MARTINSRIED, GERMANY and MUNICH, GERMANY--(Marketwire - February 08, 2013) - MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) today announced that the
US Patent and Trademark Office (USPTO) has granted the first patent
Company's latest antibody platform Ylanthia, which became commercially
for existing and new partners in 2012.
"A growing patent portfolio on our new antibody platform Ylanthia
important factor for a successful partnering process in our core
markets, which we intend to intensify during the course of 2013",
Marlies Sproll, Chief Scientific Officer of MorphoSys AG.
The new patent (US 8,367,586) covers the composition of MorphoSys's
antibody library. Ylanthia comprises more than 100 billion distinct, fully
antibodies, which makes it the industry's largest known antibody Fab
uses 36 fixed, naturally-occurring heavy and light chain framework
which translates into unprecedented structural diversity. The
diversity is expected to result in antibodies against previously
target molecules and unique epitope coverage.
Ylanthia's antibody frameworks were pre-selected for expression
stability and aggregation behavior. A shift towards higher stability and
tolerance will increase shelf life and serum stability of resulting
products, making them more cost-effective to produce and administer. A
solubility in turn opens up the path for more convenient ways of
to the benefit of patients. When needed, antibodies from the Ylanthia
are optimized using MorphoSys's proprietary Slonomics technology.
enables optimization of Ylanthia antibodies with unprecedented speed
MorphoSys developed HuCAL, the most successful antibody library technology
the pharmaceutical industry. By successfully applying this and other
technologies, MorphoSys has become a leader in the field of therapeutic
antibodies, one of the fastest-growing drug classes in human healthcare.
Together with its pharmaceutical partners, MorphoSys has built a
pipeline of more than 70 human antibody drug candidates for the treatment
cancer, rheumatoid arthritis, and Alzheimer's disease, to name just a few.
its ongoing commitment to new antibody technology and drug development,
MorphoSys is focused on making the healthcare products of tomorrow.
listed on the Frankfurt Stock Exchange under the symbol MOR. For regular
about MorphoSys, visit http://www.morphosys.com.
HuCAL®, HuCAL GOLD®, HuCAL PLATINUM®, CysDisplay®,
Ylanthia® and 100 billion high potentials® are registered
Slonomics(®) is a registered trademark of Sloning BioTechnology
subsidiary of MorphoSys AG.
This communication contains certain forward-looking statements
MorphoSys group of companies. The forward-looking statements contained
represent the judgment of MorphoSys as of the date of this release and
risks and uncertainties. Should actual conditions differ from the
assumptions, actual results and actions may differ from those
MorphoSys does not intend to update any of these forward-looking
far as the wording of the relevant press release is concerned.
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Source: MorphoSys AG via Thomson Reuters ONE