BioSpace.com

Biotech and Pharmaceutical
News & Jobs
Search the Site
 
   
Biotechnology and Pharmaceutical Channel Medical Device and Diagnostics Channel Clinical Research Channel BioSpace Collaborative    Job Seekers:  Register | Login          Employers:  Register | Login  

NEWSLETTERS
Free Newsletters
Archive
My Subscriptions

NEWS
News by Subject
News by Disease
News by Date
PLoS
Search News
Post Your News
JoVE

CAREER NETWORK
Job Seeker Login
Most Recent Jobs
Browse Biotech Jobs
Search Jobs
Post Resume
Career Fairs
Career Resources
For Employers

HOTBEDS
Regional News
US & Canada
  Biotech Bay
  Biotech Beach
  Genetown
  Pharm Country
  BioCapital
  BioMidwest
  Bio NC
  BioForest
  Southern Pharm
  BioCanada East
  US Device
Europe
Asia

DIVERSITY

INVESTOR
Market Summary
News
IPOs

PROFILES
Company Profiles

START UPS
Companies
Events

INTELLIGENCE
Research Store

INDUSTRY EVENTS
Biotech Events
Post an Event
RESOURCES
Real Estate
Business Opportunities

 News | News By Subject | News by Disease News By Date | Search News
eNewsletter Signup
Miles
Km80.5

   

Ockham Overturns Vectura Group plc (VEC.L)'s Challenge to Secure European Patent Rights for Inhaled Heparin in the Treatment of COPD


6/3/2013 9:38:19 AM

Staying up-to-date has never been simpler. Sign up for the free GenePool newsletter today!

Swanwick, UK – 3 June 2013 – Ockham Biotech Ltd (‘Ockham’), a company specialising in the research, development and commercialisation of new therapies for respiratory disorders, is pleased to announce that its European patent covering the use of inhaled heparin for the treatment of patients with chronic obstructive pulmonary disease (COPD) and mucus hypersecretion has been restored, following its grant in 2008 and subsequent revocation in 2011.

In 2002, Ockham filed three patent applications based on the mucolytic properties of inhaled heparin that were discovered by Dr Janis Shute, Scientific Director for the Company. These properties provide a means to improve airway mucus clearance and a ‘ballistic effect’ to deliver other inhaled drugs to mucus-congested airways more effectively. In addition to its multiple pharmacological and well-described anti-inflammatory properties, the use of inhaled heparin suggests an effective way to treat mucus hypersecretory diseases with airway mucus congestion.

The first European patent on the use of inhaled heparin as a mono-therapy was granted to Ockham in 2008. The patent was subsequently opposed by Vectura plc and was revoked at first instance by the Opposition Division of the European Patent Office in 2011. In March 2013, the Technical Board of Appeal set aside the first instance decision of the Opposition Division and maintained Ockham’s European patent with claims directed to administration via inhalation, intranasally or instillation.

There is a high level of unmet need for drugs to reduce COPD exacerbation rates, slow or halt the progression of COPD, and improve lung function and the quality of life in COPD patients. The development of novel inhaled therapies, based on the multiple pharmacological properties of heparin, either alone or in combination with other drugs, is anticipated to provide new COPD treatment options, expanding the COPD market in the coming years.

Mario Cazzola, Professor of Medicine at the University of Rome Tor Vergata, said: “An effective mucolytic for the relief of symptoms in COPD patients with mucus hypersecretion is urgently needed. It will be a significant development in the therapeutic strategy for the millions of patients with COPD who suffer with symptoms of breathlessness, cough and difficulty expectorating mucus.”

Andy Short, CEO of Ockham Biotech, added, “The science behind Dr Shute’s discovery of the mucolytic effects of heparin is compelling. Her invention provides a way to treat airway mucus obstruction in COPD and Ockham’s commissioned and on-going trial of inhaled heparin in patients with COPD support the safety and efficacy of this approach. Securing this patent was an important step for our company and we look forward to exciting opportunities to work with potential partners”.

For more information, please contact:

Andy Short, CEO

Ockham Biotech

T: +44 1489 587 168 / +44 1489 565 115

E: as@ockhambiotech.com

For media enquiries, please contact:

Stefanie Bacher/ Gemma Howe

College Hill

T: +44 20 7866 7860

E: ockham@collegehill.com

About Ockham Biotech Ltd

Ockham Biotech Ltd. is a research and development company specialising in the development of inhaled heparin for the treatment of obstructive airway diseases, including chronic obstructive pulmonary disease (COPD). www.ockhambiotech.com

About COPD

COPD is predominantly caused by cigarette smoking and inhalation of environmental factors, including wood smoke from cooking over open fires, and is believed to affect up to 10% of the world population. In 2009, the COPD market was estimated to be worth $7.2 billion and is projected to grow at a compound annual growth rate (CAGR) of 7.4% to reach $11.9 billion in 2016 [GlobalData.com]. The COPD market is growing significantly in most countries and it is expected that COPD will be the fourth leading cause of death worldwide by 2030.



Help employers find you! Check out all the jobs and post your resume.


Read at BioSpace.com

   

ADD TO DEL.ICIO.US    ADD TO DIGG    ADD TO FURL    ADD TO STUMBLEUPON    ADD TO TECHNORATI FAVORITES