Vaccines That Alter Evolution

An evolutionary biologist has finally found experimental backing for a controversial idea that could change the course of vaccine development. In 2001, Penn State professor Andrew Read proposed that “leaky” vaccines – ones that allow transmission of disease organisms – might prompt the evolution of more dangerous strains.

Many existing vaccines are not leaky. People who get the standard vaccines for measles, mumps and rubella cannot pick up and transmit those diseases. Diseases such as measles, polio, mumps and smallpox prompt an immune response that gives lifelong protection and the vaccines are “perfect” because they mimic this response.

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