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Quotient BioResearch Delivers New Insight Into Safety And Efficacy Of Cardiovascular, Diabetes And Obesity Drugs
9/30/2009 2:02:06 PM
30 September 2009, Fordham, Cambridgeshire, UK: Data from Quotient Bioresearch’s new extended lipid marker screen for assessing drug safety and efficacy was presented at the Institute of Biomedical Sciences (IBMS) annual congress in Birmingham (UK) this week
(28 – 30 September 2009). The range of markers included in the rapid screen extends the basic biochemistry panel currently used and provides a more comprehensive insight into the safety and efficacy of new drug compounds being evaluated for Coronary Vascular Disease (CVD), Coronary Heart Disease (CHD), diabetes and obesity.
With close to 200,000 deaths per annum in the attributed to diseases of the heart and circulatory system, they are the main cause of death in the United Kingdom. In 2006, CVD and CHD cost the UK healthcare system around £18 billion.
Triglycerides, cholesterol, LDL-Cholesterol and HDL-Cholesterol are currently measured in the clinical setting to predict Chronic Heart Disease. They are also used by pharmaceutical companies in the development of new drugs. Now, Quotient has validated a rapid screening panel which adds to this with: Apo A-1, Apo B-100, Apo C-Ill, Lp(a) (Lipoprotein a), and
NEFA (Non-esterified Fatty Acids).
Quotient’s director of bioanalytical sciences, Dr Jane Roberts commented:
“The expansion of the basic lipid screen gives drug developers a comprehensive insight into the performance of their new drugs. Markers such as Apo A1, B-100 and C-Ill are extremely useful pharmacodynamic biomarkers when evaluating secondary endpoint data as a metric of efficacy. Providing both safety and efficacy data in one analysis is also extremely cost effective.”
For more details about Quotient Bioresearch and the company’s unique Synthesis-to-Clinic™ drug development services,visit www.quotientbioresearch.com.
About Quotient Bioresearch
Quotient is a leading provider of drug development services with a focus on early-stage drug development services. The Company offers a unique range of drug development services through its three principal operating units – Quotient Radiochemistry & Metabolism, Quotient Bioanalytical Sciences (including Microbiology) and Quotient Clinical. Quotient has grown rapidly in the past three years, through a combination of both acquisition-led and organic growth. Quotient Bioresearch is part of Quotient Bioscience Group, which comprises Quotient Bioresearch, HFL Sport Science and Quotient Biodiagnostics.
For further information: www.quotientbioresearch.com