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TAP Biosystems Unveils 96-well 3D Cell Culture System at Zurich Conference - Novel Collagen-based Process Enables Physiologically Relevant Cell-Based Assays


3/9/2012 9:33:10 AM

08 March 2012 -- TAP Biosystems, a leading supplier of innovative automation and consumables for life science applications, is delighted to announce the introduction of a new RAFT™ (Real Architecture for 3D Tissue™) System on Stand 2 at the Dechema 3D Cell Culture Conference on March 14th -16th in Zurich, Switzerland. The system generates consistent and reproducible 3D cell cultures at physiologically relevant collagen concentrations, ideal for oncology and stem cell research.

On the stand, TAP Biosystems’ specialist team will demonstrate how the simple three step RAFT process of mix, make and measure simplifies the route to improved results from 3D experiments. They will show how scientists simply mix the reagents from the kit with their cells, pipette into 96-well plates and incubate on the plate heater for 30 minutes to form a cell-seeded collagen hydrogel. The RAFT plate is placed on the hydrogels, and in just 15 minutes the medium is absorbed gently, leaving cells “encapsulated” in physiological strength collagen, perfect for use in their cell-based assays.

TAP Biosystems’ development scientists will also present a poster entitled “New platform technology for simple, consistent production of collagen-based 3D cell cultures for physiologically relevant assays”. This details how using the RAFT system helps to create a realistic cellular environment to study cells’ complex behaviour and gives scientists complete control over their experimental parameters, including choice of cell types and cell seeding densities. The 3D cell cultures produced are ideally suited to cell-based secondary screening applications using a range of analytical techniques, such as cell proliferation assays and fluorescence imaging.

Dr Grant Cameron, TAP Biosystems’ RAFT Development Director stated: “There is an increasing interest in using 3D cell culture models for drug discovery because working with a more realistic cellular environment has the potential to improve compound selection. This is why we’re pleased to show our new RAFT system at 3D Cell Culture”.

Cameron continued: “Unlike other technologies, RAFT can deliver a range of collagen-based, reproducible 3D cell culture models that could provide more physiological relevant responses in for example, oncology and stem cell research. We look forward to welcoming scientists to Stand 2 and to demonstrating how RAFT’s simple, convenient workflow could make it possible for them to routinely incorporate 3D cell cultures in their screening programmes.”

For further information, please contact:

Matthew Walker, Head of Communications

York Way, Royston, Hertfordshire, SG8 5WY, UK

Tel: +44 1763 227200 Fax: +44 1763 227201



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