Montreal Researchers Identify Defects Of Immune Cells

Researchers at Université de Montréal and the Institut de recherches cliniques de Montréal (IRCM) have successfully identified a defective immune cell population that determines susceptibility to candidiasis, a common and often debilitating infection in individuals infected with the human immunodeficiency virus (HIV). These findings, revealed using a model of candidiasis in transgenic mice expressing HIV developed by the same research group, represents a milestone in developing a treatment for the infection and, eventually, preventing it. They are described in an article of the July 1st issue of The Journal of Immunology.