19, 2011   More...
In Silico Investigation of Conformational Motions in Superfamily 2 Helicase Proteins  Tuesday, July 19, 2011   More...
Newborn Genetic Screening for Hearing Impairment: A Preliminary Study at a Tertiary Center  Tuesday, July 19, 2011   More...
Information Dynamics in Living Systems: Prokaryotes, Eukaryotes, and Cancer  Tuesday, July 19, 2011   More...
Cytochrome c-554 from Methylosinus trichosporium OB3b; a Protein That Belongs to the Cytochrome c2 Family and Exhibits a HALS-Type EPR Signal  Monday, July 18, 2011   More...
Modeling Filamentous Cyanobacteria Reveals the Advantages of Long and Fast Trichomes for Optimizing Light Exposure  Monday, July 18, 2011   More...
Predicting the Tolerated Sequences for Proteins and Protein Interfaces Using RosettaBackrub Flexible Backbone Design  Monday, July 18, 2011   More...
Single-Molecule Fluorescence Polarization Study of Conformational Change in Archaeal Group II Chaperonin  Thursday, July 14, 2011   More...
Whispering to the Deaf: Communication by a Frog without External Vocal Sac or Tympanum in Noisy Environments  Wednesday, July 13, 2011   More...
Heparin Induces Harmless Fibril Formation in Amyloidogenic W7FW14F Apomyoglobin and Amyloid Aggregation in Wild-Type Protein In Vitro  Wednesday, July 13, 2011   More...
Developing Single-Molecule TPM Experiments for Direct Observation of Successful RecA-Mediated Strand Exchange Reaction  Tuesday, July 12, 2011   More...
Bioinformatic and Genetic Association Analysis of MicroRNA Target Sites in One-Carbon Metabolism Genes  Tuesday, July 12, 2011   More...
Calpain and PARP Activation during Photoreceptor Cell Death in P23H and S334ter Rhodopsin Mutant Rats  Tuesday, July 12, 2011   More...
Analysis of Mitochondrial 3D-Deformation in Cardiomyocytes during Active Contraction Reveals Passive Structural Anisotropy of Orthogonal Short Axes  Monday, July 11, 2011   More...
Computational Exploration of Structural Hypotheses for an Additional Sequence in a Mammalian Mitochondrial Protein  Monday, July 11, 2011   More...
A Protein Aggregation Based Test for Screening of the Agents Affecting Thermostability of Proteins  Friday, July 08, 2011   More...
Spatial Organization of Mesenchymal Stem Cells In Vitro—Results from a New Individual Cell-Based Model with Podia  Friday, July 08, 2011   More...
Structure of the Full-Length Major Pilin from Streptococcus pneumoniae: Implications for Isopeptide Bond Formation in Gram-Positive Bacterial Pili  Friday, July 08, 2011   More...
Adaptive Significance of the Formation of Multi-Species Fish Spawning Aggregations near Submerged Capes  Friday, July 08, 2011   More...
The ESR1 (6q25) Locus Is Associated with Calcaneal Ultrasound Parameters and Radial Volumetric Bone Mineral Density in European Men  Thursday, July 07, 2011   More...
TBP Binding-Induced Folding of the Glucocorticoid Receptor AF1 Domain Facilitates Its Interaction with Steroid Receptor Coactivator-1  Thursday, July 07, 2011   More...
Frog Oocytes to Unveil the Structure and Supramolecular Organization of Human Transport Proteins  Thursday, July 07, 2011   More...
Membrane Bridging and Hemifusion by Denaturated Munc18  Wednesday, July 06, 2011   More...
Both the C-Terminal Polylysine Region and the Farnesylation of K-RasB Are Important for Its Specific Interaction with Calmodulin  Tuesday, July 05, 2011   More...
siRNA Off-Target Effects Can Be Reduced at Concentrations That Match Their Individual Potency  Tuesday, July 05, 2011   More...
RTL551 Treatment of EAE Reduces CD226 and T-bet+ CD4 T Cells in Periphery and Prevents Infiltration of T-bet+ IL-17, IFN-? Producing T Cells into CNS  Tuesday, July 05, 2011   More...
Trabecular Meshwork Gene Expression after Selective Laser Trabeculoplasty  Friday, July 01, 2011   More...
The Drosophila Gap Gene Network Is Composed of Two Parallel Toggle Switches  Friday, July 01, 2011   More...
Mucoadhesive Nanoparticles May Disrupt the Protective Human Mucus Barrier by Altering Its Microstructure  Wednesday, June 29, 2011   More...
Fitting the Elementary Rate Constants of the P-gp Transporter Network in the hMDR1-MDCK Confluent Cell Monolayer Using a Particle Swarm Algorithm  Tuesday, October 18, 2011   More...
The Solution Structure of the N-Terminal Domain of Human Tubulin Binding Cofactor C Reveals a Platform for Tubulin Interaction  Tuesday, October 18, 2011   More...
Pigment Epithelium-Derived Factor (PEDF) Interacts with Transportin SR2, and Active Nuclear Import Is Facilitated by a Novel Nuclear Localization Motif  Tuesday, October 18, 2011   More...
Broad-Spectrum Antiviral Activity of RNA Interference against Four Genotypes of Japanese Encephalitis Virus Based on Single MicroRNA Polycistrons  Tuesday, October 18, 2011   More...
Excision Repair Cross-Complementation Group 1 (ERCC1) Status and Lung Cancer Outcomes: A Meta-Analysis of Published Studies and Recommendations  Friday, October 14, 2011   More...
Regulation of DNA Repair Mechanism in Human Glioma Xenograft Cells both In Vitro and In Vivo in Nude Mice  Friday, October 14, 2011   More...
Identification of Intracellular and Plasma Membrane Calcium Channel Homologues in Pathogenic Parasites  Friday, October 14, 2011   More...
The Mammalian Disaggregase Machinery: Hsp110 Synergizes with Hsp70 and Hsp40 to Catalyze Protein Disaggregation and Reactivation in a Cell-Free System  Friday, October 14, 2011   More...
Isothermal Titration Calorimetric Studies on the Interaction of the Major Bovine Seminal Plasma Protein, PDC-109 with Phospholipid Membranes  Friday, October 14, 2011   More...
Robust and Task-Independent Spatial Profile of the Visual Word Form Activation in Fusiform Cortex  Friday, October 14, 2011   More...
Targeted Gene-Silencing Reveals the Functional Significance of Myocardin Signaling in the Failing Heart  Tuesday, October 18, 2011   More...
Probing the Functional Mechanism of Escherichia coli GroEL Using Circular Permutation  Tuesday, October 18, 2011   More...
Effect of Oxidative Stress on Homer Scaffolding Proteins  Monday, October 17, 2011   More...
Minimal Functional Sites Allow a Classification of Zinc Sites in Proteins  Monday, October 17, 2011   More...
A New Powerful Method for Site-Specific Transgene Stabilization Based on Chromosomal Double-Strand Break Repair  Monday, October 17, 2011   More...
A New Concept to Reveal Protein Dynamics Based on Energy Dissipation  Monday, October 17, 2011   More...
A New Euler's Formula for DNA Polyhedra  Monday, October 17, 2011   More...
Microtubule Dynamics Regulate Cyclic Stretch-Induced Cell Alignment in Human Airway Smooth Muscle Cells  Monday, October 17, 2011   More...
Effect of DNA Groove Binder Distamycin A upon Chromatin Structure  Wednesday, October 26, 2011   More...
miRConnect: Identifying Effector Genes of miRNAs and miRNA Families in Cancer Cells  Wednesday, October 26, 2011   More...
DNA Electrophoretic Migration Patterns Change after Exposure of Jurkat Cells to a Single Intense Nanosecond Electric Pulse  Friday, December 02, 2011   More...
MAP4 Mechanism that Stabilizes Mitochondrial Permeability Transition in Hypoxia: Microtubule Enhancement and DYNLT1 Interaction with VDAC1  Friday, December 02, 2011   More...
Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells  Friday, December 02, 2011   More...
Structural Studies of ß-Carbonic Anhydrase from the Green Alga Coccomyxa: Inhibitor Complexes with Anions and Acetazolamide  Monday, December 05, 2011   More...
AcrB Trimer Stability and Efflux Activity, Insight from Mutagenesis Studies  Monday, December 05, 2011   More...
Structural Position Correlation Analysis (SPCA) for Protein Family  Monday, December 05, 2011   More...
Structural Constraints on the Covariance Matrix Derived from Multiple Aligned Protein Sequences  Monday, December 05, 2011   More...
Structure of the Bro1 Domain Protein BROX and Functional Analyses of the ALIX Bro1 Domain in HIV-1 Budding  Monday, December 05, 2011   More...
Investigations on the Usefulness of CEACAMs as Potential Imaging Targets for Molecular Imaging Purposes  Monday, December 05, 2011   More...
SUMO-SIM Interactions Regulate the Activity of RGSZ2 Proteins  Tuesday, December 06, 2011   More...
A Probabilistic Fragment-Based Protein Structure Prediction Algorithm  Thursday, July 19, 2012   More...
Cofactor Binding Protects Flavodoxin against Oxidative Stress  Thursday, July 19, 2012   More...
Reevaluation of ANS Binding to Human and Bovine Serum Albumins: Key Role of Equilibrium Microdialysis in Ligand – Receptor Binding Characterization  Thursday, July 19, 2012   More...
A Role for PP1/NIPP1 in Steering Migration of Human Cancer Cells  Monday, July 16, 2012   More...
From Single Molecule Fluctuations to Muscle Contraction: A Brownian Model of A.F. Huxley's Hypotheses  Monday, July 16, 2012   More...
Cranial Irradiation Alters Dendritic Spine Density and Morphology in the Hippocampus  Monday, July 16, 2012   More...
Simulating Molecular Mechanisms of the MDM2-Mediated Regulatory Interactions: A Conformational Selection Model of the MDM2 Lid Dynamics  Monday, July 16, 2012   More...
Identification of Potential Small Molecule Binding Pockets on Rho Family GTPases  Monday, July 16, 2012   More...
Characterization of Influenza Hemagglutinin Interactions with Receptor by NMR  Monday, July 16, 2012   More...
Ultramarine, a Chromoprotein Acceptor for Förster Resonance Energy Transfer  Monday, July 16, 2012   More...
Insertion of Short Amino-Functionalized Single-Walled Carbon Nanotubes into Phospholipid Bilayer Occurs by Passive Diffusion  Monday, July 16, 2012   More...
VAPC, an Human Endogenous Inhibitor for Hepatitis C Virus (HCV) Infection, Is Intrinsically Unstructured but Forms a “Fuzzy Complex” with HCV NS5B  Tuesday, July 17, 2012   More...
Sorting the Wheat from the Chaff: Identifying miRNAs in Genomic Survey Sequences of Triticum aestivum Chromosome 1AL  Tuesday, July 17, 2012   More...
Assessment of Strain-Specific PrPSc Elongation Rates Revealed a Transformation of PrPSc Properties during Protein Misfolding Cyclic Amplification  Tuesday, July 17, 2012   More...
Distribution and Radiosensitizing Effect of Cholesterol-Coupled Dbait Molecule in Rat Model of Glioblastoma  Tuesday, July 17, 2012   More...
Kinematic Analysis Quantifies Gait Abnormalities Associated with Lameness in Broiler Chickens and Identifies Evolutionary Gait Differences  Tuesday, July 17, 2012   More...
Sequence Coevolution between RNA and Protein Characterized by Mutual Information between Residue Triplets  Wednesday, January 18, 2012   More...
Trophic Position and Metabolic Rate Predict the Long-Term Decay Process of Radioactive Cesium in Fish: A Meta-Analysis  Wednesday, January 18, 2012   More...
Chemotaxis of Cell Populations through Confined Spaces at Single-Cell Resolution  Wednesday, January 18, 2012   More...
A Novel, “Double-Clamp” Binding Mode for Human Heme Oxygenase-1 Inhibition  Thursday, January 19, 2012   More...
Imaging the Impact of Chemically Inducible Proteins on Cellular Dynamics In Vivo  Thursday, January 19, 2012   More...
The N-terminus of FILIA Forms an Atypical KH Domain with a Unique Extension Involved in Interaction with RNA  Thursday, January 19, 2012   More...
Structure of S. aureus HPPK and the Discovery of a New Substrate Site Inhibitor  Thursday, January 19, 2012   More...
The Trypanosoma cruzi Virulence Factor Oligopeptidase B (OPBTc) Assembles into an Active and Stable Dimer  Thursday, January 19, 2012   More...
Production and Characterization of Antifungal Compounds Produced by Lactobacillus plantarum IMAU10014  Thursday, January 19, 2012   More...
The Influence of Therapeutic Radiation on the Patterns of Bone Marrow in Ovary-Intact and Ovariectomized Mice  Monday, August 06, 2012   More...
Markov Models of Use-Dependence and Reverse Use-Dependence during the Mouse Cardiac Action Potential  Monday, August 06, 2012   More...
MicroRNA-30b-Mediated Regulation of Catalase Expression in Human ARPE-19 Cells  Monday, August 06, 2012   More...
The “CPC Clip Motif”: A Conserved Structural Signature for Heparin-Binding Proteins  Monday, August 06, 2012   More...
Bacterial Secretion and the Role of Diffusive and Subdiffusive First Passage Processes  Monday, August 06, 2012   More...
Serotonin Potentiates Transforming Growth Factor-beta3 Induced Biomechanical Remodeling in Avian Embryonic Atrioventricular Valves  Monday, August 06, 2012   More...
Understanding the Basis of Drug Resistance of the Mutants of aß-Tubulin Dimer via Molecular Dynamics Simulations  Tuesday, August 07, 2012   More...
The Anti-Cancer IgM Monoclonal Antibody PAT-SM6 Binds with High Avidity to the Unfolded Protein Response Regulator GRP78  Wednesday, September 19, 2012   More...
Direct Observation of the Uptake of Outer Membrane Proteins by the Periplasmic Chaperone Skp  Wednesday, September 26, 2012   More...
Co-Factor Binding Confers Substrate Specificity to Xylose Reductase from Debaryomyces hansenii  Wednesday, September 26, 2012   More...
