Hertfordshire, UK and Carlsbad, CA—July 30, 2012. -- Rothamsted Research has added TimeLogic’s latest J1-series Field Programmable Gate Array (FPGA) hardware to their computational tools platform. This
sophisticated technology will help Rothamsted scientists deliver the knowledge and
innovation for environmentally sustainable solutions for food and energy
agriculture, for example the 20:20 Wheat® Programme.
TimeLogic’s DeCypher systems greatly increase the speed of sequence comparison
by combining custom field programmable gate array (FPGA) circuitry with optimized
implementations of BLAST, Smith-Waterman, Hidden Markov Model and gene
modeling algorithms. With the inclusion of this additional TimeLogic hardware,
Rothamsted researchers now have a sizeable DeCypher system in-house, which
significantly enhances their high-throughput genome annotation efforts.
According to Michael Murray, Manager of Sales & Marketing for TimeLogic products
at Active Motif, “We have a long standing relationship with Rothamsted Research
and their funding agency, the Biotechnology and Biological Sciences Research
Council (BBSRC). This particular system represents an upgrade to an existing
DeCypher system and we’re very proud of the fact that Rothamsted Research, like
so many of our TimeLogic customers, continues to utilize our latest FPGA hardware
revisions. Our recently announced J1-series FPGA platform will run Tera-BLAST, our
accelerated BLAST implementation, over 960 times faster than running BLAST in
software.” Ted DeFrank, President of Active Motif added, “Recent advances in next-
generation DNA sequencing technology have created great opportunities for our
TimeLogic division and, as a result, Active Motif is investing heavily in this portion
of our business. In addition to a major hardware revision, TimeLogic has several
additional projects ongoing and we are excited about their continuation as we strive
to further strengthen our position as the leader in the field of FPGA-accelerated
Dr. Jan Taubert, a Senior Bioinformatician in the Department of Computational and
Systems Biology at Rothamsted - Harpenden added, “We are really excited about
the latest products from TimeLogic and are going to use them to assist with our
analysis of the recently sequenced wheat genome, process next generation DNA
sequencing data from our studies of the microbial biodiversity of soils and to
compare crop pathogen genomes” Prof. Christopher Rawlings, Head of the
Department of Computational and Systems Biology at Rothamsted - Harpenden
summarized, “The DeCypher system at Rothamsted is popular with our scientists
because of its great performance and the simple web-based user interface. The
increasing influx of next-generation DNA sequencing data and newly sequenced
genomes from species relevant to our research in sustainable agriculture has led to !
our decision to expand in-house analysis capacity with the new DeCypher system.
We are grateful to the support from the BBSRC that allowed us to make this new
investment in our research e-infrastructure.”
About Rothamsted Research
Rothamsted Research, the longest running agricultural research station in the
world, providing cutting-edge science and innovation for over 160 years. It receives
strategic funding from BBSRC to deliver the knowledge and new practices to
increase crop productivity and quality and to develop environmentally sustainable
solutions for food and energy production.
For further information, please contact Dr Darren Hughes, Head of
Communications, on +44 (0) 1582 763 133 ext 2673, email
BBSRC invests in world-class bioscience research and training on behalf of the UK
public. Our aim is to further scientific knowledge, to promote economic growth,
wealth and job creation and to improve quality of life in the UK and beyond.
Funded by Government, and with an annual budget of around £445M (2011-2012),
we support research and training in universities and strategically funded institutes.
BBSRC research and the people we fund are helping society to meet major
challenges, including food security, green energy and healthier, longer lives. Our
investments underpin important UK economic sectors, such as farming, food,
industrial biotechnology and pharmaceuticals.
For more information about BBSRC, our science and our impact see:
For more information about BBSRC strategically funded institutes see:
TimeLogic, a division of Active Motif, Inc, is the world leader in hardware
accelerated bioinformatics search tools which accelerate genome annotation by
combining optimized bioinformatics applications with powerful FPGA-based PCIe
accelerator cards. This blend of specialized hardware and optimized software
provides a perfect combination of performance, accuracy and value. Furthermore,
these systems are simple to maintain and scale easily. Utilizing a TimeLogic system
reduces pressure on over-used CPU-clusters by off-loading BLAST, Smith-
Waterman (SW) and Hidden Markov Model (HMM) tasks to a highly time and energy !
efficient solution. From the earliest genome sequencing projects in the 1990’s to
the largest Metagenomics projects undertaken to date, TimeLogic has provided the
enabling technology to make this research possible. Active Motif/TimeLogic
operates globally through its corporate headquarters in Carlsbad, California,
European headquarters in Rixensart, Belgium and Japanese headquarters in Tokyo,
Japan. Active Motif/TimeLogic applies a multi-disciplinary approach to create new
and modify existing technologies to meet the current and future needs of life
Find out more by visiting us at http://www.timelogic.com or contact Michael Murray