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Translational Genomics Research Institute (TGen) Researchers Identify Genetic Mutation That May Alter Tumor Cell Proliferation



7/5/2007 11:51:19 AM

Indianapolis, July 4, 2007 -- Researchers from Eli Lilly & Company and the Phoenix-based Translational Genomics Research Institute (TGen) today announced finding a novel recurring mutation of the gene AKT1 in breast, colorectal and ovarian cancers. The altered form of AKT1 appears to cause tumor cell proliferation and may play a role in making cells resistant to certain types of therapies. The findings are reported in an advance online publication (AOP) of the journal Nature.

Read at EurekAlert!


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