Quantification of Ligand Binding to G-Protein Coupled Receptors on Cell Membranes by Ellipsometry  Wednesday, September 26, 2012   More...
Gene-Wide Characterization of Common Quantitative Trait Loci for ABCB1 mRNA Expression in Normal Liver Tissues in the Chinese Population  Wednesday, September 26, 2012   More...
Whole-Depth Change in Bovine Zona Pellucida Biomechanics after Fertilization: How Relevant in Hindering Polyspermy?  Wednesday, September 26, 2012   More...
Evaluation of Environmental Contamination and Estimated Radiation Doses for the Return to Residents’ Homes in Kawauchi Village, Fukushima Prefecture  Wednesday, September 26, 2012   More...
Computational Mapping Identifies Localized Mechanisms for Ablation of Atrial Fibrillation  Wednesday, September 26, 2012   More...
Catapulting Tentacles in a Sticky Carnivorous Plant  Wednesday, September 26, 2012   More...
Dimerization of DOCK2 Is Essential for DOCK2-Mediated Rac Activation and Lymphocyte Migration  Wednesday, September 26, 2012   More...
?-Tubulin 2 Nucleates Microtubules and Is Downregulated in Mouse Early Embryogenesis  Tuesday, January 03, 2012   More...
Small Interfering RNA Targeted to IGF-IR Delays Tumor Growth and Induces Proinflammatory Cytokines in a Mouse Breast Cancer Model  Tuesday, January 03, 2012   More...
Resveratrol Inhibits Protein Translation in Hepatic Cells  Thursday, December 29, 2011   More...
Efficient Maximum Likelihood Estimation of Kinetic Rate Constants from Macroscopic Currents  Thursday, December 29, 2011   More...
DNA Double-Strand Breaks Induced by Cavitational Mechanical Effects of Ultrasound in Cancer Cell Lines  Tuesday, January 03, 2012   More...
A-Site Residues Move Independently from P-Site Residues in all-Atom Molecular Dynamics Simulations of the 70S Bacterial Ribosome  Tuesday, January 03, 2012   More...
Organically Modified Silica Nanoparticles Are Biocompatible and Can Be Targeted to Neurons In Vivo  Tuesday, January 03, 2012   More...
Three-Dimensional Structure of the Trypanosome Flagellum Suggests that the Paraflagellar Rod Functions as a Biomechanical Spring  Tuesday, January 03, 2012   More...
Genomic HIV RNA Induces Innate Immune Responses through RIG-I-Dependent Sensing of Secondary-Structured RNA  Tuesday, January 03, 2012   More...
Structural and Sequence Analysis of Imelysin-Like Proteins Implicated in Bacterial Iron Uptake  Monday, July 25, 2011   More...
Analysis of Micro- and Nano-Structures of the Corneal Surface of Drosophila and Its Mutants by Atomic Force Microscopy and Optical Diffraction  Thursday, July 21, 2011   More...
Structural Basis for Sequence Specific DNA Binding and Protein Dimerization of HOXA13  Monday, August 01, 2011   More...
Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites  Friday, July 22, 2011   More...
Rationally Designed Turn Promoting Mutation in the Amyloid-ß Peptide Sequence Stabilizes Oligomers in Solution  Friday, July 22, 2011   More...
Structural Alterations from Multiple Displacement Amplification of a Human Genome Revealed by Mate-Pair Sequencing  Friday, July 22, 2011   More...
Multicomponent Analysis of Junctional Movements Regulated by Myosin II Isoforms at the Epithelial Zonula Adherens  Friday, July 22, 2011   More...
Force Measurements of TCR/pMHC Recognition at T Cell Surface  Friday, July 22, 2011   More...
A Possible Role for Integrin Signaling in Diffuse Axonal Injury  Friday, July 22, 2011   More...
C-Terminal Fluorescent Labeling Impairs Functionality of DNA Mismatch Repair Proteins  Tuesday, February 14, 2012   More...
Quantification of miRNA-mRNA Interactions  Tuesday, February 14, 2012   More...
Characterization of Profilin Polymorphism in Pollen with a Focus on Multifunctionality  Tuesday, February 14, 2012   More...
MiRNA Genes Constitute New Targets for Microsatellite Instability in Colorectal Cancer  Tuesday, February 14, 2012   More...
Universality of Thermodynamic Constants Governing Biological Growth Rates  Tuesday, February 14, 2012   More...
Protein Localization with Flexible DNA or RNA  Friday, February 10, 2012   More...
A Non-Mammalian Type Opsin 5 Functions Dually in the Photoreceptive and Non-Photoreceptive Organs of Birds  Tuesday, February 14, 2012   More...
Curcumin Promotes A-beta Fibrillation and Reduces Neurotoxicity in Transgenic Drosophila  Monday, February 13, 2012   More...
Protein Docking by the Interface Structure Similarity: How Much Structure Is Needed?  Monday, February 13, 2012   More...
Fetal Radiation Exposure Induces Testicular Cancer in Genetically Susceptible Mice  Monday, February 13, 2012   More...
Tonotopically Arranged Traveling Waves in the Miniature Hearing Organ of Bushcrickets  Monday, February 13, 2012   More...
The Effect of Surface Wave Propagation on Neural Responses to Vibration in Primate Glabrous Skin  Monday, February 13, 2012   More...
Yeast Transcription Termination Factor Rtt103 Functions in DNA Damage Response  Wednesday, February 15, 2012   More...
Use of Non-Amplified RNA Samples for Microarray Analysis of Gene Expression  Wednesday, February 15, 2012   More...
Virtual Screening, Identification and In Vitro Testing of Novel Inhibitors of O-Acetyl-L-Serine Sulfhydrylase of Entamoeba histolytica  Wednesday, February 15, 2012   More...
A MAP6-Related Protein Is Present in Protozoa and Is Involved in Flagellum Motility  Wednesday, February 15, 2012   More...
Endothelium Derived Nitric Oxide Synthase Negatively Regulates the PDGF-Survivin Pathway during Flow-Dependent Vascular Remodeling  Wednesday, February 15, 2012   More...
The Effects of Terlipressin on Regional Hemodynamics and Kidney Function in Experimental Hyperdynamic Sepsis  Wednesday, February 15, 2012   More...
S. pombe Kinesins-8 Promote Both Nucleation and Catastrophe of Microtubules  Monday, February 20, 2012   More...
A Novel Protein Kinase-Like Domain in a Selenoprotein, Widespread in the Tree of Life  Thursday, February 16, 2012   More...
Actin Filament Attachments for Sustained Motility In Vitro Are Maintained by Filament Bundling  Thursday, February 16, 2012   More...
Deciphering the Preference and Predicting the Viability of Circular Permutations in Proteins  Thursday, February 16, 2012   More...
Activation of H+-ATPase of the Plasma Membrane of Saccharomyces cerevisiae by Glucose: The Role of Sphingolipid and Lateral Enzyme Mobility  Thursday, February 16, 2012   More...
Collective Motion of Cells Mediates Segregation and Pattern Formation in Co-Cultures  Thursday, February 16, 2012   More...
Fungal Melanins Differ in Planar Stacking Distances  Thursday, February 16, 2012   More...
Tetrahydrodipicolinate N-Succinyltransferase and Dihydrodipicolinate Synthase from Pseudomonas aeruginosa: Structure Analysis and Gene Deletion  Thursday, February 16, 2012   More...
Recognition of Anesthetic Barbiturates by a Protein Binding Site: A High Resolution Structural Analysis  Thursday, February 16, 2012   More...
Decidual-Secreted Factors Alter Invasive Trophoblast Membrane and Secreted Proteins Implying a Role for Decidual Cell Regulation of Placentation  Thursday, February 16, 2012   More...
ATP-Independent Cooperative Binding of Yeast Isw1a to Bare and Nucleosomal DNA  Thursday, February 16, 2012   More...
A High-Resolution Shape Fitting and Simulation Demonstrated Equatorial Cell Surface Softening during Cytokinesis and Its Promotive Role in Cytokinesis  Thursday, February 16, 2012   More...
Small Fragment Homologous Replacement: Evaluation of Factors Influencing Modification Efficiency in an Eukaryotic Assay System  Thursday, February 16, 2012   More...
A Measure of the Promiscuity of Proteins and Characteristics of Residues in the Vicinity of the Catalytic Site That Regulate Promiscuity  Thursday, February 16, 2012   More...
The Role of Actin Turnover in Retrograde Actin Network Flow in Neuronal Growth Cones  Thursday, February 16, 2012   More...
Shape and Compliance of Endothelial Cells after Shear Stress In Vitro or from Different Aortic Regions: Scanning Ion Conductance Microscopy Study  Thursday, February 16, 2012   More...
Analysis of the Native Structure, Stability and Aggregation of Biotinylated Human Lysozyme  Friday, November 16, 2012   More...
New Alternately Colored FRET Sensors for Simultaneous Monitoring of Zn2+ in Multiple Cellular Locations  Friday, November 16, 2012   More...
Modeling Huddling Penguins  Friday, November 16, 2012   More...
Position-Specific Analysis and Prediction for Protein Lysine Acetylation Based on Multiple Features  Friday, November 16, 2012   More...
Structure of the Human Discs Large 1 PDZ2– Adenomatous Polyposis Coli Cytoskeletal Polarity Complex: Insight into Peptide Engagement and PDZ Clustering  Monday, November 19, 2012   More...
Re-Introduction of Transmembrane Serine Residues Reduce the Minimum Pore Diameter of Channelrhodopsin-2  Monday, November 19, 2012   More...
Conformational Selection Underlies Recognition of a Molybdoenzyme by Its Dedicated Chaperone  Monday, November 19, 2012   More...
Insights into the Structure, Correlated Motions, and Electrostatic Properties of Two HIV-1 gp120 V3 Loops  Monday, November 19, 2012   More...
The Braid Index of Complicated DNA Polyhedral Links  Tuesday, November 20, 2012   More...
Agglutinating Activity and Structural Characterization of Scalarin, the Major Egg Protein of the Snail Pomacea scalaris (d’Orbigny, 1832)  Tuesday, November 20, 2012   More...
Structural Organization of Mammalian Prions as Probed by Limited Proteolysis  Tuesday, November 20, 2012   More...
Glutathione Depletion and Carbon Ion Radiation Potentiate Clustered DNA Lesions, Cell Death and Prevent Chromosomal Changes in Cancer Cells Progeny  Tuesday, November 20, 2012   More...
DNA Abasic Site-Selective Enhancement of Sanguinarine Fluorescence with a Large Emission Shift  Tuesday, November 20, 2012   More...
Applying Ligands Profiling Using Multiple Extended Electron Distribution Based Field Templates and Feature Trees Similarity Searching in the Discovery of New Generation of Urea-Based Antineoplastic Kinase Inhibitors  Tuesday, November 20, 2012   More...
Dysferlin-Peptides Reallocate Mutated Dysferlin Thereby Restoring Function  Tuesday, November 20, 2012   More...
Multivariate Analyses of Amyloid-Beta Oligomer Populations Indicate a Connection between Pore Formation and Cytotoxicity  Monday, October 15, 2012   More...
A Green Fluorescent Protein Containing a QFG Tri-Peptide Chromophore: Optical Properties and X-Ray Crystal Structure  Wednesday, October 10, 2012   More...
Structural Basis of the Selective Block of Kv1.2 by Maurotoxin from Computer Simulations  Wednesday, October 10, 2012   More...
Protein Array Patterning by Diffusive Gel Stamping  Wednesday, October 10, 2012   More...
The Effects of Amino Acid Composition of Glutamine-Rich Domains on Amyloid Formation and Fragmentation  Wednesday, October 10, 2012   More...
One of the Nine Doublet Microtubules of Eukaryotic Flagella Exhibits Unique and Partially Conserved Structures  Wednesday, October 10, 2012   More...
What Is the Use of Elephant Hair?  Wednesday, October 10, 2012   More...
Characterizing the Mechanism of Action of Double-Stranded RNA Activity against Western Corn Rootworm (Diabrotica virgifera virgifera LeConte)  Thursday, October 11, 2012   More...
Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities  Thursday, October 11, 2012   More...
Actin Recruitment to the Chlamydia Inclusion Is Spatiotemporally Regulated by a Mechanism That Requires Host and Bacterial Factors  Thursday, October 11, 2012   More...
Development and Function of the Voltage-Gated Sodium Current in Immature Mammalian Cochlear Inner Hair Cells  Wednesday, September 19, 2012   More...
Gene Expression and Physiological Changes of Different Populations of the Long-Lived Bivalve Arctica islandica under Low Oxygen Conditions  Wednesday, September 19, 2012   More...
Interplay between Cytoskeletal Stresses and Cell Adaptation under Chronic Flow  Wednesday, September 19, 2012   More...
Cell Visco-Elasticity Measured with AFM and Optical Trapping at Sub-Micrometer Deformations  Wednesday, September 19, 2012   More...
Effect of Solar Particle Event Radiation and Hindlimb Suspension on Gastrointestinal Tract Bacterial Translocation and Immune Activation  Wednesday, September 19, 2012   More...
GAGE Cancer-Germline Antigens Are Recruited to the Nuclear Envelope by Germ Cell-Less (GCL)  Thursday, September 20, 2012   More...
Solution Structure of MSL2 CXC Domain Reveals an Unusual Zn3Cys9 Cluster and Similarity to Pre-SET Domains of Histone Lysine Methyltransferases  Thursday, September 20, 2012   More...
Effects of Paclitaxel on EGFR Endocytic Trafficking Revealed Using Quantum Dot Tracking in Single Cells  Thursday, September 20, 2012   More...
High-Throughput 1,536-Well Fluorescence Polarization Assays for a1-Acid Glycoprotein and Human Serum Albumin Binding  Thursday, September 20, 2012   More...
Genes Encoding Cher-TPR Fusion Proteins Are Predominantly Found in Gene Clusters Encoding Chemosensory Pathways with Alternative Cellular Functions  Thursday, September 20, 2012   More...
Metastable Differentially Methylated Regions within Arabidopsis Inbred Populations Are Associated with Modified Expression of Non-Coding Transcripts  Thursday, September 20, 2012   More...
