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Tissue Fusion To Commercialize Laser Surgical Device Developed At University of Colorado


2/19/2014 11:36:14 AM

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COLORADO SPRINGS, Colo., February 19, 2014 – Tissue Fusion and the University of Colorado recently completed a license agreement that will allow the company to continue developing a new surgical device that utilizes lasers, rather than staples and sutures, to close wounds during nasal surgery.

The two most common nasal surgeries are septoplasty (repair of deviated or deformed septum, thousands performed each year) and rhinoplasty (“nose job,” over 150,000 performed each year). Currently, wounds are closed during these surgeries using staples, sutures or intranasal packing, all of which can be dangerous (needles can break, and bleeding can occur) as well as uncomfortable for the patient. After the procedure, techniques like stapling or suturing can cause infection, scarring or other side effects.

Lasers have been used for decades in place of scalpels to cut tissues in procedures like LASIK eye surgery. Lasers also have the ability to ‘weld’ tissue together, but have not been widely used in this capacity due to the complexity of the laser (different parameters for different tissues) and the exceptional surgical skill required to use them.

A team led by mechanical and aerospace engineer Michael Larson, also the El Pomar Endowed Chair of Engineering and Innovation at the University of Colorado Colorado Springs, has developed a laser-based device for closing wounds during nasal surgery that circumvents these technical hurdles. The device generates heat and pressure to fuse tissue membranes together, but is designed specifically for use in septoplasty and rhinoplasty, using pre-set parameters to make the device easy to use by a surgeon or a trained medical technician. In addition to making the surgical procedure faster and simpler, the fusion device also has the potential to shorten healing time and reduce side effects like swelling, scarring, and infection.

Tissue Fusion is currently gathering data on the efficacy and safety of the device in controlled trials. The company will use the results in seeking approval from the FDA for clinical use in procedures related to the ear, nose and throat. Ultimately, the company hopes to introduce additional surgery-specific devices; further research by Larson’s team shows that the technology holds promise for “spot welding” layers of tissue in a range of surgeries, including microsurgical applications. "We’re pleased to be working in partnership with the University of Colorado to commercialize a new medical technology that is already adding jobs to the Colorado economy,” said Larson, who also serves as the company’s CEO.

“The technology licensed to Tissue Fusion has been a great example of Colorado’s innovation infrastructure, since it represents years of development efforts at MIND Studios in Colorado Springs, as well as a state grant to bring it closer to commercial readiness,” said Molly Markley of CU’s Technology Transfer Office. “We are looking forward to following the company’s progress as it moves towards FDA approval.” Tissue Fusion received a State of Colorado Early-Stage Company grant in 2013 under its Bioscience Discovery and Evaluation Grant program.

About Tissue Fusion

Tissue Fusion LLC is a medical device startup in Colorado Springs, CO, which is committed to creating a suite of wound closure instruments for improving surgical procedures and outcomes. The company is a spin-out from the University of Colorado Colorado Springs. Tissue Fusion is a recipient of an award from the State of Colorado’s Bioscience Discovery and Evaluation Grant Program, a program which is moving promising commercial technologies to market and supporting the development of the biotechnology industry in Colorado.

About the Technology Transfer Office and the University of Colorado

The CU Technology Transfer Office pursues, protects, packages, and licenses to business the intellectual property generated from research at CU. The TTO provides assistance to faculty, staff, and students, as well as to businesses looking to license or invest in CU technology. For more information about technology transfer at CU, visit www.cu.edu/techtransfer.

The University of Colorado is a premier public research university with four campuses: the University of Colorado Boulder, the University of Colorado Colorado Springs, the University of Colorado Denver and the University of Colorado Anschutz Medical Campus. Nearly 58,000 students are pursuing academic degrees at CU, and CU researchers attracted over $774M in research grants in FY2012-13. Academic prestige is marked by the university’s five Nobel laureates, eight MacArthur “genius” Fellows, 18 alumni astronauts and 19 Rhodes Scholars. For more information about the entire CU system, and to access campus resources, go to www.cu.edu.

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