Lille (France), Cambridge (Massachusetts – USA), May 4, 2011– Naturalpha, international consulting and clinical
research company in Nutrition and Health, partner of Food and Pharmaceutical Industries, is proud to announce
that its Clinical Investigation Center in Nutrition (CNCN) perfectly meets the expectations and needs of industrials
focused on Nutrition & Health.
> A year that allowed to demonstrate the relevance of the offer and provided services
In 2010, Naturalpha conducted several clinical studies on behalf of French and international clients (ingredients
suppliers, food supplements and functional food industries). These studies were fully conducted by Naturalpha from the
protocol up to the delivery of the results and final clinical report to the client. The study duration varied from a few weeks
to several months. These studies occurred at different stages of product development, such as bioavailability or
tolerance studies, proof of concept or efficacy on health effects of ingredients or finished products (functional foods and
food supplements) containing plant extracts, prebiotics, probiotics, vitamins, minerals, fatty acids.... Several health topics
have been and will be addressed in the coming months within the CNCN such as weight management, cholesterol,
glucose metabolism, immune modulation, gut health, constipation, menopause, vision...
In addition, a major cohort-monitoring research project in cardiometabolic disorders will be also launched.
These activities during the first year also highlighted the relevance of the partnership with the Hospital (a member of the
GHICL) which allowed an access to the laboratories and very specific technologies such as the DEXA scan (for the
evaluation of the fat mass), measurement of colonic transit time… These tools are especially useful to run clinical trials
according to EFSA standards.
> Promising preliminary findings of the completed clinical studies and future trials
In the field of weight management, a study in weight management recently completed with around hundred volunteers
confirmed a very good compliance mainly linked to the high quality of the clinical team. Despite several visits and
intensive examinations such as DEXA scan, the dropout rate of volunteers remained very low. Also in others studies
where the volunteers have to stay several hours in the center for a glucose tolerance test the readiness for participation
and high compliance is confirmed. Studies such as to compare the bioavailability (proportion of the substance that
reaches the bloodstream) of active ingredients in food supplements in liquid and dry dosage forms (tablets, capsules,
syrup...) have also been conducted in the center. First results on the studies completed are very promising and will
contribute largely to the development of future health products and ingredients.
Building on its success, Naturalpha has increased demands from companies to perform studies in its clinical
investigation center with permanent launches of new studies for EFSA Health Claim dossiers in different fields (such as
vision, blood pressure, satiety, menopause, constipation…).
> Satisfied volunteers involved in healthy food
The majority of participants in clinical trials in nutrition have through satisfaction questionnaires emphasized the quality of
care within the center, the availability of the team and the transparency on the studies and products tested. Not only did
volunteers contribute to advance science and develop tomorrow’s products in compliance with the strictest conditions
they also particularly appreciated the opportunity to learn more about their eating habits. When launching its clinical
center Naturalpha has indeed also promised to contribute in the education of volunteers towards a responsible eating
The full medical checkup performed on each volunteer before joining any study, the analysis of their eating habits
combined with regular monitoring of their diet, make them more aware of the regional health issues, such as obesity and
cardiometabolic disorders. This prevention aspect is part of the long term strategy led by Naturalpha within the regional
Nutrition Health Longevity cluster. - Press Release – May 4, 2011 - Press Release -
Jean-François Jeanne, Clinical Study Director at the CNCN: «This first year of activity has shown the relevance of
our clinical trials offer in nutrition coping with the EFSA regulation on Health Claim dossiers. Our access to the Hospital
facilities allowed Naturalpha to fully manage the clinical trials in its investigation center (CNCN) complying with the strict
timelines and high compliance of the volunteers. Our large volunteers database, the skills of our operational team:
nutritionists, doctors, technicians ... have allowed us to complete three major studies and meet the expectations of our
customers involved in nutrition and health. Other studies are ongoing and, new studies will be launched. This, together
with the large increase of volunteers that subscribe at our database, confirms Naturalpha’s great enthusiasm for the
second year of its center. »
About Naturalpha’s Clinical Nutrition Center (CNCN)
The CNCN is located within the Hospital Saint Vincent de Paul, a major hospital in the center of Lille. The team is
composed of physicians, nurses, clinical technicians and has access to a wide expertise, equipments, services and
facilities of the Hospital.
The CNCN is designed in order to fully meet the needs of a clinical study in nutrition with healthy volunteers in facilities at
the forefront of technology and in accordance with the high standards of safety and hygiene.
For more information on the CNCN: www.cncn.naturalpha.com
Clinical nutrition studies
The study, with a duration of several months is performed in humans to evaluate the characteristics, effects and safety of
functional ingredients, food supplements and finished foods. The conditions for a clinical study are strictly defined and
regulated by law. Finally, the study participation must be voluntary. Every clinical trial must be approved in advance and
monitored by an ethics committee consisting of physicians, statisticians, lawyers, and representatives of civil society etc.,
to ensure that risks are as low as possible in relation to the expected and verified benefits.
Naturalpha, specialized in consulting, scientific and clinical research in Nutrition and Health, offers functional ingredients,
food supplements and finished food manufacturers’ solutions to build a relevant research strategy. Naturalpha supports
its industrial partners in building the proof of "health effect" of their innovative products at every stage of their
development by proposing scientific and regulatory intelligence, consulting, health claim dossier audit, preclinical and
clinical studies. Spin-off of the biotechnology company Genfit, Naturalpha is located in Lille with an office in Cambridge
(Massachusetts, USA). Naturalpha employs 25 specialists (physicians, engineers, research scientists and dieticians) and
is a member of the Nutrition Health Longevity Competitivity Cluster. www.naturalpha.com
Marleen VAN D’HUYNSLAGER
Phone: (+33) 3 20 95 95 08
MILESTONES – PR
Phone: (+33) 1 75 44 87 42