Novel Therapeutic Approaches to Cure Chronic HBV Infection, European Association for the Study of the Liver Reveals
4/25/2013 7:49:32 AM
Staying up-to-date has never been simpler. Sign up for the free GenePool newsletter today!
Exciting new data presented today at the International Liver Congress™ 2013 include results from early in vitro and in vivo studies targeting covalently closed circular DNA (cccDNA), which may form the basis of a cure for chronic hepatitis B virus (HBV) infection. HBV cccDNA is organized into mini-chromosomes within the nucleus of infected cells by histone and non-histone proteins. Despite the availability of efficient therapies against HBV, long-term persistence of cccDNA necessitates life-long treatments to suppress the virus. The following three experimental studies demonstrate effective HBV-cccDNA targeting/depletion using novel therapeutic approaches which offer the potential of a cure.
Hey, check out all the research scientist jobs. Post your resume today!
comments powered by