Same Musicians Play a Brand New Tune: Unusual Interplay of Signaling Pathways Shapes Critical Eye Structure, Stowers Institute for Medical Research Study
5/15/2013 7:25:59 AM
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A small ensemble of musicians can produce an infinite number of melodies, harmonies and rhythms. So too, do a handful of workhorse signaling pathways that interact to construct multiple structures that comprise the vertebrate body. In fact, crosstalk between two of those pathways -- those governed by proteins known as Notch and BMP (for Bone Morphogenetic Protein) receptors -- occurs over and over in processes as diverse as forming a tooth, sculpting a heart valve and building a brain.
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