DEDHAM, Mass., Jan. 24 /PRNewswire/ -- Signet Laboratories, Inc., a leading medical diagnostics/research company specializing in the development of monoclonal antibodies and diagnostic assays for cancer, infectious disease, and neurodegenerative disease, today announced the availability of monoclonal Cyclin E antibody.
Cyclin E, clone HE12, is a cell cycle protein that regulates G1-S phase transition in mammalian cells and is required for DNA synthesis. Aberrant expression of Cyclin E has been demonstrated in a multitude of malignancies.
Studies have implicated Cyclin E as a marker of unfavorable prognosis for some cancers, including breast and lung cancer. Signet's Cyclin E, clone HE12, recognizes human Cyclin E.
Signet's Cyclin E antibody offers investigators a valuable tool for cancer research. Cyclin E complements Signet's current cancer and cell cycle product portfolio which includes markers such as Cyclin D1, Cyclin E, HE4 and Hepsin.
About Signet Laboratories, Inc.
Signet Laboratories, Inc. (Signet, Dedham, MA) is a leading medical diagnostics/research company specializing in the development of monoclonal antibodies and diagnostic assays for cancer, infectious disease, and neurodegenerative disease. Signet was created in 1989 as a commercial spinout of Johnson & Johnson's Cambridge Research Laboratories, Inc. (CRL, Cambridge, MA).
The Company was founded to continue the mission originally established at CRL-the early detection and recurrence monitoring of patients with cancer and infectious disease. Signet has developed patented technology for diagnosis and recurrence monitoring and for risk assessment of asymptomatic patients in these areas. For more than a decade, the Company has aggressively maintained licensing and development programs, which are responsible for its broad patent and intellectual estate.
Contact Information
Company Contact Immunohistochemistry Contact
Colleen Scott Angela Thomas
Signet Laboratories, Inc. Signet Laboratories, Inc.
180 Rustcraft Road 180 Rustcraft Road
Dedham, MA 02026 Dedham, MA 02026
Phone: 781.915.1404 Phone: 781.915.1417
Fax: 781.461.2456 Fax: 781.461.2456
cscott@signetlabs.comathomas@signetlabs.com
Signet Laboratories, Inc.
CONTACT: Company contact: Colleen Scott, +1-781-915-1404,cscott@signetlabs.com, or Immunohistochemistry contact: Angela Thomas,+1-781-915-1417, athomas@signetlabs.com, both of Signet Laboratories, Inc.