NEMUS Bioscience Announces Advancement Of Analgesic Program Utilizing NB2111, An Analogue Of Cannabidiol; Approaches Pain Management With A "Continuum Of Care" Strategy
Costa Mesa, Calif. (January 31, 2017) - NEMUS Bioscience, Inc. (OTCQB: NMUS) announced that the company has signed a research agreement with the University of Mississippi (UM) to further explore the analgesic and abuse-deterrent properties of NB2111, a unique analogue of cannabidiol (CBD). We expect that these planned in vivo studies will serve to complement and expand upon early data that showed NB2111 provided dose-dependent analgesia comparable to opioids in animals exposed to noxious stimuli. NB2111 also exhibited anti-addictive activity against opioids in a validated animal model of abuse liability.
Brian Murphy, M.D., M.B.A., Nemus CEO and Chief Medical Officer noted, “The global need for effective analgesics continues to grow with aging populations and the attendant conditions associated with diseases of old age. With research indicating a global pain management market potentially growing to $83 billion by 2024 (Transparency Market Research, 2016), Nemus plans to utilize its portfolio of cannabinoid-based therapies to develop a continuum of care for patients experiencing acute or chronic pain, as well as helping patients who may have developed an addiction to opioids convert to cannabinoid-class compounds that we believe offer analgesic coverage without the associated serious adverse safety profile associated with long-term opioid use.”
“According to the Centers for Disease Control (CDC), an average of 78 opioid-related overdose deaths occur each day in the United States while 650,000 opioid prescriptions are dispensed,” commented Dr. Kenneth J. Sufka, professor of Psychology and Pharmacology and Research Professor with the National Center for Natural Products Research at UM. “The opioid epidemic has reached extreme proportions and we feel having a safer yet effective alternative is vital to both national and global health. We believe these compounds will have utility in managing a spectrum of pain conditions, from the quality-of-life debilitating pain associated with fibromyalgia to intense post-surgical pain. Our team looks forward to working with Nemus to explore a variety of treatment options in anticipation of future human studies.”
“The company is happy to work with Professor Sufka, a recipient of the 2014 CASE-Carnegie Award as one of the pre-eminent educator-researchers in the country,” stated Dr. Murphy. “We expect to formally present this data at an upcoming peer-reviewed scientific meeting. Nemus plans to examine developmental partnering opportunities with companies who may already have a presence in this therapeutic area but are looking to expand their portfolio into cannabinoids and/or companies developing novel delivery systems, especially those that permit bypassing first-pass metabolism in the liver.”
Brian Murphy, M.D., M.B.A., Nemus CEO and Chief Medical Officer noted, “The global need for effective analgesics continues to grow with aging populations and the attendant conditions associated with diseases of old age. With research indicating a global pain management market potentially growing to $83 billion by 2024 (Transparency Market Research, 2016), Nemus plans to utilize its portfolio of cannabinoid-based therapies to develop a continuum of care for patients experiencing acute or chronic pain, as well as helping patients who may have developed an addiction to opioids convert to cannabinoid-class compounds that we believe offer analgesic coverage without the associated serious adverse safety profile associated with long-term opioid use.”
“According to the Centers for Disease Control (CDC), an average of 78 opioid-related overdose deaths occur each day in the United States while 650,000 opioid prescriptions are dispensed,” commented Dr. Kenneth J. Sufka, professor of Psychology and Pharmacology and Research Professor with the National Center for Natural Products Research at UM. “The opioid epidemic has reached extreme proportions and we feel having a safer yet effective alternative is vital to both national and global health. We believe these compounds will have utility in managing a spectrum of pain conditions, from the quality-of-life debilitating pain associated with fibromyalgia to intense post-surgical pain. Our team looks forward to working with Nemus to explore a variety of treatment options in anticipation of future human studies.”
“The company is happy to work with Professor Sufka, a recipient of the 2014 CASE-Carnegie Award as one of the pre-eminent educator-researchers in the country,” stated Dr. Murphy. “We expect to formally present this data at an upcoming peer-reviewed scientific meeting. Nemus plans to examine developmental partnering opportunities with companies who may already have a presence in this therapeutic area but are looking to expand their portfolio into cannabinoids and/or companies developing novel delivery systems, especially those that permit bypassing first-pass metabolism in the liver.”