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Neuron Transplant in Damaged Brain Fixes Obesity, Harvard University Study


11/28/2011 7:09:09 AM

A neuron transplant has rewired damaged brain areas in mice, raising hopes that similar transplants might one day help to treat spinal-cord injuries, Parkinson's disease and other brain conditions. Jeffrey Macklis at Harvard University and his colleagues took healthy neurons from mouse embryos that had been labelled with a green fluorescent protein. They used them to repair a brain circuit involved in the regulation of food intake and body weight in response to a hormone called leptin in mutant mice born with damage to that area, which become dangerously overweight as a result.

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