Transition Therapeutics Inc. Completes US $5 Million Private Placement

TORONTO, Nov. 22, 2011 (GLOBE NEWSWIRE) -- Transition Therapeutics Inc. ("Transition" or the "Company") (TSX:TTH.TO - News) (Nasdaq:TTHI - News) today announced the closing of its previously disclosed private placement financing issuing 3,703,703 common shares at a price of US$1.35 per share for gross proceeds of approximately US$5 million.

The proceeds from the offering are expected to be used to build value for Transition's partnered Alzheimer's disease compound ELND005, its diabetes program TT-401/402, and general corporate purposes.

These securities have not been registered under the U.S. Securities Act of 1933, as amended (the "Act"), and may not be offered or sold in the United States unless registered under the Act or unless an exemption from registration is available. This press release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of the securities in any State in which such offer, solicitation or sale would be unlawful.

About Transition

Transition is a biopharmaceutical company, developing novel therapeutics for disease indications with large markets. Transition's lead product is ELND005 (AZD-103) for the treatment of Alzheimer's disease and Transition also has an emerging pipeline of innovative preclinical and clinical drug candidates. The other drugs in the pipeline that the Company is developing are for anti-inflammatory and metabolic indications. Transition's shares are listed on the NASDAQ under the symbol "TTHI" and the Toronto Stock Exchange under the symbol "TTH". For additional information about the Company, please visit www.transitiontherapeutics.com.

Notice to Readers: Information contained in our press releases should be considered accurate only as of the date of the release and may be superseded by more recent information we have disclosed in later press releases, filings with the OSC, SEC or otherwise. Except for historical information, this press release may contain forward-looking statements, relating to expectations, plans or prospects for Transition, including conducting clinical trials. These statements are based upon the current expectations and beliefs of Transition's management and are subject to certain risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. These risks and uncertainties include factors beyond Transition's control and the risk factors and other cautionary statements discussed in Transition's quarterly and annual filings with the Canadian commissions.

The Toronto Stock Exchange has not reviewed and does not accept responsibility for the adequacy or accuracy of this release.

For further information on Transition, visit www.transitiontherapeutics.com

Contact:

Dr. Tony CruzChairman & Chief Executive OfficerTransition Therapeutics Inc.Phone: (416) 260-7770, x.223tcruz@transitiontherapeutics.comElie FarahPresident & Chief Financial OfficerTransition Therapeutics Inc.Phone: (416) 260-7770, x.203efarah@transitiontherapeutics.com

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