Roche xCELLigence System for Cell Analysis to Provide Predictive Mechanistic Information for Small Molecule Compounds

PENZBERG, Germany--(BUSINESS WIRE)--The extent to which protein targets are modulated by drugs or small molecule compounds depends on a number of factors, including the expression levels of the target, the effective concentration of the compound, and the time needed for the compound to perturb the target. One of the limitations of current multidimensional phenotypic profiling approaches is that typically a single time point is chosen to assess the effect of compounds. The conclusion, regarding the compounds´ mechanism of action, is based on the time point at which the samples are processed.