BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

Texas A&M University Teams with IBM Corporation (IBM) to Speed Drug Discovery for Tuberculosis


6/1/2010 12:14:01 PM

ARMONK, N.Y. and COLLEGE STATION, Texas, June 1 /PRNewswire-FirstCall/ -- IBM (NYSE: IBM) today announced that Texas A&M University used IBM supercomputing technology to carry out potentially life-saving tuberculosis research at a rate more than four times faster than was previously possible.

(Logo: http://www.newscom.com/cgi-bin/prnh/20090416/IBMLOGO )

Tuberculosis is an infectious disease that causes nearly two million deaths per year, with an estimated one-third of the human population carrying a latent infection (1).

The bacteria responsible for tuberculosis are mutating to form various drug-resistant strains. Texas A&M researchers are sequencing the DNA of the mutated strains so they can be tested against different drugs. In a race against time, researchers must try to find drugs that are effective before the strains mutate again. With IBM supercomputing technology, they can sequence the DNA of a specific strain in hours instead of days.

Scientists at the Texas A&M Supercomputing Facility built a software package called the "parallel Genome Analysis Pipeline" (pGAP) to help fight tuberculosis by more quickly analyzing the genome of mutated strains on the Facility's "Hydra" cluster -- a 832-core IBM POWER system coupled with a 20 terabyte (TB), third party storage system managed by the IBM General Parallel File System (GPFS), a high-performance, extremely scalable clustered file system.

Developed for IBM's AIX operating system and based on Illumina's Genome Analysis Pipeline, pGAP allows data to flow almost automatically from an Illumina Genome Analyzer IIx to the Hydra cluster, where it can quickly process in parallel the large datasets created by DNA sequencing. Using pGAP together with IBM supercomputing technology is boosting genomics research at Texas A&M.

"IBM's Power Systems provide the performance we need to rapidly process data while GPFS prevents bottlenecks," said Dr. Raffaele Montuoro, computational scientist at the Texas A&M Supercomputing Facility and inventor of pGAP. "When combined with the performance and capability of our own pGAP software, Texas A&M researchers are achieving greater success in the fight against tuberculosis."

The Texas A&M Supercomputing Facility recently increased its processing muscle even further with the addition of a 2,592-core IBM iDataPlex, a highly scalable system that can lower power, cooling and space requirements. Known as "Eos," the new cluster totals 27.14 teraflops, which made it 418th on the Top500 list of the world's fastest supercomputers announced May 31, 2010.

IBM

For more information on IBM visit www.ibm.com.

Texas A&M University

Opened in 1876 as Texas' first public institution of higher learning, Texas A&M University is a research-intensive flagship university with 38,000-plus undergraduates and more than 9,000 graduate students studying in over 250 degree programs in 10 colleges. Students can join any of 800 student organizations and countless activities ranging from athletics and recreation to professional and community service events.

Joanna Brewer

415-971-2777

jmbrewer@us.ibm.com



1.) World Health Organization: Global tuberculosis controlepidemiology, strategy, financing. http://www.who.int/tb/publications/global_report/2009/en/index.html .

SOURCE IBM



Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES