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Roche (RHHBY) Abandons Cholesterol Drug Trial on Poor Results


5/7/2012 7:56:18 AM

Roche is pulling the plug on the dal-Heart development program for its Phase III-stage CETP modulator dalcetrapib. The decision to end the program followed an independent data and safety monitoring board’s recommendation that one of the studies in patients with coronary heart disease (CHD) did not show clinically meaningful efficacy. The dal-Outcomes study had been evaluating whether combining dalcetrapib in combination with existing standard of care could lower the incidence of additional cardiovascular events in over 15,000 patients with stable coronary heart disease following an acute coronary syndrome.



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