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New Class of Malaria Drugs Using Essential Calcium Enzyme Developed, University of Pennsylvania and University of California, San Francisco (UCSF) Study


12/28/2012 7:19:00 AM

Calpain, a calcium-regulated enzyme, is essential to a host of cellular processes, but can cause severe problems in its overactivated state. It has been implicated as a factor in muscular dystrophy, AIDS, Alzheimer's disease, multiple sclerosis, and cancer. As such, finding and exploiting calpain inhibitors is an important area of research.


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Malaria

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