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Oxford Gene Technology Ltd. to Launch New Cancer Focused CytoSure™ Array at CCMC Meeting


7/30/2013 8:14:57 AM

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Oxford, UK – 30 July 2013. Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, will launch its new CytoSure™ Consortium Cancer +SNP array (4x180k) at the Cancer Cytogenomics Microarray Consortium (CCMC) and Cytogenomics Array Group (CAGdb) combined meeting in Chicago on the 5th- 7th August, booth 4.

The new CytoSure™ Consortium Cancer +SNP array allows the simultaneous detection of copy number variation (CNV) and loss of heterozygosity (LOH), with a SNP resolution that enables reporting of LOH at 10Mb. Focusing on content recommended by the CCMC, an international organisation of clinical cytogeneticists, molecular cytogeneticists and molecular pathologists, this targeted array covers over 500 cancer genes and 130 cancer-associated genomic regions for haematological malignancies and solid tumours. The CCMC-approved standardised array design is intended to improve clinical research quality and promotes collaboration and communication between cancer cytogenomics laboratories.

The new array will be the latest addition to a range of OGT microarrays specifically designed for detecting CNV and LOH on a single array for cancer research. This includes the recently released CytoSure Cancer +SNP array (4x180k) covering 1500 cancer associated genes and the CytoSure Haematological Cancer + SNP array (8x60k) focused specifically on haematological cancers. Due to the unique design of OGT’s SNP probes, there are no changes to the standard aCGH protocol, no restriction digest is required and any reference sample can be used. This enables the use of matched samples which is a particular advantage in cancer research, allowing constitutional abnormalities to be filtered out. For effortless data analysis, OGT’s CytoSure Interpret Software is supplied with all CytoSure arrays and delivers reliable and user-friendly data analysis, providing rapid access to meaningful results. James Clough, Executive Vice President Commercial at OGT, said: “The new CytoSure Consortium Cancer +SNP array is part of OGT’s commitment to advancing the field of cytogenetic cancer research. OGT’s collaborations in the design and development of our arrays with international organisations such as the CCMC who are leaders in cancer cytogenetics research, are testament to this. By providing reliable, high-quality CNV and SNP detection for haematological malignancies and solid cancers, these arrays are valuable tools for accurately and efficiently defining the genetic nature of cancers, advancing research into novel and improved therapeutics”.

Delegates of the CCMC / CAGdb meeting can find out more about OGT’s expertise in cancer cytogenetics by attending a talk by Ephrem Chin, Regional Sales manager at OGT, entitled ‘Oxford Gene Technology – Meeting laboratory needs’. The talk will be presented as part of the ‘Data quality and QC metrics’ workshop at 1 – 3pm on the 6th August and provides an opportunity for researchers to share in OGT’s extensive experience in high-throughput array processing and associated QC metrics and data analysis.

OGT representatives will also be available at booth 4 for the duration of the meeting.

For more information on OGT’s solutions for cytogenetic cancer research, please visit www.ogt.com/cancer.

For further information, please contact:

Oxford Gene Technology, Begbroke Science Park, Begbroke Hill, Woodstock Road, Begbroke, Oxfordshire, OX5 1PF, U.K.

T: +44 (0) 1865 856826 ; F: +44 (0) 1865 848684 ; E: contact@ogt.com

W: www.ogt.com ; Twitter: @OxfordGeneTech

About Oxford Gene Technology

Founded by Professor Ed Southern, Oxford Gene Technology (OGT) provides innovative genetics research and biomarker solutions to advance molecular medicine. The company has two trading businesses: Genomics comprises of CytoSure™ cytogenetics array, labelling and interpretation software products and services for the detection of chromosomal abnormalities, and Genefficiency™ Genomic Services, a unique combination of platforms, expertise and processing capabilities to deliver rapid, relevant genomic data. The Biomarkers business utilises proprietary next generation technologies to build a rich patent-protected portfolio of promising biomarkers for early stage cancer detection including advanced programmes in colorectal and prostate cancer plus the autoimmune disease systemic lupus erythematosus.

CytoSure™ and Genefficiency™ NGS browser/report: For Research Use Only; Not for Use in Diagnostic Procedures CytoSure: This product is provided under an agreement between Agilent Technologies, Inc., and OGT. The manufacture, use, sale or import of this product may be subject to one or more of U.S. patents, pending applications, and corresponding international equivalents, owned by Agilent Technologies, Inc. The purchaser has the non-transferable right to use and consume the product for RESEARCH USE ONLY AND NOT for DIAGNOSTICS PROCEDURES. It is not intended for use, and should not be used, for the diagnosis, prevention, monitoring, treatment or alleviation of any disease or condition, or for the investigation of any physiological process, in any identifiable human, or for any other medical purpose.

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