Zenosense: MIDS Quantitative Testing Commences
VALENCIA, SPAIN--(Marketwired - February 22, 2017) - Zenosense, Inc. (OTCQB: ZENO) ("Zenosense", the "Company"), a healthcare technology company primarily focused on the development and commercialization of MIDS Cardiac™, a Point of Care ("POC") handheld device for the early detection of certain cardiac event biomarkers to significantly accelerate the triage, diagnosis, treatment and disposition of patients reporting chest pain and with suspected acute myocardial infarction (heart attack), is pleased to announce that MIDS Medical Limited ("MML"), our joint venture based at Sci-Tech, Daresbury, has completed construction of two bench readers designed to test two methods of magnetic nanoparticle detection.
Following an initial bench rig evaluation phase in Q4, 2016 MML has designed and constructed two types of rigs to test its two related nano-magnetic detection systems; these rigs are designed to gather preliminary, definitive quantitative data under highly controlled conditions.
Priority testing has now commenced on the first of these rigs, a second iteration design designed to simulate MML's "Lab-on-Chip" detection method, whereby nanoparticles are dosed into wells on a "Test Slide" and located highly accurately in very close proximity to Hall effect magnetic sensors. This patented design is envisaged to be embodied in a commercial test strip where the Hall sensors will be integrated in a disposable test strip, the Hall sensors then being permanently and accurately located.
Testing is designed to methodically measure the detective ability of the MIDS system: Firstly, pure Magnetite nanoparticles in the sub-200 nanometer to 1 micrometer range are being tested. These particles are dosed in liquid suspension into the test slide wells in defined multi-nanolitre sized volumes. MML subsequently plans to test modern composite magnetic beads in the 1 to 3 micrometer range, such as those used in high sensitivity troponin assays. Initial testing of very small volumes of very small pure Magnetite nanoparticles has already produced encouraging results, with relatively large and clean detective signals being recorded. Based on these first results, MML expects it will be able to similarly detect magnetic beads which may have a lower magnetic signal density but higher individual volumes. MML expects refinements will be made to this simulation rig, to further improve reproducibility of results and to better inform design, prior to the production of a prototype Lab-on-Chip test strip.
A round of testing to a similar protocol is also planned on the second rig. This is a first iteration construction designed to explore the viability of a "Magnetic Bridge" structure for which MML submitted a patent application on January 19, 2017.
We believe that, in addition to cardiac markers, the MIDS technology platform can be applied across a wide spectrum of diagnostic tests. Proof of detection is the first step in applying the MIDS technology to cardiac markers and other immunoassay tests. The Company believes there is an enormous potential market for highly accurate cardiac marker assays conducted by a hand held device at the POC. The Company's target is to develop a hand-held device which can achieve Gold Standard laboratory accuracy or better, with results delivered at the POC within minutes.
About Zenosense, Inc.
Zenosense Inc.'s primary focus, through our joint venture ownership in MIDS Medical Ltd., is the development of a cost-effective, hand-held Point of Care rapid cardiac diagnostic device, MIDS Cardiac™, and is also the holder of an exclusive global license agreement to develop and market effective medical devices for use in hospitals and primary healthcare settings targeting the early detection of both deadly bacteria and certain cancers in the exhaled breath of patients.
To find out more about Zenosense (OTCQB: ZENO), visit our website at www.zenosense.com.
Forward-Looking Statements
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