Estimating the Active Space of Male Koala Bellows: Propagation of Cues to Size and Identity in a Eucalyptus Forest  Thursday, September 20, 2012   More...
Accurate Blood Flow Measurements: Are Artificial Tracers Necessary?  Thursday, September 20, 2012   More...
Stathmin Is Dispensable for Tumor Onset in Mice  Thursday, September 20, 2012   More...
Nemaline Myopathy-Related Skeletal Muscle a-Actin (ACTA1) Mutation, Asp286Gly, Prevents Proper Strong Myosin Binding and Triggers Muscle Weakness  Thursday, September 20, 2012   More...
Quantitative Live Imaging of Endogenous DNA Replication in Mammalian Cells  Thursday, September 20, 2012   More...
Achieving High Accuracy Prediction of Minimotifs  Thursday, September 27, 2012   More...
The Interaction of Dipole Modifiers with Polyene-Sterol Complexes  Friday, September 21, 2012   More...
Functional Studies of ssDNA Binding Ability of MarR Family Protein TcaR from Staphylococcus epidermidis  Friday, September 21, 2012   More...
Characterization of Molecular Determinants of the Conformational Stability of Macrophage Migration Inhibitory Factor: Leucine 46 Hydrophobic Pocket  Friday, September 21, 2012   More...
Heterogeneous Nucleation of Protein Crystals on Fluorinated Layered Silicate  Wednesday, July 27, 2011   More...
Plasticity in Major Ampullate Silk Production in Relation to Spider Phylogeny and Ecology  Wednesday, July 27, 2011   More...
Predicting Inactive Conformations of Protein Kinases Using Active Structures: Conformational Selection of Type-II Inhibitors  Wednesday, July 27, 2011   More...
Comprehensive Phylogenetic Reconstruction of Amoebozoa Based on Concatenated Analyses of SSU-rDNA and Actin Genes  Thursday, July 28, 2011   More...
Force-Induced Unfolding Simulations of the Human Notch1 Negative Regulatory Region: Possible Roles of the Heterodimerization Domain in Mechanosensing  Thursday, July 28, 2011   More...
Highly Anomalous Energetics of Protein Cold Denaturation Linked to Folding-Unfolding Kinetics  Friday, July 29, 2011   More...
Differential Gene Expression in the Siphonophore Nanomia bijuga (Cnidaria) Assessed with Multiple Next-Generation Sequencing Workflows  Friday, July 29, 2011   More...
Modeling Disordered Regions in Proteins Using Rosetta  Friday, July 29, 2011   More...
Aß Peptide Fibrillar Architectures Controlled by Conformational Constraints of the Monomer  Thursday, September 29, 2011   More...
Gene Expression Analysis in the Thalamus and Cerebrum of Horses Experimentally Infected with West Nile Virus  Tuesday, October 04, 2011   More...
Amelogenin Supramolecular Assembly in Nanospheres Defined by a Complex Helix-Coil-PPII Helix 3D-Structure  Monday, October 03, 2011   More...
Nucleotide Discrimination with DNA Immobilized in the MspA Nanopore  Tuesday, October 04, 2011   More...
MicroRNA Profiling during Cardiomyocyte-Specific Differentiation of Murine Embryonic Stem Cells Based on Two Different miRNA Array Platforms  Monday, October 03, 2011   More...
Insights into the Membrane Interactions of the Saposin-Like Proteins Na-SLP-1 and Ac-SLP-1 from Human and Dog Hookworm  Monday, October 03, 2011   More...
Synapse Geometry and Receptor Dynamics Modulate Synaptic Strength  Monday, October 03, 2011   More...
How to Change the Oligomeric State of a Circular Protein Assembly: Switch from 11-Subunit to 12-Subunit TRAP Suggests a General Mechanism  Monday, October 03, 2011   More...
Impact of the Genome on the Epigenome Is Manifested in DNA Methylation Patterns of Imprinted Regions in Monozygotic and Dizygotic Twins  Monday, October 03, 2011   More...
Down Regulation of a Gene for Cadherin, but Not Alkaline Phosphatase, Associated with Cry1Ab Resistance in the Sugarcane Borer Diatraea saccharalis  Monday, October 03, 2011   More...
GENE-Counter: A Computational Pipeline for the Analysis of RNA-Seq Data for Gene Expression Differences  Thursday, October 06, 2011   More...
Structural and Biochemical Studies of Human 4-hydroxy-2-oxoglutarate Aldolase: Implications for Hydroxyproline Metabolism in Primary Hyperoxaluria  Thursday, October 06, 2011   More...
Elution of Labile Fluorescent Dye from Nanoparticles during Biological Use  Thursday, October 06, 2011   More...
The Energy Landscape Analysis of Cancer Mutations in Protein Kinases  Thursday, October 06, 2011   More...
Functional Complexity of the Axonal Growth Cone: A Proteomic Analysis  Monday, February 27, 2012   More...
Myelin 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation  Wednesday, February 29, 2012   More...
Out of Plane Distortions of the Heme b of Escherichia coli Succinate Dehydrogenase  Wednesday, February 29, 2012   More...
3D Morphology, Ultrastructure and Development of Ceratomyxa puntazzi Stages: First Insights into the Mechanisms of Motility and Budding in the Myxozoa  Wednesday, February 29, 2012   More...
Macro-to-Micro Structural Proteomics: Native Source Proteins for High-Throughput Crystallization  Wednesday, February 29, 2012   More...
Structural Analysis of the C-Terminal Region (Modules 18–20) of Complement Regulator Factor H (FH)  Tuesday, February 28, 2012   More...
Proteomic Profile of Reversible Protein Oxidation Using PROP, Purification of Reversibly Oxidized Proteins  Tuesday, February 28, 2012   More...
Differential, Phosphorylation Dependent Trafficking of AQP2 in LLC-PK1 Cells  Tuesday, February 28, 2012   More...
Exocyst Subunits Exo70 and Exo84 Cooperate with Small GTPases to Regulate Behavior and Endocytic Trafficking in C. elegans  Tuesday, February 28, 2012   More...
Crystal Structure of the Minimalist Max-E47 Protein Chimera  Tuesday, February 28, 2012   More...
Intra- and Inter-Subunit Disulfide Bond Formation Is Nonessential in Adeno-Associated Viral Capsids  Tuesday, February 28, 2012   More...
Structural Stability of Human Protein Tyrosine Phosphatase ? Catalytic Domain: Effect of Point Mutations  Tuesday, February 28, 2012   More...
Spatial Localisation of Actin Filaments across Developmental Stages of the Malaria Parasite  Tuesday, February 28, 2012   More...
Cellular Traction Stresses Increase with Increasing Metastatic Potential  Tuesday, February 28, 2012   More...
On Docking, Scoring and Assessing Protein-DNA Complexes in a Rigid-Body Framework  Wednesday, February 29, 2012   More...
Effect of P to A Mutation of the N-Terminal Residue Adjacent to the Rgd Motif on Rhodostomin: Importance of Dynamics in Integrin Recognition  Wednesday, January 04, 2012   More...
Disease-Associated Mutations Prevent GPR56-Collagen III Interaction  Wednesday, January 04, 2012   More...
Interaction of Proliferation Cell Nuclear Antigen (PCNA) with c-Abl in Cell Proliferation and Response to DNA Damages in Breast Cancer  Wednesday, January 04, 2012   More...
Implication for Functions of the Ectopic Adipocyte Copper Amine Oxidase (AOC3) from Purified Enzyme and Cell-Based Kinetic Studies  Wednesday, January 04, 2012   More...
Knock Down of Heat Shock Protein 27 (HspB1) Induces Degradation of Several Putative Client Proteins  Wednesday, January 04, 2012   More...
Concentration-Dependent, Size-Independent Toxicity of Citrate Capped AuNPs in Drosophila melanogaster  Wednesday, January 04, 2012   More...
SRPX2 Is a Novel Chondroitin Sulfate Proteoglycan That Is Overexpressed in Gastrointestinal Cancer  Thursday, January 05, 2012   More...
Trafficking-Deficient G572R-hERG and E637K-hERG Activate Stress and Clearance Pathways in Endoplasmic Reticulum  Thursday, January 05, 2012   More...
Deletion of the RNaseIII Enzyme Dicer in Thyroid Follicular Cells Causes Hypothyroidism with Signs of Neoplastic Alterations  Thursday, January 05, 2012   More...
Human PAPS Synthase Isoforms Are Dynamically Regulated Enzymes with Access to Nucleus and Cytoplasm  Thursday, January 05, 2012   More...
Pre-Power-Stroke Cross-Bridges Contribute to Force Transients during Imposed Shortening in Isolated Muscle Fibers  Thursday, January 05, 2012   More...
Conformational Altered p53 as an Early Marker of Oxidative Stress in Alzheimer's Disease  Thursday, January 05, 2012   More...
AHR2 Mutant Reveals Functional Diversity of Aryl Hydrocarbon Receptors in Zebrafish  Thursday, January 05, 2012   More...
Quantifying the Dynamics of Coupled Networks of Switches and Oscillators  Thursday, January 05, 2012   More...
ßB1-Crystallin: Thermodynamic Profiles of Molecular Interactions  Friday, January 06, 2012   More...
Combining Optimal Control Theory and Molecular Dynamics for Protein Folding  Friday, January 06, 2012   More...
Trihydrophobin 1 Phosphorylation by c-Src Regulates MAPK/ERK Signaling and Cell Migration  Friday, January 06, 2012   More...
IQSeq: Integrated Isoform Quantification Analysis Based on Next-Generation Sequencing  Friday, January 06, 2012   More...
Highly Dynamic Host Actin Reorganization around Developing Plasmodium Inside Hepatocytes  Friday, January 06, 2012   More...
In situ Biological Dose Mapping Estimates the Radiation Burden Delivered to ‘Spared’ Tissue between Synchrotron X-Ray Microbeam Radiotherapy Tracks  Friday, January 06, 2012   More...
Influence of Molecular Noise on the Growth of Single Cells and Bacterial Populations  Friday, January 06, 2012   More...
Modeling the Role of Negative Cooperativity in Metabolic Regulation and Homeostasis  Friday, November 09, 2012   More...
Structural Variation and Uniformity among Tetraloop-Receptor Interactions and Other Loop-Helix Interactions in RNA Crystal Structures  Friday, November 09, 2012   More...
Genetic PEGylation  Thursday, November 08, 2012   More...
Variation in the Mechanical Unfolding Pathway of p53DBD Induced by Interaction with p53 N-Terminal Region or DNA  Thursday, November 08, 2012   More...
Single Cell Analysis of Yeast Replicative Aging Using a New Generation of Microfluidic Device  Thursday, November 08, 2012   More...
Coarse-Grained Prediction of RNA Loop Structures  Thursday, November 08, 2012   More...
Structures of SHV-1 ß-Lactamase with Penem and Penam Sulfone Inhibitors That Form Cyclic Intermediates Stabilized by Carbonyl Conjugation  Thursday, November 08, 2012   More...
A Resonance Approach to Cochlear Mechanics  Thursday, November 08, 2012   More...
The Importance of Synergy between Deep Inspirations and Fluidization in Reversing Airway Closure  Thursday, November 08, 2012   More...
DNA-Interactive Properties of Crotamine, a Cell-Penetrating Polypeptide and a Potential Drug Carrier  Thursday, November 08, 2012   More...
Interaction between Soluble and Membrane-Embedded Potassium Channel Peptides Monitored by Fourier Transform Infrared Spectroscopy  Thursday, November 08, 2012   More...
Structural Organization of DNA in Chlorella Viruses  Thursday, February 16, 2012   More...
Inherent Structural Disorder and Dimerisation of Murine Norovirus NS1-2 Protein  Tuesday, February 07, 2012   More...
Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes  Tuesday, February 07, 2012   More...
The Thermal Structural Transition of Alpha-Crystallin Modulates Subunit Interactions and Increases Protein Solubility  Tuesday, February 07, 2012   More...
Composite Structural Motifs of Binding Sites for Delineating Biological Functions of Proteins  Wednesday, February 08, 2012   More...
RAMTaB: Robust Alignment of Multi-Tag Bioimages  Wednesday, February 08, 2012   More...
Mutations in Human aA-Crystallin/sHSP Affect Subunit Exchange Interaction with aB-Crystallin  Wednesday, February 08, 2012   More...
Structural and Functional Insights into Endoglin Ligand Recognition and Binding  Wednesday, February 08, 2012   More...
Unraveling the Global microRNAome Responses to Ionizing Radiation in Human Embryonic Stem Cells  Wednesday, February 08, 2012   More...
Myosin IIA Modulates T Cell Receptor Transport and CasL Phosphorylation during Early Immunological Synapse Formation  Wednesday, February 08, 2012   More...
Structure of an MmyB-Like Regulator from C. aurantiacus, Member of a New Transcription Factor Family Linked to Antibiotic Metabolism in Actinomycetes  Thursday, July 26, 2012   More...
The Crystal Structures of Dystrophin and Utrophin Spectrin Repeats: Implications for Domain Boundaries  Friday, July 20, 2012   More...
Polyglutamine Aggregate Structure In Vitro and In Vivo; New Avenues for Coherent Anti-Stokes Raman Scattering Microscopy  Friday, July 20, 2012   More...
14-3-3? is a Binding Partner of Rat Eag1 Potassium Channels  Friday, July 20, 2012   More...
Theory on the Dynamics of Feedforward Loops in the Transcription Factor Networks  Friday, July 20, 2012   More...
Hepatitis B Viral DNA Decline at Loss of HBeAg Is Mainly Explained by Reduced cccDNA Load – Down-Regulated Transcription of PgRNA Has Limited Impact  Friday, July 20, 2012   More...
BLM and RMI1 Alleviate RPA Inhibition of TopoIIIa Decatenase Activity  Friday, July 20, 2012   More...
Highly Dynamic Microtubules Improve the Effectiveness of Early Stages of Human Influenza A/NWS/33 Virus Infection in LLC-MK2 Cells  Friday, July 20, 2012   More...
