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Biochemistry - Computer Science

iPiG: Integrating Peptide Spectrum Matches into Genome Browser Visualizations
Published: Tuesday, December 04, 2012
Author: Mathias Kuhring et al.

by Mathias Kuhring, Bernhard Y. Renard

Proteogenomic approaches have gained increasing popularity, however it is still difficult to integrate mass spectrometry identifications with genomic data due to differing data formats. To address this difficulty, we introduce iPiG as a tool for the integration of peptide identifications from mass spectrometry experiments into existing genome browser visualizations. Thereby, the concurrent analysis of proteomic and genomic data is simplified and proteomic results can directly be compared to genomic data. iPiG is freely available from It is implemented in Java and can be run as a stand-alone tool with a graphical user-interface or integrated into existing workflows. Supplementary data are available at PLOS ONE online.