Signet Laboratories, Inc. Announces Availability Of Seven New Monoclonal CEACAM Antibodies

DEDHAM, Mass., May 24 /PRNewswire/ -- Signet Laboratories, Inc., a leading medical diagnostics/research company specializing in the development of monoclonal antibodies and diagnostic assays for cancer, infectious disease, and neurodegenerative disease, today announced the availability of seven new monoclonal CEACAM antibodies.

CEA related cell adhesion molecules (CEACAM) are members of the carcinoembryonic antigen (CEA) family. The CEA family contains seven CEACAM and 11 pregnancy specific glycoproteins (PSG1-PSG11).

CEACAM is differentially expressed in leucocytes and epithelial cells, and certain CEA related cell adhesion molecules are upregulated in a variety of adenocarcimomas.

Signet will be offering the following CEACAM antibodies: CEACAM6 Clone 9A6 CEACAM5 Clone 26/3/13 CEACAM5 Clone 26/5/1 CEACAM1, 3, 4, 5, 6 Clone D14HD11 CEACAM5, 6 Clone MUS CEACAM1, 5, 6, 8 Clone TET2 CEACAM1 Clone GM8G5

The Signet CEACAM panel of monoclonal antibodies offers investigators a valuable tool for cancer research.

CEACAM complements Signet's current cancer and cell cycle product portfolio, which includes markers such as Cyclin D1, Cyclin E, HE4 and Hepsin.

About Signet Laboratories, Inc.

Signet Laboratories, Inc. (Signet, Dedham, MA) is a leading medical diagnostics/research company specializing in the development of monoclonal antibodies and diagnostic assays for cancer, infectious disease, and neurodegenerative disease. Signet was created in 1989 as a commercial spinout of Johnson & Johnson's Cambridge Research Laboratories, Inc. (CRL, Cambridge, MA).

The Company was founded to continue the mission originally established at CRL -- the early detection and recurrence monitoring of patients with cancer and infectious disease. Signet has developed patented technology for diagnosis and recurrence monitoring and for risk assessment of asymptomatic patients in these areas. For more than a decade, the Company has aggressively maintained licensing and development programs, which are responsible for its broad patent and intellectual estate. Contact Information Company Contact Immunohistochemistry Contact Colleen Scott Angela Thomas Signet Laboratories, Inc. Signet Laboratories, Inc. 180 Rustcraft Road 180 Rustcraft Road Dedham, MA 02026 Dedham, MA 02026 Phone: 781.915.1404 Phone: 781.915.1417 Fax: 781.461.2456 Fax: 781.461.2456 cscott@signetlabs.comathomas@signetlabs.com

Signet Laboratories, Inc.

CONTACT: Colleen Scott, +1-781-915-1404, cscott@signetlabs.com, or AngelaThomas, +1-781-915-1417, athomas@signetlabs.com, both Signet Laboratories,Inc.

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