A Wnt/beta-Catenin Pathway Antagonist Chibby Binds Cenexin at the Distal End of Mother Centrioles and Functions in Primary Cilia Formation  Friday, July 20, 2012   More...
The Alveolin IMC1h Is Required for Normal Ookinete and Sporozoite Motility Behaviour and Host Colonisation in Plasmodium berghei  Monday, July 23, 2012   More...
Down-Regulation of Small Rubber Particle Protein Expression Affects Integrity of Rubber Particles and Rubber Content in Taraxacum brevicorniculatum  Monday, July 23, 2012   More...
Cortical Actin Nanodynamics Determines Nitric Oxide Release in Vascular Endothelium  Monday, July 23, 2012   More...
Conformational Analysis of Clostridium difficile Toxin B and Its Implications for Substrate Recognition  Monday, July 23, 2012   More...
Biomechanics of the Chick Embryonic Heart Outflow Tract at HH18 Using 4D Optical Coherence Tomography Imaging and Computational Modeling  Monday, July 23, 2012   More...
Mg2+ in the Major Groove Modulates B-DNA Structure and Dynamics  Monday, July 23, 2012   More...
Guanidylation and Tail Effects in Cationic Antimicrobial Lipopeptoids  Monday, July 23, 2012   More...
Second-Chance Signal Transduction Explains Cooperative Flagellar Switching  Monday, July 23, 2012   More...
Insulin-Increased L-Arginine Transport Requires A2A Adenosine Receptors Activation in Human Umbilical Vein Endothelium  Monday, July 23, 2012   More...
Disruption of Murine mp29/Syf2/Ntc31 Gene Results in Embryonic Lethality with Aberrant Checkpoint Response  Tuesday, March 20, 2012   More...
Genotyping Performance between Saliva and Blood-Derived Genomic DNAs on the DMET Array: A Comparison  Tuesday, March 20, 2012   More...
A Sensitive and Quantitative Polymerase Chain Reaction-Based Cell Free In Vitro Non-Homologous End Joining Assay for Hematopoietic Stem Cells  Tuesday, March 20, 2012   More...
Control of Gastric H,K-ATPase Activity by Cations, Voltage and Intracellular pH Analyzed by Voltage Clamp Fluorometry in Xenopus Oocytes  Tuesday, March 20, 2012   More...
E-Cadherin Destabilization Accounts for the Pathogenicity of Missense Mutations in Hereditary Diffuse Gastric Cancer  Wednesday, March 21, 2012   More...
Mechanical Force Alters Morphogenetic Movements and Segmental Gene Expression Patterns during Drosophila Embryogenesis  Wednesday, March 21, 2012   More...
In Silico Investigation of Potential Src Kinase Ligands from Traditional Chinese Medicine  Wednesday, March 21, 2012   More...
How Morphological Constraints Affect Axonal Polarity in Mouse Neurons  Wednesday, March 21, 2012   More...
Integrating Intracellular Dynamics Using CompuCell3D and Bionetsolver: Applications to Multiscale Modelling of Cancer Cell Growth and Invasion  Monday, March 26, 2012   More...
Transient Protein-Protein Interaction of the SH3-Peptide Complex via Closely Located Multiple Binding Sites  Thursday, March 22, 2012   More...
MRP14 (S100A9) Protein Interacts with Alzheimer Beta-Amyloid Peptide and Induces Its Fibrillization  Thursday, March 22, 2012   More...
Multi-Level Communication of Human Retinal Pigment Epithelial Cells via Tunneling Nanotubes  Thursday, March 22, 2012   More...
An Excitable Cortex and Memory Model Successfully Predicts New Pseudopod Dynamics  Thursday, March 22, 2012   More...
Evaluation of Methods for the Extraction and Purification of DNA from the Human Microbiome  Friday, March 23, 2012   More...
Phenomenological Analysis of ATP Dependence of Motor Proteins  Friday, March 23, 2012   More...
Rational Design and Characterization of D-Phe-Pro-D-Arg-Derived Direct Thrombin Inhibitors  Friday, March 23, 2012   More...
Detection and Quantification of Citrullinated Chemokines  Friday, December 16, 2011   More...
Quantitative and Rapid DNA Detection by Laser Transmission Spectroscopy  Friday, December 16, 2011   More...
The ELBA Force Field for Coarse-Grain Modeling of Lipid Membranes  Friday, December 16, 2011   More...
Optimal Principle of Bone Structure  Friday, December 16, 2011   More...
Cyclic Stress at mHz Frequencies Aligns Fibroblasts in Direction of Zero Strain  Friday, December 16, 2011   More...
Synchrotron Radiation X-Ray Microfluorescence Reveals Polarized Distribution of Atomic Elements during Differentiation of Pluripotent Stem Cells  Friday, December 16, 2011   More...
The Nrf1 CNC-bZIP Protein Is Regulated by the Proteasome and Activated by Hypoxia  Wednesday, December 21, 2011   More...
hElp3 Directly Modulates the Expression of HSP70 Gene in HeLa Cells via HAT Activity  Wednesday, December 21, 2011   More...
A Carrier for Non-Covalent Delivery of Functional Beta-Galactosidase and Antibodies against Amyloid Plaques and IgM to the Brain  Wednesday, December 21, 2011   More...
Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA2 Inhibition  Wednesday, December 21, 2011   More...
Multi-Scale Stochastic Simulation of Diffusion-Coupled Agents and Its Application to Cell Culture Simulation  Wednesday, December 21, 2011   More...
E-Cadherin Is Transcriptionally Activated via Suppression of ZEB1 Transcriptional Repressor by Small RNA-Mediated Gene Silencing  Wednesday, December 21, 2011   More...
Multi-Cellular Logistics of Collective Cell Migration  Wednesday, December 21, 2011   More...
Mutual Information for the Detection of Crush  Wednesday, December 21, 2011   More...
Protein Kinase A Regulates Molecular Chaperone Transcription and Protein Aggregation  Thursday, December 22, 2011   More...
Long-Term Alterations of Cytokines and Growth Factors Expression in Irradiated Tissues and Relation with Histological Severity Scoring  Thursday, December 22, 2011   More...
The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of a-Synuclein  Thursday, December 22, 2011   More...
Skeletal Adaptation to Intramedullary Pressure-Induced Interstitial Fluid Flow Is Enhanced in Mice Subjected to Targeted Osteocyte Ablation  Wednesday, March 07, 2012   More...
Modeling Inhomogeneous DNA Replication Kinetics  Wednesday, March 07, 2012   More...
OneG: A Computational Tool for Predicting Cryptic Intermediates in the Unfolding Kinetics of Proteins under Native Conditions  Wednesday, March 07, 2012   More...
Amyloid-Like Fibril Formation by PolyQ Proteins: A Critical Balance between the PolyQ Length and the Constraints Imposed by the Host Protein  Friday, March 09, 2012   More...
MicroRNA Expression Is Down-Regulated and Reorganized in Prefrontal Cortex of Depressed Suicide Subjects  Friday, March 09, 2012   More...
ß-sheet Topology Prediction with High Precision and Recall for ß and Mixed a/ß Proteins  Friday, March 09, 2012   More...
Testing Human Sperm Chemotaxis: How to Detect Biased Motion in Population Assays  Thursday, March 08, 2012   More...
Fast Negative Feedback Enables Mammalian Auditory Nerve Fibers to Encode a Wide Dynamic Range of Sound Intensities  Thursday, March 08, 2012   More...
Molecular Interpretation of ACTH-ß-Endorphin Coaggregation: Relevance to Secretory Granule Biogenesis  Monday, March 05, 2012   More...
Diphenyl Urea Derivatives as Inhibitors of Transketolase: A Structure-Based Virtual Screening  Monday, March 05, 2012   More...
Caveolae, Fenestrae and Transendothelial Channels Retain PV1 on the Surface of Endothelial Cells  Monday, March 05, 2012   More...
Construction of a Baculovirus-Silkworm Multigene Expression System and Its Application on Producing Virus-Like Particles  Monday, March 05, 2012   More...
Interaction Pattern of Arg 62 in the A-Pocket of Differentially Disease-Associated HLA-B27 Subtypes Suggests Distinct TCR Binding Modes  Monday, March 05, 2012   More...
The Optimal Exponent Base for emPAI Is 6.5  Monday, March 05, 2012   More...
Differential Contribution of the Repeats to Heparin Binding of HBHA, a Major Adhesin of Mycobacterium tuberculosis  Monday, March 05, 2012   More...
Crystallization and Preliminary Analysis of Crystals of the 24-Meric Hemocyanin of the Emperor Scorpion (Pandinus imperator)  Monday, March 05, 2012   More...
Inverse Relationship between PSA and IL-8 in Prostate Cancer: An Insight into a NF-?B-Mediated Mechanism  Monday, March 05, 2012   More...
The Tempered Polymerization of Human Neuroserpin  Tuesday, March 06, 2012   More...
Kinetics of Proton Transport into Influenza Virions by the Viral M2 Channel  Tuesday, March 06, 2012   More...
Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture  Friday, January 27, 2012   More...
Plastic and Heritable Components of Phenotypic Variation in Nucella lapillus: An Assessment Using Reciprocal Transplant and Common Garden Experiments  Friday, January 27, 2012   More...
Interactive Effects of Large- and Small-Scale Sources of Feral Honey-Bees for Sunflower in the Argentine Pampas  Friday, January 27, 2012   More...
Consistent Pattern of Local Adaptation during an Experimental Heat Wave in a Pipefish-Trematode Host-Parasite System  Friday, January 27, 2012   More...
Synergistic TLR2/6 and TLR9 Activation Protects Mice against Lethal Influenza Pneumonia  Friday, January 27, 2012   More...
Induction of Heterosubtypic Cross-Protection against Influenza by a Whole Inactivated Virus Vaccine: The Role of Viral Membrane Fusion Activity  Friday, January 27, 2012   More...
Immunohistochemical Profile for Unknown Primary Adenocarcinoma  Friday, January 27, 2012   More...
Antibody to P. falciparum in Pregnancy Varies with Intermittent Preventive Treatment Regime and Bed Net Use  Friday, January 27, 2012   More...
Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models  Friday, January 27, 2012   More...
Interventions to Influence Consulting and Antibiotic Use for Acute Respiratory Tract Infections in Children: A Systematic Review and Meta-Analysis  Friday, January 27, 2012   More...
A Piezoelectric Immunosensor Using Hybrid Self-Assembled Monolayers for Detection of Schistosoma japonicum  Friday, January 27, 2012   More...
Patient's Origin and Lifestyle Associated with CTX-M-Producing Escherichia coli: A Case-Control-Control Study  Friday, January 27, 2012   More...
A Bovine Model of Respiratory Chlamydia psittaci Infection: Challenge Dose Titration  Friday, January 27, 2012   More...
Does a Family Meetings Intervention Prevent Depression and Anxiety in Family Caregivers of Dementia Patients? A Randomized Trial  Friday, January 27, 2012   More...
LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth  Friday, January 27, 2012   More...
MIR-99a and MIR-99b Modulate TGF-ß Induced Epithelial to Mesenchymal Plasticity in Normal Murine Mammary Gland Cells  Friday, January 27, 2012   More...
Reorganizing the Intrinsic Functional Architecture of the Human Primary Motor Cortex during Rest with Non-Invasive Cortical Stimulation  Friday, January 27, 2012   More...
The Cost of Universal Health Care in India: A Model Based Estimate  Friday, January 27, 2012   More...
Myocardial Alternative RNA Splicing and Gene Expression Profiling in Early Stage Hypoplastic Left Heart Syndrome  Friday, January 27, 2012   More...
ERK1 Regulates the Hematopoietic Stem Cell Niches  Monday, January 30, 2012   More...
Simulated Warming Differentially Affects the Growth and Competitive Ability of Centaurea maculosa Populations from Home and Introduced Ranges  Monday, January 30, 2012   More...
Seeing Emotion with Your Ears: Emotional Prosody Implicitly Guides Visual Attention to Faces  Monday, January 30, 2012   More...
CCL2 Is Associated with a Faster Rate of Cognitive Decline during Early Stages of Alzheimer's Disease  Monday, January 30, 2012   More...
Quality Control and Performance of HIV Rapid Tests in a Microbicide Clinical Trial in Rural KwaZulu-Natal  Monday, January 30, 2012   More...
Automated Workflow for Preparation of cDNA for Cap Analysis of Gene Expression on a Single Molecule Sequencer  Monday, January 30, 2012   More...
TBX21 and HLX1 Polymorphisms Influence Cytokine Secretion at Birth  Monday, January 30, 2012   More...
Metabolic Profiles and cDNA-AFLP Analysis of Salvia miltiorrhiza and Salvia castanea Diel f. tomentosa Stib  Monday, January 30, 2012   More...
An Ensemble Classifier for Eukaryotic Protein Subcellular Location Prediction Using Gene Ontology Categories and Amino Acid Hydrophobicity  Monday, January 30, 2012   More...
Catalog of MicroRNA Seed Polymorphisms in Vertebrates  Friday, January 27, 2012   More...
Access to Barrier Perches Improves Behavior Repertoire in Broilers  Friday, January 27, 2012   More...
Predicting Target DNA Sequences of DNA-Binding Proteins Based on Unbound Structures  Wednesday, February 01, 2012   More...
Environmentally Realistic Exposure to the Herbicide Atrazine Alters Some Sexually Selected Traits in Male Guppies  Wednesday, February 01, 2012   More...
Conditional Ablation of Ezh2 in Murine Hearts Reveals Its Essential Roles in Endocardial Cushion Formation, Cardiomyocyte Proliferation and Survival  Wednesday, February 01, 2012   More...
Responsiveness to 6-n-Propylthiouracil (PROP) Is Associated with Salivary Levels of Two Specific Basic Proline-Rich Proteins in Humans  Wednesday, February 01, 2012   More...
Viremic HIV Infected Individuals with High CD4 T Cells and Functional Envelope Proteins Show Anti-gp41 Antibodies with Unique Specificity and Function  Wednesday, February 01, 2012   More...
Implications of Extreme Life Span in Clonal Organisms: Millenary Clones in Meadows of the Threatened Seagrass Posidonia oceanica  Wednesday, February 01, 2012   More...
Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families  Wednesday, February 01, 2012   More...
In Silico Insights into the Symbiotic Nitrogen Fixation in Sinorhizobium meliloti via Metabolic Reconstruction  Wednesday, February 01, 2012   More...
Defining Plasmodium falciparum Treatment in South West Asia: A Randomized Trial Comparing Artesunate or Primaquine Combined with Chloroquine or SP  Tuesday, January 31, 2012   More...
Early Cell Death Detection with Digital Holographic Microscopy  Tuesday, January 31, 2012   More...
A Role for VEGFR2 Activation in Endothelial Responses Caused by Barrier Disruptive OxPAPC Concentrations  Tuesday, January 31, 2012   More...
A New Eusuchian Crocodyliform with Novel Cranial Integument and Its Significance for the Origin and Evolution of Crocodylia  Tuesday, January 31, 2012   More...
Increased Inter-Colony Fusion Rates Are Associated with Reduced COI Haplotype Diversity in an Invasive Colonial Ascidian Didemnum vexillum  Tuesday, January 31, 2012   More...
Ologs: A Categorical Framework for Knowledge Representation  Tuesday, January 31, 2012   More...
Primary Xenografts of Human Prostate Tissue as a Model to Study Angiogenesis Induced by Reactive Stroma  Tuesday, January 31, 2012   More...
Novel, Objective, Multivariate Biomarkers Composed of Plasma Amino Acid Profiles for the Diagnosis and Assessment of Inflammatory Bowel Disease  Tuesday, January 31, 2012   More...
Increased GABAA Receptor e-Subunit Expression on Ventral Respiratory Column Neurons Protects Breathing during Pregnancy  Tuesday, January 31, 2012   More...
Boolean Models of Biosurfactants Production in Pseudomonas fluorescens  Tuesday, January 31, 2012   More...
Homology Inference of Protein-Protein Interactions via Conserved Binding Sites  Tuesday, January 31, 2012   More...
The Risk of Stroke after Percutaneous Vertebroplasty for Osteoporosis: A Population-Based Cohort Study  Tuesday, January 31, 2012   More...
Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types  Wednesday, February 01, 2012   More...
Polyglutamine Repeats Are Associated to Specific Sequence Biases That Are Conserved among Eukaryotes  Wednesday, February 01, 2012   More...
Season of Sampling and Season of Birth Influence Serotonin Metabolite Levels in Human Cerebrospinal Fluid  Wednesday, February 01, 2012   More...
Eradication of Metastatic Renal Cell Carcinoma after Adenovirus-Encoded TNF-Related Apoptosis-Inducing Ligand (TRAIL)/CpG Immunotherapy  Wednesday, February 01, 2012   More...
Two-Item Sentence Comprehension by a Dog (Canis familiaris)  Wednesday, February 01, 2012   More...
Tobacco Rattle Virus Vector: A Rapid and Transient Means of Silencing Manduca sexta Genes by Plant Mediated RNA Interference  Wednesday, February 01, 2012   More...
Mitogen- and Stress-Activated Kinase 1 (MSK1) Regulates Cigarette Smoke-Induced Histone Modifications on NF-?B-dependent Genes  Wednesday, February 01, 2012   More...
Genetic Association Analysis Using Sibship Data: A Multilevel Model Approach  Wednesday, February 01, 2012   More...
Helicobacter pylori CagA Triggers Expression of the Bactericidal Lectin REG3? via Gastric STAT3 Activation  Wednesday, February 01, 2012   More...
Mimicry of Food Intake: The Dynamic Interplay between Eating Companions  Wednesday, February 01, 2012   More...
Innate Sex Differences in the Timing of Spring Migration in a Songbird  Wednesday, February 01, 2012   More...
Sleep Disorders and Demand for Medical Services: Evidence from a Population-Based Longitudinal Study  Wednesday, February 01, 2012   More...
Potent Phototoxicity of Marine Bunker Oil to Translucent Herring Embryos after Prolonged Weathering  Wednesday, February 01, 2012   More...
From Food to Offspring Down: Tissue-Specific Discrimination and Turn-Over of Stable Isotopes in Herbivorous Waterbirds and Other Avian Foraging Guilds  Wednesday, February 01, 2012   More...
Trans-Synaptic Spread of Tau Pathology In Vivo  Wednesday, February 01, 2012   More...
Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling  Wednesday, February 01, 2012   More...
NGS QC Toolkit: A Toolkit for Quality Control of Next Generation Sequencing Data  Wednesday, February 01, 2012   More...
Murine GRPR and Stathmin Control in Opposite Directions both Cued Fear Extinction and Neural Activities of the Amygdala and Prefrontal Cortex  Wednesday, February 01, 2012   More...
S-LOCUS EARLY FLOWERING 3 Is Exclusively Present in the Genomes of Short-Styled Buckwheat Plants that Exhibit Heteromorphic Self-Incompatibility  Wednesday, February 01, 2012   More...
Measuring the Impacts of Community-based Grasslands Management in Mongolia's Gobi  Wednesday, February 01, 2012   More...
Knowledge-Based Reconstruction of mRNA Transcripts with Short Sequencing Reads for Transcriptome Research  Wednesday, February 01, 2012   More...
CenSeam, an International Program on Seamounts within the Census of Marine Life: Achievements and Lessons Learned  Wednesday, February 01, 2012   More...
TANGLE: Two-Level Support Vector Regression Approach for Protein Backbone Torsion Angle Prediction from Primary Sequences  Thursday, February 02, 2012   More...
Visualization and Quantitative Analysis of Reconstituted Tight Junctions Using Localization Microscopy  Thursday, February 02, 2012   More...
A Novel YY1-miR-1 Regulatory Circuit in Skeletal Myogenesis Revealed by Genome-Wide Prediction of YY1-miRNA Network  Wednesday, February 01, 2012   More...
Kosmotropic Anions Promote Conversion of Recombinant Prion Protein into a PrPSc-Like Misfolded Form  Thursday, February 09, 2012   More...
Quantum Dots for Multiplexed Detection and Characterisation of Prostate Cancer Cells Using a Scanning Near-Field Optical Microscope  Thursday, February 09, 2012   More...
Cupricyclins, Novel Redox-Active Metallopeptides Based on Conotoxins Scaffold  Friday, February 03, 2012   More...
Hydroxyl Radical Modification of Collagen Type II Increases Its Arthritogenicity and Immunogenicity  Friday, February 03, 2012   More...
Self-Organizing Circuit Assembly through Spatiotemporally Coordinated Neuronal Migration within Geometric Constraints  Tuesday, November 22, 2011   More...
The Recognition of N-Glycans by the Lectin ArtinM Mediates Cell Death of a Human Myeloid Leukemia Cell Line  Wednesday, November 23, 2011   More...
Designer Lipid-Like Peptides: A Class of Detergents for Studying Functional Olfactory Receptors Using Commercial Cell-Free Systems  Wednesday, November 23, 2011   More...
Strategies for Metagenomic-Guided Whole-Community Proteomics of Complex Microbial Environments  Wednesday, November 23, 2011   More...
The Putative Endoglucanase PcGH61D from Phanerochaete chrysosporium Is a Metal-Dependent Oxidative Enzyme that Cleaves Cellulose  Wednesday, November 23, 2011   More...
Production of dsRNA Sequences in the Host Plant Is Not Sufficient to Initiate Gene Silencing in the Colonizing Oomycete Pathogen Phytophthora parasitica  Wednesday, November 23, 2011   More...
Structure Analysis of a New Psychrophilic Marine Protease  Wednesday, November 23, 2011   More...
Atmospheric-Pressure Plasma Jet Induces Apoptosis Involving Mitochondria via Generation of Free Radicals  Tuesday, November 29, 2011   More...
Restrictions in Cell Cycle Progression of Adult Vestibular Supporting Cells in Response to Ectopic Cyclin D1 Expression  Wednesday, November 02, 2011   More...
Serine Biosynthesis with One Carbon Catabolism and the Glycine Cleavage System Represents a Novel Pathway for ATP Generation  Wednesday, November 02, 2011   More...
Characterization of Intrinsically Disordered Prostate Associated Gene (PAGE5) at Single Residue Resolution by NMR Spectroscopy  Wednesday, November 02, 2011   More...
Adapted to Roar: Functional Morphology of Tiger and Lion Vocal Folds  Wednesday, November 02, 2011   More...
Shape-Induced Terminal Differentiation of Human Epidermal Stem Cells Requires p38 and Is Regulated by Histone Acetylation  Wednesday, November 02, 2011   More...
Extracellular Matrix Ligand and Stiffness Modulate Immature Nucleus Pulposus Cell-Cell Interactions  Monday, November 07, 2011   More...
Functional Diversification of Thylakoidal Processing Peptidases in Arabidopsis thaliana  Monday, November 07, 2011   More...
Protein Characterization of a Candidate Mechanism SNP for Crohn's Disease: The Macrophage Stimulating Protein R689C Substitution  Monday, November 07, 2011   More...
Cryosurgery with Pulsed Electric Fields  Monday, November 07, 2011   More...
Reduction Theories Elucidate the Origins of Complex Biological Rhythms Generated by Interacting Delay-Induced Oscillations  Monday, November 07, 2011   More...
Determinants of the Differential Antizyme-Binding Affinity of Ornithine Decarboxylase  Thursday, November 03, 2011   More...
Quantitative Evaluation of Scintillation Camera Imaging Characteristics of Isotopes Used in Liver Radioembolization  Thursday, November 03, 2011   More...
Oscillatory Protein Expression Dynamics Endows Stem Cells with Robust Differentiation Potential  Thursday, November 03, 2011   More...
CARD8 and NLRP1 Undergo Autoproteolytic Processing through a ZU5-Like Domain  Tuesday, November 08, 2011   More...
Designer TGFß Superfamily Ligands with Diversified Functionality  Friday, November 04, 2011   More...
Revisiting the NMR Structure of the Ultrafast Downhill Folding Protein gpW from Bacteriophage ?  Friday, November 04, 2011   More...
Integrated Epigenetics of Human Breast Cancer: Synoptic Investigation of Targeted Genes, MicroRNAs and Proteins upon Demethylation Treatment  Friday, November 04, 2011   More...
Chronic Fluid Flow Is an Environmental Modifier of Renal Epithelial Function  Friday, October 28, 2011   More...
Transcriptome of Small Regulatory RNAs in the Development of the Zoonotic Parasite Trichinella spiralis  Tuesday, November 01, 2011   More...
Development of an RNA Interference Tool, Characterization of Its Target, and an Ecological Test of Caste Differentiation in the Eusocial Wasp Polistes  Tuesday, November 01, 2011   More...
The Molecular Basis for the Broad Substrate Specificity of Human Sulfotransferase 1A1  Tuesday, November 01, 2011   More...
Biophysical Analysis of Apolipoprotein E3 Variants Linked with Development of Type III Hyperlipoproteinemia  Tuesday, November 01, 2011   More...
Structural, Stability, Dynamic and Binding Properties of the ALS-Causing T46I Mutant of the hVAPB MSP Domain as Revealed by NMR and MD Simulations  Tuesday, November 01, 2011   More...
Bayesian Analysis of High-Throughput Quantitative Measurement of Protein-DNA Interactions  Tuesday, November 01, 2011   More...
Calcium-Based Nanoparticles Accelerate Skin Wound Healing  Wednesday, November 02, 2011   More...
Stereo-Selectivity of Human Serum Albumin to Enantiomeric and Isoelectronic Pollutants Dissected by Spectroscopy, Calorimetry and Bioinformatics  Wednesday, November 02, 2011   More...
A Novel Dimer-Tetramer Transition Captured by the Crystal Structure of the HIV-1 Nef  Wednesday, November 02, 2011   More...
MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R  Wednesday, November 02, 2011   More...
New Insights in the Removal of the Hydantoins, Oxidation Product of Pyrimidines, via the Base Excision and Nucleotide Incision Repair Pathways  Monday, July 25, 2011   More...
Wdr74 Is Required for Blastocyst Formation in the Mouse  Monday, July 25, 2011   More...
The Crystal Structure of the Human Co-Chaperone P58IPK  Monday, July 25, 2011   More...
New Human Papilloma Virus E2 Transcription Factor Mimics: A Tripyrrole-Peptide Conjugate with Tight and Specific DNA-Recognition  Monday, July 25, 2011   More...
The UNC-45 Chaperone Is Critical for Establishing Myosin-Based Myofibrillar Organization and Cardiac Contractility in the Drosophila Heart Model  Monday, July 25, 2011   More...
Sequence-Dependent Fluorescence of Cyanine Dyes on Microarrays  Monday, July 25, 2011   More...
Different Factors Affecting Human ANP Amyloid Aggregation and Their Implications in Congestive Heart Failure  Tuesday, July 26, 2011   More...
Conformational Plasticity of proNGF  Tuesday, July 26, 2011   More...
Dynamic Distribution of Nuclear Coactivator 4 during Mitosis: Association with Mitotic Apparatus and Midbodies  Tuesday, July 26, 2011   More...
Lethal Mutants and Truncated Selection Together Solve a Paradox of the Origin of Life  Tuesday, July 26, 2011   More...
Quantitative Photo Activated Localization Microscopy: Unraveling the Effects of Photoblinking  Tuesday, July 26, 2011   More...
Identification of Inhibitors against Mycobacterium tuberculosis Thiamin Phosphate Synthase, an Important Target for the Development of Anti-TB Drugs  Tuesday, July 26, 2011   More...
Computational Reverse-Engineering of a Spider-Venom Derived Peptide Active Against Plasmodium falciparum SUB1  Wednesday, July 27, 2011   More...
Broad-Spectrum Antiviral Therapeutics  Wednesday, July 27, 2011   More...
Peptide Substrates for Rho-Associated Kinase 2 (Rho-Kinase 2/ROCK2)  Wednesday, July 27, 2011   More...
Redundancy and Cooperativity in the Mechanics of Compositely Crosslinked Filamentous Networks  Wednesday, May 09, 2012   More...
Proteome-Wide Analysis of Single-Nucleotide Variations in the N-Glycosylation Sequon of Human Genes  Monday, May 07, 2012   More...
