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The Proteins Ensuring Genome Protection, University of Geneva Study



2/13/2012 7:24:06 AM

Researchers from the University of Geneva (UNIGE), Switzerland, have discovered the crucial role of two proteins in developing a cell 'anti-enzyme shield'. This protection system, which operates at the level of molecular 'caps' named telomeres, prevents cells from treating chromosome ends like accidental DNA breaks and 'repairing' them. Joining chromosome ends would, indeed, lead to tumor formation. This study, carried out by Cyril Ribeyre and led by David Shore, professor of molecular biology, is published in the revue Nature Structural & Molecular Biology.

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