Trevena, Inc. to Present Results of TRV027 Phase 2a Study in Patients With Advanced Heart Failure

KING OF PRUSSIA, Pa.--(BUSINESS WIRE)--Trevena, Inc., the leader in the discovery and development of G-protein coupled receptor (GPCR) biased ligands, announced today that David Soergel, M.D., SVP of Clinical Development, will present the results of a Phase 2a study on the hemodynamic effects of TRV027 in patients with advanced heart failure with reduced ejection fraction, as a poster at the American College of Cardiology meeting, to be held in San Francisco on March 9th through 11th, 2013. The poster will be presented on Sunday, March 10th. Trevena successfully completed the Phase 2a study in October 2012, in which TRV027 was generally well-tolerated and produced a beneficial set of hemodynamic effects. Trevena is developing TRV027 for the intravenous hospital treatment of acute decompensated heart failure (ADHF), and the data being presented supports the advancement of TRV027 into further studies. A Phase 2b study to evaluate its clinical efficacy in patients with ADHF is currently being planned.