? sulphate PNA (PNA S): Highly Selective DNA Binding Molecule Showing Promising Antigene Activity  Monday, May 07, 2012   More...
Insight into the Assembly Properties and Functional Organisation of the Magnetotactic Bacterial Actin-like Homolog, MamK  Monday, May 07, 2012   More...
Formation of Amyloid-Like Fibrils by Y-Box Binding Protein 1 (YB-1) Is Mediated by Its Cold Shock Domain and Modulated by Disordered Terminal Domains  Tuesday, May 08, 2012   More...
In Silico Assessment of Potential Druggable Pockets on the Surface of a1-Antitrypsin Conformers  Tuesday, May 08, 2012   More...
Identification of New Agonists and Antagonists of the Insect Odorant Receptor Co-Receptor Subunit  Tuesday, May 08, 2012   More...
Beta-Strand Interfaces of Non-Dimeric Protein Oligomers Are Characterized by Scattered Charged Residue Patterns  Monday, April 09, 2012   More...
Direct Observation of Strand Passage by DNA-Topoisomerase and Its Limited Processivity  Monday, April 09, 2012   More...
Recombinant Human Endostatin Normalizes Tumor Vasculature and Enhances Radiation Response in Xenografted Human Nasopharyngeal Carcinoma Models  Monday, April 09, 2012   More...
Pdx1 Is Post-Translationally Modified In vivo and Serine 61 Is the Principal Site of Phosphorylation  Wednesday, April 11, 2012   More...
Solubility and Permeation of Hydrogen Sulfide in Lipid Membranes  Wednesday, April 11, 2012   More...
Direct Ubiquitin Independent Recognition and Degradation of a Folded Protein by the Eukaryotic Proteasomes-Origin of Intrinsic Degradation Signals  Tuesday, April 10, 2012   More...
Changes in Plasma Membrane Surface Potential of PC12 Cells as Measured by Kelvin Probe Force Microscopy  Tuesday, April 10, 2012   More...
Microtubular Stability Affects pVHL-Mediated Regulation of HIF-1alpha via the p38/MAPK Pathway in Hypoxic Cardiomyocytes  Tuesday, April 10, 2012   More...
Lack of Evidence from Studies of Soluble Protein Fragments that Knops Blood Group Polymorphisms in Complement Receptor-Type 1 Are Driven by Malaria  Tuesday, April 10, 2012   More...
CCL5 and CCR5 Interaction Promotes Cell Motility in Human Osteosarcoma  Tuesday, April 10, 2012   More...
Gliding Motility of Babesia bovis Merozoites Visualized by Time-Lapse Video Microscopy  Tuesday, April 10, 2012   More...
Genome-Wide DNA Methylation Scan in Major Depressive Disorder  Thursday, April 12, 2012   More...
Structural and Functional Diversity of Acidic Scorpion Potassium Channel Toxins  Thursday, April 12, 2012   More...
A Genome-Wide Association Study Identifies UGT1A1 as a Regulator of Serum Cell-Free DNA in Young Adults: The Cardiovascular Risk in Young Finns Study  Thursday, April 12, 2012   More...
Expression and Subcellular Localization of Mammalian Formin Fhod3 in the Embryonic and Adult Heart  Wednesday, April 11, 2012   More...
The Transition between Stochastic and Deterministic Behavior in an Excitable Gene Circuit  Wednesday, April 11, 2012   More...
Don't Fall Off the Adaptation Cliff: When Asymmetrical Fitness Selects for Suboptimal Traits  Wednesday, April 11, 2012   More...
3D Morphometric and Posture Study of Felid Scapulae Using Statistical Shape Modelling  Wednesday, April 11, 2012   More...
Neuronal Profilin Isoforms Are Addressed by Different Signalling Pathways  Wednesday, March 28, 2012   More...
The Tandem CARDs of NOD2: Intramolecular Interactions and Recognition of RIP2  Wednesday, March 28, 2012   More...
Monitoring the Size and Lateral Dynamics of ErbB1 Enriched Membrane Domains through Live Cell Plasmon Coupling Microscopy  Wednesday, March 28, 2012   More...
Crystal Structures of the Tetratricopeptide Repeat Domains of Kinesin Light Chains: Insight into Cargo Recognition Mechanisms  Wednesday, March 28, 2012   More...
The Group Delay and Suppression Pattern of the Cochlear Microphonic Potential Recorded at the Round Window  Wednesday, March 28, 2012   More...
Finite Element Analysis of Osteosynthesis Screw Fixation in the Bone Stock: An Appropriate Method for Automatic Screw Modelling  Wednesday, March 28, 2012   More...
The Lid Domain of Caenorhabditis elegans Hsc70 Influences ATP Turnover, Cofactor Binding and Protein Folding Activity  Thursday, March 29, 2012   More...
Kinetics of Inclusion Body Formation and Its Correlation with the Characteristics of Protein Aggregates in Escherichia coli  Thursday, March 29, 2012   More...
Oxygen Levels Do Not Determine Radiation Survival of Breast Cancer Stem Cells  Thursday, March 29, 2012   More...
A Robust Co-Localisation Measurement Utilising Z-Stack Image Intensity Similarities for Biological Studies  Friday, February 17, 2012   More...
Novel Covalently Linked Insulin Dimer Engineered to Investigate the Function of Insulin Dimerization  Friday, February 17, 2012   More...
Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein  Friday, February 17, 2012   More...
Integrin ß3 Crosstalk with VEGFR Accommodating Tyrosine Phosphorylation as a Regulatory Switch  Friday, February 17, 2012   More...
Accelerated Identification of Proteins by Mass Spectrometry by Employing Covalent Pre-Gel Staining with Uniblue A  Friday, February 17, 2012   More...
Study of Local Hydrodynamic Environment in Cell-Substrate Adhesion Using Side-View µPIV Technology  Friday, February 17, 2012   More...
Phosphorylation of Voltage-Dependent Anion Channel by Serine/Threonine Kinases Governs Its Interaction with Tubulin  Thursday, October 13, 2011   More...
Tensile Properties, Collagen Content, and Crosslinks in Connective Tissues of the Immature Knee Joint  Thursday, October 13, 2011   More...
Stretching Actin Filaments within Cells Enhances their Affinity for the Myosin II Motor Domain  Thursday, October 13, 2011   More...
Subcellular Heterogeneity of Ryanodine Receptor Properties in Ventricular Myocytes with Low T-Tubule Density  Thursday, October 13, 2011   More...
Novel ATP-Independent RNA Annealing Activity of the Dengue Virus NS3 Helicase  Monday, April 30, 2012   More...
Regulation of Vascular Endothelial Cell Polarization and Migration by Hsp70/Hsp90-Organizing Protein  Monday, April 30, 2012   More...
Regulatory Snapshots: Integrative Mining of Regulatory Modules from Expression Time Series and Regulatory Networks  Tuesday, May 01, 2012   More...
Polymerized Laminin-332 Matrix Supports Rapid and Tight Adhesion of Keratinocytes, Suppressing Cell Migration  Tuesday, May 01, 2012   More...
Crystal Structure of the Cysteine Desulfurase DndA from Streptomyces lividans Which Is Involved in DNA Phosphorothioation  Thursday, May 03, 2012   More...
Optimization of Cell Morphology Measurement via Single-Molecule Tracking PALM  Thursday, May 03, 2012   More...
Gene Expression Profiles of the NCI-60 Human Tumor Cell Lines Define Molecular Interaction Networks Governing Cell Migration Processes  Thursday, May 03, 2012   More...
Human Cataract Mutations in EPHA2 SAM Domain Alter Receptor Stability and Function  Thursday, May 03, 2012   More...
Deficits in Water Maze Performance and Oxidative Stress in the Hippocampus and Striatum Induced by Extremely Low Frequency Magnetic Field Exposure  Thursday, May 03, 2012   More...
Analytic Markovian Rates for Generalized Protein Structure Evolution  Wednesday, May 23, 2012   More...
Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) ? Activators and Pan-PPAR Partial Agonists  Wednesday, May 23, 2012   More...
A Predictive Model of Intein Insertion Site for Use in the Engineering of Molecular Switches  Wednesday, May 23, 2012   More...
Interaction of Virstatin with Human Serum Albumin: Spectroscopic Analysis and Molecular Modeling  Wednesday, May 23, 2012   More...
Development of Cysteine-Free Fluorescent Proteins for the Oxidative Environment  Wednesday, May 23, 2012   More...
Macromolecular Crowding Directs Extracellular Matrix Organization and Mesenchymal Stem Cell Behavior  Wednesday, May 23, 2012   More...
Multi-Patterned Dynamics of Mitochondrial Fission and Fusion in a Living Cell  Wednesday, May 23, 2012   More...
The Beneficial Effects of Antifreeze Proteins in the Vitrification of Immature Mouse Oocytes  Wednesday, May 23, 2012   More...
Dissection of Influenza A Virus M1 Protein: pH-Dependent Oligomerization of N-Terminal Domain and Dimerization of C-Terminal Domain  Thursday, May 24, 2012   More...
Thermodynamics of Aryl-Dihydroxyphenyl-Thiadiazole Binding to Human Hsp90  Thursday, May 24, 2012   More...
Identification, Expression and Target Gene Analyses of MicroRNAs in Spodoptera litura  Friday, May 25, 2012   More...
In Silico Prediction and Analysis of Caenorhabditis EF-hand Containing Proteins  Friday, May 25, 2012   More...
A Stochastic Description of Dictyostelium Chemotaxis  Friday, May 25, 2012   More...
pKa Modulation of the Acid/Base Catalyst within GH32 and GH68: A Role in Substrate/Inhibitor Specificity?  Friday, May 25, 2012   More...
The Arg233Lys AQP0 Mutation Disturbs Aquaporin0-Calmodulin Interaction Causing Polymorphic Congenital Cataract  Friday, May 25, 2012   More...
Pan-Pathway Based Interaction Profiling of FDA-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism  Friday, May 25, 2012   More...
CCR2 Acts as Scavenger for CCL2 during Monocyte Chemotaxis  Thursday, May 17, 2012   More...
Dynamic Compression of Chondrocyte-Agarose Constructs Reveals New Candidate Mechanosensitive Genes  Thursday, May 17, 2012   More...
Detailed Structural Analysis of Lipids Directly on Tissue Specimens Using a MALDI-SpiralTOF-Reflectron TOF Mass Spectrometer  Friday, May 18, 2012   More...
Intricate Correlation between Body Posture, Personality Trait and Incidence of Body Pain: A Cross-Referential Study Report  Friday, May 18, 2012   More...
Comparing Aerodynamic Efficiency in Birds and Bats Suggests Better Flight Performance in Birds  Friday, May 18, 2012   More...
Genome Sizes and the Benford Distribution  Friday, May 18, 2012   More...
A Scalable System for Production of Functional Pancreatic Progenitors from Human Embryonic Stem Cells  Friday, May 18, 2012   More...
Global MicroRNA Expression Profiling of High-Risk ER+ Breast Cancers from Patients Receiving Adjuvant Tamoxifen Mono-Therapy: A DBCG Study  Friday, May 18, 2012   More...
Intracellular Electric Field and pH Optimize Protein Localization and Movement  Friday, May 18, 2012   More...
Cell Wall Trapping of Autocrine Peptides for Human G-Protein-Coupled Receptors on the Yeast Cell Surface  Friday, May 18, 2012   More...
Insight into the Stability of Cross-ß Amyloid Fibril from VEALYL Short Peptide with Molecular Dynamics Simulation  Thursday, May 10, 2012   More...
Triggering of the dsRNA Sensors TLR3, MDA5, and RIG-I Induces CD55 Expression in Synovial Fibroblasts  Thursday, May 10, 2012   More...
DipA, a Pore-Forming Protein in the Outer Membrane of Lyme Disease Spirochetes Exhibits Specificity for the Permeation of Dicarboxylates  Thursday, May 10, 2012   More...
Versatile Toolbox for High Throughput Biochemical and Functional Studies with Fluorescent Fusion Proteins  Friday, May 11, 2012   More...
Exploring Protein Dynamics Space: The Dynasome as the Missing Link between Protein Structure and Function  Friday, May 11, 2012   More...
Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding  Friday, May 11, 2012   More...
A Regulatory Potential of the Xist Gene Promoter in Vole M. rossiaemeridionalis  Friday, May 11, 2012   More...
How Linear Tension Converts to Curvature: Geometric Control of Bone Tissue Growth  Friday, May 11, 2012   More...
Activation Mobilizes the Cholesterol in the Late Endosomes-Lysosomes of Niemann Pick Type C Cells  Friday, January 20, 2012   More...
Anti- Japanese-Encephalitis-Viral Effects of Kaempferol and Daidzin and Their RNA-Binding Characteristics  Friday, January 20, 2012   More...
Less Can Be More: RNA-Adapters May Enhance Coding Capacity of Replicators  Monday, January 23, 2012   More...
Polar Electrophoresis: Shape of Two-Dimensional Maps Is as Important as Size  Monday, January 23, 2012   More...
Structure-Function Studies of DNA Binding Domain of Response Regulator KdpE Reveals Equal Affinity Interactions at DNA Half-Sites  Monday, January 23, 2012   More...
SCF Ensures Meiotic Chromosome Segregation Through a Resolution of Meiotic Recombination Intermediates  Monday, January 23, 2012   More...
Hymyc1 Downregulation Promotes Stem Cell Proliferation in Hydra vulgaris  Monday, January 23, 2012   More...
Effects of Ligands on Unfolding of the Amyloid ß-Peptide Central Helix: Mechanistic Insights from Molecular Dynamics Simulations  Monday, January 23, 2012   More...
Pseudorabies Virus Infected Porcine Epithelial Cell Line Generates a Diverse Set of Host MicroRNAs and a Special Cluster of Viral MicroRNAs  Monday, January 23, 2012   More...
The Progeny of Arabidopsis thaliana Plants Exposed to Salt Exhibit Changes in DNA Methylation, Histone Modifications and Gene Expression  Monday, January 23, 2012   More...
Analysis of Global Sumoylation Changes Occurring during Keratinocyte Differentiation  Monday, January 23, 2012   More...
