Sunshine Biopharma, Inc. Receives Scale-Up Manufacturing Protocol for Its Lead Anti-Cancer Compound, Adva-27a

MONTREAL--(Marketwire - October 09, 2012) - Sunshine Biopharma Inc. (OTCBB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it has received the Scale-Up Manufacturing Protocol from the Contract Manufacturing Organization (CMO) and is now poised to begin the process of manufacturing gram quantities of Adva-27a in preparation for conducting initial IND-Enabling studies. Adva-27a is Sunshine Biopharma's lead anti-cancer compound which has proven effective at killing Multidrug Resistant Breast Cancer cells (MCF-7/MDR) and Small-Cell Lung Cancer cells (H69AR). Initial or Pre-IND-Enabling studies include a variety of in vitro biological tests as well as studies in live rats and mice in order to ascertain that the scale-up manufacturing process generates a compound that is identical to the original used in the pre-clinical studies.

"We are very excited to be at the scale-up stage and have the capacity to manufacture gram quantities of our Adva-27a compound," said Mr. Camille Sebaaly, Sunshine Biopharma's CFO. "This is a very important milestone in our Adva-27a development program," he added.

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