Van Leeuwenhoeck Issues Research Note On Addex Therapeutics

Geneva, Switzerland, 8 June 2016 - Addex Therapeutics (SIX: ADXN), announced today that the independent life science research company Van Leeuwenhoeck has issued a research report on Addex Therapeutics. The research report estimates a current "risk-adjusted NPV (net present value) of CHF 6.5 per share" (ADXN closing price 7 June: CHF2.32).

"We see substantial upside potential in the Addex share price from the current level." commented Marcel Wijma, Chief Research Analyst at Van Leeuwenhoeck Institute "Addex has a substantial portfolio of clinical and late preclinical programs including a Phase III ready asset in a disease area with a market potential in the US alone of more than USD 2 billion."

The full analyst research report is available on www.leeuwenhoeck.com and on Addex website at www.addextherapeutics.com under Investors/downloads/analyst reports.

About Van Leeuwenhoeck Research and their research report

Van Leeuwenhoeck Institute, ("VLI") is actively engaged in the financial research of life sciences companies in Europe, North America, Australia and emerging markets such as Asia and India. The VLI team conducts fundamental financial research, independently from any specific broker, bank, or investor. A select circle of top analysts assists the firm in conducting fundamental biotech research according to the highest standards. The team's sector expertise, combined with an active network of well-respected scientists and biotech business analysts, adds value to VLI's research. VLI provides institutional investors and other professional investors with independent, un-biased research on the real value of innovative Life Sciences companies.

About Addex Therapeutics

Addex Therapeutics (www.addextherapeutics.com) is a biopharmaceutical company focused on the development of novel, orally available, small molecule allosteric modulators for neurological disorders. Addex lead drug candidate, dipraglurant (mGluR5 negative allosteric modulator or NAM) has successfully completed a phase IIa POC in Parkinson's disease levodopa-induced dyskinesia (PD-LID), and is being prepared to enter phase III for PD-LID with support from the Michael J. Fox Foundation for Parkinson's Research (MJFF). In parallel, dipraglurant's therapeutic use in dystonia is being investigated with support from the Dystonia Medical Research Foundation (DMRF). Addex second clinical program, ADX71149 (mGluR2 positive allosteric modulator or PAM) is being developed in collaboration with Janssen Pharmaceuticals, Inc for epilepsy. In addition, ADX71441 (GABAB receptor PAM) has received regulatory approval to start phase I and is being investigated for its therapeutic use in Charcot-Marie-Tooth Type 1A disease (CMT1A), alcohol use disorder and nicotine dependence. Discovery programs include mGluR4PAM for neurodegenerative diseases, mGluR7NAM for psychosomatic disorders and TrkBPAM for neurodegenerative disorders which are being advanced in collaboration with the Universities of Lausanne and Geneva under the Swiss CTI grant program; and mGluR3PAM which is being advanced in collaboration with Pierre Fabre Pharmaceuticals. Allosteric modulators are an emerging class of small molecule drugs which have the potential to be more specific and confer significant therapeutic advantages over conventional "orthosteric" small molecule or biological drugs. Addex allosteric modulator drug discovery platform targets receptors and other proteins that are recognized as essential for therapeutic intervention - the Addex pipeline was generated from this pioneering allosteric modulator drug discovery platform.

Press Contacts:
Tim Dyer
Chief Executive Officer
Addex Therapeutics
Telephone: +41 22 884 15 61
Email: PR@addextherapeutics.com

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