Paraquat, but Not Maneb, Induces Synucleinopathy and Tauopathy in Striata of Mice through Inhibition of Proteasomal and Autophagic Pathways  Monday, January 23, 2012   More...
Altered Neural and Behavioral Dynamics in Huntington's Disease: An Entropy Conservation Approach  Monday, January 23, 2012   More...
Childhood Adversity and Epigenetic Modulation of the Leukocyte Glucocorticoid Receptor: Preliminary Findings in Healthy Adults  Wednesday, January 25, 2012   More...
Biochemical Discrimination between Selenium and Sulfur 1: A Single Residue Provides Selenium Specificity to Human Selenocysteine Lyase  Wednesday, January 25, 2012   More...
Predicting the Impact of Alternative Splicing on Plant MADS Domain Protein Function  Wednesday, January 25, 2012   More...
Benchmarking and Analysis of Protein Docking Performance in Rosetta v3.2  Tuesday, August 02, 2011   More...
Biosensors Paving the Way to Understanding the Interaction between Cadmium and the Estrogen Receptor Alpha  Tuesday, August 02, 2011   More...
Sexual Phenotype Differences in zic2 mRNA Abundance in the Preoptic Area of a Protogynous Teleost, Thalassoma bifasciatum  Wednesday, August 03, 2011   More...
A Gene Optimization Strategy that Enhances Production of Fully Functional P-Glycoprotein in Pichia pastoris  Wednesday, August 03, 2011   More...
An Electronic Analog of Synthetic Genetic Networks  Thursday, August 04, 2011   More...
“Self-Assisted” Amoeboid Navigation in Complex Environments  Thursday, August 04, 2011   More...
Gold Nanoparticle-Based Surface-Enhanced Raman Scattering for Noninvasive Molecular Probing of Embryonic Stem Cell Differentiation  Thursday, August 04, 2011   More...
3D Multicolor Super-Resolution Imaging Offers Improved Accuracy in Neuron Tracing  Tuesday, January 24, 2012   More...
MicroRNA Signatures in Tumor Tissue Related to Angiogenesis in Non-Small Cell Lung Cancer  Wednesday, January 25, 2012   More...
microRNA-152 Mediates DNMT1-Regulated DNA Methylation in the Estrogen Receptor a Gene  Wednesday, January 25, 2012   More...
Resolving Structure and Mechanical Properties at the Nanoscale of Viruses with Frequency Modulation Atomic Force Microscopy  Wednesday, January 25, 2012   More...
Inhibition of Wnt/ß-Catenin Signaling by a Soluble Collagen-Derived Frizzled Domain Interacting with Wnt3a and the Receptors Frizzled 1 and 8  Friday, January 27, 2012   More...
ISL1 Directly Regulates FGF10 Transcription during Human Cardiac Outflow Formation  Friday, January 27, 2012   More...
Differential Role of PKC-Induced c-Jun in HTLV-1 LTR Activation by 12-O-Tetradecanoylphorbol-13-acetate in Different Human T-cell Lines  Friday, January 27, 2012   More...
Busulphan-Cyclophosphamide Cause Endothelial Injury, Remodeling of Resistance Arteries and Enhanced Expression of Endothelial Nitric Oxide Synthase  Friday, January 27, 2012   More...
Persistence of Cytosine Methylation of DNA following Fertilisation in the Mouse  Thursday, January 26, 2012   More...
SPPS: A Sequence-Based Method for Predicting Probability of Protein-Protein Interaction Partners  Thursday, January 26, 2012   More...
Biochemical Discrimination between Selenium and Sulfur 2: Mechanistic Investigation of the Selenium Specificity of Human Selenocysteine Lyase  Thursday, January 26, 2012   More...
Insights into the Mutation-Induced HHH Syndrome from Modeling Human Mitochondrial Ornithine Transporter-1  Thursday, January 26, 2012   More...
Non-Host Defense Response in a Novel Arabidopsis-Xanthomonas citri subsp. citri Pathosystem  Friday, January 27, 2012   More...
The Hedgehog Receptor Patched Is Involved in Cholesterol Transport  Thursday, September 08, 2011   More...
Key Role of Polyphosphoinositides in Dynamics of Fusogenic Nuclear Membrane Vesicles  Thursday, September 08, 2011   More...
Rationally Designed Interfacial Peptides Are Efficient In Vitro Inhibitors of HIV-1 Capsid Assembly with Antiviral Activity  Thursday, September 08, 2011   More...
Pub1p C-Terminal RRM Domain Interacts with Tif4631p through a Conserved Region Neighbouring the Pab1p Binding Site  Thursday, September 08, 2011   More...
Structure of Apo- and Monometalated Forms of NDM-1—A Highly Potent Carbapenem-Hydrolyzing Metallo-ß-Lactamase  Thursday, September 08, 2011   More...
High-Efficiency Screening of Monoclonal Antibodies for Membrane Protein Crystallography  Thursday, September 08, 2011   More...
Category Theoretic Analysis of Hierarchical Protein Materials and Social Networks  Thursday, September 08, 2011   More...
Qualitative and Quantitative Multiplexed Proteomic Analysis of Complex Yeast Protein Fractions That Modulate the Assembly of the Yeast Prion Sup35p  Tuesday, September 13, 2011   More...
X4 Tropic Multi-Drug Resistant Quasi-Species Detected at the Time of Primary HIV-1 Infection Remain Exclusive or at Least Dominant Far from PHI  Wednesday, August 24, 2011   More...
Spatial Association of Signaling Proteins and F-Actin Effects on Cluster Assembly Analyzed via Photoactivation Localization Microscopy in T Cells  Wednesday, August 24, 2011   More...
High Density Lipoprotein Structural Changes and Drug Response in Lipidomic Profiles following the Long-Term Fenofibrate Therapy in the FIELD Substudy  Wednesday, August 24, 2011   More...
Comprehensive Assessment of Host Responses to Ionizing Radiation by Nuclear Factor-?B Bioluminescence Imaging-Guided Transcriptomic Analysis  Wednesday, August 24, 2011   More...
Combined SAXS/EM Based Models of the S. elongatus Post-Translational Circadian Oscillator and its Interactions with the Output His-Kinase SasA  Wednesday, August 24, 2011   More...
Inverse Association between Methylation of Human Papillomavirus Type 16 DNA and Risk of Cervical Intraepithelial Neoplasia Grades 2 or 3  Wednesday, August 24, 2011   More...
In-cell NMR in E. coli to Monitor Maturation Steps of hSOD1  Wednesday, August 24, 2011   More...
Molecular Basis of NDM-1, a New Antibiotic Resistance Determinant  Wednesday, August 24, 2011   More...
Sustained Negative BOLD Response in Human fMRI Finger Tapping Task  Wednesday, August 24, 2011   More...
Spatial Frequency-Based Analysis of Mean Red Blood Cell Speed in Single Microvessels: Investigation of Microvascular Perfusion in Rat Cerebral Cortex  Wednesday, August 24, 2011   More...
Coordinated Regulation of ATF2 by miR-26b in ?-Irradiated Lung Cancer Cells  Thursday, August 25, 2011   More...
Quantitative Analysis of Phase Wave of Gene Expression in the Mammalian Central Circadian Clock Network  Friday, August 26, 2011   More...
Collective Dynamics of Active Cytoskeletal Networks  Friday, August 26, 2011   More...
Regulation of miR-146a by RelA/NFkB and p53 in STHdhQ111/HdhQ111 Cells, a Cell Model of Huntington's Disease  Friday, August 26, 2011   More...
Generation of Induced Pluripotent Stem Cells from CD34+ Cells across Blood Drawn from Multiple Donors with Non-Integrating Episomal Vectors  Tuesday, November 22, 2011   More...
Selenomethionine Incorporation into Amyloid Sequences Regulates Fibrillogenesis and Toxicity  Tuesday, November 22, 2011   More...
Evaluation of High-Throughput PCR and Microarray-Based Assay in Conjunction with Automated DNA Extraction Instruments for Diagnosis of Sepsis  Tuesday, November 22, 2011   More...
Effects of Solute-Solute Interactions on Protein Stability Studied Using Various Counterions and Dendrimers  Friday, November 18, 2011   More...
Microsecond Molecular Dynamics Simulations of Intrinsically Disordered Proteins Involved in the Oxidative Stress Response  Friday, November 18, 2011   More...
Shapes of Discoid Intracellular Compartments with Small Relative Volumes  Monday, November 21, 2011   More...
The Mechanism of Enhanced Insulin Amyloid Fibril Formation by NaCl Is Better Explained by a Conformational Change Model  Monday, November 21, 2011   More...
Modeling of Human Prokineticin Receptors: Interactions with Novel Small-Molecule Binders and Potential Off-Target Drugs  Monday, November 21, 2011   More...
Targeting of Mitochondria-Endoplasmic Reticulum by Fluorescent Macrocyclic Compounds  Monday, November 21, 2011   More...
Design and Analysis of Rhesus Cytomegalovirus IL-10 Mutants as a Model for Novel Vaccines against Human Cytomegalovirus  Monday, November 21, 2011   More...
Topological Structure of the Space of Phenotypes: The Case of RNA Neutral Networks  Tuesday, October 18, 2011   More...
Computer Simulations of Cell Sorting Due to Differential Adhesion  Tuesday, October 18, 2011   More...
Promoter Hypermethylation Mediated Downregulation of FBP1 in Human Hepatocellular Carcinoma and Colon Cancer  Wednesday, October 19, 2011   More...
Mechanism of Disruption of the Amt-GlnK Complex by PII-Mediated Sensing of 2-Oxoglutarate  Wednesday, October 19, 2011   More...
The Minimal Domain of Adipose Triglyceride Lipase (ATGL) Ranges until Leucine 254 and Can Be Activated and Inhibited by CGI-58 and G0S2, Respectively  Wednesday, October 19, 2011   More...
High-Dose siRNAs Upregulate Mouse Eri-1 at both Transcription and Posttranscription Levels  Wednesday, October 19, 2011   More...
Instability of the Octarepeat Region of the Human Prion Protein Gene  Wednesday, October 19, 2011   More...
Alternative Transcript Initiation and Splicing as a Response to DNA Damage  Wednesday, October 19, 2011   More...
Protein Kinase A Activity and Anchoring Are Required for Ovarian Cancer Cell Migration and Invasion  Wednesday, October 19, 2011   More...
Human Evolution and Osteoporosis-Related Spinal Fractures  Wednesday, October 19, 2011   More...
Structural Insight of Dopamine ß-Hydroxylase, a Drug Target for Complex Traits, and Functional Significance of Exonic Single Nucleotide Polymorphisms  Thursday, October 20, 2011   More...
Synergistic Post-Transcriptional Regulation of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) by miR-101 and miR-494 Specific Binding  Thursday, October 20, 2011   More...
A Pyrene Maleimide with a Flexible Linker for Sampling of Longer Inter-Thiol Distances by Excimer Formation  Thursday, October 20, 2011   More...
The Presence of the Iron-Sulfur Motif Is Important for the Conformational Stability of the Antiviral Protein, Viperin  Tuesday, February 21, 2012   More...
Low-Resolution Molecular Models Reveal the Oligomeric State of the PPAR and the Conformational Organization of Its Domains in Solution  Tuesday, February 21, 2012   More...
FKBP12 Activates the Cardiac Ryanodine Receptor Ca2+-Release Channel and Is Antagonised by FKBP12.6  Tuesday, February 21, 2012   More...
In Vivo MR Imaging of Pulmonary Perfusion and Gas Exchange in Rats via Continuous Extracorporeal Infusion of Hyperpolarized 129Xe  Tuesday, February 21, 2012   More...
The Mechanical Behavior of Mutant K14-R125P Keratin Bundles and Networks in NEB-1 Keratinocytes  Tuesday, February 21, 2012   More...
Asymmetric Stochastic Switching Driven by Intrinsic Molecular Noise  Tuesday, February 21, 2012   More...
The Importance of Craniofacial Sutures in Biomechanical Finite Element Models of the Domestic Pig  Tuesday, February 21, 2012   More...
Optical Tweezers as a New Biomedical Tool to Measure Zeta Potential of Stored Red Blood Cells  Tuesday, February 21, 2012   More...
Genes That Influence Swarming Motility and Biofilm Formation in Variovorax paradoxus EPS  Tuesday, February 21, 2012   More...
Protein-Protein Interactions in Clathrin Vesicular Assembly: Radial Distribution of Evolutionary Constraints in Interfaces  Wednesday, February 22, 2012   More...
Carbinolamine Formation and Dehydration in a DNA Repair Enzyme Active Site  Wednesday, February 22, 2012   More...
Systematic Validation of Protein Force Fields against Experimental Data  Wednesday, February 22, 2012   More...
Ligand Mobility Modulates Immunological Synapse Formation and T Cell Activation  Wednesday, February 22, 2012   More...
Cooperation of p300 and PCAF in the Control of MicroRNA 200c/141 Transcription and Epithelial Characteristics  Wednesday, February 22, 2012   More...
Modeling Pharmacodynamic Response to the Poly(ADP-Ribose) Polymerase Inhibitor ABT-888 in Human Peripheral Blood Mononuclear Cells  Monday, October 10, 2011   More...
Microcin H47 System: An Escherichia coli Small Genomic Island with Novel Features  Tuesday, October 11, 2011   More...
Structural Basis for Specific Binding of Human MPP8 Chromodomain to Histone H3 Methylated at Lysine 9  Wednesday, October 12, 2011   More...
Promiscuous Binding in a Selective Protein: The Bacterial Na+/H+ Antiporter  Wednesday, October 12, 2011   More...
SUMOylation of the Forkhead Transcription Factor FOXL2 Promotes Its Stabilization/Activation through Transient Recruitment to PML Bodies  Wednesday, October 12, 2011   More...
Analysis of RNA Binding by the Dengue Virus NS5 RNA Capping Enzyme  Wednesday, October 12, 2011   More...
Spreading of Alu Methylation to the Promoter of the MLH1 Gene in Gastrointestinal Cancer  Wednesday, October 12, 2011   More...
