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The Dow Chemical Company (DOW) and Cambrex Corporation (CBM) to Manufacture Drug-Solubility Solution



2/14/2013 9:52:16 AM

HORGEN, Switzerland and KARLSKOGA, Sweden, Feb. 14, 2013 /PRNewswire/ -- Cambrex (NYSE: CBM) and The Dow Chemical Company (NYSE: DOW) have executed an agreement for Cambrex to contract manufacture Dow Hydroxypropyl Methylcellulose Acetate Succinate (HPMCAS) for Drug Solubility Enhancement.

This is the final step in building on the solubilization partnership that Dow and Bend Research announced in October 2012 and it will help Dow to commercially supply solubility enabling excipients. Construction has already begun on the new operational facility at Cambrex Karlskoga with commercial product availability set for year-end 2013. "Dow's polymer science and application expertise, coupled with Cambrex's capabilities positions Dow for rapid entry into the market. The AFFINISOL product platform has excellent manufacturing flexibility to match the diverse excipients needs of our customers' pipelines," said Bob Maughon, Senior R&D Director for Dow.

"We are enthusiastic about bringing the first solution of our AFFINISOLproduct range to the market," said Marc van Gerwen, Business Director for Dow. Van Gerwen added, "This agreement demonstrates our ability to promptly address with material science the pharmaceutical industry's most pressing need: advancing poorly soluble Active Pharmaceutical Ingredients to become therapeutically beneficial oral drug products."

"We are proud to be part of this collaboration with Dow," said Eric Neuffer, VP of Sales and Business Development for Cambrex. "This agreement between Dow and Cambrex further validates Cambrex's commitment to finding solutions that offer our clients quality products and services to meet a market need. This has been a great partnership with both the Dow and Cambrex teams focused on achieving project goals and objectives in a timely manner."

About Cambrex

Cambrex Corporation is an innovative life sciences company that provides products, services and technologies to accelerate the development and commercialization of small molecule therapeutics. The Company offers Active Pharmaceutical Ingredients (APIs), advanced intermediates and enhanced drug delivery products for branded and generic pharmaceuticals. Development and manufacturing capabilities include enzymatic biotransformations, high potency APIs, high energy chemical synthesis, controlled substances and formulation of finished dosage form products. For more information, please visit www.cambrex.com.

About Dow

Dow (NYSE: DOW) combines the power of science and technology to passionately innovate what is essential to human progress. The Company connects chemistry and innovation with the principles of sustainability to help address many of the world's most challenging problems such as the need for clean water, renewable energy generation and conservation, and increasing agricultural productivity. Dow's diversified industry-leading portfolio of specialty chemical, advanced materials, agrosciences and plastics businesses delivers a broad range of technology-based products and solutions to customers in approximately 160 countries and in high growth sectors such as electronics, water, energy, coatings and agriculture. In 2012, Dow had annual sales of $57 billion and employed approximately 54,000 people worldwide. The Company's more than 5,000 products are manufactured at 188 sites in 36 countries across the globe. References to "Dow" or the "Company" mean The Dow Chemical Company and its consolidated subsidiaries unless otherwise expressly noted. More information about Dow can be found at www.dow.com.

SOURCE The Dow Chemical Company; Cambrex Corporation


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