"Ringo The Dog" Helps Find Potential New Therapy For Muscular Dystrophy

Ringo, a golden retriever, has made an important contribution to science by helping researchers discover a gene that inhibits the consequences of dystrophin loss in Duchenne muscular dystrophy (DMD). Even though Ringo carried the classic DMD mutation, he and one of his male offsprings had a variant in the Jagged1 gene that allowed them to walk and run freely, seemingly unaffected by the disease. The findings are from scientists at Boston Children’s Hospital, the Broad Institute of MIT and Harvard and the University of São Paulo in Brazil and were published online last November 12th 2015 in journal Cell.

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