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Virus Shows Promise as Prostate Cancer Treatment, Virginia Polytechnic Institute Study


2/26/2013 7:17:50 AM

A recombinant Newcastle disease virus kills all kinds of prostate cancer cells, including hormone-resistant cells, but leaves normal cells unscathed, according to a paper published online ahead of print in the Journal of Virology. A treatment for prostate cancer based on this virus would avoid the adverse side effects typically associated with hormonal treatment for prostate cancer, as well as those associated with cancer chemotherapies generally, says corresponding author Subbiah Elankumaran of Virginia Polytechnic Institute, Blacksburg. The modified virus is now ready to be tested in preclinical animal models, and possibly in phase I human clinical trials.

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