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Thomas Scientific Names 'Red-Hot' Research Papers Of 2005

3/20/2006 12:53:21 PM

PHILADELPHIA and LONDON, March 20 /PRNewswire-FirstCall/ -- The New England Journal of Medicine leads the pack in this year's "Red-Hot Research Papers" rankings by publishing the most-cited research paper of 2005. This, according to the March/April issue of Science Watch - the bimonthly newsletter published by Thomson Scientific, a business unit of The Thomson Corporation.

New England Journal of Medicine (NEJM) boasts this ranking in a year that seems to have been dominated by highly cited articles in medical publications. Thirteen of the top-40 most-cited papers were published in NEJM, with four of the top-five most-cited articles appearing in its pages.

The research group led by Paul M. Ridker, Harvard University professor of medicine, tops the list of Red-Hot Research Papers for "C-reactive protein levels and outcomes after statin therapy," published in NEJM, January 2005. Ridker is also the only researcher to be listed as the first author on more than one paper - numbers one and 30.

"Our annual roundup of the hottest research papers celebrates researchers whose work influences modern scientific thought," said Christopher King, editor of Science Watch. "It also helps us spot trends and 'hot' fields of study. This year, for example, we see that many of the 'hottest' papers were published in medical publications."

The Red-Hot Research Papers of 2005 (Ordered by total citations per paper) Rank Name Paper Journal Citations 1 P.M. Ridker, "C-reactive protein New England 124 et al. levels and outcomes after Journal of Med. statin therapy" 2 G.H. Bardy, "Amiodarone or an New England 107 et al. implantable cardioverter- Journal of Med. defibrillator for congestive heart failure" 3 S.D. Solomon, "Cardiovascular risk New England 97 et al. associated with celecoxib Journal of Med. in a clinical trial for colorectal adenoma prevention" 4 R.S. "Cardiovascular events New England 93 Bresalier, associated with rofecoxib Journal of Med. et al. in a colorectal adenoma chemoprevention trial" 5 J.C. Barrett, "Haploview: analysis and Bioinformatics 90 et al. visualization of LD and haplotype maps" 6 S.E. Nissen, "Statin therapy, LDL New England 82 et al. cholesterol, C-reactive Journal of Med. protein, and coronary artery disease" 7 D.A. Hinds, "Whole-genome patterns Science 74 et al. of common DNA variation in three human populations" 8 L.P. Lim, "Microarray analysis shows Nature 73 et al. that some microRNAs downregulate large numbers of target mRNAs" 9 E.R. Miller, "Meta-analysis: High Annals of 73 et al. dosage vitamin E Internal supplementation may Medicine increase all-cause mortality" 10 A. Howell, "Results of the ATAC Lancet 69 et al. (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer"

By far, the field of medicine received the most attention in 2005, with 21 of the top-40 "Hottest Papers" appearing in medicine-focused publications. The two publications that appear most frequently on the list, NEJM and the Lancet, both fall into this category. Multidisciplinary publications (including Science and Nature, which appear third and fourth on the list, respectively), accounted for 10 of the papers included in the rankings.

Journal subject categories: (Ordered by number of Red-Hot Research Papers in the field) Number of Subject category "Red-Hot" Papers Medicine 21 Multidisciplinary 10 Biochemistry & Molecular Biology 4 Physics 2 Astronomy 1 Computer Science 1 Oncology 1 Journals: (Ordered by number of Red-Hot Research Papers published in the journal) Number of Publication "Red-Hot" Papers New England Journal of Medicine 13 Lancet 6 Science 5 Nature 4 Nucleic Acids Research 3 Physics Review Letter 2 Annals of Internal Medicine 1 Astronomy Journal 1 Bioinformatics 1 Cancer Cell 1 Cell 1 Journal of the Natn'l Cancer Institute 1 Nature Materials 1

The Science Watch rankings are part of the publication's annual rankings of the hottest researchers and papers of the year. For the rankings, Thomson Scientific evaluated the number of citations each paper received as indexed in its Web of Science(R) database (as of late December 2005). All of the papers listed in the rankings were published in 2005.

To learn about Science Watch's "Hottest Researchers of 2004-2005" or for more information about the hottest research papers, contact Rodney Yancey at 215-823-5397 or

About The Thomson Corporation

The Thomson Corporation (, with 2005 revenues of $8.7 billion, is a global leader in providing integrated information solutions to business and professional customers. Thomson provides value-added information, software tools and applications to more than 20 million users in the fields of law, tax, accounting, financial services, higher education, reference information, corporate e-learning and assessment, scientific research and healthcare. With operational headquarters in Stamford, Conn., Thomson has approximately 40,000 employees and provides services in approximately 130 countries. The Corporation's common shares are listed on the New York and Toronto stock exchanges .

Thomson Scientific is a business of The Thomson Corporation. Its information solutions assist professionals at every stage of research and development - from discovery to analysis to product development and distribution. Thomson scientific information solutions can be found at

NOTE: For information on subscribing to Science Watch, contact Rodney Yancey at 215-386-6362 or by email at

Thomson Scientific

CONTACT: Rodney Yancey, Manager, Corporate Communications, ThomsonScientific, +1-215-823-5397,; or Chris Lukach,Anne Klein & Associates, +1-856-988-6560 extension 15,, for Thomson Scientific

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