University of California, Los Angeles (UCLA) Scientists Design Masks to Hide Genetic Mutations from Cell
FINDINGS: UCLA scientists have devised a novel way to correct abnormal gene splicing ?a common mutation that often leads to disease. Splicing edits out the punctuation from a cell? genetic blueprint, enabling its code to dictate protein production by the cell. Using new technology made by Gene Tools of Oregon, the researchers designed a custom mask to camouflage each abnormal splice. The technique prevents the cell from seeing the genetic defects and restores splicing to the correct location in the gene.