Identification and Characterization of a Novel Non-Coding RNA Involved in Sperm Maturation  Wednesday, October 12, 2011   More...
Gene Targeting of the Cysteine Peptidase Cathepsin H Impairs Lung Surfactant in Mice  Wednesday, October 12, 2011   More...
Dickkopf1 - A New Player in Modelling the Wnt Pathway  Wednesday, October 12, 2011   More...
Microfluidic Devices for Analysis of Spatial Orientation Behaviors in Semi-Restrained Caenorhabditis elegans  Wednesday, October 12, 2011   More...
A Computational Analysis of Limb and Body Dimensions in Tyrannosaurus rex with Implications for Locomotion, Ontogeny, and Growth  Wednesday, October 12, 2011   More...
Engineered Single-Domain Antibodies with High Protease Resistance and Thermal Stability  Wednesday, November 30, 2011   More...
Heterozygous Yeast Deletion Collection Screens Reveal Essential Targets of Hsp90  Wednesday, November 30, 2011   More...
Systematic Comparison of Three Methods for Fragmentation of Long-Range PCR Products for Next Generation Sequencing  Wednesday, November 30, 2011   More...
Constitutive versus Responsive Gene Expression Strategies for Growth in Changing Environments  Wednesday, November 30, 2011   More...
Scavenger Receptor Mediates Systemic RNA Interference in Ticks  Thursday, December 01, 2011   More...
Localization of ASV Integrase-DNA Contacts by Site-Directed Crosslinking and their Structural Analysis  Thursday, December 01, 2011   More...
Chemotaxis in Densely Populated Tissue Determines Germinal Center Anatomy and Cell Motility: A New Paradigm for the Development of Complex Tissues  Thursday, December 01, 2011   More...
Concentration Dependent Ion Selectivity in VDAC: A Molecular Dynamics Simulation Study  Friday, December 02, 2011   More...
ZipA Binds to FtsZ with High Affinity and Enhances the Stability of FtsZ Protofilaments  Friday, December 02, 2011   More...
Improving the Alignment Quality of Consistency Based Aligners with an Evaluation Function Using Synonymous Protein Words  Friday, December 02, 2011   More...
Bound Water at Protein-Protein Interfaces: Partners, Roles and Hydrophobic Bubbles as a Conserved Motif  Thursday, September 22, 2011   More...
Hydrophilic Aromatic Residue and in silico Structure for Carbohydrate Binding Module  Thursday, September 22, 2011   More...
Mitral Cells of the Olfactory Bulb Perform Metabolic Sensing and Are Disrupted by Obesity at the Level of the Kv1.3 Ion Channel  Thursday, September 22, 2011   More...
The Tissue-Specific Rep8/UBXD6 Tethers p97 to the Endoplasmic Reticulum Membrane for Degradation of Misfolded Proteins  Thursday, September 15, 2011   More...
Lucanthone and Its Derivative Hycanthone Inhibit Apurinic Endonuclease-1 (APE1) by Direct Protein Binding  Thursday, September 15, 2011   More...
The Phenotypic Radiation Resistance of CD44+/CD24-or low Breast Cancer Cells Is Mediated through the Enhanced Activation of ATM Signaling  Thursday, September 15, 2011   More...
Biophysical Studies of the Membrane-Embedded and Cytoplasmic Forms of the Glucose-Specific Enzyme II of the E. coli Phosphotransferase System (PTS)  Thursday, September 15, 2011   More...
Pseudomonas aeruginosa 4-Amino-4-Deoxychorismate Lyase: Spatial Conservation of an Active Site Tyrosine and Classification of Two Types of Enzyme  Thursday, September 15, 2011   More...
Protein-Protein Interactions in Crystals of the Human Receptor-Type Protein Tyrosine Phosphatase ICA512 Ectodomain  Thursday, September 15, 2011   More...
Eph/Ephrin Profiling in Human Breast Cancer Reveals Significant Associations between Expression Level and Clinical Outcome  Thursday, September 15, 2011   More...
Virtual High-Throughput Screening Identifies Mycophenolic Acid as a Novel RNA Capping Inhibitor  Thursday, September 15, 2011   More...
Molecular Mining of Alleles in Water Buffalo Bubalus bubalis and Characterization of the TSPY1 and COL6A1 Genes  Thursday, September 15, 2011   More...
Bone Marrow Stromal Cell Transplantation Mitigates Radiation-Induced Gastrointestinal Syndrome in Mice  Thursday, September 15, 2011   More...
Identification of a Negative Allosteric Site on Human a4ß2 and a3ß4 Neuronal Nicotinic Acetylcholine Receptors  Thursday, September 15, 2011   More...
Secreted Protein Acidic and Rich in Cysteine Is a Matrix Scavenger Chaperone  Friday, September 16, 2011   More...
Peptide Bond Distortions from Planarity: New Insights from Quantum Mechanical Calculations and Peptide/Protein Crystal Structures  Friday, September 16, 2011   More...
DRhoGEF2 Regulates Cellular Tension and Cell Pulsations in the Amnioserosa during Drosophila Dorsal Closure  Friday, September 16, 2011   More...
Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links  Wednesday, August 10, 2011   More...
Specificity of RSG-1.2 Peptide Binding to RRE-IIB RNA Element of HIV-1 over Rev Peptide Is Mainly Enthalpic in Origin  Wednesday, August 10, 2011   More...
Production of a Bioengineered G-Protein Coupled Receptor of Human Formyl Peptide Receptor 3  Thursday, August 11, 2011   More...
The Nucleotide Exchange Factor Ric-8A Is a Chaperone for the Conformationally Dynamic Nucleotide-Free State of Gai1  Thursday, August 11, 2011   More...
Characterization of 14-3-3 Proteins from Cryptosporidium parvum  Thursday, August 11, 2011   More...
Subunit Interface Residues F129 and H294 of Human RAD51 Are Essential for Recombinase Function  Friday, August 12, 2011   More...
Condensin I Recruitment to Base Damage-Enriched DNA Lesions Is Modulated by PARP1  Friday, August 12, 2011   More...
Species Accumulation Curves and Incidence-Based Species Richness Estimators to Appraise the Diversity of Cultivable Yeasts from Beech Forest Soils  Friday, August 12, 2011   More...
iNR-PhysChem: A Sequence-Based Predictor for Identifying Nuclear Receptors and Their Subfamilies via Physical-Chemical Property Matrix  Tuesday, February 21, 2012   More...
The Formation and Stabilization of a Novel G-Quadruplex in the 5'-Flanking Region of the Relaxin Gene  Tuesday, February 21, 2012   More...
Post-Transcriptional Regulation of 5-Lipoxygenase mRNA Expression via Alternative Splicing and Nonsense-Mediated mRNA Decay  Tuesday, February 21, 2012   More...
Transcriptional Repressor NIR Functions in the Ribosome RNA Processing of Both 40S and 60S Subunits  Monday, February 20, 2012   More...
Structural View of a Non Pfam Singleton and Crystal Packing Analysis  Monday, February 20, 2012   More...
Single Molecule Analysis Research Tool (SMART): An Integrated Approach for Analyzing Single Molecule Data  Monday, February 20, 2012   More...
Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells  Monday, February 20, 2012   More...
Small RNAs Targeting Transcription Start Site Induce Heparanase Silencing through Interference with Transcription Initiation in Human Cancer Cells  Monday, February 20, 2012   More...
Identification of Mammalian Protein Quality Control Factors by High-Throughput Cellular Imaging  Monday, February 20, 2012   More...
The Gac-Rsm and SadB Signal Transduction Pathways Converge on AlgU to Downregulate Motility in Pseudomonas fluorescens  Monday, February 20, 2012   More...
Discovery of Intramolecular Signal Transduction Network Based on a New Protein Dynamics Model of Energy Dissipation  Monday, February 20, 2012   More...
New Binding Mode to TNF-Alpha Revealed by Ubiquitin-Based Artificial Binding Protein  Monday, February 20, 2012   More...
An Improved Chloroplast DNA Extraction Procedure for Whole Plastid Genome Sequencing  Wednesday, February 22, 2012   More...
A 24-Hour Temporal Profile of In Vivo Brain and Heart PET Imaging Reveals a Nocturnal Peak in Brain 18F-Fluorodeoxyglucose Uptake  Wednesday, February 22, 2012   More...
The Aggregation and Neurotoxicity of TDP-43 and Its ALS-Associated 25 kDa Fragment Are Differentially Affected by Molecular Chaperones in Drosophila  Wednesday, February 22, 2012   More...
Identification of ATP-Binding Regions in the RyR1 Ca2+ Release Channel  Wednesday, November 07, 2012   More...
The Ca2+ Influence on Calmodulin Unfolding Pathway: A Steered Molecular Dynamics Simulation Study  Wednesday, November 07, 2012   More...
Distinct Effects of Guanidine Thiocyanate on the Structure of Superfolder GFP  Wednesday, November 07, 2012   More...
Measurement and Correction of Microscopic Head Motion during Magnetic Resonance Imaging of the Brain  Wednesday, November 07, 2012   More...
Tmod1 and CP49 Synergize to Control the Fiber Cell Geometry, Transparency, and Mechanical Stiffness of the Mouse Lens  Wednesday, November 07, 2012   More...
Structure and Mechanics of Supporting Cells in the Guinea Pig Organ of Corti  Wednesday, November 07, 2012   More...
Biomimetic and Live Medusae Reveal the Mechanistic Advantages of a Flexible Bell Margin  Wednesday, November 07, 2012   More...
Valproic Acid Induces Cutaneous Wound Healing In Vivo and Enhances Keratinocyte Motility  Wednesday, November 07, 2012   More...
Identifying Discrete States of a Biological System Using a Novel Step Detection Algorithm  Wednesday, November 07, 2012   More...
Effects of Growth and Mutation on Pattern Formation in Tissues  Wednesday, November 07, 2012   More...
On Ribosome Load, Codon Bias and Protein Abundance  Wednesday, November 07, 2012   More...
DNA Repair and Cell Cycle Biomarkers of Radiation Exposure and Inflammation Stress in Human Blood  Wednesday, November 07, 2012   More...
Nucleolin Participates in DNA Double-Strand Break-Induced Damage Response through MDC1-Dependent Pathway  Wednesday, November 07, 2012   More...
Role of Direct Repeat and Stem-Loop Motifs in mtDNA Deletions: Cause or Coincidence?  Wednesday, April 18, 2012   More...
The Role of Methylation in the Intrinsic Dynamics of B- and Z-DNA  Tuesday, April 17, 2012   More...
Conformational States of a Bacterial a2-Macroglobulin Resemble Those of Human Complement C3  Tuesday, April 17, 2012   More...
DNA Aptamers against the Lup an 1 Food Allergen  Tuesday, April 17, 2012   More...
Characterization and Evolution of microRNA Genes Derived from Repetitive Elements and Duplication Events in Plants  Monday, April 16, 2012   More...
Membranes with the Same Ion Channel Populations but Different Excitabilities  Monday, April 16, 2012   More...
The Fission Yeast RNA Binding Protein Mmi1 Regulates Meiotic Genes by Controlling Intron Specific Splicing and Polyadenylation Coupled RNA Turnover  Thursday, October 27, 2011   More...
Evaluation of Type-Specific Real-Time PCR Assays Using the LightCycler and J.B.A.I.D.S. for Detection of Adenoviruses in Species HAdV-C  Thursday, October 27, 2011   More...
Novel Sex Cells and Evidence for Sex Pheromones in Diatoms  Wednesday, October 26, 2011   More...
Atomic-Level Characterization of the Activation Mechanism of SERCA by Calcium  Thursday, October 27, 2011   More...
Characterizing Hospital Workers' Willingness to Respond to a Radiological Event  Thursday, October 27, 2011   More...
Multichannel Detrended Fluctuation Analysis Reveals Synchronized Patterns of Spontaneous Spinal Activity in Anesthetized Cats  Thursday, October 27, 2011   More...
Interactions between Upf1 and the Decapping Factors Edc3 and Pat1 in Saccharomyces cerevisiae  Monday, October 31, 2011   More...
Altered Antibiotic Transport in OmpC Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. coli  Friday, October 28, 2011   More...
Crystal Structure of Thrombin in Complex with S-Variegin: Insights of a Novel Mechanism of Inhibition and Design of Tunable Thrombin Inhibitors  Friday, October 28, 2011   More...
Predicting Residue-Residue Contacts and Helix-Helix Interactions in Transmembrane Proteins Using an Integrative Feature-Based Random Forest Approach  Friday, October 28, 2011   More...
Quantitative Bias in Illumina TruSeq and a Novel Post Amplification Barcoding Strategy for Multiplexed DNA and Small RNA Deep Sequencing  Friday, October 28, 2011   More...
Flip-Flop of Phospholipids in Proteoliposomes Reconstituted from Detergent Extract of Chloroplast Membranes: Kinetics and Phospholipid Specificity  Monday, December 12, 2011   More...
Membrane-Lipid Therapy in Operation: The HSP Co-Inducer BGP-15 Activates Stress Signal Transduction Pathways by Remodeling Plasma Membrane Rafts  Monday, December 12, 2011   More...
Identifying HER2 Inhibitors from Natural Products Database  Monday, December 12, 2011   More...
Chimeras of Escherichia coli and Mycobacterium tuberculosis Single-Stranded DNA Binding Proteins: Characterization and Function in Escherichia coli  Monday, December 12, 2011   More...
Insulin-Like Growth Factor-1 Receptor Is Regulated by microRNA-133 during Skeletal Myogenesis  Thursday, December 15, 2011   More...
Disorder Predictors Also Predict Backbone Dynamics for a Family of Disordered Proteins  Thursday, December 15, 2011   More...
Cigarette Smoking and p16INK4a Gene Promoter Hypermethylation in Non-Small Cell Lung Carcinoma Patients: A Meta-Analysis  Tuesday, December 13, 2011   More...
Resveratrol, by Modulating RNA Processing Factor Levels, Can Influence the Alternative Splicing of Pre-mRNAs  Tuesday, December 13, 2011   More...
Mutations Altering the Interplay between GkDnaC Helicase and DNA Reveal an Insight into Helicase Unwinding  Tuesday, December 13, 2011   More...