Royston, UK – TTP LabTech has today announced a high throughput solution for chemotaxis research using the Acumen® eX3 microplate cytometer and the iuvo™ Chemotaxis Assay Plate from BellBrook Labs. Using this system, approximately four-fold time savings were achieved compared to a similar method using automated microscopy and off-line data processing.
The Acumen eX3 is a laser scanning microplate cytometer for the analysis of fluorescence in cell-based assays. In addition to offering enhanced multiplexing functionality, Acumen eX3 has a wide field of view that enables whole well and microchannel scanning. The iuvo™ Chemotaxis Assay Plate is a high-content, automation friendly microconduit array plate that facilitates horizontal chemotaxis in the presence of a defined gradient. The combination of Acumen eX3 with the iuvo microchannels results in a rapid and robust approach to neutrophil chemotaxis studies.
This exciting development offers scientists another assay that can be quickly and easily used as part of a primary screening oncology campaign.
Dr Paul Wylie, Acumen Product Manager, TTP LabTech comments, “This has proved a successful combination of products for customers involved with chemotaxis as the Acumen eX3 and iuvo plates offer an efficient alternative to the more traditional microscopy set-up requiring further off-line analysis.” he continued, “Setting up a good gradient often poses a challenge, but the iuvo plates eradicate this issue. The Acumen offers a fast and accurate analysis of the chemotaxis assay and whole well scanning enables multiple cell movements to be captured and analysed within any one well.”
For more information about Acumen, please visit www.ttplabtech.com/ products/acumen/index.html
About TTP LabTech Ltd
Based near Cambridge, UK, TTP LabTech supplies laboratory instrumentation and provides contract screening services for the healthcare, biotech and pharmaceutical sectors. TTP LabTech’s products are designed to increase efficiency, effectiveness, flexibility or overall capability in key biopharmaceutical research processes including compound storage (comPOUND®), low volume liquid handling (mosquito®), fluorescence detection (Acumen®) and antibody discovery (Mirrorball™).
About BellBrook Labs’ iuvo™ MicroConduit Array Technology
BellBrook Labs, LLC develops detection reagents and microfluidic devices that accelerate the discovery of more effective therapies for cancer and other debilitating diseases. The iuvo™ Microconduit Array technology is a line of unique microscale devices for miniaturization and automation of advanced cell models that are more representative of human physiology.