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Roche Applied Science Release: Functional Cell Profiling of Endogenous GPCRs Using the xCELLigence System


6/1/2010 10:39:14 AM

PENZBERG, Germany--(BUSINESS WIRE)--G-coupled protein receptors (GPCRs), also known as 7-transmembrane proteins, constitute the single largest class of therapeutic targets for clinical and investigational drugs. There are ~800 predicted members of this class in the human genome, involved in diverse signaling pathways in a wide array of cells and tissue types. Modulation of GPCR function has proven to have therapeutic benefit in a wide variety of diseases in immunology, neurology, cardiology, and oncology.

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