Unusual Mechanism of DNA Synthesis Could Explain Genetic Mutations, Georgia Institute of Technology Study
Researchers have discovered the details of how cells repair breaks in both strands of DNA, a potentially devastating kind of DNA damage. When chromosomes experience double-strand breaks due to oxidation, ionizing radiation, replication errors and certain metabolic products, cells utilize their genetically similar chromosomes to patch the gaps via a mechanism that involves both ends of the broken molecules. To repair a broken chromosome that lost one end, a unique configuration of the DNA replication machinery is deployed as a desperation strategy to allow cells to survive, the researchers discovered.
Hey, check out all the research scientist jobs. Post your resume today!