New Resistance Mechanism To Anti-HIV Drugs Discovered
A recent study at the Centro de Biología Molecular “Severo Ochoa”, (CSIC-UAM) discovers the existence of a mechanism that compensates for the lack of reverse transcriptase. This mechanism builds resistance to some drugs at preclinical development phase. A recently published study in the Journal of Molecular Biology directed by Dr. Luis Menéndez-Arias from the Centro de Biología Molecular “Severo Ochoa”, (CSIC-UAM) identifies the existence of compensating mechanisms for reverse transcriptase deficiency and suggests new resistance mechanisms to drugs in the preclinical development phase.