Oragenics, Inc. Receives Noncompliance Warning Letter From AMEX

ALACHUA, FL -- (MARKET WIRE) -- May 07, 2007 -- Oragenics, Inc. (AMEX: ONI) today reported it received a warning letter from the American Stock Exchange (AMEX) advising the Company that it does not meet certain of the continued listing standards as set forth in the AMEX Company Guide. Specifically, the Company is not in compliance with Sections 121(B)(2)(c), 802(a) and 803 of the AMEX Company Guide (the "Company Guide") which require that a Small Business Issuer (as defined in SEC Regulation S-B), such as the Company, must maintain a board of directors comprised of at least 50% independent directors, and an audit committee of at least two members, comprised solely of independent directors who also meet the requirements of Rule 10A-3 under the Securities Exchange Act of 1934. As a result of the recently announced resignation of Mr. George Hawes from our Board of Directors, the Company's Board of Directors is not comprised of at least 50% independent directors and our Audit Committee is not comprised of two independent members.