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Turn Off Gene And Blood Vessels Don’t Sprout, University of North Carolina Study



4/30/2013 7:19:28 AM

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When researchers removed a gene called CASZ1 in frog embryos, the frogs failed to form branched and functional blood vessels. When they removed the CASZ1 gene from cultured human cells, scientists saw similar defects: the cells did not sprout or branch correctly due to their inability to maintain proper adhesions with the surrounding extracellular matrix.

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